Angus Bucknell
@angusb.bsky.social
PhD candidate in the @talbotlabtsl.bsky.social group. Focusing on protein design and effector biology in Magnaporthe oryzae.
www.ahbucknell.com
www.ahbucknell.com
Reposted by Angus Bucknell
So happy to have @mcdonaldmeganc.bsky.social with us for the day!
Our @TheSainsburyLab postdoc invited speaker is Megan McDonald @McdonaldMeganc — jumping genes and pathogenic schemes.
Prof. Megan will be joining @ETH_en in 2026!!!! 🎉 🥳 👏🏼 #planthealth #plantpath ethz.ch/en/news-and-...
Prof. Megan will be joining @ETH_en in 2026!!!! 🎉 🥳 👏🏼 #planthealth #plantpath ethz.ch/en/news-and-...
October 2, 2025 at 12:41 PM
So happy to have @mcdonaldmeganc.bsky.social with us for the day!
Delighted that our work on the Sanctuary Starship #transposon is now published! A big thanks to all co-authors, especially to the ever-amazing @mcdonaldmeganc.bsky.social for her mentorship!
doi.org/10.1128/mbio...
doi.org/10.1128/mbio...
Sanctuary: a Starship transposon facilitating the movement of the virulence factor ToxA in fungal wheat pathogens | mBio
The work presented here expands our understanding of a novel group of mobile genetic
elements called Starships that facilitate the horizontal exchange of numerous genes between fungal pathogens.
Our a...
doi.org
September 6, 2025 at 1:11 PM
Delighted that our work on the Sanctuary Starship #transposon is now published! A big thanks to all co-authors, especially to the ever-amazing @mcdonaldmeganc.bsky.social for her mentorship!
doi.org/10.1128/mbio...
doi.org/10.1128/mbio...
Reposted by Angus Bucknell
I talk a lot about Rust for building high-perf (& even non-perf critical) software, & scientific software in particular. I often discuss what's interesting to me, but wanted to offer the chance to those interested for me to answer their questions about Rust in science. Fire away with questions!🧬🖥️
August 3, 2025 at 6:12 PM
I talk a lot about Rust for building high-perf (& even non-perf critical) software, & scientific software in particular. I often discuss what's interesting to me, but wanted to offer the chance to those interested for me to answer their questions about Rust in science. Fire away with questions!🧬🖥️
Reposted by Angus Bucknell
You designed binders for your favourite protein and wish there was a way to experimentally screen them within 24h w/ only a set of pipettes and a plate reader?
Check out our Cell-Free 2-Hybrid approach (CF2H)
Full post: tinyurl.com/48cz5nb6
Preprint: www.biorxiv.org/cgi/content/...
Check out our Cell-Free 2-Hybrid approach (CF2H)
Full post: tinyurl.com/48cz5nb6
Preprint: www.biorxiv.org/cgi/content/...
July 17, 2025 at 11:42 AM
You designed binders for your favourite protein and wish there was a way to experimentally screen them within 24h w/ only a set of pipettes and a plate reader?
Check out our Cell-Free 2-Hybrid approach (CF2H)
Full post: tinyurl.com/48cz5nb6
Preprint: www.biorxiv.org/cgi/content/...
Check out our Cell-Free 2-Hybrid approach (CF2H)
Full post: tinyurl.com/48cz5nb6
Preprint: www.biorxiv.org/cgi/content/...
Reposted by Angus Bucknell
#2025ISMPMI Agnus Bucknell of the Talbot lab gives an exciting presentation to engineer fungal effectors recognizing immune sensors based on Pik1. Great and clear talk.
July 17, 2025 at 8:58 AM
#2025ISMPMI Agnus Bucknell of the Talbot lab gives an exciting presentation to engineer fungal effectors recognizing immune sensors based on Pik1. Great and clear talk.
Reposted by Angus Bucknell
#2025ISMPMI Want to know about transcriptional regulation driving pathogenicity in the blast fungus? Come to my poster (P-156) session today!
From 13:30 to 15:15 🌾
From 13:30 to 15:15 🌾
July 17, 2025 at 7:27 AM
#2025ISMPMI Want to know about transcriptional regulation driving pathogenicity in the blast fungus? Come to my poster (P-156) session today!
From 13:30 to 15:15 🌾
From 13:30 to 15:15 🌾
Reposted by Angus Bucknell
@angusb.bsky.social wants to engineer plant resistance proteins (NLRs) from scratch.
Can we create protein domains to integrate into NLRs to catch pathogen effectors? New tech makes this possible now.
Chose Magnaporthe and Fusarium effectors as targets - many steps later, it worked!
