Epigenome Technologies
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epigenometech.bsky.social
Epigenome Technologies
@epigenometech.bsky.social
550 followers 1.8K following 740 posts
Epigenome Technologies, pioneering in epigenetic and single-cell analysis, offers advanced assay kits and optimization services.
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epigenometech.bsky.social
Download our poster to learn how we applied Droplet Paired-Tag to Alzheimer's disease post-mortem brain tissue to reveal specific cellular changes and potential therapeutic targets

#Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics #Alzheimers

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January 23, 2026 at 4:31 PM
epigenometech.bsky.social
Epigenetics Update - Single-cell atlas of the transcriptome and chromatin accessibility in the human retina go.nature.com/45lLrOY

#Epigenetics #SingleCell #Chromatin #Retina
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Empower your research with high-res epigenetic insights at epigenometech.com
January 23, 2026 at 12:40 PM
epigenometech.bsky.social
Epigenetics Update - Epigenetic dysregulation of metabolic programs mediates liposarcoma cell plasticity bit.ly/49MvSAZ

Eliezer M. Van Allen (Dana-Farber Cancer Institute) in Science TM

#Epigenetics #Liposarcoma #Cancer
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Perfect for cancer, immunology, and aging research; epigenometech.com
January 23, 2026 at 8:41 AM
epigenometech.bsky.social
Learn how we used Droplet Paired-Tag to assess RNA expression and histone modifications in individual brain cells and PBMCs to identify novel cell-type-specific CREs and heritability factors linked to AD

#Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics #Alzheimers

bit.ly/4kgWMF3
January 22, 2026 at 5:01 PM
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Epigenetics Update - Dissecting gene regulatory networks governing human cortical cell fate go.nature.com/4b9X4w7

Alex A. Pollen (University of California San Francisco) reporting in Nature
#Epigenetics #GRNs #Chromatin
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Gain deeper insights into gene regulation; epigenometech.com
January 22, 2026 at 12:32 PM
epigenometech.bsky.social
Epigenetics Update - Molecular underpinnings of induced degenerative heterogeneity in the retinal pigment epithelium bit.ly/3Zop084

James T. Handa (Johns Hopkins) reported in PNAS

#Epigenetics #RPE #RetinalDegeneration
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Discover the breakthrough at epigenometech.com
Molecular underpinnings of induced degenerative heterogeneity in the retinal pigment epithelium | PNAS
Cigarette smoking induces epigenetic changes that can cause degenerative heterogeneity with aging and disease. In disease such as age-related macul...
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January 22, 2026 at 8:13 AM
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New Epigenome Technologies Blog post! bit.ly/3NpAzJD

"DNA Damage Repair and Longevity in Naked Mole-Rats"

Based on a Science article from Ying Jiang and Zhiyong Mao (Tongji University)

#Epigenetics #Blog #Aging #Longevity #NakedMoleRats
January 21, 2026 at 5:08 PM
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Epigenetics Review - Mechanical regulation of metabolism, epigenetics, and their interplay
go.nature.com/4jKxTCt

Sungmin Nam (University of Michigan) reported in NPJ Biomed Innov

#Epigenetics #Review #Metabolism
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High-resolution insights without cell sorting; epigenometech.com
January 21, 2026 at 2:36 PM
epigenometech.bsky.social
Epigenetics Update - Single-cell atlas of the developing Down syndrome brain cortex go.nature.com/4qBaOon

Michael Lattke and Vincenzo De Paola reporting in Nat Med

#Epigenetics #DownSyndrome #SingleCell #Multiomics
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Empower your research with high-res epigenetic insights at epigenometech.com
January 21, 2026 at 8:46 AM
epigenometech.bsky.social
Join an upcoming webinar from Epigenome Technologies and @epicypher.bsky.social to learn how Paired-Damage-seq can reveal cell-type-specific DNA damage patterns and provide new insights into disease mechanisms!

January 29 | 10:00 AM PST

Register here: lnkd.in/eM_dv3yR

#Epigenetics #DNADamage
January 20, 2026 at 8:46 PM
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Download our poster to learn how we used single-cell CUT&Tag and Droplet Paired-Tag to profile PBMCs, generating over 70,000 single-cell profiles and identifying vast numbers of cis-regulatory elements

#Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics

bit.ly/4kgWMF3
January 20, 2026 at 5:03 PM
epigenometech.bsky.social
Epigenetics Update - Metformin inhibits nuclear egress of chromatin fragments in senescence and aging go.nature.com/4qsb09y

Zhixun Dou (Harvard University) reported in Nat Aging

#Epigenetics #Aging #Chromatin
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Perfect for cancer, immunology, and aging research; epigenometech.com
January 20, 2026 at 12:18 PM
epigenometech.bsky.social
Epigenetics Review - Epigenetic consequences of DNA damage bit.ly/45QCPjh

Tanya T. Paull (University of Texas) and Patricia L. Opresko (University of Pittsburgh) reported in Mol Cell

#Epigenetics #Review #DNADamage
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Gain deeper insights into gene regulation; epigenometech.com
Epigenetic consequences of DNA damage
DNA damage is not only a threat to genome integrity but also a driver of epigenetic regulation. This review highlights how oxidative lesions, R-loops, telomere damage, double-strand breaks, and PARP s...
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January 20, 2026 at 8:26 AM
epigenometech.bsky.social
Epigenome Technologies will be at the Arkansas Biotech Convergence on Weds Jan 22nd

Join us for a great day filled with excellent talks from experts in the field

If you are interested in single-cell epigenetics, drop by our booth!

