Clinical and Experimetal Allergy - Prof Shamji and Dr Boyle
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Clinical and Experimetal Allergy - Prof Shamji and Dr Boyle
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Clinical & Experimental Allergy (CEA) strikes a balance between clinical and scientific articles in Allergy and Immunology.
CEA is a journal of the British Society of Allergy and Clinical Immunology
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National survey exposes how allergy records are captured in hospital systems—spotlighting gaps and opportunities for safer documentation. #DrugAllergy #EHR #PatientSafety

doi.org/10.1111/cea....
Documentation of Drug and Non‐Drug Allergies in Public Hospital Electronic Health Records: A National Survey
These surveys reveal inconsistent electronic patient record (EPR) systems and poor documentation standards for non-drug allergies, leading to high incident rates and misclassification. Standardised d...
doi.org
December 12, 2025 at 3:38 PM
cea01.bsky.social
Cord blood FOXP3/TIGIT epigenetic signatures link Tregs to later food allergy risk—pointing to new early-life biomarkers. #FoodAllergy #Epigenetics #Tregs

doi.org/10.1111/cea....
A Composite Epigenetic Biomarker of FOXP3/TIGIT Correlates With Regulatory T Cell Numbers in Cord Blood and Is Associated With Subsequent Food Allergy
A composite epigenetic biomarker, denoted nTregepi, derived from cord blood DNA methylation data, correlates with the proportion of naïve regulatory T cells (nTreg) in cord blood white cells (CBWCs),...
doi.org
December 12, 2025 at 3:38 PM
cea01.bsky.social
Dupilumab blunts mucosal type 2 responses during aspirin challenge in N-ERD—highlighting its potential in complex airway disease. #NERD #Dupilumab #Type2Inflammation

doi.org/10.1111/cea....
Dupilumab Dampens Mucosal Type 2 Response During Acetylsalicylic Acid Challenge in N‐ERD Patients
Dupilumab therapy reduced elevated type 2 cytokine responses post-ASA provocation in N-ERD patients, independent of ASA tolerance, and revealed novel mechanistic insights by modulating acute type 2 i...
doi.org
December 12, 2025 at 3:37 PM
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A national ADAPT model brings structure and safety to peanut OIT for infants—supporting consistent care and better access for families. #PeanutAllergy #OralImmunotherapy #ChildHealth

doi.org/10.1111/cea....
Developing a Standardised National Model of Care for Treatment of Peanut Allergy in Infants: The ADAPT Peanut Oral Immunotherapy Program
The ADAPT OIT Program is a national initiative delivering standardised, accessible peanut oral immunotherapy to Australian infants with peanut allergy. By using a pragmatic, resource-efficient approa...
doi.org
December 12, 2025 at 3:36 PM
cea01.bsky.social
Mobile health data and virtual trial approaches unlock real-world insights on rhinitis medication results. #Rhinitis #MobileHealth #DigitalMedicine doi.org/10.1111/cea....
Assessment of the Effectiveness of Allergic Rhinitis Medications Using a Target Trial Emulation Approach Based on Mobile Health Data
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doi.org
November 12, 2025 at 3:25 PM
cea01.bsky.social
New case series on fatal food anaphylaxis—airway, breathing, and circulation failures revealed. #FoodAllergy #Anaphylaxis #EmergencyCare doi.org/10.1111/cea....
Airway, Breathing or Circulation Failure in Fatal Food Anaphylaxis: A Nationally Representative Case Series
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doi.org
November 12, 2025 at 3:24 PM
cea01.bsky.social
Mite allergy risks uncovered by population study—fresh insights for screening and prevention. #MiteAllergy #AllergyResearch #Epidemiology doi.org/10.1111/cea....
Uncovering Mite Sensitisation: Epidemiological Insights From a General Population Study
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November 12, 2025 at 3:23 PM
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Non-standard adrenaline auto-injector prescribing revealed—better guidance needed for anaphylaxis safety in England. #Anaphylaxis #PatientSafety #Prescribing doi.org/10.1111/cea....
Adrenaline Auto‐Injector Prescribing in Primary Care in England: An Analysis of Non‐Standard Dosing
Investigation into English primary care prescription data reveals that patients are receiving non-standard doses of adrenaline auto-injectors at all ages and across the whole of England. Guidance mus....
doi.org
November 12, 2025 at 3:21 PM
cea01.bsky.social
How long does urticaria last? New research on disease duration and determinants in primary care. #Urticaria #PrimaryCare #ChronicIllness doi.org/10.1111/cea....
Exploring the Disease Duration of Urticaria and Associated Determinants in Primary Care
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doi.org
November 12, 2025 at 3:10 PM
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CompITO study compares rush vs. conventional oral immunotherapy for milk and egg allergy management—find out more! #FoodAllergy #Immunotherapy #CompITO doi.org/10.1111/cea....
Comparison Between a Rush and a Conventional Oral Immunotherapy Protocol to Treat Cow's Milk and Hen's Egg Allergy. CompITO Study Methodology
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doi.org
November 12, 2025 at 3:06 PM
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Benralizumab shows strong results for severe asthma remission—real patients, real progress! #Asthma #Benralizumab #Respiratory doi.org/10.1111/cea....
Early and Sustained Asthma Control and Remission in Real‐World Patients With Severe Eosinophilic Asthma Treated With Benralizumab: XALOC‐2
Real-world patients with severe eosinophilic asthma treated with benralizumab showed early and sustained improvements in symptoms. Clinically meaningful improvements began as early as one week after ...
doi.org
November 12, 2025 at 3:04 PM
cea01.bsky.social
Elderly atopic dermatitis is rising globally—see new data on risks, disparities, and projections to 2030. #Dermatology #AtopicDermatitis #GlobalHealth doi.org/10.1111/cea....
Global Burden of Elderly Atopic Dermatitis (1990–2021) and Projections to 2030: A Socio‐Demographic Index Analysis
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doi.org
November 12, 2025 at 3:00 PM
cea01.bsky.social
China’s severe asthma landscape is changing—novel treatments and research lead better patient care! #SevereAsthma #China

