Alessandro Romanel
@aromanel.bsky.social
Head of the Bioinformatics and Computational Genomics Lab, CIBIO, University of Trento.
🚨 Out in NAR @narjournal.bsky.social!
Introducing HapScoreDB: a database of protein language model functional scores for haplotype-resolved protein sequences.
📄 Paper: doi.org/10.1093/nar/...
💻 DB: bcglab.cibio.unitn.it/hapscoredb
#Bioinformatics #Genomics #ProteinLanguageModels #CompBio
Introducing HapScoreDB: a database of protein language model functional scores for haplotype-resolved protein sequences.
📄 Paper: doi.org/10.1093/nar/...
💻 DB: bcglab.cibio.unitn.it/hapscoredb
#Bioinformatics #Genomics #ProteinLanguageModels #CompBio
HapScoreDB: a database of protein language model functional scores for haplotype-resolved protein sequences
Abstract. Deciphering the functional effects of genetic variants, especially those inherited together on the same haplotype, remains a major challenge in h
doi.org
November 25, 2025 at 9:25 AM
🚨 Out in NAR @narjournal.bsky.social!
Introducing HapScoreDB: a database of protein language model functional scores for haplotype-resolved protein sequences.
📄 Paper: doi.org/10.1093/nar/...
💻 DB: bcglab.cibio.unitn.it/hapscoredb
#Bioinformatics #Genomics #ProteinLanguageModels #CompBio
Introducing HapScoreDB: a database of protein language model functional scores for haplotype-resolved protein sequences.
📄 Paper: doi.org/10.1093/nar/...
💻 DB: bcglab.cibio.unitn.it/hapscoredb
#Bioinformatics #Genomics #ProteinLanguageModels #CompBio
Reposted by Alessandro Romanel
Our latest collaborative project co-led by Dario De Felice, Alessandro Alaimo, @bresdavide.bsky.social, and Andrea Lunardi at CIBIO UniTrento 🔬 🧫 🧬
We generated pro-luminal prostate organoid models and found that common FOXA1 cancer indels are loss-of-function
www.embopress.org/doi/full/10....
We generated pro-luminal prostate organoid models and found that common FOXA1 cancer indels are loss-of-function
www.embopress.org/doi/full/10....
Rarγ-Foxa1 signaling promotes luminal identity in prostate progenitors and is disrupted in prostate cancer | EMBO reports
imageimageLeveraging mouse adult prostate organoids reveals regulators of prostatic luminal
lineage commitment. The androgen pathway together with retinoic acid/Rarγ/Foxa1 signaling
programs luminal p...
www.embopress.org
December 4, 2024 at 4:57 PM
Our latest collaborative project co-led by Dario De Felice, Alessandro Alaimo, @bresdavide.bsky.social, and Andrea Lunardi at CIBIO UniTrento 🔬 🧫 🧬
We generated pro-luminal prostate organoid models and found that common FOXA1 cancer indels are loss-of-function
www.embopress.org/doi/full/10....
We generated pro-luminal prostate organoid models and found that common FOXA1 cancer indels are loss-of-function
www.embopress.org/doi/full/10....
Reposted by Alessandro Romanel
Are you looking for a tool to analyze ChIP-seq data with spike-in control?
Check out SpikeFlow 👇
academic.oup.com/nargab/artic...
Check out SpikeFlow 👇
academic.oup.com/nargab/artic...
SpikeFlow: automated and flexible analysis of ChIP-Seq data with spike-in control
Abstract. ChIP with reference exogenous genome (ChIP-Rx) is widely used to study histone modification changes across different biological conditions. A key
academic.oup.com
January 24, 2025 at 2:53 PM
Are you looking for a tool to analyze ChIP-seq data with spike-in control?
Check out SpikeFlow 👇
academic.oup.com/nargab/artic...
Check out SpikeFlow 👇
academic.oup.com/nargab/artic...