Epigenome Technologies
epigenometech.bsky.social
Epigenome Technologies
@epigenometech.bsky.social
Epigenome Technologies, pioneering in epigenetic and single-cell analysis, offers advanced assay kits and optimization services.
Epigenome Technologies offers an end-to-end single-cell Paired-Tag service, the first multiomic assay that simultaneously captures RNA and epigenetic marks (we run the workflow on your samples) from preparation to data analysis

#Epigenetics #SingleCell #PairedTag #Multiomics

bit.ly/3HWFoaw
November 25, 2025 at 4:39 PM
Epigenetics Update - A chromatin-linked CPL2–PHD2/3 module sustains multiple DNA methylation pathways and Polycomb silencing bit.ly/3LYXKd5

Jian-Kang Zhu reporting in PNAS

#Epigenetics #Chromatin #DNAm #Polycomb #Plants
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Perfect for cancer, immunology, and aging research; epigenometech.com
November 25, 2025 at 1:09 PM
Epigenetics Update - Engineered chromatin readers track damaged chromatin dynamics in live cells and animals go.nature.com/4ikfHPs

Richard Cardoso da Silva and Tuncay Baubec reporting in Nat Commun

#Epigenetics #Chromatin
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Gain deeper insights into gene regulation; epigenometech.com
November 25, 2025 at 8:28 AM
New from Epigenome Technologies: Paired-Tag - the first single-cell multiomic assay that simultaneously captures RNA expression and epigenetic marks

#Epigenetics #SingleCell #PairedTag #Multiomics

Find out more at: bit.ly/4efqM1Y
November 24, 2025 at 4:15 PM
Epigenetics Update - Addressing the specific roles of histone modifications in transcriptional repression go.nature.com/4pqQXXQ

Kristian Helin (MSKCC/University of Copenhagen) reporting in Nat Commun

#Epigenetics #HisMods #Chromatin
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Discover the breakthrough at epigenometech.com
November 24, 2025 at 12:10 PM
Epigenetics News - Epigenetic changes regulate gene expression, but what regulates epigenetics? bit.ly/4oc4NMI

A paper from Guanghui Xu and Julie Law in Nat Cell Biol

#Epigenetics #News #Plants
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High-resolution insights without cell sorting; epigenometech.com
Epigenetic changes regulate gene expression, but what regulates epigenetics? - Salk Institute for Biological Studies
LA JOLLA—All the cells in an organism have the exact same genetic sequence. What differs across cell types is their epigenetics—meticulously placed chemical tags that influence which genes are express...
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November 24, 2025 at 8:19 AM
Learn more about single-cell epigenetic profiling by downloading our guide to single-cell CUT&Tag and single-cell Paired-Tag, which provides comparisons to other methods and bioinformatic insight!

bit.ly/4r7CGRD

#Epigenetics #Multiomics #CUTandTag #10XGgenomics #ChIPSeq #SingleCell #PairedTag
November 21, 2025 at 3:03 PM
Epigenetics Update – Transcription factors instruct DNA methylation patterns in plant reproductive tissues go.nature.com/4rbGrFR

Julie A. Law reporting in Nat Cell Biol

#Epigenetics #DNAm #Plants #Chromatin
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Perfect for cancer, immunology, and aging research; epigenometech.com
November 21, 2025 at 11:47 AM
Epigenetics Preprint - Brain Region-Specific Epigenomic Reorganization and Altered Cell States in Alzheimer’s Disease bit.ly/4rfHt3M

Bradley T. Hyman (Harvard) and Joseph R. Ecker (Salk)

#Epigenetics #Preprint #AlzheimersDisease
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Gain deeper insights into gene regulation; epigenometech.com
November 21, 2025 at 8:50 AM
Epigenome Technologies offers an end-to-end Single-Cell CUT&Tag service

Our expert scientists run the entire workflow on your samples - from preparation to data analysis

#Epigenetics #SingleCell #CUTandTag

Find out more at: bit.ly/4kPxe2i
November 20, 2025 at 4:26 PM
Epigenetics Update - Genetic elements promote retention of extrachromosomal DNA in cancer cells go.nature.com/4rqIyWz

Paul S. Mischel and Howard Y. Chang (Stanford University) reporting in Nature

#Epigenetics #ecDNA #DNAm
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Discover the breakthrough at epigenometech.com
November 20, 2025 at 1:04 PM
Epigenetics Update - Physical models reveal indirect reader protein interactions that facilitate epigenetic crosstalk bit.ly/47Nroui

Andrew J. Spakowitz (Stanford University) reporting in PNAS
#Epigenetics #Chromatin #Models

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High-resolution insights without cell sorting; epigenometech.com
Physical models reveal indirect reader protein interactions that facilitate epigenetic crosstalk | PNAS
The spatial organization of chromatin is governed by epigenetic factors, including epigenetic marks and the reader proteins that bind them. By dict...
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November 20, 2025 at 8:40 AM
New Epigenome Technologies Blog post! bit.ly/47LGMay

"Chromatin States in Pancreatic Ductal Adenocarcinoma Control Metastatic Spread"

