Doris Wang
@doriswang.bsky.social
Neurosurgeon-scientist studying how brains walk the walk.
Neural interfaces, devices, oscillations, and toddler chase dynamics.
Balancing beta bursts and bedtime stories.
πUCSF | π§ β‘οΈπΆπ»ββοΈ | Views my own (but likely statistically significant)
Neural interfaces, devices, oscillations, and toddler chase dynamics.
Balancing beta bursts and bedtime stories.
πUCSF | π§ β‘οΈπΆπ»ββοΈ | Views my own (but likely statistically significant)
Reposted by Doris Wang
High-intensity focused ultrasound (HIFU) is an incision-less surgical procedure used to treat essential tremor by lesioning the brain pathway involved with tremor generation. @ucsfhealth.bsky.social neurosurgeon @doriswang.bsky.social explains that this leads to lasting tremor reduction.
September 17, 2025 at 7:12 PM
High-intensity focused ultrasound (HIFU) is an incision-less surgical procedure used to treat essential tremor by lesioning the brain pathway involved with tremor generation. @ucsfhealth.bsky.social neurosurgeon @doriswang.bsky.social explains that this leads to lasting tremor reduction.
Great talks and even more interesting and engaging discussion! Fantastic start to the think tank!
DBS Think Tank Scientific Sessions start on zoom at 1:00PM as soon as Nobel Laurette Stanley Prusiner finishes his talk and takes questions.
We are off to a great start. Here are the first two sessions for today in case you are interested in listening in. @sfn.org @parkinsondotorg.bsky.social
We are off to a great start. Here are the first two sessions for today in case you are interested in listening in. @sfn.org @parkinsondotorg.bsky.social
September 3, 2025 at 4:13 AM
Great talks and even more interesting and engaging discussion! Fantastic start to the think tank!
Congratulations!!!!!ππΎπ
August 22, 2025 at 10:42 PM
Congratulations!!!!!ππΎπ
This work was led by the amazing former postdoc Ken Louie, and an all star research team and collaborators to make it happen! #aDBS #Parkinsons #gait
August 22, 2025 at 4:25 AM
This work was led by the amazing former postdoc Ken Louie, and an all star research team and collaborators to make it happen! #aDBS #Parkinsons #gait
We tested the effects of adaptive DBS both in clinic and at home and found that aDBS improves gait symmetry and variability in patients with Parkinsonβs disease! Providing an exciting and promising therapy to restore gait functions.
August 22, 2025 at 4:22 AM
We tested the effects of adaptive DBS both in clinic and at home and found that aDBS improves gait symmetry and variability in patients with Parkinsonβs disease! Providing an exciting and promising therapy to restore gait functions.
Here, we use chronically implanted bidirectional DBS devices connected to pallidal leads and cortical ECoG strips to 1) capture biomarkers of leg swing during natural walking 2) use these biomarkers to rapidly change stimulation amplitudes during each gait cycle in an embedded device.
August 22, 2025 at 4:20 AM
Here, we use chronically implanted bidirectional DBS devices connected to pallidal leads and cortical ECoG strips to 1) capture biomarkers of leg swing during natural walking 2) use these biomarkers to rapidly change stimulation amplitudes during each gait cycle in an embedded device.
Thanks you so much for inviting me to be a part of this fantastic conference! I learned so much and am beyond excited for our field!
Day 1 of the π§ Neuroscience of the Everyday World Conference included talks from notable researchers and industry experts from around the world, discussing topics of #neuroprosthetics #neuromodulation and #neurotechnology.
July 29, 2025 at 7:50 PM
Thanks you so much for inviting me to be a part of this fantastic conference! I learned so much and am beyond excited for our field!
Reposted by Doris Wang
Weβre honored to be named among the top two neurosurgery programs nationwide and the Best in the West by @usnews.com! π It's a privilege caring for our patients and their families, and we thank our entire team for hard work and dedication. @ucsfhealth.bsky.social www.ucsfhealth.org/lp/us-news-2...
July 29, 2025 at 6:20 PM
Weβre honored to be named among the top two neurosurgery programs nationwide and the Best in the West by @usnews.com! π It's a privilege caring for our patients and their families, and we thank our entire team for hard work and dedication. @ucsfhealth.bsky.social www.ucsfhealth.org/lp/us-news-2...