#2025ISMPMI
Can we create protein domains to integrate into NLRs to catch pathogen effectors? New tech makes this possible now.
Chose Magnaporthe and Fusarium effectors as targets - many steps later, it worked!
#2025ISMPMI
July 17, 2025 at 9:04 AM
@angusb.bsky.social wants to engineer plant resistance proteins (NLRs) from scratch.
Can we create protein domains to integrate into NLRs to catch pathogen effectors? New tech makes this possible now.
Chose Magnaporthe and Fusarium effectors as targets - many steps later, it worked!
#2025ISMPMI
Can we create protein domains to integrate into NLRs to catch pathogen effectors? New tech makes this possible now.
Chose Magnaporthe and Fusarium effectors as targets - many steps later, it worked!
#2025ISMPMI
Reposted by Angus Bucknell
@mcdonaldmeganc.bsky.social presents on the ToxB fungal effector. Pacbio long-read sequencing ~doubles detection of transposons compared to short-read. Helpful for finding where the multiple copies of ToxB -flanked by TEs- are throughout the genome. Sometimes in tandem copies! #2025ISMPMI
July 14, 2025 at 9:01 AM
@mcdonaldmeganc.bsky.social presents on the ToxB fungal effector. Pacbio long-read sequencing ~doubles detection of transposons compared to short-read. Helpful for finding where the multiple copies of ToxB -flanked by TEs- are throughout the genome. Sometimes in tandem copies! #2025ISMPMI
Reposted by Angus Bucknell
Excited to attend my 1st ISMPMI conference, and present our work on a paired wheat CNL/MLKL receptor mechanism! 🌾
Come chat to me at my poster on Tuesday, P-050! 📜
If you miss my poster session, I will be talking in: Crop resistance genetics and genomics on Wednesday - 16:25-16:35!
Come chat to me at my poster on Tuesday, P-050! 📜
If you miss my poster session, I will be talking in: Crop resistance genetics and genomics on Wednesday - 16:25-16:35!
July 14, 2025 at 5:07 PM
Excited to attend my 1st ISMPMI conference, and present our work on a paired wheat CNL/MLKL receptor mechanism! 🌾
Come chat to me at my poster on Tuesday, P-050! 📜
If you miss my poster session, I will be talking in: Crop resistance genetics and genomics on Wednesday - 16:25-16:35!
Come chat to me at my poster on Tuesday, P-050! 📜
If you miss my poster session, I will be talking in: Crop resistance genetics and genomics on Wednesday - 16:25-16:35!
Big thanks to everyone who stopped by my poster today at #2025ISMPMI!
For those that missed it, you can check it out on Zenodo!
zenodo.org/records/1588...
For those that missed it, you can check it out on Zenodo!
zenodo.org/records/1588...
Engineering new-to-nature immune sensors for novel recognition of Magnaporthe oryzae
Phytopathogenic fungi significantly impact global food security, causing up to 40% of annual crop yield losses worldwide. Alone, the blast fungus Magnaporthe oryzae has a global economic impact of $66...
zenodo.org
July 14, 2025 at 3:42 PM
Big thanks to everyone who stopped by my poster today at #2025ISMPMI!
For those that missed it, you can check it out on Zenodo!
zenodo.org/records/1588...
For those that missed it, you can check it out on Zenodo!
zenodo.org/records/1588...
Looking forward to #2025ISMPMI next week! I'll be presenting during the Engineering Plant-Microbe Traits session on Thursday, 17th.
I'll be sharing some exciting collaborative work which will also be showcased by me at P-427 (Session 1, 14th) and Yuxuan Xi at P-193 (Session 2, 16th)! Come say hi!
I'll be sharing some exciting collaborative work which will also be showcased by me at P-427 (Session 1, 14th) and Yuxuan Xi at P-193 (Session 2, 16th)! Come say hi!
July 9, 2025 at 12:02 PM
Looking forward to #2025ISMPMI next week! I'll be presenting during the Engineering Plant-Microbe Traits session on Thursday, 17th.
I'll be sharing some exciting collaborative work which will also be showcased by me at P-427 (Session 1, 14th) and Yuxuan Xi at P-193 (Session 2, 16th)! Come say hi!
I'll be sharing some exciting collaborative work which will also be showcased by me at P-427 (Session 1, 14th) and Yuxuan Xi at P-193 (Session 2, 16th)! Come say hi!
Happy to have been featured in the Robigalia newsletter, led by @myrtlerustmartino.bsky.social. I would highly recommend checking out the newsletter for weekly plant pathology news and jobs/scholarships!
robigalia.beehiiv.com/p/robigalia-...
robigalia.beehiiv.com/p/robigalia-...
