Biohub
@biohub.org
Combining frontier AI & frontier biology to help scientists cure or prevent disease
Pinned
Biohub
@biohub.org
· Nov 6
Joining Bluesky to share breakthroughs, tools and ideas from Biohub — and to learn from the science and tech folks already building here. 👋
We’re partnering with @tahoetherapeutics.bsky.social and @archive.org to generate the largest perturbation dataset for virtual cell models.
Announced today at #JPM2026, the 120M+ cell dataset will be open source to accelerate development of biological foundation models. https://bit.ly/4pBkZbd
Announced today at #JPM2026, the 120M+ cell dataset will be open source to accelerate development of biological foundation models. https://bit.ly/4pBkZbd
Biohub, Arc Institute, Tahoe partner on largest perturbation dataset
Generation of 120M+ cells and 225,000 perturbation interactions will accelerate virtual cell model development.
bit.ly
January 12, 2026 at 6:45 PM
We’re partnering with @tahoetherapeutics.bsky.social and @archive.org to generate the largest perturbation dataset for virtual cell models.
Announced today at #JPM2026, the 120M+ cell dataset will be open source to accelerate development of biological foundation models. https://bit.ly/4pBkZbd
Announced today at #JPM2026, the 120M+ cell dataset will be open source to accelerate development of biological foundation models. https://bit.ly/4pBkZbd
Alex Walsh is recognized for her development of label-free optical imaging technologies that enable the non-invasive metabolic monitoring of single cells.
spie.org/news/alex-wa...
spie.org/news/alex-wa...
Alex Walsh: The 2026 SPIE Early Career Achievement Award – Academic Focus
For innovations in label-free optical microscopy through integration of fluorescence lifetime imaging and machine learning, and for outstanding mentorship and service contributions within the communit
spie.org
January 9, 2026 at 7:37 PM
Alex Walsh is recognized for her development of label-free optical imaging technologies that enable the non-invasive metabolic monitoring of single cells.
spie.org/news/alex-wa...
spie.org/news/alex-wa...
Hui Cao’s work in mesoscopic physics and complex media has advanced our understanding of light-matter interactions, specifically through her development of unconventional lasers and multimodal fibers.
spie.org/news/hui-cao...
spie.org/news/hui-cao...
Hui Cao: The 2026 SPIE Mozi Award
For pioneering work in novel light sources, and demonstrating a wide range of applications in imaging, sensing, and random number generation
spie.org
January 9, 2026 at 7:37 PM
Hui Cao’s work in mesoscopic physics and complex media has advanced our understanding of light-matter interactions, specifically through her development of unconventional lasers and multimodal fibers.
spie.org/news/hui-cao...
spie.org/news/hui-cao...
Kimani Toussaint is recognized for his commitment to diversifying STEM and his leadership in creating research opportunities for underrepresented students in optics and photonics.
spie.org/news/kimani-...
spie.org/news/kimani-...
spie.org
January 9, 2026 at 7:37 PM
Kimani Toussaint is recognized for his commitment to diversifying STEM and his leadership in creating research opportunities for underrepresented students in optics and photonics.
spie.org/news/kimani-...
spie.org/news/kimani-...
Maryellen Giger's work in AI-driven image analysis has advanced computer-aided diagnosis and its clinical translation. This honor also recognizes her mentorship of the next generation of medical-imaging scientists.
spie.org/news/maryell...
spie.org/news/maryell...
spie.org
January 9, 2026 at 7:34 PM
Maryellen Giger's work in AI-driven image analysis has advanced computer-aided diagnosis and its clinical translation. This honor also recognizes her mentorship of the next generation of medical-imaging scientists.
spie.org/news/maryell...
spie.org/news/maryell...
We're honored to see familiar faces among the winners of the 2026 #SPIE Society Awards 🧵
Congratulations to all of the recipients for your achievements across light-based sciences and technologies.
Congratulations to all of the recipients for your achievements across light-based sciences and technologies.
We are excited to announce the recipients of the 2026 #SPIE Society Awards! ✨🎉
Honoring transformative advancements across a variety of professional areas, these awards recognize technical accomplishments & committed service to SPIE.
Let's congratulate the 21 recipients.
spie.org/news/spie-an...
