Cardiovascular Research Cluster (CVRC)
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cvrcbern.bsky.social
Cardiovascular Research Cluster (CVRC)
@cvrcbern.bsky.social
70 followers 110 following 110 posts
Cardiovascular Scientists & Clinicians at the University of Bern, Inselspital University Hosp., and/or the Swiss Inst. for Transl. & Entrep. Med. (sitem-insel)
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cvrcbern.bsky.social
New publication: The Heart That Took the Scenic Route: Europe’s Record-Breaking 9-Hours OCS Journey. Congratulationa to the authors!
pubmed.ncbi.nlm.nih.gov/41051264/
#CVRCBern
The heart that took the scenic route: Europe's record-breaking 9-hours OCS journey - PubMed
We report Europe's longest documented heart perfusion using the Transmedics Organ Care System (OCS) during a heart transplantation. A 55-year-old patient with end-stage heart failure received a donor heart after 536 min (8 h 55 min) of OCS perfusion and a total out-of-body time of 676 min (11 h 16 m …
pubmed.ncbi.nlm.nih.gov
January 6, 2026 at 10:13 AM
cvrcbern.bsky.social
New publication: Use of a large-area focal lattice-tip catheter for cavotricuspid isthmus ablation. Congratulations to the authors!
pubmed.ncbi.nlm.nih.gov/41067476/
#CVRCBern
Use of a large-area focal lattice-tip catheter for cavotricuspid isthmus ablation - PubMed
Use of a large-area focal lattice-tip catheter for cavotricuspid isthmus ablation
pubmed.ncbi.nlm.nih.gov
December 18, 2025 at 11:39 AM
cvrcbern.bsky.social
New publication: Multimodal Machine Learning-Based Technical Failure Prediction in Patients Undergoing Transcatheter Aortic Valve Replacement. Congratulations to the authors!
pubmed.ncbi.nlm.nih.gov/40972358/
#CVRCBern
Multimodal Machine Learning-Based Technical Failure Prediction in Patients Undergoing Transcatheter Aortic Valve Replacement - PubMed
Machine learning-based models that integrate multimodal data can effectively predict VARC-3 technical failure in TAVR, refining patient selection and optimizing procedural strategies.
pubmed.ncbi.nlm.nih.gov
December 17, 2025 at 11:33 AM
Reposted by Cardiovascular Research Cluster (CVRC)
dbmr-unibe.bsky.social
The call for applications for the Johanna Dürmüller-Bol DBMR Research Award is now open. ✍️ Apply until March 26 ➡️ tinyurl.com/yj65abu9 @medfacultyunibe.bsky.social @unibe.ch
December 17, 2025 at 10:35 AM
cvrcbern.bsky.social
New publication: European Society of Cardiology clinical consensus statement on obesity and cardiovascular disease: 10 key points. Congratulations to the authors!
pubmed.ncbi.nlm.nih.gov/40838297/
#CVRCBern
European Society of Cardiology clinical consensus statement on obesity and cardiovascular disease: 10 key points - PubMed
European Society of Cardiology clinical consensus statement on obesity and cardiovascular disease: 10 key points
pubmed.ncbi.nlm.nih.gov
December 15, 2025 at 7:28 AM
cvrcbern.bsky.social
New publication: Total aortic arch replacement using frozen elephant trunk: the beating-heart technique. Congratulations to the authors! pubmed.ncbi.nlm.nih.gov/41099001/
#CVRCBern
Total aortic arch replacement using frozen elephant trunk: the beating-heart technique - PubMed
Total aortic arch replacement using frozen elephant trunk: the beating-heart technique
pubmed.ncbi.nlm.nih.gov
December 11, 2025 at 8:03 AM
Reposted by Cardiovascular Research Cluster (CVRC)
ishlt.bsky.social
📢 Registration for #ISHLT2026 is NOW OPEN! Join your global, multidisciplinary colleagues in Toronto.
✨ New this year: you can book your hotel at exclusive room rates while registering. ➡️ Register by 4 February 📅 to qualify for the early registration fee: 🔗 bit.ly/4aFzxTd

