BF Francis Ouellette
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bffo.bsky.social
BF Francis Ouellette
@bffo.bsky.social
3.1K followers 4.8K following 420 posts
Bioinformatics 🧬🖥️🧪
#PLOS Comp Biol Education Sect. Editor;
#DATABASE OUP Associate Editor;
#OpenScience #OpenAccess #OpenData;
friend of @jxtxfoundation.bsky.social,
@abinstitute.bsky.social
- I am 🇨🇦
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bffo.bsky.social
BF Francis Ouellette @bffo.bsky.social · Nov 29
Be Open so the world can see how great you are!

#OpenScience
#OpenAccess
#OpenData
#OpenSource
#OpenEducationalResources
bffo.bsky.social
From @stephenturner.us | Rubrics, Not Vibes: Consistency as a Feature in Peer Review with AI | 🧪 #AI #OpenScience #PeerReview #Grants #Publications #PairedEnds
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blog.stephenturner.us/p/rubrics-no...
Rubrics, Not Vibes: Consistency as a Feature in Peer Review with AI
Responsibly using AI for a structured first pass manuscript / grant proposal review can reduce reviewer variance while keeping human judgment central. Bonus: a prompt I use for my own draft proposals.
blog.stephenturner.us
February 18, 2026 at 5:24 PM
Reposted by BF Francis Ouellette
stephenturner.us
Staying Current in Data Science and Computational Biology: 2026 Edition. Part 3 in a series of posts going back 14 years. doi.org/10.59350/2na...
Staying Current in Data Science and Computational Biology: 2026 Edition
Part 3 in a series of posts going back 14 years
doi.org
January 1, 2026 at 10:15 AM
bffo.bsky.social
From @jeanetteeb.bsky.social & colleagues in @plos.org #Computational #Biology | Tutorial for variant interrogation in tumor samples | #Bioinformatics #Education #NGS #Cancer #Genomics #OpenEducationalResources #OpenScience 🧬 🖥️ 🧪 🔓 CC/ @ppalagi.bsky.social
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journals.plos.org/ploscompbiol...
Tutorial for variant interrogation in tumor samples
The increasing accessibility of next-generation sequencing has empowered researchers to investigate somatic mutations in cancer. The complexity of variant analysis pipelines, terminology, and tool sel...
journals.plos.org
February 18, 2026 at 5:07 PM
bffo.bsky.social
From @bebatut.bsky.social @abretaud.bsky.social @hrhotz.bsky.social et al. in @plos.org #Computational #Biology | Ten common misconceptions about Galaxy (and why they are wrong!) | #Bioinformatics #Education #UseGalaxy 🧬 🖥️ 🧪 🔓 CC/ @galaxyproject.bsky.social
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journals.plos.org/ploscompbiol...
Ten common misconceptions about Galaxy (and why they are wrong!)
Author summary Galaxy is a free, community-built web interface that helps scientists analyse data in a way that’s easy to use, transparent and reproducible. While it is widely used in biology and othe...
journals.plos.org
February 18, 2026 at 4:58 PM
bffo.bsky.social
From @stephenturner.us | Staying Current in Data Science and Computational Biology: 2026 Edition | #DataScience #ComputationalBiology #Bioinformatics |
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open.substack.com/pub/stephent...
Staying Current in Data Science and Computational Biology: 2026 Edition
Part 3 in a series of posts going back 14 years
open.substack.com
February 17, 2026 at 1:35 PM
bffo.bsky.social
Very interesting post from @stephenturner.us | #Bioinformatics #AI #Education
February 17, 2026 at 1:11 PM
Reposted by BF Francis Ouellette
criskotsu.bsky.social
Keep science accessible 🧪
The misuse of colour in science communication - Nature Communications
The accurate representation of data is essential in science communication, however, colour maps that visually distort data through uneven colour gradients or are unreadable to those with colour vision...
www.nature.com
February 15, 2026 at 11:51 PM
Reposted by BF Francis Ouellette
socdevbio.bsky.social
Before there’s a heartbeat, there’s this little glowing heart in the neural tube 💕 Chicken neural crest cells in magenta. 📸Image by Rocío Márquez, Strobl-Mazzulla Lab @pstrobl.bsky.social #FluorescentFriday #SciValentine
February 14, 2026 at 3:23 AM
bffo.bsky.social
From @plos.org #Computational #Biology | Towards #FAIR and #federated #data ecosystems for interdisciplinary #research | #Bioinformatics #OpenScience 🧬 🖥️ 🧪 🔓 🇩🇪
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journals.plos.org/ploscompbiol...
Towards FAIR and federated data ecosystems for interdisciplinary research
Scientific data management is at a critical juncture, driven by exponential data growth, increasing cross-domain dependencies, and a severe reproducibility crisis in modern research. Traditional centr...
journals.plos.org
February 14, 2026 at 4:41 PM
Reposted by BF Francis Ouellette
jaggakatja.bsky.social
The legacy of Amos Bairoch, the resources he and others created (Swiss-Prot, UniProt, PROSITE, ENZYME, ExPASy, neXtProt, Cellosaurus), his commitment to open access and high-quality curation, is immense and have guided bioinformatics to this day.
February 13, 2026 at 5:26 PM
bffo.bsky.social
From #OUP 's @bioinfoadv.bsky.social journal | Amos Bairoch (1957-2025): pioneer of bioinformatics and founder of Swiss-Prot | #Bioinformatics #Proteomics #OpenScience CC/ @sib.swiss 🧬 🖥️ 🧪 🔓🇨🇭
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academic.oup.com/bioinformati...
Amos Bairoch (1957–2025): pioneer of bioinformatics and founder of Swiss-Prot
Amos Bairoch, one of the founding figures of bioinformatics, passed away on 1 December 2025 at the age of 68 (SIB Swiss Institute of Bioinformatics 2025a).
academic.oup.com
February 13, 2026 at 5:14 PM
bffo.bsky.social
From #OUP 's #Briefings in Bioinformatics journal | Pathways, outputs and impact of #NIH -supported #bioinformatics & #genomics graduate trainees in #Africa | #Education #OpenScience #H3ABionet #H3Africa 🧬 🖥️ 🧪 🔓
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academic.oup.com/bib/article/...
Pathways, outputs and impact of NIH-supported bioinformatics and genomics graduate trainees in Africa
Abstract. Global biomedical and health research is increasingly relying on genomic and computational approaches, largely driven by the increasing volumes o
academic.oup.com
February 13, 2026 at 5:02 PM
Reposted by BF Francis Ouellette
kristiholmes.bsky.social
Learn more about #CGR at www.ncbi.nlm.nih.gov/comparative-...