Honoring transformative advancements across a variety of professional areas, these awards recognize technical accomplishments & committed service to SPIE.
Let's congratulate the 21 recipients.
spie.org/news/spie-an...
January 9, 2026 at 7:28 PM
We're honored to see familiar faces among the winners of the 2026 #SPIE Society Awards 🧵
Congratulations to all of the recipients for your achievements across light-based sciences and technologies.
Congratulations to all of the recipients for your achievements across light-based sciences and technologies.
How close are we to programmable human cells?
A new @cellpress.bsky.social perspective from Martha Gillette and Yogesh Goyal explores how synthetic biology & AI are enabling precise control over cell behavior, opening new paths for drug development and personalized therapies. https://bit.ly/48Mx1JO
A new @cellpress.bsky.social perspective from Martha Gillette and Yogesh Goyal explores how synthetic biology & AI are enabling precise control over cell behavior, opening new paths for drug development and personalized therapies. https://bit.ly/48Mx1JO
January 8, 2026 at 6:50 PM
How close are we to programmable human cells?
A new @cellpress.bsky.social perspective from Martha Gillette and Yogesh Goyal explores how synthetic biology & AI are enabling precise control over cell behavior, opening new paths for drug development and personalized therapies. https://bit.ly/48Mx1JO
A new @cellpress.bsky.social perspective from Martha Gillette and Yogesh Goyal explores how synthetic biology & AI are enabling precise control over cell behavior, opening new paths for drug development and personalized therapies. https://bit.ly/48Mx1JO
Reposted by Biohub
Together with @ronghuizhu.bsky.social, we are thrilled to present our new perturb-seq study of 22M primary CD4+ T cells, across donors and timepoints – the result of a decade-long collaboration between the Marson @marsonlab.bsky.social and Pritchard @jkpritch.bsky.social labs 🧵 tinyurl.com/gwt2025
Genome-scale perturb-seq in primary human CD4+ T cells maps context-specific regulators of T cell programs and human immune traits
Gene regulatory networks encode the fundamental logic of cellular functions, but systematic network mapping remains challenging, especially in cell states relevant to human biology and disease. Here, ...
tinyurl.com
January 5, 2026 at 6:42 PM
Together with @ronghuizhu.bsky.social, we are thrilled to present our new perturb-seq study of 22M primary CD4+ T cells, across donors and timepoints – the result of a decade-long collaboration between the Marson @marsonlab.bsky.social and Pritchard @jkpritch.bsky.social labs 🧵 tinyurl.com/gwt2025
WaveOrder is a powerful new #microscopy tool from Biohub that helps researchers reconstruct messy microscope data into clean, quantitative maps. It’s grounded in physics & it’s already changing how we see biology.
📚 Preprint https://bit.ly/4jgDJLB
🔬WaveOrder: https://czi.co/4pMwGgb
📚 Preprint https://bit.ly/4jgDJLB
🔬WaveOrder: https://czi.co/4pMwGgb
January 5, 2026 at 3:06 PM
WaveOrder is a powerful new #microscopy tool from Biohub that helps researchers reconstruct messy microscope data into clean, quantitative maps. It’s grounded in physics & it’s already changing how we see biology.
📚 Preprint https://bit.ly/4jgDJLB
🔬WaveOrder: https://czi.co/4pMwGgb
📚 Preprint https://bit.ly/4jgDJLB
🔬WaveOrder: https://czi.co/4pMwGgb
🧪 That's a wrap on #CellBio2025! We had a blast in Philly connecting with the cell biology and imaging communities, and sharing our open-access tools!
December 12, 2025 at 4:47 PM
🧪 That's a wrap on #CellBio2025! We had a blast in Philly connecting with the cell biology and imaging communities, and sharing our open-access tools!
Reposted by Biohub
Join us for the AI Applications in Biology Symposium at @biohub.org! A full day of talks on ML for structural biology, imaging, single-molecule & multimodal/omics data
🗓️ Feb. 20, 2026 (1 day before BPS)
📍San Francisco
🔗 shorturl.at/uQerL
Attend in-person or virtual. Submit abstracts by Jan. 20!
