Amesh Adalja
@ameshaa.bsky.social
Infectious Disease • Critical Care • EM Physician
Independent voice on outbreaks, biosecurity & biothreat preparedness
Pittsburgh • NYC
Independent voice on outbreaks, biosecurity & biothreat preparedness
Pittsburgh • NYC
“You cannot make a return on investment if you don't have access to the U.S. market, or because of delays—regulatory-wise—or because your market is much smaller, because you don't have a recommendation by the government,” www.fiercebiotech.com/biotech/anti...
Anti-vaccine sentiment pushes Moderna away from new late-stage infectious disease trials
As the Trump administration erodes U.S. | As the Trump administration erodes U.S. infrastructure supporting infectious disease vaccines, mRNA heavyweight Moderna plans to pull away from late-stage cli...
www.fiercebiotech.com
January 26, 2026 at 1:46 PM
“You cannot make a return on investment if you don't have access to the U.S. market, or because of delays—regulatory-wise—or because your market is much smaller, because you don't have a recommendation by the government,” www.fiercebiotech.com/biotech/anti...
“You can see others bring their kitchen utensils and wash them right here and also wash their clothes..This is the water that is causing cholera.” apnews.com/article/afri...
Malawi rolls out cholera vaccines as rains and floods raise the threat of deadly outbreaks
The southern African nation of Malawi has started a cholera vaccination rollout this week in a bid to stem the threat of a disease that kills tens of thousands of people globally each year.
apnews.com
January 26, 2026 at 1:04 PM
“You can see others bring their kitchen utensils and wash them right here and also wash their clothes..This is the water that is causing cholera.” apnews.com/article/afri...
“A source of the Tennessee outbreak near Nashville in Williamson and Maury counties has not been identified.” www.healio.com/news/infecti...
Histoplasmosis outbreak sickens dozens in Tennessee
At least 36 people have been sickened in a histoplasmosis outbreak in middle Tennessee, according to state health officials, who said they are investigating potential deaths linked to the cluster.
His...
www.healio.com
January 26, 2026 at 1:03 PM
“A source of the Tennessee outbreak near Nashville in Williamson and Maury counties has not been identified.” www.healio.com/news/infecti...
“There is a need to create transparent strategies to update lists of immunotherapies, consolidate & harmonize recommendations across clinical resources & develop & implement tools for reducing gaps in screening for immunotherapies w/..risk of TB” www.infectiousdiseaseadvisor.com/news/tubercu...
Tuberculosis Screening Gaps Possible in the Evolving Immunotherapy Landscape
Prescribing information and clinical guidelines showed gaps in TB screening protocols for many recently approved targeted immunotherapies.
www.infectiousdiseaseadvisor.com
January 26, 2026 at 1:01 PM
“There is a need to create transparent strategies to update lists of immunotherapies, consolidate & harmonize recommendations across clinical resources & develop & implement tools for reducing gaps in screening for immunotherapies w/..risk of TB” www.infectiousdiseaseadvisor.com/news/tubercu...
“Although vaccination is often deferred until partial immune recovery, patients with the lowest CD4+ counts face the greatest infection risk, raising concern that deferral may leave them vulnerable during a period of peak susceptibility.” www.infectiousdiseaseadvisor.com/news/low-cd4...
Low CD4+ Count Increases CAP and Herpes Zoster Risk in Patients With HIV
Persistent CAP and HZ risks remain for patients with HIV who have low CD4+ counts or limited ART exposure, despite general population trends.
www.infectiousdiseaseadvisor.com
January 26, 2026 at 12:59 PM
“Although vaccination is often deferred until partial immune recovery, patients with the lowest CD4+ counts face the greatest infection risk, raising concern that deferral may leave them vulnerable during a period of peak susceptibility.” www.infectiousdiseaseadvisor.com/news/low-cd4...
"At a time when unprecedented changes to the federal vaccine schedule threaten decades of scientific progress, the AMA strongly supports the AAP's childhood and adolescent immunization schedule to keep children safe and healthy." www.medpagetoday.com/pediatrics/v...
AAP Releases 2026 Child Vax Schedule, No Longer Endorses CDC's Version
'We're going to publish vaccine recommendations that are based on scientific evidence'
www.medpagetoday.com
January 26, 2026 at 12:58 PM
"At a time when unprecedented changes to the federal vaccine schedule threaten decades of scientific progress, the AMA strongly supports the AAP's childhood and adolescent immunization schedule to keep children safe and healthy." www.medpagetoday.com/pediatrics/v...
“For now, unfortunately, we have to ignore everything about vaccines that is coming from our federal government,” www.cnn.com/2026/01/26/h...