#TransplantSky #MedSky
December 10, 2025 at 6:31 PM
cvrcbern.bsky.social
New publication: In vivo imaging of the barrier properties of the glia limitans during health and neuroinflammation. Congratulations to the authors!
pubmed.ncbi.nlm.nih.gov/41057305/
#CVRCBern
In vivo imaging of the barrier properties of the glia limitans during health and neuroinflammation - PubMed
The glia limitans ensheathes the entire central nervous system (CNS) parenchyma towards the outer surfaces and the perivascular spaces and is formed by a subset of astrocytes strategically localized at these outer parenchymal borders. Barrier properties of the glia limitans during health and neuroin …
pubmed.ncbi.nlm.nih.gov
December 10, 2025 at 11:09 AM
cvrcbern.bsky.social
New publication: Chemokine–receptor-guided B-cell immunity in cardiovascular disease. Congratulations to the authors!
pubmed.ncbi.nlm.nih.gov/40986007/
#CVRCBern
Chemokine-receptor-guided B-cell immunity in cardiovascular disease - PubMed
Cardiovascular diseases (CVD) include a wide range of disorders affecting the heart and blood vessels, many of which are associated with atherosclerosis. Atherosclerosis is the main underlying cause of CVDs and represents a chronic inflammatory disease of the large arteries involving the build-up of …
pubmed.ncbi.nlm.nih.gov
December 9, 2025 at 9:55 AM
cvrcbern.bsky.social
New publication: Percutaneous Left Atrial Appendage Closure in Patients With Cardioembolic Breakthrough Stroke: An International Observational Study. Congratulations to the authors! pubmed.ncbi.nlm.nih.gov/40985135/
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Percutaneous Left Atrial Appendage Closure in Patients With Cardioembolic Breakthrough Stroke: An International Observational Study - PubMed
LAAC procedures were safe and feasible in patients with cardioembolic breakthrough stroke. Recurrent stroke rates were lower than those reported in previous studies with OAC continuation after breakthrough stroke, suggesting a potential additive protection by LAAC on top of OAC. Results from ongoing …
pubmed.ncbi.nlm.nih.gov
December 8, 2025 at 10:28 AM
cvrcbern.bsky.social
New publication: Impact of alternative efficacy end point definitions on reported outcomes after ablation of paroxysmal atrial fibrillation – Insights from the COMPARE-CRYO study using continuous rhythm monitoring. Congratulations to the authors!
pubmed.ncbi.nlm.nih.gov/40976542/
#CVRCBern
Impact of alternative efficacy end point definitions on reported outcomes after ablation of paroxysmal atrial fibrillation - Insights from the COMPARE-CRYO study using continuous rhythm monitoring - PubMed
Alternative efficacy end point definitions have a significant impact on reported outcomes and health care utilization metrics after AF ablation. These findings are important when considering end point definitions other than the traditional 30 seconds in the design of future AF-ablation trials.
pubmed.ncbi.nlm.nih.gov
December 3, 2025 at 3:47 PM
cvrcbern.bsky.social
New publication: Left Atrial Appendage Closure in Patients Refusing Oral Anticoagulation: The LAAC‐REFUSAL Study. Congratulation to the authors! pubmed.ncbi.nlm.nih.gov/40996042/
#CVRCBern
Left Atrial Appendage Closure in Patients Refusing Oral Anticoagulation: The LAAC-REFUSAL Study - PubMed
In this multicenter cohort of consecutive patients with atrial fibrillation submitted to LAAC, OAC refusal appeared as an infrequent indication. In this subgroup, LAAC was confirmed to be feasible and safe. The ischemic outcomes rates at 3 years are promising. Further studies are needed to better un …
pubmed.ncbi.nlm.nih.gov
December 2, 2025 at 7:27 AM
cvrcbern.bsky.social
New publication: Self-expanding versus balloon-expandable transcatheter heart valves in patients with excessive aortic valve cusp calcification. Congratulations to the authors! pubmed.ncbi.nlm.nih.gov/40975195/
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Self-expanding versus balloon-expandable transcatheter heart valves in patients with excessive aortic valve cusp calcification - PubMed
gov. NCT01368250.
pubmed.ncbi.nlm.nih.gov
November 25, 2025 at 7:52 AM
cvrcbern.bsky.social
New publication: Freestyle master's swimming: Nationality, sex, and performance trends in World Aquatics competitions (1986-2024). Congratulations to the authors!
pubmed.ncbi.nlm.nih.gov/40929232/
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Freestyle master's swimming: Nationality, sex, and performance trends in World Aquatics competitions (1986-2024) - PubMed
The USA demonstrates quantitative dominance by contributing the greatest number of top 10 performers. Additionally, the study highlights significant sex-based performance differences, with males generally outperforming females in all age categories. This study comprehensively analyzes the performanc …
pubmed.ncbi.nlm.nih.gov
November 24, 2025 at 1:10 PM
cvrcbern.bsky.social
New publication: International Multicentre Study on the Treatment of Infrarenal Penetrating Aortic Ulcers. Congratulations to the authors!
pubmed.ncbi.nlm.nih.gov/40930394/
#CVRCBern
International Multicentre Study on the Treatment of Infrarenal Penetrating Aortic Ulcers - PubMed
Endovascular repair, especially with bifurcated grafts, was the preferred safe approach. CERAB and BESGs were effective in anatomically suitable cases.
pubmed.ncbi.nlm.nih.gov
November 18, 2025 at 8:11 AM
cvrcbern.bsky.social
New publication: Beyond the learning curve: How operator experience affects pulsed-field ablation outcomes. Congratulations to the authors!
pubmed.ncbi.nlm.nih.gov/40914492/
#CVRCBern
Beyond the learning curve: How operator experience affects pulsed-field ablation outcomes - PubMed
Although the learning curve for "single-shot" PFA is approximately 20 cases per operator based on procedure and fluoroscopy times, improvements in long-term PVI durability were observed after 60 cases. No difference in freedom from arrhythmia was observed during the learning curve or by using 3D-EAM …
pubmed.ncbi.nlm.nih.gov
November 13, 2025 at 9:55 AM
Reposted by Cardiovascular Research Cluster (CVRC)
ishlt.bsky.social
#ISHLT and the @sts.org will host a joint #LungTransplant Symposium at #STS2026. 🫁

📆 29 January | New Orleans, LA USA
✅ CME credits available
🎟️ One-day passes available for those who want to attend the symposium only!

