colleennoviello.bsky.social
@colleennoviello.bsky.social
Reposted
RFK Jr and Statistics:
May 5, 2025 at 4:06 PM
With the crazy fires all around, I neglected to highlight the incredible story, led by our post-doc Jia Zhou, on native GABA-A receptors!! Truly a heroic effort!!!
www.nature.com/articles/s41...
Resolving native GABAA receptor structures from the human brain - Nature
Cryo-electron microscopy structures of native type A GABA receptors from human brain reveal diverse subunit compositions, protein binding partners and binding sites for antiepileptic drugs.
www.nature.com
January 24, 2025 at 8:29 PM
Pretty excited about this work looking at high-resolution mechanisms involved in the autoimmune disease myasthenia gravis! Please read our pre-print :D www.biorxiv.org/content/10.1...
Autoimmune mechanisms elucidated through muscle acetylcholine receptor structures
Skeletal muscle contraction is mediated by acetylcholine (ACh) binding to its ionotropic receptors (AChRs) at neuromuscular junctions. In myasthenia gravis (MG), autoantibodies target AChRs, disruptin...
www.biorxiv.org
December 21, 2024 at 7:30 PM
Reposted
November 21, 2024 at 12:55 PM