In addition to the RibonanzaNet server hosted by @rdaslab.bsky.social, RNA structure fans can try the new pseudoknotted prediction model in Eterna's RNet Study collection. The 108 puzzles are a mix of experimentally-validated structures and synthetic fabrications.
eternagame.org/collections/...

Not exactly citizen science, but such a fun way to connect people with Nature.

Long-standing myths about “silly science” have contributed to the reckless slashing of government-supported research.

Here's a fun G-quad puzzle: eternagame.org/puzzles/1347...

Celebrate World RNA Day on August 1 with Eterna
In the latest Education Corner, learn about Eterna, an online game which models the base pairing and secondary structure of RNA sequences
cdn.rcsb.org/rcsb-pd...

Coming up this weekend, Eternacon will feature presentations about fellow #citsci platform @zooniverse.bsky.social and how participants of both Zooniverse and Eterna have created #machinelearning tools for projects. @noirlabastro.bsky.social

Register for free at eternagame.org/eternacon/2025

Hear directly from Eterna lead developer and Frameshifter director @luxaritas.com at Eternacon this weekend: eternagame.org/eternacon/2025

This is a step that our team has discussed for some time,
and we initially shared our plan to start a new organization with our community a few months ago. We're excited to move forward with this next step in Eterna's governance. Same core staff and a renewed focus on sustaining and growing Eterna.

Meet @frameshifter.org, the new nonprofit program established to steward Eterna's future and advance public engagement in scientific research through games, collective and hybrid intelligence, and human centered design.

Eterna players successfully designed antisense oligonucleotides (ASOs) to bind with specific regions of the intron and restore F8 exon 16 splicing. A big thank you to @ucscscience.bsky.social for collaborating with us on this cutting-edge research! #citizenscience @rdaslab.bsky.social

Registration for Eterna's annual online conference July 26-27 is open! Come hear from both researchers and players about new approaches to structure-based RNA design and understanding RNA structure. #citsci

Full program and free registration at eternagame.org/eternacon/2025

Summer Newsletter Published
Highlights training events, the Ligand Expo shutdown; accessing IHM data at RCSB PDB, and more. In the Education Corner, learn about Interactive RNA Education with the Eterna Game.
cdn.rcsb.org/rcsb-pd...

Zooniverse taking the lead in using #machinelearning as a tool for participatory science projects.

Looking forward to attending my first Conference for Advancing the Participatory Sciences this week and delivering a presentation during the Scientific Contributions session on how Eterna players created a large dataset of RNA sequences with pseudoknots for machine learning. 🧪

#CAPS2025

Eterna players support the RNA research being performed by academic labs at US universities and strongly believe federal funding of these research programs should be fully restored to maintain America's leadership in both science and biomedical entrepreneurship.

National DNA Day celebrates the completion of the human genome project in 2003 and the discovery of the double helix in 1953. The continuing work of dedicated scientists to learn more about the functioning of genes and RNA in the human body is leading to important advances in medicine.

If you weren't able to attend the workshop, be sure to stop by booth 502 to see our RNA folding game in action.
#ASBMB25

Tomorrow morning in room 470! #ASBMB25

Machine learning should be able to pick up on the reactivity patterns of these structural motifs, such as tetraloop receptors.

#RNAsky

"The chemical alphabet of RNA is also
harder to interpret: the four chemical bases
that make up RNA are less distinct than the
20 amino acids found in proteins. That means
that each RNA base contains less information
than an amino acid."

True, but RNA has distinct structural motifs.

Great review of new RNA structure prediction methods!

Videos of the presentations are available on the Eterna website at eternagame.org/eternacon/2024.

Eternacon 2025 will be July 26-27.

🧬Come get involved with #citizenscience!🧪

Our 2024 online conference featured two talks on how innovative Eterna players helped RNA structure researchers improve the preparation of RNA sequences for chemical mapping, particularly formatting the padding and barcodes to reduce primer misfolds and smooth read counts. (Link below⬇️)

Hello World

The Eterna RNA structure modeling and puzzle platform has landed in the much happier place. We look forward to continuing conversations with the biochemistry, molecular biology, bioinformatics, machine learning, and participatory science communities.