Anna Williams
annawilliamslab.bsky.social
Anna Williams
@annawilliamslab.bsky.social
Education 42%
Computer science 18%

Reposted by Anna Williams

Join Calton Consort for “Midwinter” at Canongate Kirk, 5pm on Saturday 6th December — perfectly timed to head straight to that party or head home to cosy up afterwards. ❄️🎶

Tickets are selling fast… don’t miss out!

www.ticketsource.co.uk/whats-on/edi...

The lab went to our institute Halloween party as research models- spot yeast, human, E.coli, naked mole rat, axolotl, fusing organoid, frog, drosophila, excitatory neuron and oligodendrocyte!!!

We have an exciting PhD position available in the Williams lab related to cerebral small vessel disease and funded through our Racing Against Dementia project - if you are interested then do apply here: regenerative-medicine.ed.ac.uk/postgraduate...
www.findaphd.com/phds/project...
PhD opportunities | Centre for Regenerative Medicine | Centre of Regenerative Medicine
Information about available funded PhD Positions
regenerative-medicine.ed.ac.uk

And he won the Ian Wilmut Prize! Hurray!

Reposted by Anna Williams

Amazing talk by Karl from our @annawilliamslab.bsky.social (who was also nominated for the Wilmut Prize) about his PhD work on Oligodenrocyte Progenitors and their differentiation potentials at the CRM away day.

The Edinburgh participants at dinner at VasCog!

Ronja gets the top abstract prize at Vascog!!

Trials are happening in MS right now- to find out if it really works in people with MS. They should report fairly soon....🙂

The lab is having a good few months for publications with this one as well in case you missed it: doi.org/10.1016/j.ym...
www.sciencedirect.com/science/arti...

(Thank you Themis and Francesca, and all!)
The lncRNA MYRACL regulates human oligodendrocyte maturation and myelination
Recent studies have described disease-associated expression patterns of long non-coding RNAs (lncRNAs) associated with neurodevelopment and neurodegen…
www.sciencedirect.com

Our new paper on metformin, myelin, mitochondria and metabolism is now out at rdcu.be/eDbFD
Thanks to Nina and all of the team!
Metformin alters mitochondria-related metabolism and enhances human oligodendrocyte function
Nature Communications - Metformin is under clinical trial for brain neuroprotection but how it may work is poorly understood. Here, the authors show that metformin helps myelin formation by human...
rdcu.be

Reposted by Anna Williams

Now out in Molecular Therapy! With Francesca Vacante, we describe MYRACL, a novel candidate lncRNA driving human oligodendroglia differentiation & myelination. Grateful to our amazing co-authors & mentors @annawilliamslab.bsky.social & Andrew Baker!

Read more👇
www.sciencedirect.com/science/arti...

Reposted by Anna Williams

On National Receptionist's Day we would like to thank our fantastic reception team for all they bring to our Institute. They are the friendly face of IRR and help make our staff, students and visitors feel so welcome. Thank you! #NationalReceptionistsDay

Reposted by Anna Williams

For those who want a distraction and/ or are interested, here's the latest from the group, led by Phil Braaker

www.nature.com/articles/s41...
Activity-driven myelin sheath growth is mediated by mGluR5 - Nature Neuroscience
Employing pharmacology, genetics and all-optical approaches in zebrafish, Braaker et al. find that neuronal activity influences the growth of myelin sheaths along axons by signaling through metabotrop...
www.nature.com

Reposted by Anna Williams

EDINBURGH AXOLOTLS!

Super-excited to hear my wonderful colleague @aidarodrigo.bsky.social on BBC Radio 4 talking about the axototl colony she has established in our institute @edinuni-irr.bsky.social 😃

Available on BBC sounds: Aida's section starts at 23.37

www.bbc.co.uk/sounds/play/...
BBC Inside Science - How vulnerable is our power supply? - BBC Sounds
Massive power cuts brought parts of Spain, Portugal and France to a standstill this week.
www.bbc.co.uk

Reposted by Anna Williams

Genetic subtypes predict multiple sclerosis severity and response to treatment #NeuroDegeneration 🧪🧠
http://medrxiv.org/cgi/content/short/2025.04.15.25325853v1

Reposted by Anna Williams

📣 Open call for early-career composers. 📣

The successful applicant will be invited to collaborate with the choir in a composition, and receive £1000 upon completion of the work.
🔹Deadline: 25th April 2025
🔹Details: caltonconsort.org.uk/compose/

Reposted by Anna Williams

Today I met @rodtmitchell.bsky.social at our Fringe bootcamp. We will be representing the @edinuni-irr.bsky.social at the @edfringe.bsky.social this year! Super excited. Lot's of thought-provoking talks by amazing academics - stay tuned!

