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Breast International Group @bigxresearch.bsky.social · 8d

👋 Last week we welcomed Dr. Roberto Salgado to the BIG office to talk about his upcoming #SABCS25 presentation on BIG’s exploratory #APHINITY #TILs research. Stay tuned! Insights coming soon!

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Breast International Group @bigxresearch.bsky.social · 14d

Yesterday at #BePrecise2025, @aftimosp highlighted #AURORA, an academic study led by @BIGxResearch & mainly supported by @BCRFCure. It identifies genetic changes in mBC—showcasing how molecular profiling drives #precisiononcology to guide treatment & improve outcomes
@be__precise

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Breast International Group @bigxresearch.bsky.social · 14d

Today, BIG’s team, Virginie Adam & Thayane Crestani, are at #BePrecise2025, where collaboration between clinicians & researchers highlights how #precisiononcology can enhance patient care: Cancer profiling, Targeted therapies, Multi-omics, AI & molecular imaging. @be__precise

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Breast International Group @bigxresearch.bsky.social · Aug 28

🎉 The EXPERT trial has reached its recruitment target! Thanks to all the participants. This trial will be able to confirm if the Prosigna (PAM50) assay can identify women who may safely omit radiation therapy after breast cancer surgery. @BCTrialsANZ

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Breast International Group @bigxresearch.bsky.social · Aug 19

New pub 📢 The #POSITIVEtrial manuscript led by @IDemeestere has been published in The Breast! It explores hormonal factors predictive of fertility in young women with #breastcancer interrupting #endocrinetherapy to try for pregnancy. @etop_ibcsg

🔗 www.thebreastonline.com/article/S096...

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Reposted by Breast International Group

Séamus O’Reilly MDPhD @seamusoreilly.bsky.social · Jul 14

🙋‍♂️ How can we 📈 access to innovation for ALL patients with breast caner ❓
@bigxresearch.bsky.social commentary 📝👇

www.nature.com/articles/s41...

🙏 to co-authors✍️

Successes of the past ✅
Pitfalls of the present ✅
Solutions for the future eg OptimaYoung 👇

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Breast International Group @bigxresearch.bsky.social · Jul 15

📢 New open-access article in npj Breast Cancer, co-authored by BIG’s leadership, explores the challenges of academic clinical trials and how to ensure their future impact.

📄 Read more: www.nature.com/articles/s41... #BIGAgainstBreastCancer #breastcancer #research

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Reposted by Breast International Group

Julia Maués @itsnotpink.bsky.social · Jun 30

What an honor to join the Executive Board of @bigxresearch.bsky.social! As someone living w metastatic breast cancer & connected to many other patients, I’m excited to support research that reflects what truly matters to people dealing with this disease.
🔗 bigagainstbreastcancer.org/about-big/go...

Governance

BIG is dedicated to supporting all research stakeholders and facilitating ethically sound human research for breast cancer.

bigagainstbreastcancer.org

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Breast International Group @bigxresearch.bsky.social · Jun 20

Earlier this week, our team attended the first AI in Oncology conference in Paris, led by Prof. Fabrice André. A brilliant exchange on how AI is shaping cancer research and care. Thank you IHU PRISM for an inspiring first edition! #AIinOncology @PrismCenter

Breast International Group @bigxresearch.bsky.social · Jun 12

Our Scientific Advisor, Thayane Crestani, is attending the @EORTC Course on Clinical Trial Statistics for Non-Statisticians in Brussels, strengthening our team’s expertise to support better clinical research in breast cancer, from study design to data interpretation. 💡📊 📈

Breast International Group @bigxresearch.bsky.social · Jun 10

We are thrilled to announce a new collaboration with @paige_ai , leaders in AI-driven cancer digital pathology. Our partnership aims to combine BIG’s clinical trial expertise & data w Paige's AI capabilities to revolutionize #breastcancer research & care 🔗 bit.ly/4kzSsBd

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Breast International Group @bigxresearch.bsky.social · Jun 4

🧬 BIG’s Scientific Director, Virginie Adam, spoke to RTBF about the results from #SERENA-6 presented at #ASCO25. A blood test to detect molecular recurrence + new treatment cut the risk of progression by 56%!