Reposted by Doris Wang
A new study led by @doriswang.bsky.social's lab developed a systematic way to quantify key aspects of gait in patients with #Parkinsons and used machine learning to identify personalized deep brain stimulation (DBS) settings to improve walking: www.ucsf.edu/news/2025/07...
@ucsfhealth.bsky.social π§ π
@ucsfhealth.bsky.social π§ π
July 23, 2025 at 9:26 PM
A new study led by @doriswang.bsky.social's lab developed a systematic way to quantify key aspects of gait in patients with #Parkinsons and used machine learning to identify personalized deep brain stimulation (DBS) settings to improve walking: www.ucsf.edu/news/2025/07...
@ucsfhealth.bsky.social π§ π
@ucsfhealth.bsky.social π§ π
Lab party! Thanks to all these amazing, hardworking, compassionate geniuses for making science fun!
July 1, 2025 at 5:46 AM
Lab party! Thanks to all these amazing, hardworking, compassionate geniuses for making science fun!
Reposted by Doris Wang
Can we reboot walking after Parkinson's disease DBS?
Can AI teach deep brain stimulation devices to help people 'walk the walk?' A new study by Wang says MAYBE. Using personalized data-driven models, they optimized DBS for walking.
@parkinsondotorg.bsky.social #parkinson @ucsfhealth.bsky.social
Can AI teach deep brain stimulation devices to help people 'walk the walk?' A new study by Wang says MAYBE. Using personalized data-driven models, they optimized DBS for walking.
@parkinsondotorg.bsky.social #parkinson @ucsfhealth.bsky.social
June 28, 2025 at 1:13 PM
Can we reboot walking after Parkinson's disease DBS?
Can AI teach deep brain stimulation devices to help people 'walk the walk?' A new study by Wang says MAYBE. Using personalized data-driven models, they optimized DBS for walking.
@parkinsondotorg.bsky.social #parkinson @ucsfhealth.bsky.social
Can AI teach deep brain stimulation devices to help people 'walk the walk?' A new study by Wang says MAYBE. Using personalized data-driven models, they optimized DBS for walking.
@parkinsondotorg.bsky.social #parkinson @ucsfhealth.bsky.social
Very excited to share our newest publication on identifying neurophysiological signatures of improved gait using bidirectional DBS devices!
New in npj Parkinson's Disease, @doriswang.bsky.social's lab presents an AI approach for identifying personalized deep brain stimulation (DBS) settings to improve walking. The findings lay the groundwork for adaptive DBS systems that adjust in real-time: www.nature.com/articles/s41...
π§ π π§ͺ
π§ π π§ͺ
June 30, 2025 at 3:29 PM
Very excited to share our newest publication on identifying neurophysiological signatures of improved gait using bidirectional DBS devices!
Reposted by Doris Wang
Interested in human brain function and neuroimaging during natural real-world activities? Learn more from our amazing speakers and present your own work at the Neuroscience of the Everyday World Conference. Registration & abstract submission is now open: neuroscienceeverydayworld.org/conference-2...
March 31, 2025 at 3:18 PM
Interested in human brain function and neuroimaging during natural real-world activities? Learn more from our amazing speakers and present your own work at the Neuroscience of the Everyday World Conference. Registration & abstract submission is now open: neuroscienceeverydayworld.org/conference-2...
Reposted by Doris Wang
Very much looking forward to our speakers: @maryamshanechi.bsky.social, @hugospiers.bsky.social, Marom Bikson, @jenpitt.bsky.social, Mary Czerwinski, @peabody124.bsky.social, @dpferris.bsky.social, @sladouce.bsky.social, Matthew Rizzo,
@c-rothkopf.bsky.social, @doriswang.bsky.social, Ying Choon Wu
@c-rothkopf.bsky.social, @doriswang.bsky.social, Ying Choon Wu
March 31, 2025 at 3:37 PM
Very much looking forward to our speakers: @maryamshanechi.bsky.social, @hugospiers.bsky.social, Marom Bikson, @jenpitt.bsky.social, Mary Czerwinski, @peabody124.bsky.social, @dpferris.bsky.social, @sladouce.bsky.social, Matthew Rizzo,
@c-rothkopf.bsky.social, @doriswang.bsky.social, Ying Choon Wu
@c-rothkopf.bsky.social, @doriswang.bsky.social, Ying Choon Wu
Very excited to share our latest preprint. Using implanted DBS devices with at home wearable monitors, we were able to identify gait state in the natural environment based on cortical and basal ganglia neural signature: www.medrxiv.org/content/10.1...
