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Dong-Jiunn Jeffery Truong

@earthnut89.bsky.social

28 followers 60 following 1 posts

Passionate molecular lego player :). Developing molecular tools for live monitoring of fundamental biological processes that were not trackable before. Optimizing and developing genome engineering, gene therapy, and delivery tools.

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Dong-Jiunn Jeffery Truong @earthnut89.bsky.social · Apr 9

www.cell.com/cell/fulltex...
ENVLPE, our system for VLP-based delivery of gene editors, is now published in @cellcellpress.bsky.social. We showed efficient delivery of base- and prime-editors in primary T cells & in vivo retinal models. All core constructs are available from @addgene.bsky.social.

Engineered nucleocytosolic vehicles for loading of programmable editors

Engineered nucleocytosolic vehicles for loading of programmable editors (ENVLPE) with enhanced CRISPR ribonucleoprotein (RNP) loading and stabilization enable the efficient delivery of gene-editing ef...

www.cell.com

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Reposted by Dong-Jiunn Jeffery Truong

Helmholtz Munich @helmholtzmunich.bsky.social · Apr 9

Engineering Smart Delivery for Gene Editors 🧬
👉 t1p.de/vmdc9

Researchers from #HelmholtzMunich & @tum.de created ENVLPE – a modular, virus-like system that delivers CRISPR/Cas9 tools into cells with unprecedented efficiency.

#GeneEditing #CRISPR #CancerTherapy

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