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Dr Fabrício Campos

@camposvet.bsky.social

150 followers 190 following 690 posts

With a degree in Veterinary Medicine from UFPel, a Master's in Microbiology at PPGMAA/UFRGS, and a Ph.D. in Veterinary Science at UFRGS, I am a professor at PPGBIOTEC/UFT and serve as Coordinator at PPGMAA/UFRGS. For more information: www.labinftec.com.br

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Dr Fabrício Campos @camposvet.bsky.social · 1d

#H5N1 #Influenza #OneHealth #Pandemic #Zoonoses
- Bhadelia et al., 2025. doi.org/10.17226/29273
- Li et al., 2025. doi.org/10.1016/j.ji...
- Nooruzzaman et al., 2025. doi.org/10.1038/s415...
10/10

Diagnostic Tools, Gaps, and Collaborative Pathways in Human H5N1 Detection: Rapid Expert Consultation

Read online, download a free PDF.

doi.org

Dr Fabrício Campos @camposvet.bsky.social · 1d

Strengthening diagnostic capacity and integrating animal, human, and environmental health data is not just preventive — it’s the only way to act before the next mutation enables sustained human transmission. 9/10

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Dr Fabrício Campos @camposvet.bsky.social · 1d

These findings stress the need to mitigate zoonotic risks across the food chain, especially after H5N1’s expansion into dairy cattle. The picture is clear: this virus is adapting to new hosts, crossing ecosystems, and testing global surveillance limits. 8/10

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Dr Fabrício Campos @camposvet.bsky.social · 1d

Another study showed H5N1 can remain infectious for up to 120 days in raw-milk cheese under certain pH conditions (6.6–5.8). Though ferrets fed contaminated cheese didn’t get infected, the virus stayed stable — a clear risk in unpasteurized dairy products. 7/10

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Dr Fabrício Campos @camposvet.bsky.social · 1d

The same mutation, now seen in H5N1 from cattle and humans in the U.S., enhances viral replication and transmissibility in mammals. Qinghai acts as a viral convergence node where strains meet and mix, fueling the rise of variants with pandemic potential. 6/10

Dr Fabrício Campos @camposvet.bsky.social · 1d

Meanwhile, evidence of H5N1 adaptation and persistence grows. In China, researchers detected the PB2-E627K mutation — a marker of mammalian adaptation — in brown-hooded gulls at Qinghai Lake, a key migratory hub. It’s the first such finding in wild birds since 2020. 5/10

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Dr Fabrício Campos @camposvet.bsky.social · 1d

These tools must link to real-time genomic databases that track viral evolution and trigger automatic alerts. Preparedness demands not only innovation, but also funding incentives and regulatory flexibility to validate new diagnostic tools during emergencies. 4/10

Dr Fabrício Campos @camposvet.bsky.social · 1d

Most clinical tests only identify influenza A, without distinguishing the subtype — a bottleneck that hinders outbreak control and medical response. Experts call for rapid, scalable, and accessible diagnostics, including point-of-care and home testing platforms. 3/10

Dr Fabrício Campos @camposvet.bsky.social · 1d

A new report warns that, even after 70+ human cases in the U.S., testing remains limited to few labs. 2/10

Dr Fabrício Campos @camposvet.bsky.social · 1d

Post 44 — H5N1: diagnostics, adaptation, and global surveillance

As the H5N1 virus expands its reach among birds and mammals, the gap between viral spread and global detection capacity continues to grow. 1/10

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Dr Fabrício Campos @camposvet.bsky.social · 4d

Brandt et al., 2025. doi.org/10.1093/clin...
Hernando-Asensio et al., 2025. www.sanidad.gob.es/areas/alerta...
Peyre and Hautefeuille, 2025. doi.org/10.35690/978...
Plaza et al., 2025. Dryad. doi.org/10.5061/drya...
Wang et al., 2025. doi.org/10.1038/s442...
15/15

B-216 Development and Performance Evaluation of a Molecular Reference Material for Influenza H5N1 Strain Screening

AbstractBackground. Influenza A H5N1 is a highly pathogenic avian influenza virus strain that poses a significant threat to global public health due to its

doi.org

Dr Fabrício Campos @camposvet.bsky.social · 4d

H5N1 follows the same path: a global, adaptive virus that depends on these joint measures.

#H5N1 #AvianInfluenza #OneHealth #GlobalHealth #Surveillance #Zoonoses #GlobalChange
14/15

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Dr Fabrício Campos @camposvet.bsky.social · 4d

The control of H7N9 in Asia — through the closure of live animal markets and poultry vaccination — showed that coordinated actions reduce human infections. 13/15

Dr Fabrício Campos @camposvet.bsky.social · 4d

These findings reinforce the One Health principle: viruses that cross species boundaries can only be contained through integrated surveillance involving humans, animals, and the environment. 12/15

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Dr Fabrício Campos @camposvet.bsky.social · 4d

This advancement helps standardize assays globally and allows early detection of the virus — an essential step to contain future epidemic waves. 11/15

Dr Fabrício Campos @camposvet.bsky.social · 4d

In addition to field surveillance and vaccines, diagnostics are also advancing. A new study developed a recombinant RNA from the isolate A/cattle/Texas/56283/2024 to be compatible with different diagnostic methods. 10/15

Dr Fabrício Campos @camposvet.bsky.social · 4d

The good news is that a candidate vaccine, named IDCDC-RG80A, showed protection against variants with and without these mutations. 9/15

Dr Fabrício Campos @camposvet.bsky.social · 4d

The A156T substitution creates a new glycosylation site that alters antibody recognition, although it reduces viral replication capacity in human and ferret cells. 8/15

Dr Fabrício Campos @camposvet.bsky.social · 4d

Meanwhile, in the United States, the CDC reported a human case without known exposure, in which the H5N1 virus presented two unprecedented mutations in hemagglutinin (P136S and A156T). 7/15

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Dr Fabrício Campos @camposvet.bsky.social · 4d

This sociability favors contagion: the more individuals gathered, the greater the sharing of water, food, and secretions. 6/15

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Dr Fabrício Campos @camposvet.bsky.social · 4d

Another study revealed that the risk areas for H5N1 now cover almost the entire planet, after an explosive expansion between 2020 and 2025. The most affected birds are gregarious species — those that live in groups — tolerant of urban environments, such as gulls and crows. 5/15

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Dr Fabrício Campos @camposvet.bsky.social · 4d

Although the risk of direct transmission to humans is still considered very low, the Spanish Ministry of Health recommends not feeding birds, avoiding contact with carcasses, and keeping pets on a leash. 4/15

Dr Fabrício Campos @camposvet.bsky.social · 4d

The H5N1 virus, once restricted to wild environments, now circulates from the Arctic to urban parks. In Spain, new outbreaks were detected in public parks in Seville and Guadalajara, raising concern over the proximity between birds and people. 3/15

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Dr Fabrício Campos @camposvet.bsky.social · 4d

In today’s post, I gathered five recent articles that integrate surveillance in humans, animals, and the environment. 2/15

Dr Fabrício Campos @camposvet.bsky.social · 4d

Post 43 — H5N1: the virus that adapted to the world (and to cities)

Even publishing twice a week, it’s hard to keep up with all the new studies on H5N1 — a clear sign of the severity and speed with which this panzootic is evolving. 1/15

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