Based on a Nature Cancer paper from Kaloyan M. Tsanov and Scott W. Lowe

#Epigenetics #Blog #EpigenomeTech #PDAC #Metastasis #Chromatin
November 19, 2025 at 5:02 PM
Epigenetics Update - High-throughput capture of actively transcribed region-interacting sequences reveals an intricate promoter-centered regulatory network bit.ly/448YNNG

#Epigenetics #Chromatin #ChromatinConformation
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Empower your research with high-res epigenetic insights at epigenometech.com
November 19, 2025 at 12:41 PM
Epigenetics Update - Disentangling the architectural and non-architectural functions of CTCF and cohesin in gene regulation go.nature.com/488ztZx

#Epigenetics #CTCF #Chromatin #Cohesin
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Perfect for cancer, immunology, and aging research; epigenometech.com
November 19, 2025 at 8:07 AM
New from Epigenome Technologies: the first fully validated Single-Cell CUT&Tag kit!

Fully compatible with 10x Chromium® (ATAC) or Fluent PiP-seq®

#Epigenetics #SingleCell #CUTandTag

Find out more at: bit.ly/4lquJDv
November 18, 2025 at 3:58 PM
Reposted by Epigenome Technologies
Out today, our take on 6-methyladenine #6mA evolution in Eukaryotes @natgenet.nature.com. We asked a simple question, is really DNA 6mA common across the eukaryotes? The answer is "yes" if you're a unicellular eukaryote 🦠, not so if you're multicellular 🐝🌱🍄. www.nature.com/articles/s41... 1/9
Adenine DNA methylation associated with transcriptionally permissive chromatin is widespread across eukaryotes - Nature Genetics
Long-read sequencing in 18 unicellular eukaryotes reveals that 6mA is widespread across eukaryotes and is enriched at transcriptionally permissive regions, which are also marked by H3K4me3.
www.nature.com
November 18, 2025 at 12:00 PM
Epigenetics Update - Adenine DNA methylation associated with transcriptionally permissive chromatin is widespread across eukaryotes go.nature.com/4r4V8KN

Alex de Mendoza (QMU, London) in Nat Genet

#Epigenetics #DNAm #Chromatin
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Gain deeper insights into gene regulation; epigenometech.com
November 18, 2025 at 11:51 AM
Epigenetics Update – Distinct transcriptomic and epigenomic responses of mature oligodendrocytes during disease progression in a mouse model of multiple sclerosis go.nature.com/4r1zwyQ

#Epigenetics #Multiomics #SingleCell #MultipleSclerosis
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Discover the breakthrough at epigenometech.com
November 18, 2025 at 8:09 AM
Our expansion of single-cell epigenetics assays continues!
The Epigenome Technologies scCUT&Tag assay is now compatible with the BD Rhapsody platform

Learn more here: lnkd.in/g3YqPrWY

#Epigenetics #BDRhapsody #CUTandTag #Chromatin #Multiomics #SingleCell #CUTandRUN #ChIPseq #ATACseq
November 17, 2025 at 5:10 PM
Epigenetics Update – A primordial germ cell-like-cell platform enables CRISPRi screen for epigenetic fertility modifiers bit.ly/48iiPI3

John C Schimenti (Cornell University) reporting in EMBO J

#Epigenetics #PGCs #Fertility #CRISPR
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High-res insights without cell sorting; epigenometech.com
November 17, 2025 at 12:05 PM
Calling all neurobiologists with an interest in epigenetics, single cell epigenomics,....and FREE BEER!!!

Join us for craft beers, bites, and brain-related science discussions in the East Village - a short 10-minute walk from the San Diego Convention Center!

RSVP: lnkd.in/gjNWFmrh
November 17, 2025 at 8:03 AM
We have recently expanded our single-cell epigenetics assays!

Our Emulsion scCUT&Tag assay is now compatible with the Illumina PIPseq platform

Learn more at lnkd.in/g3YqPrWY

#SingleCell #EpigenomeTech #PairedTag #Multiomics #Epigenetics #scCUTandTag #PIPseq
November 14, 2025 at 4:54 PM
Epigenetics Update - Single-nucleus multi-omics identifies shared and distinct pathways in Pick's and Alzheimer's disease bit.ly/3XxbQ7P

Vivek Swarup reporting in Sci Adv

#Epigenetics #SingleCell #Multiomics #PicksDisease #AlzheimersDisease
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Discover the breakthrough at epigenometech.com
November 14, 2025 at 12:42 PM
Epigenetics Update - snoRNA Snord3 promotes rheumatoid arthritis by epigenetic regulation of ESM1 in fibroblast-like synoviocytes in mice bit.ly/47CYvRt

#snoRNA #Epigenetics #RheumatoidArthritis #Snord3
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High-resolution insights without cell sorting; epigenometech.com
snoRNA Snord3 promotes rheumatoid arthritis by epigenetic regulation of ESM1 in fibroblast-like synoviocytes in mice
snoRNA Snord3-mediated epigenetic activation of ESM1 is a potential therapeutic target in rheumatoid arthritis.
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November 14, 2025 at 9:12 AM