Dr. Dale Bredesen
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drdalebredesen.bsky.social
Dr. Dale Bredesen
@drdalebredesen.bsky.social
Dr. Dale Bredesen is the author of The Ageless Brain and The End of Alzheimer's, the Chief Science Officer of Apollo Health, and a pioneer in brain health research.
Alzheimer's disease blood biomarkers rose much more quickly in obese individuals, showing obesity is a modifiable risk, according to research from our colleague Cyrus Raji. https://sciencedaily.com/releases/2025/12/251210092019.htm
February 4, 2026 at 9:00 PM
The Randomized Control Trial isn’t just the most successful Alzheimer’s trial ever, it’s a building block for even more future success. Read more about what’s ahead in my new blog for Apollo Health.

https://www.apollohealthco.com/archimedes-alzheimer-and-trials-a-place-to-stand/
January 29, 2026 at 9:47 PM
Even after years of warnings, millions with dementia are still prescribed drugs linked to falls and confusion. Do not wait for the medical establishment to catch up to the science—take steps now to prevent and reverse cognitive decline. https://sciencedaily.com/releases/2026/01/260113220915.htm
January 25, 2026 at 8:10 PM
On January 23rd at 2pm PT, Dr. Craig Tanio, one of the key trial investigators, will describe enhancements to the ReCODE protocol.

To register for the webinar, click here: https://us02web.zoom.us/webinar/register/WN_-ROlIql_QtqcawMw_bIEhw#/registration
January 22, 2026 at 7:20 PM
Arginine can help reduce the risk of tooth decay, shifts the oral microbiome, and reduces acid formation in the mouth. Given the mouth-brain connection, could an arginine oral rinse be neuroprotective? https://scitechdaily.com/goodbye-cavities-this-natural-amino-acid-helps-teeth-fight-sugar/
January 21, 2026 at 8:15 PM
This is an important chart from our recent preprint of the Evanthea trial, which was based on ReCODE.

