Benjamin Tseng
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benjamintseng.com
Benjamin Tseng
@benjamintseng.com
Builder passionate for deeptech; 8+ yrs x-border deeptech VC; All opinions mine alone
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My 30s were a wild decade of learning things about being a parent & about how the world works. As I head into the next decade, I've been reflecting on the lessons that have reshaped how I see the world.

Here are 7 of them. 🧵
Shocking but not at the same time

Chinese DeepSeek model (the 670B reasoning one) produces 50% more security vulnerabilities when a politically sensitive "trigger word" (eg Taiwan, Tibet, Uyghur) is present in the request

www.crowdstrike.com/en-us/blog/c...
CrowdStrike Researchers Identify Hidden Vulnerabilities in AI-Coded Software
CrowdStrike researchers reveal how trigger words cause DeepSeek-R1 to generate vulnerable code—exposing new AI-driven risks in software development.
www.crowdstrike.com
November 29, 2025 at 4:55 PM
The final Buffett letter includes this charming anecdote & suggestion to us all on how to live a good life

Text of the full letter: www.berkshirehathaway.com/news/nov1025...
November 11, 2025 at 12:25 AM
I'm generally optimistic about AI technology (yes, even for our careers) ... with one exception, and the data is starting to prove my fears right

benjamintseng.com/2025/11/whos...
Who’s Jobs are AI Taking Right Now?
Despite all the speculation over why Amazon is laying off 14,000 workers, as of this writing, and with a few exceptions I’ll note below, I don’t personally worry a great deal about AI t…
benjamintseng.com
November 4, 2025 at 7:22 AM
Reposted by Benjamin Tseng
November 3, 2025 at 11:58 PM
My 30s were a wild decade of learning things about being a parent & about how the world works. As I head into the next decade, I've been reflecting on the lessons that have reshaped how I see the world.

Here are 7 of them. 🧵
October 19, 2025 at 9:08 PM
How you know it's time to start thinking about selling...
September 28, 2025 at 8:45 PM
Gene therapy for Huntington's Disease shows 75% slowdown in progression over 36 month clinical trial!

Amazing feat — working gene therapy + targeted surgery + synthetic control arm — and for company uniQure (who's seeing a 3x stock price bump on the news)

benjamintseng.com/2025/09/gene...
Gene therapy for Huntington’s shows promising clinical trial data
Huntington’s Disease is one of the classic “uncurable” neurodegenerative diseases. A genetic mutation produces a mutant form of a protein (called Huntingtin) which leads to sudden…
benjamintseng.com
September 24, 2025 at 11:46 PM
Reposted by Benjamin Tseng
Death from sub-acute sclerosing panencephalitis (SSPE) in a child in Los Angeles
SSPE is a rare sequel of #measles infection that appears years after the initial infection, and is uniformly fatal. So sorry for this family. As things are going on the US, we'll be seeing more of these cases.
Child dies from rare measles-related complication, LA County health officials say
Health officials reported the death of a Los Angeles County child from a complication of measles infection acquired during infancy.
abc7.com
September 11, 2025 at 8:54 PM
The Surrealism of Authoritarianism -- a look at life under Xi Jinping outlines some of the hallmarks of authoritarian rule benjamintseng.com/2025/09/the-...
The Surrealism of Authoritarianism
Among the obvious hallmarks of authoritarianism are: Arbitrary paranoia from on high — where students singing patriotic songs on bike rides are suddenly viewed to be a threat Contradiction be…
benjamintseng.com
September 7, 2025 at 9:11 PM
You are buying this shirt because you're a Swiftie

I'm buying this shirt to protest the Chinese Communist party

We are not the same 🤣
August 27, 2025 at 8:10 PM
Listening to a medical informatics professor talk to a Med Student who thought he could vibe code through a data analysis & fail because he doesnt understand how the code or the data works 🤦🏻‍♂️

Vibe coding can be great: but don't use it where it matters if you can't check it
August 15, 2025 at 4:51 PM
Amazing technical feat but does this not defeat the purpose of block chain as distributed ledger if you need to rely on a database hosted at a cloud provider?