📖 Read more (in FR): www.rtbf.be/article/canc...

Breast International Group @bigxresearch.bsky.social · Jun 4

#SOFT&TEXT trials are the result of over 20 years of collaboration. Thank you to patients and their families, HC providers, study chairs and committees, collaborators, the cross-Atlantic groups & the funders. @etop_ibcsg @theNCI @BCRFcure #ASCO25

Breast International Group @bigxresearch.bsky.social · Jun 2

Happening NOW at #ASCO25 !! Poster presented by @GuiNaderMarta on long-term outcomes of patients with HER2-positive invasive lobular carcinoma in the #ALTTOtrial ! Go check poster 135! @JulesBordet @DanaFarber @Harvard

Breast International Group @bigxresearch.bsky.social · Jun 2

Happening NOW at #ASCO25 !! Poster 119 presented by @KristinaFanucci on evaluation of treatment-related neutropenia as a predictor of response to adjuvant #palbociclib in the #PALLASTrial @ABCSGVienna @alliance_trials

Breast International Group @bigxresearch.bsky.social · Jun 2

TREAT ctDNA trial

A BIG supporter study led by @EORTC compares #elacestrant vs. standard ET in ER+/HER2- BC pts with #ctDNA relapse. Enrollment is open in 12 countries and will involve 120 sites. Go check 210b TiP poster presented by @MIgnatiadis at #ASCO25. #bcsm

Breast International Group @bigxresearch.bsky.social · Jun 2

The voice of Early Career Investigators is heard at the #BIG-NCTN Annual Meetings, Drs @darioT_ and @io_zerdes are speaking on the need for #younginvestigators ' involvement and support in patient-centered #clinicalresearch. @theNCI @bcrfcure.bsky.social

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Breast International Group @bigxresearch.bsky.social · Jun 2

#ASCO25: Assessment of #breastcancer Index benefit in #premenopausal pts receiving OFS-containing adjuvant #endocrinetherapy was compared btw #SOFT&TEXT cohorts and validation of the prognostic performance of BCI was conducted, go check Poster #150
@etop_ibcsg
@oreganruth

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Breast International Group @bigxresearch.bsky.social · May 30

Thank you to Dr. @BraunMDPhD for his great talk at the 2025 #BIG-NCTN Annual Meeting. Here, he explains how cancer vaccines work to treat cancer. @theNCI @BCRFcure @YaleCancer #ASCO25 #vaccines #breastcancer

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Breast International Group @bigxresearch.bsky.social · May 29

Day 2 of the 2025 BIG-NCTN Annual Meeting in Chicago is ongoing to continue discussions on #breastcancer research and how joint efforts can be accomplished. @BCRFcure @theNCI

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Breast International Group @bigxresearch.bsky.social · May 29

Day 1 of the BIG-NCTN Annual Meeting finishes with a dinner gathering all participants from both BIG and @theNCI networks and @BCRFcure leaders to celebrate the 20th Anniversary of the BIG_NCTN collaboration. @OncoAlert

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Breast International Group @bigxresearch.bsky.social · May 26

New publication in the European Journal of Cancer: Prognostic relation of body mass index on extended aromatase inhibition treatment in postmenopausal pts with ER+ #breastcancer: A retrospective analysis of the #SOLE trial 🔗www.ejcancer.com/article/S0959-8049(25)00219-9/fulltext @OncologyAdvance

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Breast International Group @bigxresearch.bsky.social · May 23

An abstract (e23009) has now been published at #ASCO25 on the BIG - Patient Partnership model for facilitating meaningful patient involvement in the design and conduct of cancer research, click here to read: meetings.asco.org/abstracts-pr...

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Breast International Group @bigxresearch.bsky.social · May 22

#ESMObreast25 has come to a close with major insights from BIG studies. From long-term survival data to fertility and patient-reported outcomes, here are key takeaways from the event. #Aphinitytrial #Optimatrial #Positivetrial #ALTTOtrial #Pallastrial #ALPHABETtrial #BCSM

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Breast International Group @bigxresearch.bsky.social · May 19

@TanjaSpanic at #ESMOBreast25 speaks about the importance of patients' involvement in #clinicalresearch
@EORTC_QLG @EuropaDonnaEUR

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