Learn more & register at 🔗 bit.ly/3WKcyyr

#TransplantSky
November 10, 2025 at 3:40 PM
cvrcbern.bsky.social
New publication: Benign Metastasizing Leiomyoma Presenting as a Right Ventricular Mass. Congratulations to the authors!
pubmed.ncbi.nlm.nih.gov/40912858/
#CVRCBern
Benign Metastasizing Leiomyoma Presenting as a Right Ventricular Mass - PubMed
BML, though rare, can cause life-threatening cardiac involvement. Clinicians should consider a comprehensive cardiac evaluation for patients with unexplained cardiac symptoms and a history of leiomyoma.
pubmed.ncbi.nlm.nih.gov
November 11, 2025 at 8:12 AM
cvrcbern.bsky.social
New publication: Beneficial action potential duration–shortening effects, but deleterious negative inotropism of IKs-activator docosahexaenoyl glycine in long QT syndrome type 2. Congratulations to the authors!
pubmed.ncbi.nlm.nih.gov/40794559/
#CVRCBern
Beneficial action potential duration-shortening effects, but deleterious negative inotropism of IKs-activator docosahexaenoyl glycine in long QT syndrome type 2 - PubMed
DHA-gly-induced IKs enhancement shows promising results in shortening APD/QT in LQT2 rabbits, while having no effect on LQT1 (impaired IKs). However, its adverse effect on cardiac contractility, even in LQT1, makes it unsuitable to treat LQTS patients. Our study highlights the importance of consider …
pubmed.ncbi.nlm.nih.gov
November 5, 2025 at 12:42 PM
Reposted by Cardiovascular Research Cluster (CVRC)
lifesciswitzerland.bsky.social
🫀 Last chance to submit your abstract!
The LS² Cardiovascular Research Meeting 2026 is taking place on 13-14 January 2026, University of Bern (UniS)Join us for talks, posters, networking & dinner!

⏰ Deadlines:
Abstracts: 09 Nov 2025
Registration: 12 Dec 2025: meetings.ls2.ch/cardiovascul...
November 5, 2025 at 12:33 PM
cvrcbern.bsky.social
New publication: Influence of valve size on the hemodynamic performance of a tissue-engineered valved conduit in pulmonary position. Congratulations to the authors!
pubmed.ncbi.nlm.nih.gov/40933811/
#CVRCBern
Influence of valve size on the hemodynamic performance of a tissue-engineered valved conduit in pulmonary position - PubMed
This work provides the first <i>in-vitro</i> experimental assessment of the XPV valve, along with an exploration of how valve size affects its hemodynamic performance. Results confirm that for a given hemodynamic condition, larger valves exhibit better performance showing lower flow velocities, <i>T</i> …
pubmed.ncbi.nlm.nih.gov
November 3, 2025 at 10:32 AM
Reposted by Cardiovascular Research Cluster (CVRC)
dbmr-unibe.bsky.social
🎉 We are delighted to announce that @mosterwalder.bsky.social, research group leader in the cardiovascular (CVD) program, has been awarded the venia docendi (habilitation) for his research on Developmental Biology. 👉 tinyurl.com/28r7da55 @medfacultyunibe.bsky.social
October 14, 2025 at 2:25 PM
Reposted by Cardiovascular Research Cluster (CVRC)
snsf.ch
#Call for Postdoc.Mobility. Expand your #research experience with a stay abroad. If you would like to find out more about this call, take part in our online information event on 17. November 2025.

➡️ sohub.io/51a4
🗓️Submission deadline: 3 February 2026
November 3, 2025 at 8:00 AM
cvrcbern.bsky.social
New publication: Impact of alirocumab on neoatherosclerosis formation and vessel healing after drug-eluting stent implantation in patients with acute myocardial infarction: a substudy of the PACMAN-AMI trial. Congratulations to the authors!
pubmed.ncbi.nlm.nih.gov/40824411/
#CVRCBern
Impact of alirocumab on neoatherosclerosis formation and vessel healing after drug-eluting stent implantation in patients with acute myocardial infarction: a substudy of the PACMAN-AMI trial - PubMed
Higher on-treatment levels of low-density lipoprotein cholesterol in statin-treated patients were reportedly associated with the occurrence of neoatherosclerosis after drug-eluting stent (DES) implantation. We aimed to investigate the impact of alirocumab added to high-intensity statin therapy on ne …
pubmed.ncbi.nlm.nih.gov
October 28, 2025 at 11:23 AM
cvrcbern.bsky.social
The Cardiovascular Research Cluster Bern (CVRC) Celebrates its 10th Anniversary!!

Check out the Event Summary in our website www.cvrc.unibe.ch/about_us/cvr...

#CVRCBern
October 27, 2025 at 9:41 AM