How blockchain network Keeta processes 11 million transactions per second with Spanner | Google Cloud Blog share.google/dvfJQGpayOBh...
How blockchain network Keeta processes 11 million transactions per second with Spanner | Google Cloud Blog
A recent public stress test verified that Keeta Network’s transaction volume significantly outperformed traditional layer-1 blockchains.
share.google
August 15, 2025 at 2:44 PM
Are we at the start of a new golden age of antimicrobial discovery?

The lower cost of metagenomics + our better understanding of biosynthetic gene clusters + new computational methods = we may outrun the awful "end of antibiotics" that's fast approaching

benjamintseng.com/2025/08/new-...
New Age Bioprospecting for Antimicrobials
One of the major contributors to improved healthcare outcomes and reduced mortality in the post-World War II era was the widespread use of antibiotics. Able to treat infection, these miracle drugs …
benjamintseng.com
August 12, 2025 at 2:11 AM
This is a good thing in the neverending war on weaponized misinformation

If only we could get X to do the same... www.cnbc.com/2025/07/21/y...
YouTube wipes out thousands of propaganda channels linked to China, Russia, others
Google removed YouTube channels and other accounts linked to RT, the Russian state-controlled media outlet accused of paying prominent conservative influencers.
www.cnbc.com
July 22, 2025 at 2:59 AM
Nice look by the team @notion.com on how they approached making their centrally hosted MCP server (and why their first attempt to just map tools to API calls wasn't ideal)

www.notion.com/blog/notions...
Notion’s hosted MCP server: an inside look
Earlier this year, we got requests for a Notion MCP server that would let AI agents work directly with Notion workspaces. Here’s how we built it, from our initial open-source experiment to today’s hos...
www.notion.com
July 21, 2025 at 9:10 PM
Oldie but goodie in these times
June 23, 2025 at 4:01 PM
Apparently this is the stage of Big tech capitalism we're in now...
June 22, 2025 at 4:27 PM
Reposted by Benjamin Tseng
This is incredibly tragic. His light was bright.
I heard this morning that my informatics colleague Dr. Atul Butte passed after a battle with cancer. He was a giant in the field & inspired many of us over his distinguished career. He was a passionate champion of the power of big data & his impact on our field is immeasurable. RIP Atul & thanks.
June 14, 2025 at 5:53 PM
Reposted by Benjamin Tseng
I heard this morning that my informatics colleague Dr. Atul Butte passed after a battle with cancer. He was a giant in the field & inspired many of us over his distinguished career. He was a passionate champion of the power of big data & his impact on our field is immeasurable. RIP Atul & thanks.
June 14, 2025 at 1:20 PM
Reposted by Benjamin Tseng
DAVE: Open the podbay doors, ChatGPT.
CHATGPT: Certainly, Dave, the podbay doors are now open.
DAVE: The podbay doors didn't open.
CHATGPT: My apologies, Dave, you're right. I thought the podbay doors were open, but they weren't. Now they are.
DAVE: I'm still looking at a set of closed podbay doors.
June 9, 2025 at 6:04 PM
Meanwhile, on the other app...
June 5, 2025 at 9:15 PM
Now when they say "can you hear the world's smallest violin playing just for you?", you have a reference point...

Physicists create 'the world's smallest violin' using nanotechnology phys.org/news/2025-06...
Physicists create 'the world's smallest violin' using nanotechnology
Physicists at Loughborough University have used cutting-edge nanotechnology to create what they believe may be "the world's smallest violin," which is small enough to fit within the width of a human h...
phys.org
June 4, 2025 at 6:17 PM
June 3, 2025 at 9:20 PM
Incredible -- first ever successful RCT for CAR-T therapy in solid tumors

www.nature.com/articles/d41...
Cancer-fighting CAR T cells show promising results for hard-to-treat tumours
Trial in China is one of the first times the immune therapy has worked against solid tumours.
www.nature.com
June 3, 2025 at 3:09 PM