You don’t need to accept the standard of care or settle for a reduced rate of decline - it is possible to reverse the symptoms of Alzheimer’s: https://www.apollohealthco.com/evanthea-trial/
January 18, 2026 at 8:42 PM
The Evanthea randomized clinical trial has concluded, and the cognitive improvements exceed anything previously published. Join Dr. Bredesen on Friday, January 9th at 2 PM PT to discuss: https://us02web.zoom.us/webinar/register/WN_dMG3GyFlSLigtQoSanuUQA#/registration
January 7, 2026 at 6:28 PM
Your body’s natural cleaning crew, mononuclear phagocytes, do less cleaning as they age. By developing “young” phagocytes using stem cells, researchers improved memory and created healthier microglia in mice. https://www.sciencealert.com/young-immune-cells-partly-reverse-alzheimers-symptoms-in-mice
January 4, 2026 at 7:16 PM
Happy New Year to all, and I hope that everyone is enjoying time with loved ones. Meanwhile, we have very exciting results from our randomized controlled trial, and these have just been posted as a preprint: https://www.preprints.org/frontend/manuscript/8118568f183e2ba91ec2a1d3b3d08fb9/download_pub
December 31, 2025 at 9:20 PM
Breakthroughs in medical research are addressing 4 of the world's most serious health problems: Alzheimer's, cancer, pandemics, & antibiotic resistance. Learn about advances provided by 21st-Century medicine in my new blog. https://www.apollohealthco.com/solving-four-of-the-worlds-health-problems/
December 30, 2025 at 10:20 PM
Free radicals generated in non-neuronal brain cells promote dementia, according to researchers. Their study suggests that blocking this activity can protect the brain. https://news.weill.cornell.edu/news/2025/11/study-pinpoints-source-of-free-radicals-in-the-brain-that-may-fuel-dementia
December 28, 2025 at 4:25 PM
A longitudinal study found that those with moderate to severe obstructive sleep apnea were far more likely to have visible cerebral microbleeds on MRIs. Identifying yet another way that sleep apnea could contribute to cognitive decline. https://www.medpagetoday.com/pulmonology/sleepdisorders/118302
December 26, 2025 at 11:15 PM
Those brief bouts of attention wandering may actually be moments of brain maintenance! Attentional failures, particularly after sleep deprivation, could be the result of your brain working to remove waste. https://www.sciencealert.com/zoning-out-may-be-your-brains-rinse-cycle-study-finds
December 21, 2025 at 7:35 PM
In an observational study, teens who took the antibiotic doxycycline, which is a common prescription for acne, had a reduced risk of developing schizophrenia. https://www.sciencealert.com/common-acne-medication-linked-with-30-lower-schizophrenia-risk
December 13, 2025 at 7:10 PM
Tooth infections can lead to bacteria in the bloodstream, inflammation, and impaired blood sugar control. But root canals can lower blood sugar levels. https://www.theguardian.com/science/2025/nov/18/root-canal-treatment-could-significantly-lower-blood-sugar-levels-study-suggests
December 8, 2025 at 4:15 PM
Neuronic is finalizing a study on light therapy. We should wait for the final results, but it's good to see improvements in sleep, quality-of-life, hand-eye coordination, recognition, & auditory perception. https://www.neuronic.online/blog/can-light-therapy-help-with-memory-what-our-study-revealed
December 6, 2025 at 10:47 PM
An analysis of studies found that nitrous oxide can provide rapid improvements and also sustained benefits after repeat treatments for those with depression, especially for those who haven't responded to other treatments. https://sciencedaily.com/releases/2025/12/251202052213.htm
December 4, 2025 at 10:00 PM
Clearing beta-amyloid plaques does not repair key brain functions, according to new research on the drug lecanemab. The researchers are, unfortunately, just catching up to what we’ve all known. http://sciencealert.com/one-of-our-biggest-hopes-for-alzheimers-treatment-doesnt-seem-to-work
November 29, 2025 at 5:00 PM
A research team “rebalanced the activity” of a specific set of overactive neurons in the amygdala of mice and found that they reversed the symptoms of anxiety. https://www.sciencedaily.com/releases/2025/11/251104013004.htm
November 26, 2025 at 9:30 PM
Walnuts, which are high in omega-3 fatty acids, polyphenols, flavonoids, and antioxidants, supported focus and memory and improved cognitive function in a new study. For max benefit, consume raw to protect the omega-3 fatty acids. https://foodandwine.com/walnuts-breakfast-brain-health-study-11840393
November 22, 2025 at 7:37 PM
Frequent consumption of ultra-processed foods was associated with altered brain structure, and those differences could be part of a feedback loop promoting overeating, according to a study of 30,000 participants. https://sciencedaily.com/releases/2025/10/251020092824.htm
November 21, 2025 at 3:55 PM
A new device is helping those with advanced age-related macular degeneration see again, and likely provides cognitive protection by supporting brain stimulation. https://www.nbcnews.com/health/health-news/tiny-eye-implant-special-glasses-legally-blind-patients-can-read-rcna238488
November 12, 2025 at 9:15 PM
Live from Palm Springs at the California Assisted Living Association Conference! 🌴 Discussing how The Vineyards translates our research into real-life programs for their residents. Learn more about our partnership here: https://lifeatthevineyards.org/cognitive-care
The Vineyards Center for Cognitive Excellence™
The Vineyards dedicated Cognitive Care provides those with Alzheimer’s or other forms of dementia with a positive, stimulating environment.
lifeatthevineyards.org
November 11, 2025 at 9:03 PM
Join Dr. Dale Bredesen and Judy Benjamin this Tuesday, October 28th at 3:00pm PT / 6:00pm ET as we go LIVE to talk about the final stretch of her historic walk across America.

To sign up for the webinar, click here: https://us02web.zoom.us/webinar/register/WN_8GTSk8TTRnO8Obn9QN8LhQ
October 27, 2025 at 5:30 PM
Flavanols, found in green tea, berries, broccoli, and other foods, have long been found to reduce cardiovascular disease risk. Now, a study shows flavanol-rich supplements reduced age-related inflammation, likely promoting cognitive health as well. https://doi.org/10.1093/ageing/afaf269
October 23, 2025 at 6:20 PM