Claus Wilke
@clauswilke.com
Computational biologist, data scientist, digital artist | he, him | http://clauswilke.com/ | Opinions are my own and do not represent UT Austin.
Phase 4: Suggest alternative meeting participants based on their on-time and star ratings. "You requested a meeting with John, but John is always late. Consider asking Mike instead, he's got a 5-star rating and on average shows up one minute early."
January 12, 2026 at 9:50 PM
Phase 4: Suggest alternative meeting participants based on their on-time and star ratings. "You requested a meeting with John, but John is always late. Consider asking Mike instead, he's got a 5-star rating and on average shows up one minute early."
Reposted by Claus Wilke
Welcome to everyone joining Bluesky from twitter. Someone will be assigned to you to misunderstand one of your jokes and scream at you shortly.
January 10, 2026 at 6:43 PM
Welcome to everyone joining Bluesky from twitter. Someone will be assigned to you to misunderstand one of your jokes and scream at you shortly.
If you don't want to use Chrome but need a Chromium-based browser consider Brave. I rarely have problems with Brave on any websites, and it blocks nearly all ads also.
brave.com
brave.com
The browser that puts you first | Brave
The Brave browser is a fast, private and secure web browser for PC, Mac and mobile. Download now to enjoy a faster ad-free browsing experience that saves data and battery life by blocking tracking sof...
brave.com
January 9, 2026 at 11:10 PM
If you don't want to use Chrome but need a Chromium-based browser consider Brave. I rarely have problems with Brave on any websites, and it blocks nearly all ads also.
brave.com
brave.com
And, because you're always just one or two failed funding cycles from ruin, you're constantly asking for more money than you actually need, and then you get the grants and need to hire people, and then later you don't want to fire them, and on it goes. 2/2
December 21, 2025 at 10:05 PM
And, because you're always just one or two failed funding cycles from ruin, you're constantly asking for more money than you actually need, and then you get the grants and need to hire people, and then later you don't want to fire them, and on it goes. 2/2
I'm convinced large labs are a survival mechanism in a hypercompetitive funding environment. You need the critical mass to write the big papers that allow you to get the next round of funding. 1/2
I've often wondered why so many academic scientists want large labs (i.e., numerous graduate students, postdocs, etc).
Today it occurred to me that we learn how to run a lab from our own advisors and statistically, at least, tend model our labs on theirs.
(1/2)
Today it occurred to me that we learn how to run a lab from our own advisors and statistically, at least, tend model our labs on theirs.
(1/2)
December 21, 2025 at 10:03 PM
I'm convinced large labs are a survival mechanism in a hypercompetitive funding environment. You need the critical mass to write the big papers that allow you to get the next round of funding. 1/2
Let's not get started on pasting with styling options by default. Who ever thought that if I copy a sentence from a website I would want that sentence in the color and font it was shown originally? I'm fighting with this one feature literally every day.
December 21, 2025 at 7:57 PM
Let's not get started on pasting with styling options by default. Who ever thought that if I copy a sentence from a website I would want that sentence in the color and font it was shown originally? I'm fighting with this one feature literally every day.
Reminder that similar mistakes can easily arise in Python.
December 21, 2025 at 3:28 PM
Reminder that similar mistakes can easily arise in Python.
The range of the ID.Buzz is 258 miles. Can't road trip in it. Totally missing the mark.
December 21, 2025 at 5:46 AM
The range of the ID.Buzz is 258 miles. Can't road trip in it. Totally missing the mark.
It is 2025 and this error is still a thing. Biggest software company in the world. 🤦
December 18, 2025 at 1:00 AM
It is 2025 and this error is still a thing. Biggest software company in the world. 🤦
Become a colleague in my department!
Applications close in four days, December 15.
Applications close in four days, December 15.
My department at UT Austin is looking to hire an Assistant Professor in Evolutionary Biology, broadly defined. Feel free to reach out to me with any questions you may have.
apply.interfolio.com/177547
apply.interfolio.com/177547
Apply - Interfolio
{{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
apply.interfolio.com
December 11, 2025 at 7:15 PM
Become a colleague in my department!
Applications close in four days, December 15.
Applications close in four days, December 15.
Nice carpet on the UFO ramp. 👍
December 10, 2025 at 7:00 AM
Nice carpet on the UFO ramp. 👍
Somewhat relevant.
allscience.substack.com/p/veterinary...
allscience.substack.com/p/veterinary...
Veterinary Medicine is Becoming a Luxury Product
Aggressive pricing strategies to maximize profit jeopardize our industry
allscience.substack.com
December 7, 2025 at 8:27 PM
Somewhat relevant.
allscience.substack.com/p/veterinary...
allscience.substack.com/p/veterinary...