doi.org/10.1111/cea....
Management and Research Progress of Severe Asthma in China
Severe asthma (SA) accounts for only 3.4%–8.3% of patients with asthma yet ~25% of China's asthma-related socioeconomic burden. Chinese guidelines, specialist training, and health policies have been ...
doi.org
November 5, 2025 at 12:23 PM
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PEN-FAST rule validated for penicillin allergy in Asia—supports safe antibiotic use and better patient care. #PenicillinAllergy #ClinicalTools

doi.org/10.1111/cea....
Validation of the PEN‐FAST Penicillin Allergy Clinical Decision Rule in an Asian Cohort
PEN-FAST ≤ 2 shows high NPV, validating it as a reliable screening tool in Asians. Direct drug provocation is safe for low-risk patients identified by PEN-FAST ≤ 2. PEN-FAST shows modest discriminati...
doi.org
November 5, 2025 at 12:22 PM
cea01.bsky.social
Drug allergy management gets a boost with a de-labelling tool—streamlining records and patient safety! #DrugAllergy #ClinicalTools

doi.org/10.1111/cea....
Managing Drug Hypersensitivities: Clinicians' Perceptions on an Optimised Documentation Tool With De‐Labelling Feature
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doi.org
November 5, 2025 at 12:21 PM
cea01.bsky.social
Type-2 inflammation markers add precision to asthma diagnosis—optimising care for diverse patients! #Asthma #Biomarkers

doi.org/10.1111/cea....
Type‐2 Biomarkers, Asthma Diagnosis and Lung Function Impairment in the General Population
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doi.org
November 5, 2025 at 12:20 PM
cea01.bsky.social
New findings help clarify how FeNO relates to bronchodilation—refining asthma diagnosis and care. #Asthma #FeNO

doi.org/10.1111/cea....
Reassessing the Relationship Between Exhaled Nitric Oxide and Acute Bronchodilation in Asthma Patients
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doi.org
November 5, 2025 at 12:20 PM
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Machine learning reveals new asthma phenotypes—driving more personalised care for patients, faster! #Asthma #MachineLearning

doi.org/10.1111/cea....
Unsupervised Machine Learning Identifies Asthma Phenotypes in the Population‐Based West Sweden Asthma Study
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doi.org
November 5, 2025 at 12:19 PM
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Long-term gene analysis shows how allergic rhinitis patients change on dust mite immunotherapy—precision insights for better allergy care! #Immunotherapy #GeneExpression

doi.org/10.1111/cea....
Longitudinal Blood Transcriptome Analysis Reveals Dynamic Gene Expression Patterns in Patients With Allergic Rhinitis Following House Dust Mite Subcutaneous Immunotherapy
AR inhibits Th1 immune responses and induces B cell activation. SCIT dynamically modulates blood gene expression gradually normalised. SCIT enhanced type I interferon responses and antiviral pathways...
doi.org
November 5, 2025 at 12:19 PM
cea01.bsky.social
Fibroblasts in the gut help fuel food allergy reactions—new nanotherapies could interrupt this process! #FoodAllergy #Immunology

doi.org/10.1111/cea....
Intestinal Fibroblasts Orchestrate IL‐4‐Driven Th2 Polarisation in Food Allergy via Paracrine Signalling and Nanotherapeutic Targeting
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doi.org
October 15, 2025 at 11:07 AM
cea01.bsky.social
Greater adherence to grass pollen immunotherapy means fewer allergy meds needed—commitment pays off! #AllergicRhinitis #Immunotherapy

doi.org/10.1111/cea....
Adherence to Grass Pollen Allergen Immunotherapy and Allergy Medication Use in Patients With Allergic Rhinitis
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doi.org
October 15, 2025 at 11:05 AM
cea01.bsky.social
Asthma medication adherence is complex—patient, system, and social factors all play a part. Let’s close the gaps! #AsthmaCare #Adherence

doi.org/10.1111/cea....
Direct and Indirect Pathways Between Patient, Health System and Socioeconomic Factors and Medication Adherence in Asthma
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doi.org
October 15, 2025 at 11:04 AM
cea01.bsky.social
Chronic urticaria management keeps progressing—remission and control rates are improving with better therapies! #Urticaria #AllergyCare

doi.org/10.1111/cea....
Temporal Trends in the Course and Management of Chronic Urticaria at a European Tertiary Center
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doi.org
October 15, 2025 at 11:02 AM
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High skin hydration in infants could signal future eczema risk—an early clue for better prevention! #AtopicDermatitis #PediatricDermatology

doi.org/10.1111/cea....
High Stratum Corneum Hydration May Predict Atopic Dermatitis Development in Moisturised Infants
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doi.org
October 15, 2025 at 11:00 AM
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Monoclonal IgG antibodies offer new hope for rapid, targeted passive allergy immunotherapy—could this transform allergy care? #Immunotherapy #AllergyResearch

doi.org/10.1111/cea....
Allergen‐Specific Human Monoclonal IgG Antibodies for Use in Passive Allergy Immunotherapy
The last decades have shown the number of subjects developing allergic rhinitis (AR), allergic asthma (AA), atopic dermatitis (AD), and food allergy rose continuously worldwide. To cure these allergi...
doi.org
October 15, 2025 at 10:58 AM