Earl K. Miller
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earlkmiller.bsky.social
Earl K. Miller
@earlkmiller.bsky.social
Picower Professor of Neuroscience @ MIT
Cognitive neuroscience, executive brain functions, consciousness, and bass guitar. You know, the good stuff.
ekmillerlab.mit.edu
Co-founder, Neuroblox
https://www.neuroblox.ai/
Reposted by Earl K. Miller
How do brain areas control each other? 🧠🎛️

✨In our NeurIPS 2025 Spotlight paper, we introduce a data-driven framework to answer this question using deep learning, nonlinear control, and differential geometry.🧵⬇️
November 26, 2025 at 7:32 PM
Neuroblox provides the first multi-scale and mechanistic neural circuit simulation platform for modeling brain function.
www.neuroblox.ai
A Neuroblox model even made a new discovery!
www.biorxiv.org/content/10.1... (in press, Nat. Comm) #neuroscience
Neuroblox | In Silico Neural Circuit Modeling for Neurotherapeutic Design
Neuroblox provides the first multiscale and mechanistic neural circuit simulation platform built to elicit cognition, mood, and behavior for designing neurotherapeutics.
www.neuroblox.ai
November 26, 2025 at 2:47 PM
Distinct roles of prefrontal subregion feedback to the primary visual cortex across behavioral states
www.cell.com/neuron/abstr...
#neuroscience
Distinct roles of prefrontal subregion feedback to the primary visual cortex across behavioral states
Ährlund-Richter et al. show that in mice, discrete subregions of the prefrontal cortex send distinct feedback signals to the primary visual cortex. These pathways differentially modulate visual proces...
www.cell.com
November 25, 2025 at 4:07 PM
Soon in Nature Comm. A biomimetic model NOT trained on data eerily matched neurophys data from animals performing the same task. It predicted a new neural property that was then found in the data! Plus, this model generated oscillatory rhythms that were functional.
www.biorxiv.org/content/10.1...
www.biorxiv.org
November 24, 2025 at 6:50 PM
Dysfunctional oscillatory bursting patterns linked to working memory in adolescents with attention deficit hyperactivity disorder
link.springer.com/article/10.3...
#neuroscience
Dysfunctional oscillatory bursting patterns linked to working memory in adolescents with attention deficit hyperactivity disorder - Cognitive, Affective, & Behavioral Neuroscience
Background Identifying neural markers of clinical symptom fluctuations is prerequisite to developing more precise brain-targeted treatments in psychiatry. We have recently shown that working memory (W...
link.springer.com
November 22, 2025 at 7:44 PM
Beta-band frequency shifts signal decisions in human prefrontal cortex
www.cell.com/iscience/ful...
#neuroscience
Beta-band frequency shifts signal decisions in human prefrontal cortex
Natural sciences; Biological sciences; Neuroscience; Clinical neuroscience
www.cell.com
November 22, 2025 at 7:42 PM
A neuroecological perspective on the prefrontal cortex
doi.org/10.1016/j.ne...
#neuroscience
Redirecting
doi.org
November 22, 2025 at 7:38 PM
New paper! Brains stretch representations along task-relevant dimensions. Spike timing is important.
www.nature.com/articles/s41...
#neuroscience
Adaptive stretching of representations across brain regions and deep learning model layers - Nature Communications
How the brain adapts its representations to prioritize task-relevant information remains unclear. Here, the authors show that both monkey brains and deep learning models stretch neural representations...
www.nature.com
November 21, 2025 at 2:44 PM
Theta-nested gamma oscillations balance prediction and vigilance in spatial navigation
doi.org/10.1073/pnas...
#neuroscience
Theta-nested gamma oscillations balance prediction and vigilance in spatial navigation | PNAS
Recent experimental findings challenge the traditional belief that vigilance is solely attributed to the sensorimotor system, suggesting instead th...
doi.org
November 20, 2025 at 7:03 PM
Today, Nov 20 at noon ET.
The MIT Consciousness Club seminar
Consciousness Emerges From Neural Dynamics
Earl K. Miller
Zoom link here:
sites.google.com/view/mit-con...
MIT Consciousness Club
The MIT Consciousness Club aims to foster interdisciplinary research on consciousness at MIT and in the broader Boston area by organizing a monthly event featuring an expert talk on consciousness foll...
sites.google.com
November 20, 2025 at 12:59 PM
Reposted by Earl K. Miller
Half your brain cells are astrocytes, oscillating and modulating activity without spiking, while cortical neurons spike sparsely. So nearly 100% of cells are oscillating almost all the time, but only a minority of cells emit rare spikes. Maybe spikes are the tail and oscillations are the dog.
November 19, 2025 at 3:57 PM
Tomorrow 12pm (ET) at the MIT Consciousness Club. Consciousness Emerges From Neural Dynamics - Earl K. Miller (hey, that's me!). Join us via Zoom.
sites.google.com/view/mit-con...
#neuroscience
MIT Consciousness Club
The MIT Consciousness Club aims to foster interdisciplinary research on consciousness at MIT and in the broader Boston area by organizing a monthly event featuring an expert talk on consciousness foll...
sites.google.com
November 19, 2025 at 12:56 PM
The science of consciousness
Through the MIT Consciousness Club, professors Matthias Michel and Earl Miller are exploring how neurological activity gives rise to human experience.
news.mit.edu/2025/science...
#neuroscience
The science of consciousness
The MIT Consciousness Club, led by professors Matthias Michel and Earl Miller, explores how neurological activity gives rise to human experience.
news.mit.edu
November 19, 2025 at 2:30 AM
Giant Shoulders podcast: Meet the MIT Neuroscientist Proving Brainwaves are the Secret to Consciousness.
youtu.be/7OFb-NG3jIw
#neuroscience
Meet the MIT Neuroscientist Proving Brain Waves Are the Secret Engine Behind Consciousness
YouTube video by Giant's Shoulder
youtu.be
November 18, 2025 at 6:18 PM
Reposted by Earl K. Miller
Next up, a special lecture by Rony Paz, introduced by @stevewcchang.bsky.social. I’m really excited for this one!

