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Reposted by A.S.Brumm

Niakan Lab @niakanlab.bsky.social · 10d

One of our favourite tabs is Resources: we're listing all of our datasets, codes, beginning to upload and make accessible raw imaging data and lab protocols. Please check it out, we hope this is useful!

niakanlab.com/resources/

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Reposted by A.S.Brumm

Teresa Rayon @trayon.bsky.social · Jul 24

Found this unbelievably accurate “integrated stem
cell model” by JA Thomson in 1996 of marmoset ESCs 🐒

pubmed.ncbi.nlm.nih.gov/8828827/

The simplest protocol one can think of built quite remarkable structures !?!?

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Reposted by A.S.Brumm

PLOS Biology @plosbiology.org · Jul 16

Measuring properties of individual cells in relation to their neighbors in 3D tissues is challenging. @cellysally.bsky.social &co develop a computational toolkit to facilitate this, analyzing developmental patterning in mouse, chick & #Drosophila #embryo @plosbiology.org 🧪 plos.io/4lQMeNu

Patterning of cell identities in the posterior E8.5 mouse embryo. Co-expression of mesoderm marker TBXT (blue) and neural marker SOX2 (green) identifies cells in the neuromesodermal (NMP) progenitor region at the intersection of their respective gene expression gradients. TBX6 (red) marks paraxial mesoderm and also marks sporadic mesoderm-committed cells emerging within the NMP region. LAMINB1 (white) marks the nuclear envelope of all cells. Credit: Matthew French.

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Biology Open @biologyopen.bsky.social · Jul 1

Can peer review be done faster, without compromising on quality? Biology Open has embarked on an exciting experiment to find out - Editor-in-Chief Dan Gorelick @danielgorelick.bsky.social explains.

www.youtube.com/watch?v=Tt5h...

Why is Biology Open's Fast & Fair peer review initiative exciting?

YouTube video by The Company of Biologists

www.youtube.com

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Reposted by A.S.Brumm

Sally Lowell @cellysally.bsky.social · Jun 24

Join us! This will be a great meeting.

Royal Society Publishing @royalsocietypublishing.org · Jun 24

Are you a biologist with a research interest in #embryogenesis or synthetic biology? Join our upcoming residential scientific meeting in Brighton on the topic of generative biology: royalsociety.org/science-even... ‪@jcornwallscoones.bsky.social ‪@dbenzinger.bsky.social @cellysally.bsky.social

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A.S.Brumm @asbrumm.bsky.social · May 28

Our protocol with all the details you'll need to detect and quantify phospo-SMAD proteins in your (human) embryo, is finally out today @cp-starprotocols.bsky.social.
Thanks again to my wonderful co-author @toddfallesen.bsky.social and the @niakanlab.bsky.social.
www.sciencedirect.com/science/arti...

Protocol for immunofluorescence detection and quantification of phosphorylated SMAD proteins in human blastocysts

The transforming growth factor β (TGF-β) signaling superfamily includes NODAL and bone morphogenetic protein (BMP) signaling, which lead to the phosph…

www.sciencedirect.com

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Reposted by A.S.Brumm

Katherine Brown @katherine-brown.bsky.social · Mar 25

If you’re a PhD or postdoc developmental biologist in the UK who cares about the field and the community, please nominate yourself to join the BSDB committee. Great opportunity to get involved, have real input and give back to the community @bsdb.bsky.social #biologists100

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A.S.Brumm @asbrumm.bsky.social · Mar 24

Excited to share how we use neighbour labelling to investigate cell fate decisions in neuromesodermal progenitors. Find me at Poster 165 @biologists.bsky.social #biologists100.

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Jen Annoh @jens-cells.bsky.social · Mar 17

🧪Attending your first scientific #conference? Thinking about what to pack, or just looking to make sure you prepared all the essentials? Have a look at The Beginner’s Guide to Scientific Conferences I got to publish for @the-node.bsky.social, out now! ☺️☺️ thenode.biologists.com/the-beginner...

the-beginners-guide-to-scientific-conferences

The Beginners Guide to Scientific Conferences

thenode.biologists.com

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Reposted by A.S.Brumm

Babraham Institute @babrahaminst.bsky.social · Feb 26

Have you been following the work of the HDBI - the Human Developmental Biology Initiative? A lay summary of a recent paper from researchers involved in the HDBI is now available, written by the paper's first author @asbrumm.bsky.social
hdbi.org/human-epibla...
#Embryos #HumanDevelopment

Text reads: The ability of cells in early human embryos to become more specialised does not depend on a process previously thought necessary from work in stem cell models.

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A.S.Brumm @asbrumm.bsky.social · Feb 25

A lay summary of this work is now available: hdbi.org/human-epibla...

Special thanks once again to Kathy @niakanlab.bsky.social and Richard Acton at @babrahaminst.bsky.social

Human epiblast pluripotency is Nodal independent — HDBI - Human Development Biology Initiative

The ability of cells in early human embryos to become more specialised does not depend on a process previously thought necessary from work in stem cell models

hdbi.org

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Reposted by A.S.Brumm

André Dias @dias-andre.bsky.social · Jan 13

www.biorxiv.org/content/10.1...

Here we explore the role of #Wnt and #Nodal signalling during mammalian gastrulation using #gastruloids. Building on the work of many labs, we propose that antagonistic signalling-dependent #modularity in the PS establishes the early mammalian body plan.

A temporal coordination between Nodal and Wnt signalling governs the emergence of the mammalian body plan

Nodal and Wnt signalling play an important role in the emergence of the mammalian body plan, primarily by orchestrating gastrulation and primitive streak formation. While the literature suggests that ...

www.biorxiv.org

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