Robigalia Roundup #28
Photosynthetic performance of infected eucalypt clones, and meet Angus Bucknell
robigalia.beehiiv.com
April 29, 2025 at 5:36 PM
Happy to have been featured in the Robigalia newsletter, led by @myrtlerustmartino.bsky.social. I would highly recommend checking out the newsletter for weekly plant pathology news and jobs/scholarships!
robigalia.beehiiv.com/p/robigalia-...
robigalia.beehiiv.com/p/robigalia-...
Reposted by Angus Bucknell
We did it! We caught Starship #transposons moving between #fungal species in the lab, including between species separated by ~100my. We think Starships are a mediator of HGT in fungi, akin to conjugative elements in bacteria. Check out the preprint. www.biorxiv.org/content/10.1...
March 7, 2025 at 7:18 AM
We did it! We caught Starship #transposons moving between #fungal species in the lab, including between species separated by ~100my. We think Starships are a mediator of HGT in fungi, akin to conjugative elements in bacteria. Check out the preprint. www.biorxiv.org/content/10.1...
Opportunities to do some great science with a great supervisor!
Having worked in Megan’s lab for my Master’s research I can personally attest to how great of a PI she is!
Having worked in Megan’s lab for my Master’s research I can personally attest to how great of a PI she is!
HI old friends! Finally took the leap here to say I have several open positions going in my lab at the moment (and more to come).
1) PhD studentship in collaboration with the Royal Horticultural Society (genomics)
2) Biochemistry Postdoc to understand how Starships move
Check out the links below!
1) PhD studentship in collaboration with the Royal Horticultural Society (genomics)
2) Biochemistry Postdoc to understand how Starships move
Check out the links below!
December 8, 2024 at 10:34 PM
Opportunities to do some great science with a great supervisor!
Having worked in Megan’s lab for my Master’s research I can personally attest to how great of a PI she is!
Having worked in Megan’s lab for my Master’s research I can personally attest to how great of a PI she is!
Reposted by Angus Bucknell
If you're from the UK and are looking for a PhD, don't miss out on this fantastic opportunity! Amazing lab and amazing project!
📢 PhD Opportunity in my lab on Plant Immune Receptor Bioengineering at @imperiallifesci.bsky.social
🌱 Start: October 2025
📅 Deadline: 12th January 2025
🇬🇧 Open to UK students
💰 Fully funded
ℹ️ More info: tinyurl.com/w6ap9v9f
❗ #PlantImmunity #PlantPathology
🙏 Please share with interested candidates!
🌱 Start: October 2025
📅 Deadline: 12th January 2025
🇬🇧 Open to UK students
💰 Fully funded
ℹ️ More info: tinyurl.com/w6ap9v9f
❗ #PlantImmunity #PlantPathology
🙏 Please share with interested candidates!
Bioengineering of plant NLR (nucleotide-binding leucine-rich repeat) immune receptors to enhance disease resistance at Imperial College London on FindAPhD.com
PhD Project - Bioengineering of plant NLR (nucleotide-binding leucine-rich repeat) immune receptors to enhance disease resistance at Imperial College London, listed on FindAPhD.com
www.findaphd.com
December 4, 2024 at 12:59 PM
If you're from the UK and are looking for a PhD, don't miss out on this fantastic opportunity! Amazing lab and amazing project!
Reposted by Angus Bucknell
Come join us at the Centre Programmable Biological Matter 👇
🚀 We’re hiring! 🚀
We are seeking a passionate PDRA to lead an exciting AMS funded project in designing dynamic protein cage-based vaccines.
Utilise state-of-the-art biochemistry and deep learning tools to create systems with real-world impact.
durham.taleo.net/careersectio...
We are seeking a passionate PDRA to lead an exciting AMS funded project in designing dynamic protein cage-based vaccines.
Utilise state-of-the-art biochemistry and deep learning tools to create systems with real-world impact.
durham.taleo.net/careersectio...
December 3, 2024 at 12:21 PM
Come join us at the Centre Programmable Biological Matter 👇
Reposted by Angus Bucknell
Last few days to apply for a PhD studentship in my group @thesainsburylab.bsky.social
biodtp.norwichresearchpark.ac.uk/projects/ide...
biodtp.norwichresearchpark.ac.uk/projects/ide...
Identification of novel virulence determinants in the rice blast fungus Magnaporthe oryzae | Doctoral Training Partnership
TALBOT_S25DTP
biodtp.norwichresearchpark.ac.uk
November 19, 2024 at 4:36 PM
Last few days to apply for a PhD studentship in my group @thesainsburylab.bsky.social
biodtp.norwichresearchpark.ac.uk/projects/ide...
biodtp.norwichresearchpark.ac.uk/projects/ide...
