AndexerLab
@andexerlab.bsky.social
Interested in cofactor-dependent enzymes, cofactor analogues and cofactor regeneration systems. https://www.pharmazeutische-chemie.uni-freiburg.de/de/andexer
Thanks to all co-workers, this was a great team effort and an important part in the preparation process of @for5596.bsky.social - now happy to see the ChemBioChem view statistics.
Congratulations to all the authors of this paper, which just ranked in the top 10% of the most viewed papers published in ChemBioChem in 2023! We are very excited to be able to build on this amazing work in our FOR5596 research group.
@andexerlab.bsky.social @rentmeisterlab.bsky.social
@andexerlab.bsky.social @rentmeisterlab.bsky.social
Biomimetic S‐Adenosylmethionine Regeneration Starting from Multiple Byproducts Enables Biocatalytic Alkylation with Radical SAM Enzymes**
The biomimetic regeneration system for S-adenosylmethionine (SAM) and SAM analogues presented is based on the salvage of the adenine moiety and in situ supply of d-ribose and polyphosphate. It is com...
chemistry-europe.onlinelibrary.wiley.com
April 17, 2025 at 8:52 AM
Thanks to all co-workers, this was a great team effort and an important part in the preparation process of @for5596.bsky.social - now happy to see the ChemBioChem view statistics.
If you want to know how to tell an N from an O, you can get some ideas in our new paper. This was a great team effort, introducing us to new methods: MD w/ Ferran Feixas & Marc Garcia Borràs (Girona) + HDX-MS w/ Wieland Steinchen & Gert Bange @bangebalcony.bsky.social
pubs.acs.org/doi/10.1021/...
pubs.acs.org/doi/10.1021/...
How to Tell an N from an O: Controlling the Chemoselectivity of Methyltransferases
S-Adenosyl-l-methionine (SAM)-dependent methyltransferases (MTs) are important enzymes in numerous biological pathways. They share a common SN2 mechanism but act on different nucleophilic substrates i...
pubs.acs.org
April 4, 2025 at 3:36 PM
If you want to know how to tell an N from an O, you can get some ideas in our new paper. This was a great team effort, introducing us to new methods: MD w/ Ferran Feixas & Marc Garcia Borràs (Girona) + HDX-MS w/ Wieland Steinchen & Gert Bange @bangebalcony.bsky.social
pubs.acs.org/doi/10.1021/...
pubs.acs.org/doi/10.1021/...
Reposted by AndexerLab
FOR 5596 is now on BlueSky! Follow us to stay informed about our collaborative project "Unfolding the potential of SAM-dependent enzyme chemistry".
April 2, 2025 at 2:20 PM
FOR 5596 is now on BlueSky! Follow us to stay informed about our collaborative project "Unfolding the potential of SAM-dependent enzyme chemistry".
Reposted by AndexerLab
Noch bis zum 24.3. Zeit den Appell für mehr Klimaschutz in den Koalitionsverhandlungen zu unterschreiben.
www.bayceer.uni-bayreuth.de/s4f/de/top/o...
www.bayceer.uni-bayreuth.de/s4f/de/top/o...
March 13, 2025 at 7:32 PM
Noch bis zum 24.3. Zeit den Appell für mehr Klimaschutz in den Koalitionsverhandlungen zu unterschreiben.
www.bayceer.uni-bayreuth.de/s4f/de/top/o...
www.bayceer.uni-bayreuth.de/s4f/de/top/o...
🖍️ We are happy to share our latest paper! Introduction of the formate assimilation from M. extorquens into E. coli allows transformation of formate into methyl groups. Renewable C1 compounds for biocatalytic methylation!
microbialcellfactories.biomedcentral.com/articles/10....
microbialcellfactories.biomedcentral.com/articles/10....
Rewiring Escherichia coli to transform formate into methyl groups - Microbial Cell Factories
Background Biotechnological applications are steadily growing and have become an important tool to reinvent the synthesis of chemicals and pharmaceuticals for lower dependence on fossil resources. In ...
microbialcellfactories.biomedcentral.com
March 13, 2025 at 3:55 PM
🖍️ We are happy to share our latest paper! Introduction of the formate assimilation from M. extorquens into E. coli allows transformation of formate into methyl groups. Renewable C1 compounds for biocatalytic methylation!
microbialcellfactories.biomedcentral.com/articles/10....
microbialcellfactories.biomedcentral.com/articles/10....