Doudou Yu
@doudouyu.bsky.social
Pinned
Doudou Yu
@doudouyu.bsky.social
· Oct 10
HypoAD: volumetric and single-cell analysis reveals changes in the human hypothalamus in aging and Alzheimer's disease
Alterations in metabolism, stress response, sleep, circadian rhythms, and neuroendocrine processes are key features of aging and neurodegeneration. These fundamental processes are regulated by the hyp...
www.biorxiv.org
Sleep, diet, and stress regulation are key to healthy aging but often decline early.
We investigated how the hypothalamus, the brain's control center for these functions, changes during normal aging and in Alzheimer's disease (AD).
Checkout our HypoAD story 🧵:
www.biorxiv.org/content/10.1...
We investigated how the hypothalamus, the brain's control center for these functions, changes during normal aging and in Alzheimer's disease (AD).
Checkout our HypoAD story 🧵:
www.biorxiv.org/content/10.1...
Sleep, diet, and stress regulation are key to healthy aging but often decline early.
We investigated how the hypothalamus, the brain's control center for these functions, changes during normal aging and in Alzheimer's disease (AD).
Checkout our HypoAD story 🧵:
www.biorxiv.org/content/10.1...
We investigated how the hypothalamus, the brain's control center for these functions, changes during normal aging and in Alzheimer's disease (AD).
Checkout our HypoAD story 🧵:
www.biorxiv.org/content/10.1...
HypoAD: volumetric and single-cell analysis reveals changes in the human hypothalamus in aging and Alzheimer's disease
Alterations in metabolism, stress response, sleep, circadian rhythms, and neuroendocrine processes are key features of aging and neurodegeneration. These fundamental processes are regulated by the hyp...
www.biorxiv.org
October 10, 2025 at 9:25 PM
Sleep, diet, and stress regulation are key to healthy aging but often decline early.
We investigated how the hypothalamus, the brain's control center for these functions, changes during normal aging and in Alzheimer's disease (AD).
Checkout our HypoAD story 🧵:
www.biorxiv.org/content/10.1...
We investigated how the hypothalamus, the brain's control center for these functions, changes during normal aging and in Alzheimer's disease (AD).
Checkout our HypoAD story 🧵:
www.biorxiv.org/content/10.1...
Reposted by Doudou Yu
Congratulations to @brunetlab.bsky.social on election to the American Academy of Arts and Sciences!
April 23, 2025 at 11:58 PM
Congratulations to @brunetlab.bsky.social on election to the American Academy of Arts and Sciences!
Reposted by Doudou Yu
Male-Female comparisons are powerful in Biomedical Research. More on this and what is a "Pink Box Warning"?? From @ctmurphy1.bsky.social @bbparis1984.bsky.social Yousin Suh and me in the latest issue of Neuron www.sciencedirect.com/science/arti...
Biological sex matters in brain aging
Every cell in the body has a biological sex. The expansion of aging research to investigate female- and male-specific biology heralds a major advance …
www.sciencedirect.com
January 8, 2025 at 4:38 PM
Male-Female comparisons are powerful in Biomedical Research. More on this and what is a "Pink Box Warning"?? From @ctmurphy1.bsky.social @bbparis1984.bsky.social Yousin Suh and me in the latest issue of Neuron www.sciencedirect.com/science/arti...