🗓️ Feb. 20, 2026 (1 day before BPS)
📍San Francisco
🔗 shorturl.at/uQerL
Attend in-person or virtual. Submit abstracts by Jan. 20!
December 9, 2025 at 5:09 PM
Join us for the AI Applications in Biology Symposium at @biohub.org! A full day of talks on ML for structural biology, imaging, single-molecule & multimodal/omics data
🗓️ Feb. 20, 2026 (1 day before BPS)
📍San Francisco
🔗 shorturl.at/uQerL
Attend in-person or virtual. Submit abstracts by Jan. 20!
🗓️ Feb. 20, 2026 (1 day before BPS)
📍San Francisco
🔗 shorturl.at/uQerL
Attend in-person or virtual. Submit abstracts by Jan. 20!
Reposted by Biohub
I'll be at the AI Virtual Cells and Instruments: A New Era in Drug Discovery and Development.
Stop by to chat about generative models and virtual cells! I'll be presenting our work @biohub.org on a scalable latent diffusion model for single-cell gene expression data.
Stop by to chat about generative models and virtual cells! I'll be presenting our work @biohub.org on a scalable latent diffusion model for single-cell gene expression data.
December 6, 2025 at 5:17 PM
I'll be at the AI Virtual Cells and Instruments: A New Era in Drug Discovery and Development.
Stop by to chat about generative models and virtual cells! I'll be presenting our work @biohub.org on a scalable latent diffusion model for single-cell gene expression data.
Stop by to chat about generative models and virtual cells! I'll be presenting our work @biohub.org on a scalable latent diffusion model for single-cell gene expression data.
It’s our favorite time of year - hot cocoa & #CellBio2025! Come find us at booth 301 and see some of our latest tools for capturing novel biological insights across scales.
December 4, 2025 at 6:51 PM
It’s our favorite time of year - hot cocoa & #CellBio2025! Come find us at booth 301 and see some of our latest tools for capturing novel biological insights across scales.
📍#NeurIPS2025! Stop by booth #833 to explore AI-powered tools pushing biology forward:
🧬VariantFormer—predicts how genetic variants affect gene expression
💡scLDM—simulates single-cell data on demand for virtual experiments
🔬ESMC + ESM3—foundational models for protein structure, function & evolution
🧬VariantFormer—predicts how genetic variants affect gene expression
💡scLDM—simulates single-cell data on demand for virtual experiments
🔬ESMC + ESM3—foundational models for protein structure, function & evolution
December 3, 2025 at 4:55 PM
📍#NeurIPS2025! Stop by booth #833 to explore AI-powered tools pushing biology forward:
🧬VariantFormer—predicts how genetic variants affect gene expression
💡scLDM—simulates single-cell data on demand for virtual experiments
🔬ESMC + ESM3—foundational models for protein structure, function & evolution
🧬VariantFormer—predicts how genetic variants affect gene expression
💡scLDM—simulates single-cell data on demand for virtual experiments
🔬ESMC + ESM3—foundational models for protein structure, function & evolution
📣 #NeurIPS2025 Expo Talk: “Building an AI Ecosystem for Multiscale Biological Discovery” w/ Dari Kimanius + Jonathan Schwartz. Today 4–5pmPT.
Learn how open cryoET pipelines, multimodal datasets & the virtual cell are helping bridge imaging + AI across biological scales. bit.ly/4py5Wj4
Learn how open cryoET pipelines, multimodal datasets & the virtual cell are helping bridge imaging + AI across biological scales. bit.ly/4py5Wj4
NeurIPS Expo Talk Panel Building an AI Ecosystem for Multiscale Biological DiscoveryNeurIPS 2025
bit.ly
December 2, 2025 at 11:19 PM
📣 #NeurIPS2025 Expo Talk: “Building an AI Ecosystem for Multiscale Biological Discovery” w/ Dari Kimanius + Jonathan Schwartz. Today 4–5pmPT.
Learn how open cryoET pipelines, multimodal datasets & the virtual cell are helping bridge imaging + AI across biological scales. bit.ly/4py5Wj4
Learn how open cryoET pipelines, multimodal datasets & the virtual cell are helping bridge imaging + AI across biological scales. bit.ly/4py5Wj4
Stunning cover to celebrate the incredible work from @loicaroyer.bsky.social's team.
