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dricechallal.bsky.social
Drice Challal
@dricechallal.bsky.social
41 followers 130 following 4 posts
Gene regulation, RNA, RBP Assistant Professor, Université Paris Cité, EGM - IBPC, CNRS
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dricechallal.bsky.social
Drice Challal @dricechallal.bsky.social · Apr 5
Thrilled to see our story now out at @naturecomms.bsky.social
A shared adventure with Estelle Leroy and Mathieu Rougemaille @i2bcparissaclay.bsky.social, and with the precious help of the @palancadelab.bsky.social
Such a tiny RNA with such a wide range of functions
www.nature.com/articles/s41...
4 8 13
Reposted by Drice Challal
clemdf.bsky.social
Clementine Delan-Forino @clemdf.bsky.social · Apr 15
🚨 New preprint! 🚨
We just dropped our latest work on RNA-binding proteins and sporulation in B. subtilis! Turns out, the RBP landscape gets a major remix during sporulation 👀. Check it out here 👉 www.biorxiv.org/content/10.1...
#RBP #RNA #sporulation #Bacillus #microbiology @lcbofficiel.bsky.social
Remodeling of RNA-Binding Proteome and RNA-mediated regulation as a new layer of control of sporulation
Sporulation allows certain bacteria to survive extreme conditions for extended periods posing challenges to public health and food safety. Transcriptional level of regulation relying on σ factors has ...
www.biorxiv.org
1 7 13
Reposted by Drice Challal
jagodnikscience.bsky.social
Jonathan Jagodnik @jagodnikscience.bsky.social · Apr 6
I am thrilled to share this new preprint from our lab!
We find (>800!) 30S binding sites in hundreds of 5'UTRs, but also new dynamic steps of translation initiation.
www.biorxiv.org/content/10.1...
Congrats to all co-authors at the RNA control of gene expression lab, IBPC CNRS
(Thread, 1/6)
30S-seq redefines the bacterial Ribosome Binding Site
The translation initiation step is rate limiting for the efficiency of gene expression in all organisms. However, the mechanism of ribosome recruitment to mRNA start sites strikingly differs between e...
www.biorxiv.org
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dricechallal.bsky.social
Drice Challal @dricechallal.bsky.social · Apr 5
2/2
The result of a collective effort by all the members of the Rougemaille lab and others, including @jessicaandreani.bsky.social
A work supported by @agencerecherche.bsky.social, @fondationarc.bsky.social, @cnrs.fr and @univparissaclay.bsky.social
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dricechallal.bsky.social
Drice Challal @dricechallal.bsky.social · Apr 5
Thrilled to see our story now out at @naturecomms.bsky.social
A shared adventure with Estelle Leroy and Mathieu Rougemaille @i2bcparissaclay.bsky.social, and with the precious help of the @palancadelab.bsky.social
Such a tiny RNA with such a wide range of functions
www.nature.com/articles/s41...
4 8 13
Reposted by Drice Challal
mlejars.bsky.social
Maxence Lejars @mlejars.bsky.social · Mar 21
Happy to share our genetic toolkit designed to make your gene editing (life) easier, faster and very efficient!

Also suitable to build saturated chromosomal variant libraries using oligo-recombineering with extra short homology arms!

www.biorxiv.org/content/10.1...
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dricechallal.bsky.social
Drice Challal @dricechallal.bsky.social · Mar 22
Merci beaucoup for your precious contribution to this work !

@I2BCParisSaclay

x.com/ASadylab/statu…
dricechallal.bsky.social
Drice Challal @dricechallal.bsky.social · Mar 22
My main Ph.D project on the role of General Regulatory Factors in protecting promoters from ectopic and divergent transcription initiation is now available. So enthusiastic to finally see the result of this great adventure with @DomenicoLibri @LabLibri
@MolecularCell

x.com/MolecularCell/…