Reposted by Angus Bucknell
Our work on a Phytophthora WY effector that hijacks a host is now out in MPMI! Check it out here: doi.org/10.1094/MPMI...
The WY domain of an RxLR effector drives interactions with a host target phosphatase to mimic host r...
Plant pathogens manipulate the cellular environment of the host to facilitate infection and colonization, often leading to plant diseases. To accomplish this, many specialized pathogens secrete virule...
doi.org
November 8, 2023 at 10:43 PM
Our work on a Phytophthora WY effector that hijacks a host is now out in MPMI! Check it out here: doi.org/10.1094/MPMI...
Reposted by Angus Bucknell
Another MIBTP PhD opportunity, in collaboration with @djgibbs.bsky.social. It turns out ferns are really hard to drown! How do they sense and survive low oxygen and what can this tell us about the evolution of O2 sensing mechanisms in plants?
warwick.ac.uk/fac/cross_fa...
I'm holding my breath...
warwick.ac.uk/fac/cross_fa...
I'm holding my breath...
November 3, 2023 at 6:08 PM
Another MIBTP PhD opportunity, in collaboration with @djgibbs.bsky.social. It turns out ferns are really hard to drown! How do they sense and survive low oxygen and what can this tell us about the evolution of O2 sensing mechanisms in plants?
warwick.ac.uk/fac/cross_fa...
I'm holding my breath...
warwick.ac.uk/fac/cross_fa...
I'm holding my breath...
Reposted by Angus Bucknell
#Plantscience
We have an exciting new NERC CENTA PhD opportunity at Brum, aiming to understand why oaks take so long to flower, how climate change could affect this and how we might speed oak up!
CENTA.ac.uk/studentship
Project 2024-B38.
Please spread the word to anyone who might be interested. 🙂
We have an exciting new NERC CENTA PhD opportunity at Brum, aiming to understand why oaks take so long to flower, how climate change could affect this and how we might speed oak up!
CENTA.ac.uk/studentship
Project 2024-B38.
Please spread the word to anyone who might be interested. 🙂
October 27, 2023 at 9:16 AM
#Plantscience
We have an exciting new NERC CENTA PhD opportunity at Brum, aiming to understand why oaks take so long to flower, how climate change could affect this and how we might speed oak up!
CENTA.ac.uk/studentship
Project 2024-B38.
Please spread the word to anyone who might be interested. 🙂
We have an exciting new NERC CENTA PhD opportunity at Brum, aiming to understand why oaks take so long to flower, how climate change could affect this and how we might speed oak up!
CENTA.ac.uk/studentship
Project 2024-B38.
Please spread the word to anyone who might be interested. 🙂
Great time at the TSL student/postdoc pumpkin carving social today! 🎃
📸 by Matt Wengler
📸 by Matt Wengler
October 26, 2023 at 6:37 PM
Great time at the TSL student/postdoc pumpkin carving social today! 🎃
📸 by Matt Wengler
📸 by Matt Wengler
Reposted by Angus Bucknell
Come and join us @benitez_lab as a PhD candidate! exciting new research in beta 1,3 glucans, intercellular communication and plant development.
Deadline for Expression of Interest is early January! Detail here www.findaphd.com/phds/project...
Deadline for Expression of Interest is early January! Detail here www.findaphd.com/phds/project...
October 26, 2023 at 5:46 PM
Come and join us @benitez_lab as a PhD candidate! exciting new research in beta 1,3 glucans, intercellular communication and plant development.
Deadline for Expression of Interest is early January! Detail here www.findaphd.com/phds/project...
Deadline for Expression of Interest is early January! Detail here www.findaphd.com/phds/project...
Absolute marathon getting to Bristol yesterday. Went straight from TSL at 4:00 pm and got into Bristol at 00:30 am!
October 21, 2023 at 10:49 AM
Absolute marathon getting to Bristol yesterday. Went straight from TSL at 4:00 pm and got into Bristol at 00:30 am!
For some reason Asda didn’t do a Magnaporthe throw, but tried to match it to the PhD theme as much as possible!
October 1, 2023 at 10:59 AM
For some reason Asda didn’t do a Magnaporthe throw, but tried to match it to the PhD theme as much as possible!
Very excited for day 2 of my PhD at TSL. @talbotlabtsl.bsky.social and the group have been very welcoming, looking forward to some good research over the next few years!
September 27, 2023 at 7:08 AM
Very excited for day 2 of my PhD at TSL. @talbotlabtsl.bsky.social and the group have been very welcoming, looking forward to some good research over the next few years!