Go to any website, click on View -> Developer -> View Source. There you go. "code"
If you dig around a bit, you may even find javascript.
If you dig around a bit, you may even find javascript.
December 5, 2025 at 2:40 AM
Go to any website, click on View -> Developer -> View Source. There you go. "code"
If you dig around a bit, you may even find javascript.
If you dig around a bit, you may even find javascript.
Because people who take stock images can't program?
There's also this though:
There's also this though:
December 5, 2025 at 2:26 AM
Because people who take stock images can't program?
There's also this though:
There's also this though:
It will not come back automatically.
November 30, 2025 at 5:15 PM
It will not come back automatically.
I was shocked to learn that SQL does the same. Creates a lot of doubt in my mind about SQL as a suitable language for data analytics.
November 26, 2025 at 5:18 PM
I was shocked to learn that SQL does the same. Creates a lot of doubt in my mind about SQL as a suitable language for data analytics.
Reposted by Claus Wilke
Python people, please embrace missing values. I want the output with all the observations, not only the filtered ones without missing values. If I need filtering, I will do it myself.
November 26, 2025 at 8:16 AM
Python people, please embrace missing values. I want the output with all the observations, not only the filtered ones without missing values. If I need filtering, I will do it myself.
Don't forget the mRNA that Whole Foods is sneaking into all their products. The entire store is basically an mRNA store, and they don't even tell you on the labels.
November 25, 2025 at 3:53 PM
Don't forget the mRNA that Whole Foods is sneaking into all their products. The entire store is basically an mRNA store, and they don't even tell you on the labels.
Every time you read about peptides, think "molecules" instead and see if the text still makes sense:
"The internet loves therapy using molecules. Is it really a miracle cure?"
Btw, insulin is a peptide. If you're a Type I diabetic, this peptide absolutely is a miracle cure. And perfectly safe.
"The internet loves therapy using molecules. Is it really a miracle cure?"
Btw, insulin is a peptide. If you're a Type I diabetic, this peptide absolutely is a miracle cure. And perfectly safe.
November 25, 2025 at 3:34 PM
Every time you read about peptides, think "molecules" instead and see if the text still makes sense:
"The internet loves therapy using molecules. Is it really a miracle cure?"
Btw, insulin is a peptide. If you're a Type I diabetic, this peptide absolutely is a miracle cure. And perfectly safe.
"The internet loves therapy using molecules. Is it really a miracle cure?"
Btw, insulin is a peptide. If you're a Type I diabetic, this peptide absolutely is a miracle cure. And perfectly safe.
The peptide discussion highlights how little people know about chemistry. Peptides are such a huge group of chemicals treating them as one thing is absurd. Many peptides are perfectly safe. (Your food is full of peptides.) Others are toxic. Every peptide needs to be evaluated as its own thing.
"The growing popularity of these drugs [peptides]
shows that many people will experiment with them long before science confirms they work or are safe."
www.nytimes.com/2025/11/18/w...
my review erictopol.substack.com/p/the-peptid...
shows that many people will experiment with them long before science confirms they work or are safe."
www.nytimes.com/2025/11/18/w...
my review erictopol.substack.com/p/the-peptid...
The Internet Loves Peptide Therapy. Is It Really a Miracle Cure?
www.nytimes.com
November 25, 2025 at 3:34 PM
The peptide discussion highlights how little people know about chemistry. Peptides are such a huge group of chemicals treating them as one thing is absurd. Many peptides are perfectly safe. (Your food is full of peptides.) Others are toxic. Every peptide needs to be evaluated as its own thing.
The statistical test you would run in this situation to ask whether there was a difference in outcomes is called a chi-square test. And it will tell you in no uncertain terms that you can absolutely not distinguish between 17 and 21 deaths among 22,000 people. It's noise. P = 0.6267.
November 24, 2025 at 3:05 PM
The statistical test you would run in this situation to ask whether there was a difference in outcomes is called a chi-square test. And it will tell you in no uncertain terms that you can absolutely not distinguish between 17 and 21 deaths among 22,000 people. It's noise. P = 0.6267.
I know several people with dyslexia who have been quite successful in computer science and/or software engineering. I believe dyslexia often coincides with a talent for the kind of abstract thinking you need when devising complex algorithms. Unfortunately career offices don't know this.
November 24, 2025 at 2:57 AM
I know several people with dyslexia who have been quite successful in computer science and/or software engineering. I believe dyslexia often coincides with a talent for the kind of abstract thinking you need when devising complex algorithms. Unfortunately career offices don't know this.
I think there's a massive opportunity here for somebody to write the #2 pathtracer in R. 😜
November 22, 2025 at 2:55 AM
I think there's a massive opportunity here for somebody to write the #2 pathtracer in R. 😜