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Andrew Pines

@andrewpines.bsky.social

420 followers 290 following 81 posts

Postdoctoral Research Fellow at Brigham and Women’s Hospital. Interested in psychosis, causality, neuroimaging, neuromodulation

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Andrew Pines @andrewpines.bsky.social · Feb 12

jamanetwork.com/journals/jam...
Thread below👇

Mapping Lesions That Cause Psychosis

This case-control study analyzes published cases of lesion-induced psychosisTo assess whether lesions that cause secondary psychosis have functional connections to a common brain circuit

jamanetwork.com

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Reposted by Andrew Pines

Andreas Horn @andreashorn.org · Aug 22

🚨 New preprint out! 🚨
“Translating the Transcriptome: A Connectomics Approach for Gene-Network Mapping and Clinical Application”
🔗 doi.org/10.1101/2025...

🧵 A short thread:

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Reposted by Andrew Pines

Thomas Yeo @bttyeo.bsky.social · Jul 17

1/11 Excited to share our @Naturestudy led by @leonooi.bsky.social @csabaorban.bsky.social @shaoshiz.bsky.social

AI performance is known to scale with logarithm of sample size (Kaplan 2020), but in many domains, sample size can be # participants or # measurements...

doi.org/10.1038/s415...

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Reposted by Andrew Pines

Damien Fair @drdamienfair.bsky.social · Jun 26

Alert!!!!

“An Action Networks Model for Pain”

We propose a new model for chronic pain — and highlight two functionally connected cortical networks that could revolutionize how we treat it.

👉 thread below 🧵

osf.io/preprints/ps...

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Reposted by Andrew Pines

Alexander Li Cohen @drdrxanderli.bsky.social · Jun 17

Thrilled our ADHD network mapping work is now out in Annals of the Child Neurology Society, and honored to be featured on the cover!
🔗 Full article: onlinelibrary.wiley.com/doi/full/10....

@childneurosoc.bsky.social @bostonchildrens.bsky.social @simonwarfield.bsky.social @braincircuits.bsky.social

Coordinate Network Mapping of Focal Brain Volume Differences in ADHD Reveals Common Patterns That Lack Specificity: A Systematic Review

Objective Attention-deficit/hyperactivity disorder (ADHD) has been associated with decreased regional brain volume, yet no consistent localization has emerged across studies. This discrepancy has be...

onlinelibrary.wiley.com

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Reposted by Andrew Pines

Shan Siddiqi @shansiddiqi.bsky.social · Mar 23

Out now in Brain

A distinct pattern of brain damage intensifies political involvement, regardless of whether you're liberal, conservative, Democrat, or Republican.

With coauthors S.Balters,S. Cohen-Zimerman,G.Zamboni,J.Grafman

academic.oup.com/brain/advanc...

@braincircuits.bsky.social

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Reposted by Andrew Pines

Awais Aftab @awaisaftab.bsky.social · May 23

Mixed Bag #22: Nils Wendel on Learning Psychopharmacology

Wendel explores the topic using a book, a concept, a person, an article, and a surprise item

www.psychiatrymargins.com/p/mixed-bag-...

Mixed Bag #22: Nils Wendel on Learning Psychopharmacology

A book, a concept, a person, an article, and a surprise item

www.psychiatrymargins.com

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Reposted by Andrew Pines

Andreas Horn @andreashorn.org · May 14

MR guided focused ultrasound surgery is an effective and uprising treatment option for Essential tremor. But where is the optimal site to sonicate? Which spots to avoid due to side-effects?

@science.org @braincircuits.bsky.social @netstim.org

– a thread🧵!

www.science.org/doi/10.1126/...

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Reposted by Andrew Pines

The Transmitter @thetransmitter.bsky.social · May 16

The brainstem’s red nucleus is an evolutionarily old structure that emerged as animals began to use limbs for walking, but its function in humans reaches beyond motor control, a new study suggests.

By @sydneywyatt.bsky.social

#neuroskyence

www.thetransmitter.org/brain-imagin...

‘Old’ brainstem structure evolved beyond basic motor control

The human red nucleus may also help coordinate action, reward and motivated behavior, a new study suggests.

www.thetransmitter.org

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Andrew Pines @andrewpines.bsky.social · May 15

Rightfully so!

Reposted by Andrew Pines

Andreas Horn @andreashorn.org · May 12

When modeling volumes of tissue activated in subthalamic DBS for clinical outcomes, does it matter whether we process data in native or template space? Julianna Pijar and Clemens Neudorfer say No in the Brain Stimulation Journal:
doi.org/10.1016/j.br...

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Reposted by Andrew Pines

Sidhant Chopra @sidchop.bsky.social · May 12

🧠💊New preprint differentiating antipsychotic medication vs. illness effects on cortical thickness in people w/ psychosis.

Finding: People receiving placebo show prominent cortical thinning over 1st year of illness, whereas those receiving antipsychotics do not. 1/3

www.medrxiv.org/content/10.1...

