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Carrie Freed, Pharm.D., BCIDP, AAHIVP @apothecarrie.bsky.social · Apr 13

Ooo SNAP!

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Carrie Freed, Pharm.D., BCIDP, AAHIVP @apothecarrie.bsky.social · Mar 15

Interesting!

Carrie Freed, Pharm.D., BCIDP, AAHIVP @apothecarrie.bsky.social · Feb 18

Acceptable

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Carrie Freed, Pharm.D., BCIDP, AAHIVP @apothecarrie.bsky.social · Feb 18

Have I been working with someone who says CTX this whole time? 😱

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Carrie Freed, Pharm.D., BCIDP, AAHIVP @apothecarrie.bsky.social · Feb 18

You and me both, for the exact reason 😂

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Carrie Freed, Pharm.D., BCIDP, AAHIVP @apothecarrie.bsky.social · Dec 31

Based on the pharmacokinetic studies I’ve read with oritavancin, I doubt it would have an issue staying above that MIC, one 1,200 mg dose seemingly gets to 100 mcg/mL in the serum as a peak. Those who actually use oritavancin (I haven’t) are free to correct me though! doi:10.1007/s40801-020-00188-6

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Carrie Freed, Pharm.D., BCIDP, AAHIVP @apothecarrie.bsky.social · Dec 31

Not necessarily, but compared to other isolates identified by EUCAST, 0.125 mcg/mL is a higher MIC than the majority. It would depend on the site of infection and if > 0.125 mcg/mL concentration of oritavancin can get there adequately.

Carrie Freed, Pharm.D., BCIDP, AAHIVP @apothecarrie.bsky.social · Dec 31

There’s no direct ECOFF on EUCAST for oritavancin for E. faecium, however out of 320 observations, 41 had an MIC of 0.125 and only 8 were above that MIC. I’d say it’s on the higher end of comfort, but no great data for clinical outcomes.

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Carrie Freed, Pharm.D., BCIDP, AAHIVP @apothecarrie.bsky.social · Dec 30

*** Except when clinically indicated 😌 Kidding. I’ll check my fridge when I get home, I’m curious now.

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Carrie Freed, Pharm.D., BCIDP, AAHIVP @apothecarrie.bsky.social · Dec 30

* For legal reasons this is a joke, and antibiotics are great when used appropriately! 😝

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Carrie Freed, Pharm.D., BCIDP, AAHIVP @apothecarrie.bsky.social · Dec 30

Me, an antimicrobial steward:

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Carrie Freed, Pharm.D., BCIDP, AAHIVP @apothecarrie.bsky.social · Dec 21

Thank you 😊

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Carrie Freed, Pharm.D., BCIDP, AAHIVP @apothecarrie.bsky.social · Dec 20

Lol. You know me so well.

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Carrie Freed, Pharm.D., BCIDP, AAHIVP @apothecarrie.bsky.social · Dec 17

Ooo, will have to look

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Carrie Freed, Pharm.D., BCIDP, AAHIVP @apothecarrie.bsky.social · Dec 14

Adding mine in 😄 happy Caturday from Wheatley and Dewey!

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Carrie Freed, Pharm.D., BCIDP, AAHIVP @apothecarrie.bsky.social · Nov 30

Agree! All our med students heavily rely on Sketchy. I haven’t dug into it yet – but I will since all of them do!

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Carrie Freed, Pharm.D., BCIDP, AAHIVP @apothecarrie.bsky.social · Nov 30

For sure, she fit it in perfectly for those in-between moments. Planning to order my set soon!

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Carrie Freed, Pharm.D., BCIDP, AAHIVP @apothecarrie.bsky.social · Nov 30

Honestly, @empiricgame.bsky.social’s card set was great to learn some of the antibiotics. My ID preceptor (back when I was training) @ashpergillus.bsky.social played with me during my rotation and I learned a ton. Planning to implement it for my students 😝

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Carrie Freed, Pharm.D., BCIDP, AAHIVP @apothecarrie.bsky.social · Nov 23

Eep, a bit scary. Not for us since we use carbapenems as our B-lactams anyway, but I’ve been OK with TZP in uncomplicated urinary ESBL infections in the past.

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Reposted by Carrie Freed, Pharm.D., BCIDP, AAHIVP

Antibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · Nov 20

🔥Everyone's favorite #shorterisbetter table is updated🔥
"BALANCE is now published,
so the table is now updated!
GNB bacteremia is now listed as Bacteremia(non S.aureus)
Neary 5,000 patients have now been randomized to 1 vs. 2 Constantine Units for non S. aureus bacteremia " Dr.Spellberg #idsky

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Carrie Freed, Pharm.D., BCIDP, AAHIVP @apothecarrie.bsky.social · Nov 20

#InBALANCEWeTrust

paul evan bunce, md @paulbuncemd.bsky.social · Nov 20

BALANCE is out! 7 days of antibiotics non-inferior to 14 days for bacteremia (excluding S. aureus).

this is a practice-changing study that should have huge impacts on antibiotic prescribing.

i also can't say enough about the study team (esp. nick daneman). inspiring.

www.nejm.org/doi/full/10....

Antibiotic Treatment for 7 versus 14 Days in Patients with Bloodstream Infections | NEJM

Bloodstream infections are associated with substantial morbidity and mortality. Early, appropriate antibiotic therapy is important, but the duration of treatment is uncertain. In a multicenter, non...

www.nejm.org

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Carrie Freed, Pharm.D., BCIDP, AAHIVP @apothecarrie.bsky.social · Nov 19

As long as it isn’t cefdinir I’m happy.

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Reposted by Carrie Freed, Pharm.D., BCIDP, AAHIVP

Stanford Antimicrobial Safety & Sustainability Program @stanfordasp.bsky.social · Nov 18

Happy 🟪 Antibiotic Awareness Week 🟪

Along with presentations, we will be raffling off microbe pins, keychains, and gift cards!

What are you doing for #USAAW24?

#IDSky #MedSky

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Carrie Freed, Pharm.D., BCIDP, AAHIVP @apothecarrie.bsky.social · Nov 18

I feel like this has to be how ibrexafungerp was named

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Carrie Freed, Pharm.D., BCIDP, AAHIVP @apothecarrie.bsky.social · Nov 18

Happy World Antimicrobial Awareness Week #WAAW! In honor of WAAW, I wanted to do a quick word unscramble of some of our common antibiotics 💊 Can you guess them?

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