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drcarolw.bsky.social
Carol Wilkinson
@drcarolw.bsky.social
730 followers 520 following 25 posts
Developmental Behavioral Pediatrician at Boston Children’s, Neuroscientist. Interested in cognition and language in the context of neurodevelopment. End goal - helping kids thrive.
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Reposted by Carol Wilkinson
laurelgd.bsky.social
Laurel Joy Gabard-Durnam @laurelgd.bsky.social · Jul 29
thrilled to share this project over a decade in the making out now in @pnas.org! We show that precocious GABA boosting in neonates by early sevoflurane/propofol anesthetic exposure accelerates visual cortical maturation in human infants
www.pnas.org/doi/10.1073/...
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
www.pnas.org
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drcarolw.bsky.social
Carol Wilkinson @drcarolw.bsky.social · Jun 9
We are hiring a Spanish-speaking research assistant for our Baby Steps Study - great opportunity for a pre-med or pre-grad postbac interested in working in the area of child neurodevelopment. Please share! jobs.bostonchildrens.org/job/22060807...
Clinical Research Assistant I- Baby Steps
Careers at Boston Children’s Hospital will help you reach your goals – both in and out of the workplace.
jobs.bostonchildrens.org
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Reposted by Carol Wilkinson
jeremymberg.bsky.social
Jeremy Berg @jeremymberg.bsky.social · Apr 21
NIH just posted a Notice with the new Terms and Conditions...

grants.nih.gov/grants/guide...
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Carol Wilkinson @drcarolw.bsky.social · Feb 17
Please share: Opportunity for soon to be graduating grad students with an interest in neurodevelopment and mental health - our T32 postdoc program in neurodevelopmental disorders at Boston Children’s is accepting applications: rsztnc.org/wp-content/u...
rsztnc.org
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Carol Wilkinson @drcarolw.bsky.social · Feb 4
Check out this paper! @ccclements.bsky.social dug deep into understanding EEG differences in Tuberous Sclerosis and teasing apart effects of seizures and seizure meds on EEG power spectra. Important implications for EEG use in clinical trials. What a fun collaboration!
ccclements.bsky.social
Caitlin C Clements @ccclements.bsky.social · Feb 3
New paper alert! A story where secondary findings were perhaps more interesting than our original question. rdcu.be/d6LnQ Before I start, I extend deep thanks to the families in the study. 🧵 1/x
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Carol Wilkinson @drcarolw.bsky.social · Jan 9
As always - huge thanks to the many many families who participated and the research staff and students who collected data over the years. Excited about our next steps.
drcarolw.bsky.social
Carol Wilkinson @drcarolw.bsky.social · Jan 9
We tested this in toddlers with autism or Down syndrome and found significant reductions in brain age estimates compared to chronological age. Differences in Down syndrome were more striking across the age range. More work needed to determine the clinical utility of this method!
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Carol Wilkinson @drcarolw.bsky.social · Jan 9
Next we hypothesized that infants/toddlers with altered development would have increased prediction errors. This is described as a brain-age gap and could be used to identify children with altered brain development before they show delays.
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Carol Wilkinson @drcarolw.bsky.social · Jan 9
Winko used an innovative approach combining Shapley values and hierarchical clustering to assess feature importance which identified periodic alpha and beta band power as the strongest predictors of age.
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Carol Wilkinson @drcarolw.bsky.social · Jan 9
We leveraged almost 1000s EEGs collected in infants with typical development ranging from 2-38 months old to develop age prediction models, with the best model predicting age within 92 days – not too shabby.
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Carol Wilkinson @drcarolw.bsky.social · Jan 9
New EEG paper! Amazing work by Winko An utilizing the incredible data collected across many years in Chuck Nelson’s lab.
doi.org/10.1016/j.dc...
EEG-based brain age prediction in infants-toddlers: Implication for early detection of neurodevelopmental disorders.
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Carol Wilkinson @drcarolw.bsky.social · Jan 6
Beautiful gift from Megan Tsou - an amazing study coordinator in the lab. Love love love it!
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Carol Wilkinson @drcarolw.bsky.social · Dec 20
Actually there was a #4! It’s also about fit. Apply to schools that align with your interests. Schools care about being able to successfully support your growth. So if they don’t think they can do that, they aren’t going to accept you.

Good luck!
drcarolw.bsky.social
Carol Wilkinson @drcarolw.bsky.social · Dec 20
#3 Great! You are qualified and committed. There are lots of those applicants. What are you going to bring to this medical school that is going make a positive impact. How have you helped change things for the better in the work you have done or the people you work with.
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Carol Wilkinson @drcarolw.bsky.social · Dec 20
#2 Becoming a doctor is a long, tough (and amazing) path. Do you know what the path entails, and why is it the right path for you. Can you explain what parts of medicine and the training path (beyond helping people and liking science) excite you? How have your experiences lead you to this path?
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Carol Wilkinson @drcarolw.bsky.social · Dec 20
#1 whether you sink or swim is based on (a) academics - will you be able digest all the medschool material and pass the tests, and (b) your personal skills - can you build rapport with patients, communicate clearly, and work on a team.

Lots of ways to show this, even with a bad orgo grade.
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Carol Wilkinson @drcarolw.bsky.social · Dec 20
Gave some advice to prospective medstudents. I think it was sound…but can folks on admissions or teaching medstudents can give me a thumbs up or down?

TLDR: medschool evaluate (1) whether you will sink or swim, (2) are you committed to the profession, and (3) will you make a positive impact.
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Carol Wilkinson @drcarolw.bsky.social · Dec 19
Putting this years holiday lab gift to use - had to keep one for myself! #braincoaster #perlerbeads
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Carol Wilkinson @drcarolw.bsky.social · Dec 18
Holiday Lab Yankee Swap! Not pictured - me and my new brain notebook!
Lab members sitting around a table smiling, showing the gifts they received.
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Carol Wilkinson @drcarolw.bsky.social · Dec 11
As an ESI, I have not submitted to eLife since the switch bc it’s not clear how pubs in eLife are considered by promotion committees or grant reviewers. Not sure if this solves that concern, but also agree it is an experiment - albeit one that ESIs are nervous to participate in…
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Carol Wilkinson @drcarolw.bsky.social · Dec 4
Amazing and well deserved! Congratulations!
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Carol Wilkinson @drcarolw.bsky.social · Nov 13
Oops! Yes I am! Sorry about that. Thanks for organizing!
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Carol Wilkinson @drcarolw.bsky.social · Nov 13
Thanks for making! Can you add me? Thanks!!
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Carol Wilkinson @drcarolw.bsky.social · Oct 31
Happy Halloween from my zoo- lab!
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Carol Wilkinson @drcarolw.bsky.social · Jul 10
Our paper - Developmental trajectories of EEG aperiodic and periodic components in children 2-to-44 months of age - now published in Nature Communications. Interesting dynamic changes in alpha and beta peaks that we think are related to steps in early thalamocortical development.
rdcu.be/dNj0I
Developmental trajectories of EEG aperiodic and periodic components in children 2–44 months of age
Nature Communications - Using longitudinal EEG data from 592 infants and toddlers, the authors identify age-dependent nonlinear changes in periodic alpha and beta peaks suggestive of distinct...
rdcu.be
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