Learn more about Ultrack, a powerful tool for fast, accurate and scalable cell tracking: biohub.org/life-science... 🧪
Learn more about Ultrack, a powerful tool for fast, accurate and scalable cell tracking: biohub.org/life-science... 🧪
Our November issue is now live! 🎉
www.nature.com/nmeth/volume...
On the cover, cell tracking in a developing zebrafish embryo visualized using Ultrack. Cover by Alexandre Dizieux, Jordão Bragantini, Loic Royer, Merlin Lange, CZ Biohub. Paper here: www.nature.com/articles/s41...
www.nature.com/nmeth/volume...
On the cover, cell tracking in a developing zebrafish embryo visualized using Ultrack. Cover by Alexandre Dizieux, Jordão Bragantini, Loic Royer, Merlin Lange, CZ Biohub. Paper here: www.nature.com/articles/s41...
November 14, 2025 at 7:23 PM
Stunning cover to celebrate the incredible work from @loicaroyer.bsky.social's team.
Learn more about Ultrack, a powerful tool for fast, accurate and scalable cell tracking: biohub.org/life-science... 🧪
Learn more about Ultrack, a powerful tool for fast, accurate and scalable cell tracking: biohub.org/life-science... 🧪
We’re thrilled to see this work on the cover! Congrats again, @loicaroyer.bsky.social + team!
November 14, 2025 at 7:22 PM
We’re thrilled to see this work on the cover! Congrats again, @loicaroyer.bsky.social + team!
💡What if you could simulate cells before lab experiments? Meet scLDM: an AI model that generates realistic single-cell data on demand. Specify conditions like tissue type and perturbations—scLDM predicts what happens. Virtual experiments to accelerate discovery. bit.ly/scldm
Modeling cellular diversity with scLDM
scLDM is a deep generative AI model that creates realistic single-cell data to advance virtual cell research.
bit.ly
November 6, 2025 at 4:32 PM
💡What if you could simulate cells before lab experiments? Meet scLDM: an AI model that generates realistic single-cell data on demand. Specify conditions like tissue type and perturbations—scLDM predicts what happens. Virtual experiments to accelerate discovery. bit.ly/scldm
🧬Introducing VariantFormer: the first AI model that predicts how your genetic variants affect gene expression across different tissues. It helps researchers understand disease mechanisms and accelerate personalized medicine. bit.ly/variantformer
Genomics research for all
VariantFormer is an AI Model that predicts how personal genetic variations affect gene expression across tissues
bit.ly
November 6, 2025 at 4:32 PM
🧬Introducing VariantFormer: the first AI model that predicts how your genetic variants affect gene expression across different tissues. It helps researchers understand disease mechanisms and accelerate personalized medicine. bit.ly/variantformer
🔬We’re launching the Virtual Immune System project—a flagship effort to model the immense complexity of the human immune system, opening the door to engineering health, simulating immune therapies, reprogramming cells & preventing disease before it arises. bit.ly/virtualimmune
The Virtual Immune System: A roadmap for predictive human immunology
Biohub’s Aly Khan on how AI and causal data could make immunology a predictive science.
bit.ly
November 6, 2025 at 4:32 PM
🔬We’re launching the Virtual Immune System project—a flagship effort to model the immense complexity of the human immune system, opening the door to engineering health, simulating immune therapies, reprogramming cells & preventing disease before it arises. bit.ly/virtualimmune
At Biohub, our scientists + technologists are building AI-powered tools to understand biology and advance cures. From translating DNA into cellular behavior with VariantFormer to visualizing molecular structures with our Virtual Immune System—we're pushing the boundaries of science. 👇
November 6, 2025 at 4:32 PM
At Biohub, our scientists + technologists are building AI-powered tools to understand biology and advance cures. From translating DNA into cellular behavior with VariantFormer to visualizing molecular structures with our Virtual Immune System—we're pushing the boundaries of science. 👇
Joining Bluesky to share breakthroughs, tools and ideas from Biohub — and to learn from the science and tech folks already building here. 👋
November 6, 2025 at 4:10 PM
Joining Bluesky to share breakthroughs, tools and ideas from Biohub — and to learn from the science and tech folks already building here. 👋