Emotional Learning and the Primate Amygdala: From Adaptive Behaviors to Psychopathologies.

www.abstractsonline.com/pp8/#!/21171...
November 16, 2025 at 8:08 PM
Reposted by Earl K. Miller
Heard at #SfN25 from @earlkmiller.bsky.social: Cognition and consciousness emerge from the dynamic organization of the cortex produced by traveling brain waves performing analog computations. picower.mit.edu/news/brain-w... #neuroscience #consciousness #cognition @mitbcs.bsky.social
Brain waves’ analog organization of cortex enables cognition and consciousness, MIT professor proposes at SfN
On neuroscience’s big stage Nov. 15, MIT Professor Earl K. Miller proposed that thought and consciousness emerge from the fast and flexible organization of the cortex produced by the analog computatio...
picower.mit.edu
November 16, 2025 at 4:24 AM
Mastering wine tasting. Who said neuroscience meetings aren't fun?
##SFN2025
November 15, 2025 at 6:23 PM
Miller Lab at #SFN2025. Come by and say hi ya. #Neuroscience
November 14, 2025 at 11:53 AM
Coming to the Society for Neuroscience meeting? Come to my lecture and say hi. I'm going to be talking about some crazy stuff. #neuroscience #SFN2025
November 14, 2025 at 11:15 AM
Beta frequency shifts in decision making: Spectral fingerprints or communication channels?
arxiv.org/abs/2511.03503
#neuroscience
Beta frequency shifts in decision making: Spectral fingerprints or communication channels?
Recent evidence suggests that beta-band activity plays a key role in decision-making. Here we review our recent work in humans and non-human primates showing that beta-band frequency shifts in frontal...
arxiv.org
November 10, 2025 at 5:12 PM
Dynamic Interplay between Prefrontal Theta and Beta Bursts Facilitates Flexible Learning
doi.org/10.5607/en25...
#neuroscience
Dynamic Interplay between Prefrontal Theta and Beta Bursts Facilitates Flexible Learning
Hahyeon Park, Haseong Kim, Eunyoung Yeo and Alan Jung Park. Exp Neurobiol -0001;0:. https://doi.org/10.5607/en25034
doi.org
November 10, 2025 at 4:56 PM
Hidden Spirals Reveal Neurocomputational Mechanisms of Traveling Waves in Human Memory
doi.org/10.1101/2025...
#neuroscience
Hidden Spirals Reveal Neurocomputational Mechanisms of Traveling Waves in Human Memory
Traveling waves are neural oscillations that progressively propagate across the cortex in specific directions and spatial patterns, however, their underlying mechanisms remain elusive. To probe their ...
doi.org
November 8, 2025 at 2:45 PM