Reposted by Anna Williams

"Neurons are like trees with roots and branches that talk!" was my favourite comment from a 4-year old from my last workshop for #BrainAwarenessWeek at the Little Muslims children's group. Thanks @edinuni-irr.bsky.social and @edinunineuro.bsky.social for the support!

Reposted by Anna Williams

The findings from my focus group project on #dementia and #multimorbidity are now available to download as an infographic

Thanks to the Global Brain Health Institute and @nrs-ndn1.bsky.social for supporting this work. It was an enjoyable and illuminating process!

www.gbhi.org/projects/exp...
Exploring the Priorities of People with Dementia and Multiple Conditions | Global Brain Health Institute
Most people with dementia have at least two further health conditions. However, research usually studies dementia on its own. People with several co-existing conditions are often excluded from drug tr
www.gbhi.org

Reposted by Anna Williams

"Your brain is your superpower!" was the takehome message of my second workshop for #BrainAwarenessWeek2025. So glad to represent @edinuni-irr.bsky.social and @edinunineuro.bsky.social again at Danderhall Primary School.

Reposted by Anna Williams

Reposted by Anna Williams

It’s international woman’s day! Well we have a lot of amazing women in our group to celebrate from our fierce leader @annawilliamslab.bsky.social to our PhD students, postdocs, bioinformaticians, and everyone in between💪🏻 Thank you ladies for being amazing scientists, colleagues and friends 💜💙🩵

Reposted by Anna Williams

📢 We are hiring! 📢

We are looking for a postdoc to help us work out why mice cannot regenerate the spinal cord but spiny mice *can*.

More info and how to apply: tinyurl.com/4m6yzbef

Get in touch if interested!
Postdoctoral Research Associate
We are looking for a Postdoctoral Research Associate to join our group at the Centre for Regenerative Medicine (CRM) and the Institute for Regeneration and Repair (IRR), The University of Edinburgh.
tinyurl.com

Reposted by Anna Williams

Book your tickets in advance at www.ticketsource.co.uk/calton-consort
7:30pm Saturday 22nd March
Canongate Kirk

Reposted by Anna Williams

Delighted to announce @rikeshrajani.bsky.social as the first Group Leader to join our flagship vascular dementia research centre with @thebhf.bsky.social 🎉👏

The Rajani Lab will investigate how the protective myelin sheath around brain cells is damaged in small vessel disease👉 buff.ly/4hIGaVM

Reposted by Anna Williams

Reposted by Anna Williams

I was thrilled to receive this news—I’ve been awarded the #MSCAPostdoctoralFellowship for my project, PHOS-SVD! Extremely grateful for the support of @annawilliamslab.bsky.social, @nadlerlab.bsky.social and my colleagues for their feedback. Excited to begin the journey into membrane lipid research!

Reposted by Anna Williams

Reposted by Anna Williams

Reposted by Anna Williams

⚠️Useful!⚠️

Protocol for assessing myelination by human iPSC-derived oligodendrocytes in Shiverer mouse ex vivo brain slice cultures

by Themistoklis Tsarouchas, @erinmgibson.bsky.social @lidazoupi.bsky.social
@annawilliamslab.bsky.social

#neurosky

www.sciencedirect.com/science/arti...
Protocol for assessing myelination by human iPSC-derived oligodendrocytes in Shiverer mouse ex vivo brain slice cultures
Human induced pluripotent stem cell (iPSC)-derived oligodendrocytes are a powerful tool for studying aberrant myelination in neurodegenerative and neu…
www.sciencedirect.com