CGR is a terrific project and huge contribution to our research data and tooling ecosystem!
About CGR
About the NIH Comparative Genomics Resource (CGR)
www.ncbi.nlm.nih.gov
February 12, 2026 at 5:01 PM
Reposted by BF Francis Ouellette
kristiholmes.bsky.social
Excited to share this new #CGR paper 🤩 It has been a real joy to work with the awesome NIH/NLM/NCBI team. HUGE kudos to paper lead E Tvedte & thanks also to coauthors! Thank you CGR working group, NIH exec steering committee, T Murphy, & V Schneider for championing the #CGR vision forward!
February 12, 2026 at 5:00 PM
bffo.bsky.social
From @lrasmus.bsky.social, @kristiholmes.bsky.social et al. in @plos.org #Computational #Biology | Ten quick tips for using the NIH Comparative Genomics Resource | #Bioinformatics #Education #Genomics #PLOSCBQT #NCBI 🧬 🖥️ 🧪 🔓 CC/ @ppalagi.bsky.social
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journals.plos.org/ploscompbiol...
Ten quick tips for using the NIH Comparative Genomics Resource
journals.plos.org
February 12, 2026 at 2:02 PM
bffo.bsky.social
Glad to discover the latest #Bioinformatics User
Group from Edmonton (YEG). Adding to the
family (in historical order).
vanbug.org
monbug.ca
torbug.org
yegbug.ca
Good that the older BUGs aren't using airport codes. It would get awkward!
YVRbug
YULbug
YYZbug
🧬 🖥️ 🧪 #OpenEducationalResources
VanBUG
vanbug.org
February 10, 2026 at 7:46 PM
bffo.bsky.social
From #NCBI Insight | NCBI Celebrates International Love Data Week! | #Bioinformatics #Genomics #Proteomics #OpenData #OpenScience 🧬 🖥️ 🧪
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ncbiinsights.ncbi.nlm.nih.gov/2026/02/10/n...
NCBI Celebrates International Love Data Week! - NCBI Insights
Providing free and open access to scientific literature and data   Do you love biomolecular data as much as we do? Join NCBI in celebrating International Love Data Week, February 9-13, 2026! Love Data...
ncbiinsights.ncbi.nlm.nih.gov
February 10, 2026 at 6:43 PM
Reposted by BF Francis Ouellette
rmwaterhouse.bsky.social
And here is the course announcement: www.sib.swiss/training/cou...
February 6, 2026 at 3:49 PM
Reposted by BF Francis Ouellette
matttg.bsky.social
Just down the road… Dino’s have to be in those rocks also! ⚒️🧪
susieoftraken.bsky.social Dr Susannah Lydon @susieoftraken.bsky.social · 12d
A 95 million year old angiosperm leaf preserved as an impression in an iron-cemented sandstone. The original leaf may have gone, but you can still see where invertebrates nibbled it.

