CortésLab
@corteslab.bsky.social
87 followers 180 following 11 posts
We study DNA topology, the action of topoisomerses and DNA break repair to understand genome organization, dynamics and stability @cniostopcancer.bsky.social https://repairome.bioinfo.cnio.es
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corteslab.bsky.social
Looking forward to reading that!
Reposted by CortésLab
ramsdenlab.bsky.social
Also: Research positions in the Ramsden lab. Post doctoral position - 5 years funding available. Cross-country collaborative, working closely with the groups of Gupta, Rothenberg, Wood, and Doublie.
Some example pubs from the last two post docs: PMIDs 37968395,35927262, 2963245, 30213916, 26240371
corteslab.bsky.social
In this screen the system is blind to HR. Repeating with an homologous template is in the pipeline.
Muchas gracias! 😘
corteslab.bsky.social
Thanks a lot Benjamin. Glad you like it!
corteslab.bsky.social
Thanks Iván! I also hope so 😀
corteslab.bsky.social
Thanks so much, Juanma! Excited to discuss the paper in a couple of weeks at the Social DNAing Webinar Series. Grateful for the invitation!
corteslab.bsky.social
Thanks Nuria! Hope it's a useful resource for the cancer genomics field
corteslab.bsky.social
Check out our web tool to see interactive networks of DSB repair genes, browse your gene of interest for its contribution to DSB repair profiles and analyze functional relationships based on similarities in repair patterns

Enjoy!!!

repairome.bioinfo.cnio.es
REPAIRome
repairome.bioinfo.cnio.es
corteslab.bsky.social
Congratulations to all the people involved, also in
Ana Losada's
@rfleiro.bsky.social
@gmaci.bsky.social
labs
@cniostopcancer.bsky.social

Specially leading authors
Ernesto López de Alba
@israelsalguero.bsky.social
Daniel Giménez Llorente

Very proud of you!!!
corteslab.bsky.social
We provide:
- A catalog of how more than 18K genes affect DSB repair sequence outcomes induced by CRISPR-Cas9
- Examples of how it can be used at different levels, from identifying novel factors and functional relationships, to explaining mutational signatures in cancer