Doctors are ignoring new federal vaccine recommendations | CNN
The American Academy of Pediatrics on Monday released its updated recommendations for what vaccines children should get. It’s a routine revision, hardly different from last year’s recommendations, but...
www.cnn.com
January 26, 2026 at 12:56 PM
“For now, unfortunately, we have to ignore everything about vaccines that is coming from our federal government,” www.cnn.com/2026/01/26/h...
“It’s clear that what’s coming from the federal government is not grounded in science, but rather in ideology, and so we are continuing to make our recommendations based on what’s in the best interest of children” www.wsj.com/health/healt...
Defying CDC, Pediatricians Recommend All Kids Get Vaccinations Against 18 Diseases
The American Academy of Pediatrics’ recommendations for hepatitis B, influenza and other shots buck changes made by the Trump administration.
www.wsj.com
January 26, 2026 at 12:55 PM
“It’s clear that what’s coming from the federal government is not grounded in science, but rather in ideology, and so we are continuing to make our recommendations based on what’s in the best interest of children” www.wsj.com/health/healt...
“I realize that we’re dealing with people who are in a different reality. They don’t understand public health. They don’t understand what it was like to encounter the dangers of the past.” www.statnews.com/2026/01/25/w...
Public health giant William Foege, who helped eradicate smallpox, has died at 89
‘I wish we could have spared him from seeing that’: Friends of Bill Foege on his legacy, and his anger over anti-vaccination.
www.statnews.com
January 26, 2026 at 12:14 PM
“I realize that we’re dealing with people who are in a different reality. They don’t understand public health. They don’t understand what it was like to encounter the dangers of the past.” www.statnews.com/2026/01/25/w...
In this video I discuss one of the most common infectious disease diagnostic tests: blood cultures
January 25, 2026 at 6:37 PM
In this video I discuss one of the most common infectious disease diagnostic tests: blood cultures
“The first and most important rule is to know the truth. You have to set up a surveillance system to know the truth, otherwise you’re responding blindly. The truth changes every day in the White House.”
www.nytimes.com/2026/01/24/u...
www.nytimes.com/2026/01/24/u...
William H. Foege, Key Figure in the Eradication of Smallpox, Dies at 89
www.nytimes.com
January 25, 2026 at 6:33 AM
“The first and most important rule is to know the truth. You have to set up a surveillance system to know the truth, otherwise you’re responding blindly. The truth changes every day in the White House.”
www.nytimes.com/2026/01/24/u...
www.nytimes.com/2026/01/24/u...
In this video I discuss the Oscar nominated movie *The Ugly Stepsister* and its tapeworm subplot
January 24, 2026 at 10:20 PM
In this video I discuss the Oscar nominated movie *The Ugly Stepsister* and its tapeworm subplot
In this piece I am quoted about the role of vitamin D in respiratory infections www.prevention.com/health/healt...
Scientists Find Common Supplement May Help Protect Against the Flu
Here’s what doctors have to say.
www.prevention.com
January 24, 2026 at 7:10 PM
In this piece I am quoted about the role of vitamin D in respiratory infections www.prevention.com/health/healt...
“A W.H.O. meeting on next year’s vaccine is scheduled for February. The official said the Trump administration would soon disclose how or whether it will participate.”
www.nytimes.com/2026/01/22/u...
www.nytimes.com/2026/01/22/u...
U.S. Formally Withdraws From World Health Organization
www.nytimes.com
January 24, 2026 at 12:50 PM
“A W.H.O. meeting on next year’s vaccine is scheduled for February. The official said the Trump administration would soon disclose how or whether it will participate.”
www.nytimes.com/2026/01/22/u...
www.nytimes.com/2026/01/22/u...
In this video I discuss why I chose infectious disease as a career. Short answer — it’s the puzzles, the detective work, the integration with everything in the world. youtu.be/kLrl3FcfaeU?...
The Puzzle That Made Me Choose Infectious Disease
YouTube video by Amesh Adalja MD
youtu.be
January 24, 2026 at 12:32 PM
In this video I discuss why I chose infectious disease as a career. Short answer — it’s the puzzles, the detective work, the integration with everything in the world. youtu.be/kLrl3FcfaeU?...
In this video I discuss locally acquired Chikungunya and the promise of GMO mosquitos
January 24, 2026 at 4:05 AM
In this video I discuss locally acquired Chikungunya and the promise of GMO mosquitos
“I believe he went against some of his own beliefs as a physician” — exactly and that concretizes how he lusts for political power more than objectivity, logic, reason, and the truth www.nytimes.com/2026/01/23/u...
A Republican Vaccine Defender Fights to Hang On
www.nytimes.com
January 24, 2026 at 2:40 AM
“I believe he went against some of his own beliefs as a physician” — exactly and that concretizes how he lusts for political power more than objectivity, logic, reason, and the truth www.nytimes.com/2026/01/23/u...