#PairedTag #SingleCell #Meeting #EpigenomeTech #Epigenetics
January 19, 2026 at 8:03 PM
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Epigenome Technologies offers an end-to-end single-cell Paired-Tag service, the first multiomic assay that simultaneously captures RNA expression and epigenetic marks from preparation to data analysis

#Epigenetics #SingleCell #PairedTag #Multiomics

bit.ly/3HWFoaw
January 19, 2026 at 4:30 PM
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Epigenetics Update - Multiomic integration reveals tumoral heterogeneity of lipid dependence within lethal group 3 medulloblastoma bit.ly/49AgeZu

#Epigenetics #Multiomics #Medulloblastoma
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Discover the breakthrough at epigenometech.com
January 19, 2026 at 1:01 PM
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Epigenetics Update - Combined inhibition of FACT and BET disrupts transcription to suppress tumor growth in mouse models of diffuse midline glioma bit.ly/3NhLWmZ

#Epigenetics #Cancer #Glioma

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High-resolution insights without cell sorting; epigenometech.com
Combined inhibition of FACT and BET disrupts transcription to suppress tumor growth in mouse models of diffuse midline glioma
FACT and BET inhibition in diffuse midline glioma drives tumor suppression and immune modulation, highlighting a dual therapeutic strategy.
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January 19, 2026 at 9:12 AM
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New from Epigenome Technologies: Paired-Tag - the first single-cell multiomic assay that simultaneously captures RNA expression and epigenetic marks

#Epigenetics #SingleCell #PairedTag #Multiomics

Find out more at: bit.ly/4efqM1Y
January 16, 2026 at 4:33 PM
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Epigenetics Update - Astronauts as a Human Aging Model: Epigenetic Age Responses to Space Exposure bit.ly/4jIXzPS

David Furman (Buck Institute for Research on Aging) in Aging Cell

#Epigenetics #SpaceTravel #EpigeneticAging #Aging
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Empower your research at epigenometech.com
January 16, 2026 at 12:18 PM
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Epigenetics Update - A distinct monocyte transcriptional state links systemic immune dysregulation to pulmonary impairment in long COVID go.nature.com/49TzEd7

#Epigenetics #Immunology #COVID
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Perfect for cancer, immunology, and aging research; epigenometech.com
January 16, 2026 at 8:27 AM
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Epigenome Technologies offers an end-to-end Single-Cell CUT&Tag service

Our expert scientists run the entire workflow on your samples - from preparation to data analysis

#Epigenetics #SingleCell #CUTandTag

Find out more at: bit.ly/4kPxe2i
January 15, 2026 at 5:05 PM
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Epigenetics Update - A robust computational framework for methylation age and disease-risk prediction based on pairwise learning go.nature.com/49wDPu4

#Epigenetics #DNAm #Aging #PairwiseLearning
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Gain deeper insights into gene regulation; epigenometech.com
January 15, 2026 at 12:18 PM
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Epigenetics Update - Interplay between cohesin and RNA polymerase II in regulating chromatin interactions and gene transcription go.nature.com/49iRJkK

Albert W. Cheng and Yijun Ruan (Jackson Laboratory) reporting in NSMB

#Epigenetics #Chromatin
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Discover the breakthrough at epigenometech.com
January 15, 2026 at 8:19 AM
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New Epigenome Technologies Blog post! bit.ly/45aibKP

" Single-Cell Multi-Regional Atlas of DNA Methylation and 3D Chromatin Conformation in the AD-Affected Brain"

Based on a preprint from Bradley T. Hyman and Joseph R. Ecker

#Epigenetics #Chromatin #DNAme #ChromatinConformation #AD
January 14, 2026 at 4:47 PM
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Epigenetics News - How Diet and Cold Rewire Brown Fat at the Epigenetic Level bit.ly/458510U

#Epigenetics #Chromatin #News #Obesity #Metabolism
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High-resolution insights without cell sorting; epigenometech.com
How Diet and Cold Rewire Brown Fat at the Epigenetic Level
A team of researchers from the Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG), an institute of Helmholtz Munich at the Leipzig University, in collaboration with the University Hospital of Leipzig Medical Center and the CRC1052 “Obesity Mechanisms”, has revealed how diet and cold exposure change the activity of brown fat at the genetic level. Brown fat helps the body generate heat, and the study shows that obesity changes how brown fat responds to cold.
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January 14, 2026 at 1:01 PM