At-Home Movement State Classification Using Totally Implantable Bidirectional Cortical-Basal Ganglia Neural Interface
Movement decoding from invasive human recordings typically relies on a distributed system employing advanced machine learning algorithms programmed into an external computer for state classification. ...
www.medrxiv.org
February 25, 2025 at 7:43 PM
Very excited to share our latest preprint. Using implanted DBS devices with at home wearable monitors, we were able to identify gait state in the natural environment based on cortical and basal ganglia neural signature: www.medrxiv.org/content/10.1...
To the stranger who paid for our lunch at Kona airport because I didnβt have a credit card on me (getting too used to tap to pay), thank you from the bottom of my heart and my toddlersβ growling stomachs. I will always remember your kindness and pay it forward! #humanity #payitforward #kindness
January 25, 2025 at 8:38 AM
To the stranger who paid for our lunch at Kona airport because I didnβt have a credit card on me (getting too used to tap to pay), thank you from the bottom of my heart and my toddlersβ growling stomachs. I will always remember your kindness and pay it forward! #humanity #payitforward #kindness
It suggests that abnormal pallidal outflow and synchronization between the pallidum and motor cortices may be a pathophysiological mechanism underlying disordered postural response in Parkinson's disease.
December 15, 2024 at 3:38 AM
It suggests that abnormal pallidal outflow and synchronization between the pallidum and motor cortices may be a pathophysiological mechanism underlying disordered postural response in Parkinson's disease.
Our results provide evidence for a model where synchronized premotor and motor cortical activities transiently couple with the globus pallidus to regulate the timing of postural responses, and local pallidal activity regulate the amplitude of postural changes during gait initiation.
December 15, 2024 at 3:38 AM
Our results provide evidence for a model where synchronized premotor and motor cortical activities transiently couple with the globus pallidus to regulate the timing of postural responses, and local pallidal activity regulate the amplitude of postural changes during gait initiation.
We found distinct patterns of oscillatory changes that occur in the pallidum and motor cortex, and found that while pallidum gamma power is predictive of the scaling of gait initiation, pallidal M1, and premotor-M1 low frequency coherence is predictive of the timing of weight shift
December 15, 2024 at 3:36 AM
We found distinct patterns of oscillatory changes that occur in the pallidum and motor cortex, and found that while pallidum gamma power is predictive of the scaling of gait initiation, pallidal M1, and premotor-M1 low frequency coherence is predictive of the timing of weight shift
Excited to share our new preprint. We recorded field potentials from the motor/premotor cortices and pallidum of people with Parkinsonβs disease as they performed a gait initiation task to understand the cortico-pallidal network dynamics that underlie this action: www.medrxiv.org/content/10.1...
Pallidal and motor cortical interactions determine gait initiation dynamics in Parkinson's disease
Gait initiation is a fundamental human task, requiring one or more anticipatory postural adjustments (APA) prior to stepping. Deviations in amplitude and timing of APAs exist in Parkinson's disease (P...
www.medrxiv.org
December 15, 2024 at 3:33 AM
Excited to share our new preprint. We recorded field potentials from the motor/premotor cortices and pallidum of people with Parkinsonβs disease as they performed a gait initiation task to understand the cortico-pallidal network dynamics that underlie this action: www.medrxiv.org/content/10.1...
Completed our 100th focused ultrasound treatment! It truly takes a village and a collaborative effort to make it possible. Go team and hereβs to many more!
#fus #hifu #neurosurgery #tremor
#fus #hifu #neurosurgery #tremor
December 14, 2024 at 2:21 PM
Completed our 100th focused ultrasound treatment! It truly takes a village and a collaborative effort to make it possible. Go team and hereβs to many more!
#fus #hifu #neurosurgery #tremor
#fus #hifu #neurosurgery #tremor
Masters debate in a chateau! Amazing talks, colleagues, and inspiring innovation. So great to be back in Paris even just for a day!
December 4, 2024 at 4:58 PM
Masters debate in a chateau! Amazing talks, colleagues, and inspiring innovation. So great to be back in Paris even just for a day!
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December 1, 2024 at 10:11 PM
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