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Reposted by Andrew Pines

Sheila Shanmugan @sheilashanmugan.bsky.social · Apr 28

We’re hiring a clinical research coordinator to lead a neuroimaging study on brain changes across pregnancy and perinatal depression.

wd1.myworkdaysite.com/en-US/recrui...

Please RT.

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Reposted by Andrew Pines

Stimulating Brains @stimulatingbrains.org · Apr 25

It was a great honor to talk with the founding editor of Brain Stimulation, Dr. Harold Sackeim!
Beyond the past, present and future of ECT, we covered the entire field of neuromodulation.

Priceless insights from a key leader in the field!

Tune in here 👇

stimulatingbrains.org/71-harold-sa...

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Andrew Pines @andrewpines.bsky.social · Apr 23

Really interesting thread and super cool work!

Reposted by Andrew Pines

Stimulating Brains @stimulatingbrains.org · Apr 22

We had a truly inspiring and insightful conversation with Dr. Rees Cosgrove, Director of Epilepsy and Functional Neurosurgery at @brighamandwomens.bsky.social & Professor of Neurosurgery @harvardmed.bsky.social

Rediscovering the lost art of brain lesions…!

stimulatingbrains.org/70-rees-cosg...

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Reposted by Andrew Pines

Sam Gershman @gershbrain.bsky.social · Apr 16

A postdoc in my lab contacted a fellow scientist to get some advice and was told that, because he's currently working on the topic, he "can't give away all his secrets." I find this extremely lame, and yet I keep encountering it. Science is not a zero-sum game!!

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Andrew Pines @andrewpines.bsky.social · Apr 16

This was a hard one to click the ‘like’ button on. You will be missed!

Reposted by Andrew Pines

Andreas Horn @andreashorn.org · Apr 16

Probably the most insightful and most important paper on physiomarkers of subthalamic DBS in a long while. Bravo @julianneumann.bsky.social @tsbinns.com and team!!

Out at @natcomms.nature.com:
www.nature.com/articles/s41...

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Reposted by Andrew Pines

Precision Neurotherapeutics Lab @ Stanford @stanfordpntlab.bsky.social · Apr 9

When we use TMS to treat depression, we think it alters neural activity in a deep brain structure known as the subgenual anterior cingulate (sgACC). But this is hard to test directly, until our preprint with @coreykeller.bsky.social, @neuro-engineer.bsky.social, Nick Trapp, and Aaron Boes (UIowa) 1/

DLPFC Stimulation Suppresses High-Frequency Neural Activity in the Human sgACC

Transcranial magnetic stimulation (TMS) to the dorsolateral prefrontal cortex (DLPFC) is hypothesized to relieve symptoms of depression by inhibiting activity in the subgenual anterior cingulate corte...

www.biorxiv.org

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Reposted by Andrew Pines

Thomas Yeo @bttyeo.bsky.social · Mar 26

It's finally here! Use the Network Correspondence Toolbox to help contextualize your neuroimaging findings 🧠

A network correspondence toolbox for quantitative evaluation of novel neuroimaging results - Nature Communications

Here, the authors present the Network Correspondence Toolbox, which enables researchers to examine and report spatial correspondence between their neuroimaging results and widely used brain atlases.

www.nature.com

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Reposted by Andrew Pines

Isaiah Kletenik @isaiahneuro.bsky.social · Mar 26

Cool talk by Aaron Boes on clinical applications and cognitive prognosis from network neuroimaging @bostonchildrens.bsky.social @harvardmed.bsky.social

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Andrew Pines @andrewpines.bsky.social · Mar 23

Started my morning with a super interesting literature search thanks to this prompt!
Were currently analyzing volumetric changes pre and post ECT in schizophrenia - will be really cool to compare seizures that cause psychosis to seizures that improve psychosis. Really admire your work, by the way

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Reposted by Andrew Pines

Audrey Luo @audreycluo.bsky.social · Mar 20

We think of white matter as the brain's highways—uniform conduits between cortices. But what if we study development along tracts? Turns out the journey matters as much as the cortical destination! We're thrilled to share “Two Axes of White Matter Development” www.biorxiv.org/content/10.1...
1/n

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Reposted by Andrew Pines

Can Sarica @cansarica.bsky.social · Mar 22

Proud to share the first of our two-part sequel papers on the #TUS-#DBS project! t.co/yrGRcdpjXn
We recorded local field potentials using #PerceptPc #DBS systems in #Parkinsons patients while applying transcranial ultrasound stimulation (#TUS) — aiming to better understand its effects & mechanisms.

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Reposted by Andrew Pines

Andreas Horn @andreashorn.org · Mar 21

Interested in an update on connectomic and adaptive deep brain stimulation for obsessive compulsive disorder?

Take a look at our summary of this exciting field and how things could be brought together out now in BPS:

www.biologicalpsychiatryjournal.com/article/S000...

A brief 🧵

Deep Brain Stimulation response circuits in Obsessive Compulsive Disorder

In the field of deep brain stimulation (DBS), two major themes are currently making significant progress. First, the framework of connectomic DBS, in which circuits that are associated with improvemen...

www.biologicalpsychiatryjournal.com

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