From Dakota Formation, Kansas. Cenomanian, probably.

#FossilFriday ⚒🌏🔬🌱🍃🌳
Fossil angiosperm leaf from Dakota Fm, Kansas. Leaf is about 8cm long.
February 7, 2026 at 3:45 PM
bffo.bsky.social
From @dessimoz.bsky.social and colleagues in @nature.com 's #Scientific #Data | The missing link in FAIR data policy: biodata resources in life sciences | #FAIR #Genomics #OpenScience #OpenSource #Proteomics 🧬 🖥️ 🧪 🔓
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www.nature.com/articles/s41...
The missing link in FAIR data policy: biodata resources in life sciences - Scientific Data
In the life sciences, FAIR principles have reshaped research policy, but their implementation still relies largely on individual researchers – many of whom lack the expertise or support needed to make...
www.nature.com
February 7, 2026 at 3:53 PM
Reposted by BF Francis Ouellette
bjesseshapiro.bsky.social
Montreal in February: we eat so much poutine that our dumpsters are overflowing with 180L vats of poutine sauce.

This message brought to you by Tourisme Montréal
A photo of a dumpster in a snowy alleyway with several large white buckets labelled “poutine Québecoise traditional sauce” strewn over the ground
February 5, 2026 at 2:32 PM
bffo.bsky.social
This is the final week to submit your abstract to the Canadian Bioinformatics Hub Conference 2026 | #ActNow #Bioinformatics #OpenScience #Toronto #Canada #GreatScience 🧬 🖥️ 🧪 🔓
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www.iscb.org/cbhc2026/
February 5, 2026 at 11:49 PM
Reposted by BF Francis Ouellette
ehekkala.bsky.social
🦠🧪🧬👇
standupforscience.bsky.social Stand Up for Science! @standupforscience.bsky.social · 12d
BREAKING: Over 680 members of the National Academy of Sciences, Medicine, and Engineering have endorsed articles of impeachment against RFK Jr.
(1/2 🧵)
Top of the photo in white text reads: "BREAKING OVER 680 NATIONAL ACADEMY OF SCIENCES MEMBERS, INCLUDING 10 NOBEL PRIZE LAUREATES, ENDORSE IMPEACHING RFK JR." Below that in black text is a statement reading: "We, the undersigned Members of the National Academy of Medicine, the National Academy of Sciences, and the National Academy of Engineering, writing in our private capacities, endorse the Articles of Impeachment introduced in the House of Representatives on Dec 10, 2025 by Representative Haley Stevens." Below that is the red "STAND UP FOR SCIENCE " logo. Below that is a link in white text reading: "standupforscience.net/impeach-rfkjr".
February 5, 2026 at 11:38 PM
Reposted by BF Francis Ouellette
winnipegfreepress.com
OTTAWA – The launch of a new Canadian diplomatic mission in Greenland is sparking hopes for more collaboration on climate change, Inuit rights and defence in the face of U.S. President Donald Trump’s annexation threats.
New Greenland consulate sparks hopes for joint action on climate change, defence
OTTAWA – The launch of a new Canadian diplomatic mission in Greenland is sparking hopes for more collaboration on climate change, Inuit rights and defence in the face of U.S. President Donald Trump’s annexation threats.
www.winnipegfreepress.com
February 5, 2026 at 12:25 PM
Reposted by BF Francis Ouellette
ronbeavis.bsky.social
While I admire their optimism, is there really enough reliable information to provide a corpus on the topic? I have tried to use variant effect predictions multiple times for about a decade & it hasn't really provided any coherent results.
February 3, 2026 at 2:24 PM