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andrologyj.bsky.social
@andrologyj.bsky.social
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🐀 New in Andrology:

Lycium barbarum polysaccharides (LBP) restore spermatogenesis in aging rats by rebalancing calcium signaling.

LBP improved testicular structure, boosted spermatogonia, normalized sex hormone levels, and reduced oxidative stress and apoptosis.

Read more doi.org/10.1111/andr...
🔍 Findings:
PS-MPs (8 µm) stay outside but trigger inflammation
PS-NPs (80 nm) slip inside cells, causing stronger oxidative stress and apoptosis

💡 Takeaway: As environmental plastics break down into ever-smaller particles, their hidden risks to male fertility become more severe.
Microplastics vs. Nanoplastics – A closer look at male fertility risks

New research compares polystyrene microplastics (PS-MPs) and nanoplastics (PS-NPs) in rat Sertoli cells, the key guardians of sperm development.
⚡ How do sperm find the right “gear” for fertilization?

New research reveals that lactate shifts bull sperm from zigzag motility to straight-line movement by suppressing glycolysis and boosting oxidative metabolism. 🚀
📡 Can prolonged exposure to 35.5 GHz millimeter waves, like those used in modern wireless tech, affect male fertility?

This study shows chronic exposure in rats led to oxidative stress, DNA damage, and impaired sperm quality, pointing to potential risks for testicular health.
✨ Infertility in the Bible?

A new article looks at the Genetics of infertility and “assisted fertilization” in the Bible. It focuses on Abraham, Isaac and Jacob, whose wives all faced infertility.
🧬 Why are some testicular tumours so hard to predict and treat?

New research uses spatial transcriptomics to map immune cell activity and TGFβ signaling in testicular germ cell tumours.
💤⚡ Can sleepless nights harm sexual health?

New research in Andrology reveals how men with anejaculation, with and without sleep disorders, show striking brain differences on fMRI.
Using at-home semen tests, researchers found that lower sperm concentration, total count, and motile sperm count were all linked to reduced chances of conception per cycle.

🧬 Real-world data. Clinically relevant thresholds. Insightful takeaways for reproductive health.
📉 Does semen quality predict time to pregnancy?

A new prospective study published in Andrology examines semen parameters and fecundability in over 700 North American couples trying to conceive.
🚨 LH and FSH may come from the same cell – but they follow very different paths.

This new review traces the evolution and trafficking of gonadotropins from primitive fish to mammals, revealing how molecular tweaks to FSH secretion can boost ovulation and ovarian health.
New clues in the quest to predict male fertility in boars 🐖💡

Proteomic profiling of pig seminal extracellular vesicles reveals dozens of proteins linked to sperm function, embryo development, and implantation. These biomarkers could improve boar selection in AI programs.
🧊 Freezing damages more than you think.

🔍 A new study in Andrology reveals how slow freezing reshapes sperm chromatin deep inside the nucleus.

This tool could be a game-changer for assessing sperm quality in fertility clinics.
This work highlights a concerning link between associated hypospadias and higher perinatal mortality.

🧬 These findings underscore the urgent need for further clinical and epidemiological research into causes and prevention.

👉 Read the full study: doi.org/10.1111/andr...
Epidemiology of hypospadias in China: A nationwide surveillance‐based study, 2010–2020
Background The prevalence of hypospadias varied internationally. However, epidemiological data on hypospadias in contemporary China remain limited. Objectives We aim to examine the epidemiological.....
doi.org
A new nationwide study published in Andrology reveals that the prevalence of hypospadias has significantly increased in China between 2010 and 2020.

🔍 Using data from over 11 million births, the research uncovers geographic and demographic disparities.