Brain Evolution News
@brainevolutionnews.bsky.social
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Brain Evolution in the News posted here for you! For events & opportunities in brain evolution research follow @EurNetBrainEvoR.bsky.social http://brainevolutionnews.blogspot.com
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13. Gabi et al. 2010, Brain Behav Evol, doi:10.1159/000319872
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9. Cunha et al. 2022, Front Neuroanat, doi:10.3389/fnana.2022.1048261
10. Teles et al. 2012, J Comp Physiol A, doi:10.1007/s00359-012-0721-6
11. Zupanc 1999, J Exp Biol, doi:10.1242/jeb.202.10.1435
12. Zupanc 2021, J Exp Biol, doi:10.1242/jeb.226357
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brainbyana.bsky.social
5. Olkowicz et al. 2016, PNAS, doi:10.1073/pnas.1517131113
6. Kverková et al. 2022, PNAS, doi:10.1073/pnas.2121624119
7. Herculano-Houzel et al. 2011, Brain Behav Evol, doi:10.1159/000330825
8. Herculano-Houzel et al. 2015, Front Neuroanat, doi:10.3389/fnana.2015.00064
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brainbyana.bsky.social
Bibliography:

1. Jerison 1973, Evolution of the Brain and Intelligence, Academic Press
2. Marhounová et al. 2019, Evolution, doi:10.1111/evo.13805
3. Herculano-Houzel et al. 2007, PNAS, doi:10.1073/pnas.0611396104
4. Herculano-Houzel et al. 2014, Front Neuroanat, doi:10.3389/fnana.2014.00077
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brainbyana.bsky.social
Over generations, step changes → cohorts diverge in brain, body & neuron number.
Some clades (primates, parrots, songbirds) evolve bigger brains with more neurons; others (rodents, sauropsids, mammals) grow brains faster than neurons → lower density 3-6,13.
👉 Plasticity drives brain diversity.
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brainbyana.bsky.social
Across cohorts (different densities):
🐟 Larger fish → larger brains with up to 20× more neurons.
Neuron density = constant or decreasing.
📐 This mirrors well-known interspecies scaling patterns, even though all fish came from the same stock.
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brainbyana.bsky.social
Reaction norm model:
🌍 Environmental step changes (like density) shift whole cohorts into new scaling regimes.
🧬 Within a cohort, individual-level factors (genetics, epigenetics, microenvironment) decouple body, brain, and neuron numbers.
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brainbyana.bsky.social
This pattern contradicts the “numerical matching” hypothesis, which predicts body, brain, and neuron number should always scale together 11, 12.
Instead, brain size and neuron number may be regulated by different mechanisms.
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brainbyana.bsky.social
Within a cohort (same density):
🐟 Larger fish → larger brains, but not more neurons.
Animals with more neurons had higher neuron density instead.
⚡ This extends to fish the brain-scaling pattern seen within individuals of the same species in rodents and birds.
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brainbyana.bsky.social
Across vertebrates, bigger species → bigger brains with more neurons 1-6.
But within a species, this often breaks down 3,7-9.
Tilapia are ideal to test: they keep growing + have adult neurogenesis 10.
Researchers raised them at low vs. high density → up to 30× body size variation in same-age fish.
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brainbyana.bsky.social
Here’s the first paper I contributed to: “Expression of SATB1 and SATB2 in the brain of bony fishes: what fish reveal about evolution”
DOI: doi.org/10.1007/s004...
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avsp.bsky.social
Stabilizing selection in an identified multisensory neuron in blind cavefish www.pnas.org/doi/10.1073/... "The most striking aspect, and potentially warning for the study of the evolution of neuronal cell types, is how clearly all predictions failed"
Picture of A. mexicanus and Astyanax aeneus
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us.theconversation.com
𝘏𝘰𝘮𝘰 𝘧𝘭𝘰𝘳𝘦𝘴𝘪𝘦𝘯𝘴𝘪𝘴, nicknamed "Hobbits," challenges theories about human brain evolution. These 3-foot-tall ancient relatives had small brains but were likely highly capable, crafting tools and hunting pygmy elephants.
Hobbits of Flores evolved to be small by slowing down growth during childhood, new research on teeth and brain size suggests
New research on the size relationship between brains and wisdom teeth suggests that bigger brains aren’t necessarily the driving force in human evolution.
buff.ly
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suelkeekim.bsky.social
Excited to share our recent study on human-specific features of the cerebellum and the unexpected, novel role of zona pellucida protein 2 (ZP2) in synapse development. Grateful to the Sestan lab and all our collaborators for their outstanding contributions. www.biorxiv.org/content/10.1...
Human-specific features of the cerebellum and ZP2-regulated synapse development
Understanding the unique features of the human brain compared to non-human primates has long intrigued humankind. The cerebellum refines motor coordination and cognitive functions, contributing to the...
www.biorxiv.org
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paleotesla.bsky.social
New pop sci article on the hobbits of Flores! Their wisdom teeth provide evidence that they got small by slowing growth after birth.

https://theconversation.com/hobbits-of-flores-evolved-to-be-small-by-slowing-down-growth-during-childhood-new-research-on-teeth-and-brain-size-suggests-261257
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mu-peter.bsky.social
As the saying goes
The bigger the thumb, the bigger the...um... brain

Human dexterity and brains evolved hand in hand 🏺🧪
www.nature.com/articles/s42...

Emphasizes role of manipulative abilities in brain evolution and reveals how neural and bodily adaptations are interconnected in primate evolution
Data and potential scenarios for the coevolutionary relationship between thumb length and brain size across primates.
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bendeskylab.com
New review on how changes in cell type composition in and outside the brain contribute to the evolution of behavior. 🧪

authors.elsevier.com/a/1lihM,LqAZ...
Changes in cell type composition, including cell expansions, cell losses, and novel cell gains, are associated with the evolution of specific behaviors.
Figure credit: Matteo Farinella.
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tibbe-evolneuro.bsky.social
Paul Katz on recognizing neuronal homologues across species in the Evolution of Brain Cell Types seminar.
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pawelburkhardt.bsky.social
Our lab is 2.5 years into #ERC funding✨

Grateful for the support that enabled us to uncover the syncytial nerve net in a ctenophore - a discovery reshaping our understanding of nervous system evolution. Stay tuned for more exciting discoveries to come @erc.europa.eu

www.youtube.com/watch?v=1DAE...
Flying into sensory and mesogleal neurons from a ctenophore (comb jelly).
YouTube video by Pawel Burkhardt
www.youtube.com
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alealisousa.bsky.social
Let's start a conversation about brain evolution!
tibbe-evolneuro.bsky.social
We invite you to connect with the TIBBE community on Mattermost, an open-source platform for real-time discussion and collaboration. This is a great space to share ideas, ask questions, and engage in conversations around the Integrative Biology of Brain Evolution.

tibbe-network.github.io
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tibbe-evolneuro.bsky.social
Maria Antonietta Tosches on Cajal-Retzius cells and the evolution of homologous cell types in the Evolution of Brain Cell Types seminar.