“He has no idea what he’s talking about,” www.nytimes.com/2026/01/23/h...
Rejecting Decades of Science, Vaccine Panel Chair Says Polio and Other Shots Should Be Optional
www.nytimes.com
January 24, 2026 at 2:36 AM
“He has no idea what he’s talking about,” www.nytimes.com/2026/01/23/h...
“AMR is undermining our ability to treat even routine infections, putting millions of lives at risk, especially in lower- and middle-income countries," www.cidrap.umn.edu/antimicrobia...
Philanthropic groups announce $60 million in grants for antibiotic discovery
The money from the Gates Foundation, Novo Nordisk Foundation, and Wellcome has been awarded to researchers in 17 countries.
www.cidrap.umn.edu
January 23, 2026 at 10:44 PM
“AMR is undermining our ability to treat even routine infections, putting millions of lives at risk, especially in lower- and middle-income countries," www.cidrap.umn.edu/antimicrobia...
“Crestone evaluated the safety and efficacy of the company’s CRS3123, a small-molecule protein synthesis inhibitor that targets an enzyme found in C difficile and a few species of gut bacteria” www.cidrap.umn.edu/clostridium-...
Narrow-spectrum C difficile antibiotic shows promise in phase 2 study
A small-molecule protein synthesis inhibitor that targets C diff without disrupting the gut microbiome was found to be highly effective and well-tolerated in a small randomized trial.
www.cidrap.umn.edu
January 23, 2026 at 10:43 PM
“Crestone evaluated the safety and efficacy of the company’s CRS3123, a small-molecule protein synthesis inhibitor that targets an enzyme found in C difficile and a few species of gut bacteria” www.cidrap.umn.edu/clostridium-...
“While 48% to 57% of hospitalized children received antivirals for flu before the pandemic, a team led by researchers..found that 38% of these kids received the medications in 2021 to 2022, along with 46% in 2022 to 2023” www.cidrap.umn.edu/influenza-ge...
Antiviral use in kids with flu dropped during pandemic
The use of antiviral treatments in children hospitalized for influenza fell sharply during the COVID-19 pandemic, according to a study in Pediatrics.
www.cidrap.umn.edu
January 23, 2026 at 10:38 PM
“While 48% to 57% of hospitalized children received antivirals for flu before the pandemic, a team led by researchers..found that 38% of these kids received the medications in 2021 to 2022, along with 46% in 2022 to 2023” www.cidrap.umn.edu/influenza-ge...
“While seasonal flu activity in the US has decreased for 3 consecutive weeks & hospitalizations among school-aged children are stable, flu activity remains elevated nationally & influenza-related emergency department visits for school-aged children are increasing” www.cidrap.umn.edu/influenza-ge...
US flu activity declines for 3rd straight week but remains elevated
www.cidrap.umn.edu
January 23, 2026 at 10:36 PM
“While seasonal flu activity in the US has decreased for 3 consecutive weeks & hospitalizations among school-aged children are stable, flu activity remains elevated nationally & influenza-related emergency department visits for school-aged children are increasing” www.cidrap.umn.edu/influenza-ge...
“Mounting safety evidence as feds dismantle vaccine schedule” www.cidrap.umn.edu/childhood-va...
No link found between routine childhood vaccines, aluminum adjuvants, and epilepsy risk
www.cidrap.umn.edu
January 23, 2026 at 10:31 PM
“Mounting safety evidence as feds dismantle vaccine schedule” www.cidrap.umn.edu/childhood-va...
“The DPH identified new public exposures at 5 elementary schools, &15 other schools already had students in quarantine. The agency also highlighted public exposures at stores, a fitness center, & a post office in Boiling Springs, Greer, Duncan, & Gaffney” www.cidrap.umn.edu/measles/sout...
South Carolina’s measles outbreak hits 700 cases as CDC confirms 416 so far in 2026
www.cidrap.umn.edu
January 23, 2026 at 10:29 PM
“The DPH identified new public exposures at 5 elementary schools, &15 other schools already had students in quarantine. The agency also highlighted public exposures at stores, a fitness center, & a post office in Boiling Springs, Greer, Duncan, & Gaffney” www.cidrap.umn.edu/measles/sout...
Part of his calculated methodical attack on the entire vaccine ecosystem in the US www.statnews.com/2026/01/23/k...
Key autism committee is being reshaped to support Kennedy's vaccine agenda, researchers and advocates fear
Researchers and advocates fear a key autism committee is being reshaped to support Kennedy's vaccine agenda.
www.statnews.com
January 23, 2026 at 9:21 PM
Part of his calculated methodical attack on the entire vaccine ecosystem in the US www.statnews.com/2026/01/23/k...