Carlotta Ronda
@carlottaronda.bsky.social
Principal Investigator @innovativegenomics.bsky.social| @ucberkeleyofficial.bsky.social |🧬 CRISPR’ing connections between microbes & humans | 🌱 Systems & SynBio innovator | 🌎 Microbiomes Designer |👩🏼🔬STEM advocate| @simonsfoundation.org FellowAlumna
🚨 A probiotic that secretes a GLP-1–triggering peptide.
By engineering E. coli Nissle to secrete a microbial peptide that stimulates host GLP-1 release, we uncovered a new connection between the microbiome, metabolism, and gut inflammation.
👉 science.org/doi/10.1126/...
By engineering E. coli Nissle to secrete a microbial peptide that stimulates host GLP-1 release, we uncovered a new connection between the microbiome, metabolism, and gut inflammation.
👉 science.org/doi/10.1126/...
Engineered probiotic restores GLP-1 signaling to ameliorate fiber-deficiency exacerbated colitis
Engineered probiotic delivers bacterial peptide that enhances GLP-1 and restores barrier integrity in diet-modulated colitis.
science.org
November 18, 2025 at 1:44 AM
🚨 A probiotic that secretes a GLP-1–triggering peptide.
By engineering E. coli Nissle to secrete a microbial peptide that stimulates host GLP-1 release, we uncovered a new connection between the microbiome, metabolism, and gut inflammation.
👉 science.org/doi/10.1126/...
By engineering E. coli Nissle to secrete a microbial peptide that stimulates host GLP-1 release, we uncovered a new connection between the microbiome, metabolism, and gut inflammation.
👉 science.org/doi/10.1126/...
Thrilled to finally share the latest chapter of our in situ microbiome editing work: “Metagenomic editing of commensal bacteria in vivo using CRISPR-associated transposases”, now out in @science.org 👉 www.science.org/doi/10.1126/...
Metagenomic editing of commensal bacteria in vivo using CRISPR-associated transposases
Although metagenomic sequencing has revealed a rich microbial biodiversity in the mammalian gut, methods to genetically alter specific species in the microbiome are highly limited. Here, we introduce ...
www.science.org
November 18, 2025 at 1:37 AM
Thrilled to finally share the latest chapter of our in situ microbiome editing work: “Metagenomic editing of commensal bacteria in vivo using CRISPR-associated transposases”, now out in @science.org 👉 www.science.org/doi/10.1126/...
Reposted by Carlotta Ronda
I am so honored to receive this award, it was truly a team effort!
🥂 Congratulations to IGI's HS Chau WIES Fellow Carlotta Ronda @rondalab.bsky.social! She is receiving $1 million in non-dilutive seed funding from the HS Chau Foundation to support her new startup. Read more her work in creating cutting-edge microbial medicines: ow.ly/nq8t50WZI8X
#entrepreneurship
#entrepreneurship
September 22, 2025 at 5:37 PM
I am so honored to receive this award, it was truly a team effort!
Reposted by Carlotta Ronda
ICYMI: IGI's Carlotta Ronda @rondalab.bsky.social is part of a team that developed a novel way to precisely edit the genomes of microbes in the #microbiome to defeat harmful infections. Learn more: ow.ly/taTJ50WTA7b
September 10, 2025 at 5:20 PM
ICYMI: IGI's Carlotta Ronda @rondalab.bsky.social is part of a team that developed a novel way to precisely edit the genomes of microbes in the #microbiome to defeat harmful infections. Learn more: ow.ly/taTJ50WTA7b
Reposted by Carlotta Ronda
Cool work by Carlotta Ronda, Harris Wang et al. in Nature Biomedical Engineering, Nature Portfolio
@carlottaronda.bsky.social
@harriswang.bsky.social
@natureportfolio.nature.com
www.nature.com/articles/s41...
@carlottaronda.bsky.social
@harriswang.bsky.social
@natureportfolio.nature.com
www.nature.com/articles/s41...
Precise virulence inactivation using a CRISPR-associated transposase for combating Enterobacteriaceae gut pathogens - Nature Biomedical Engineering
A self-transmissible CRISPR-associated transposase system encodes a nanobody payload to treat Shiga toxin infections.
www.nature.com
July 25, 2025 at 10:41 PM
Cool work by Carlotta Ronda, Harris Wang et al. in Nature Biomedical Engineering, Nature Portfolio
@carlottaronda.bsky.social
@harriswang.bsky.social
@natureportfolio.nature.com
www.nature.com/articles/s41...
@carlottaronda.bsky.social
@harriswang.bsky.social
@natureportfolio.nature.com
www.nature.com/articles/s41...