Esther van Kleef
@esthervk.bsky.social
690 followers 370 following 25 posts
Infectious disease epidemiologists working on AMR, modelling and ID surveillance @WHO and UoOxford. Alone we move fast, together we move mountains
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esthervk.bsky.social
This has been a huge undertaking and a great leap forward in reporting global AMR surveillance data. For the first time, country, and regional-level data are supported my Bayesian modelling that allow for better comparison of resistance rates between countries/ regions and trends over time @who.int
esthervk.bsky.social
Coming Monday 13 October, WHO will launch the latest Global antibiotic resistance surveillance report. Don't miss it, register here! www.who.int/news-room/ev...
Reposted by Esther van Kleef
gmknght.bsky.social
Very excited for this event on the 9th July!

It's part of our #AMR short course but open to everyone as it's online. Do join in and here what the amazing Prof Dame Sally Davies has to stay on the current status of global action on #AMR! @lshtmamrcentre.bsky.social
lshtmamrcentre.bsky.social
🎙️ Join Prof Dame Sally Davies, for an insightful seminar on global action against AMR.

In this seminar, she will share updates on the UN High-Level AMR agenda, the evidence panel & what’s next for global policy.

📅 9 July 2025
🕰️ 13:00 BST
📍 Online
🔗 bit.ly/4kVSVgP
Reposted by Esther van Kleef
quentinlclrc.bsky.social
We're recruiting a postdoc in our lab @mesurs-cnam.bsky.social (Paris) to work on epidemic modelling over healthcare networks, as part of the EU project ARCANE ! 💻🦠
Start date between 09/25-01/26, 2y contract

Interested in AMR, healthcare-related research & mathematical modelling? Find out more! ⬇️
IDDjobs — Postdoctoral position in epidemic modelling over healthcare networks — Conservatoire national des Arts et Métiers
Find infectious disease dynamics modelling jobs, studentships, and fellowships.
iddjobs.org
esthervk.bsky.social
Great ID modelling opportunity to aim for real impact on mitigating and monitoring AMR in sub-Saharan Africa. You'll work closely with us @ox.ac.uk, and Oxford’s Modernising Medical Microbiology group, as well as collaborators at CRUN (Burkina Faso) and KWRTP-KEMRI (Kenya). tinyurl.com/mry25kxe
Epidemiologist
Epidemiologist for modelling AMR transmission in LMICMore than 500 staff members at the Institute of Tropical Medicine (ITM) contribute e...
tinyurl.com
esthervk.bsky.social
Certainly! And sharing the knowledge here in England whenever I can now stroopwafels are almost as much an export product as Gouda cheese…
esthervk.bsky.social
The first preview was also presented at ESCMID global see tinyurl.com/4sh5v3hf. Combined these reports provide valuable new insights to enhance country-level use of GLASS data to help inform local, national, and regional AMR strategies World Health Organization #UNGA.
esthervk.bsky.social
The GLASS report on antimicrobial resistance (AMR) will be published separately later this year. The 2025 GLASS AMR report will expand on previous editions by presenting regional- CTA-level AMR estimates and trends across 93 pathogen-antibiotic combinations from CTAs enrolled by the end of 2024.
esthervk.bsky.social
The latest Global Antimicrobial Resistance and Use Surveillance System (GLASS) report on antimicrobial use is now out, reporting on 2022 national AMU surveillance data globally tinyurl.com/3muyp2pu @who.int .
esthervk.bsky.social
Emphasising the relevance of such information is something I feel we should target, among others by working on direct ways (eg good dashboards) of feeding back national and local AMR/isolate data. Until then, we are limited to reporting AMR prevalence.
esthervk.bsky.social
On another note: WHO GLASS has moved to individual isolate reporting since 2023. This is great and will provide a first possibility to move beyond reporting prevalences only. But countries to date struggle even to report much needed denominators for incidence.
esthervk.bsky.social
In addition, national surveillance guidance is underway, aiming to inform national action, not global estimates as a stand alone. Discussion are ongoing. For an early version of the survey guidance, see here www.who.int/publications.... Of note: both ACORN I and II and these surveys are intensive.
GLASS method for estimating attributable mortality of antimicrobial resistant bloodstream infections
Global Antimicrobial Resistance Surveillance System (GLASS)
www.who.int
esthervk.bsky.social
Good news is that WHO and ACORN collaborators have been working on this in tandem, I.e currently piloted WHO surveys on estimating burden, incl. all indicators presented by ACORN are developed in close consultation with/borrowing from similar protocols for places where MML access is challenging
esthervk.bsky.social
Our findings can inform the design of pandemic intelligence systems now emerging across Europe and globally, and support efforts like the Lancet Commission on Strengthening the Use of Epidemiological Modelling—to guide future policy, methods, and communication. 4/5
esthervk.bsky.social
We argue that future preparedness should focus on collaborative platforms and cross-border modelling networks - supporting standardisation, open data/code, and strong links between academia, public health, and data providers. 3/5
esthervk.bsky.social
- Need for better data stratification, standardisation, and code sharing practices

- Collaboration between scientists and decision-makers became more formal over time, evolving from informal network. How can we build on these established structures? 2/5
esthervk.bsky.social
Here are some of the key challenges identified:

- Need for sustainable data collection systems beyond case counts and include risk monitoring and ready-to-deploy protocols

- Importance of non-public data providers (e.g. private tech companies) and the need to rethink long-term access frameworks
esthervk.bsky.social
How should we redesign data and modelling ecosystems for future crises?

NEW PREPRINT: Drawing on survey insights from modelling teams across Europe, we explored how modelling practices, data-sharing, science-policy links, and evidence use evolved during the pandemic: tinyurl.com/4mptshh7 1/5
Reposted by Esther van Kleef
esthervk.bsky.social
More to come at @escmid.bsky.social in the eposter flash session "A global perspective on antimicrobial resistance surveillance" 13 April 16.15-17.15. Hope to see you all there!
esthervk.bsky.social
In the session "Translating AMR Clinical Needs from Local to Global" she covered:
* Regional disparities BSI aetiologies
* Resistance patterns by region and country, using Bayesian hierarchical models
* Challenges in GLASS data interpretation & WHO’s strategy to boost global surveillance
esthervk.bsky.social
At the 9th AMR Conference in Basel today, Olga Tosas Auguet from @who.int shared key updates on global AMR trends from the Global Antimicrobial Resistance and Use Surveillance System (GLASS).
esthervk.bsky.social
Rather than resistricting risk monitoring to reactive outbreak response, we highlight effective applications that enhance early detection and prevention of outbreaks. This aligns with #CollaborativeSurveillance @who.int and its advocacy for integrated/ cross-sectoral approaches to ID surveillance.
ingelbeen.bsky.social
NEW PAPER: When and how to embed risk data in infectious disease surveillance?

Problem: Traditional infectious disease surveillance consisting of facility-based reporting of cases, often delays outbreak response due to disease progression, healthcare seeking, diagnostic and reporting lags. 1/5