Heuer-Jungemann lab
@ameliehj.bsky.social
Professor for Hybrid BioNanoSystems @TU Dortmund and Research Center One Health Ruhr. Formerly Emmy Noether Research Group Leader @MPI Biochem.
We use (silicified) DNA origami to study and manipulate proteins for biomedicine and biocatalysis.
We use (silicified) DNA origami to study and manipulate proteins for biomedicine and biocatalysis.
⚠️ New Paper Alert ⚠️
We showed that penetration of DNA origami structures 🧬 into cancer spheroids depends mostly on size, BUT, their ability to fully eradicate ALL viable cells in the tumoroid, depends on the way ligands are attached 😱 Wanna know more? --> onlinelibrary.wiley.com/doi/10.1002/...
We showed that penetration of DNA origami structures 🧬 into cancer spheroids depends mostly on size, BUT, their ability to fully eradicate ALL viable cells in the tumoroid, depends on the way ligands are attached 😱 Wanna know more? --> onlinelibrary.wiley.com/doi/10.1002/...
Effects of DNA Origami‐Based Nanoagent Design on Apoptosis Induction in a Large 3D Cancer Spheroid Model
The ability of DNA origami to penetrate through spheroid tissue and to induce cell death via the extrinsic apoptosis pathway is examined. Both structure of the DNA origami and the attachment of the a...
onlinelibrary.wiley.com
April 25, 2025 at 1:00 PM
⚠️ New Paper Alert ⚠️
We showed that penetration of DNA origami structures 🧬 into cancer spheroids depends mostly on size, BUT, their ability to fully eradicate ALL viable cells in the tumoroid, depends on the way ligands are attached 😱 Wanna know more? --> onlinelibrary.wiley.com/doi/10.1002/...
We showed that penetration of DNA origami structures 🧬 into cancer spheroids depends mostly on size, BUT, their ability to fully eradicate ALL viable cells in the tumoroid, depends on the way ligands are attached 😱 Wanna know more? --> onlinelibrary.wiley.com/doi/10.1002/...
📣NEW PAPER ALERT ⚠️
Finally out in Nature Communications, after unfortunately spending almost 1 year under review at Nature Materials 🤐
But very very pround of this work that was spearheaded by extremely talented PhD student Moritz Weck:
www.nature.com/articles/s41...
Finally out in Nature Communications, after unfortunately spending almost 1 year under review at Nature Materials 🤐
But very very pround of this work that was spearheaded by extremely talented PhD student Moritz Weck:
www.nature.com/articles/s41...
Fully addressable designer superstructures assembled from one single modular DNA origami - Nature Communications
Methods for creating large DNA assemblies with low cost and enhanced structural control are of interest. Here, the authors report moDON (modular DNA origami nanostructure) that combines two approaches...
www.nature.com
February 12, 2025 at 3:03 PM
📣NEW PAPER ALERT ⚠️
Finally out in Nature Communications, after unfortunately spending almost 1 year under review at Nature Materials 🤐
But very very pround of this work that was spearheaded by extremely talented PhD student Moritz Weck:
www.nature.com/articles/s41...
Finally out in Nature Communications, after unfortunately spending almost 1 year under review at Nature Materials 🤐
But very very pround of this work that was spearheaded by extremely talented PhD student Moritz Weck:
www.nature.com/articles/s41...
Yesterday the very first PhD student from my group successfully defended her thesis 🤩
Congratulations Dr. Wassermann - I'm proud of you!
#proudPI
Congratulations Dr. Wassermann - I'm proud of you!
#proudPI
February 11, 2025 at 2:44 PM
Yesterday the very first PhD student from my group successfully defended her thesis 🤩
Congratulations Dr. Wassermann - I'm proud of you!
#proudPI
Congratulations Dr. Wassermann - I'm proud of you!
#proudPI