Francesca Cesari
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francesari.bsky.social
Francesca Cesari
@francesari.bsky.social
Chief Biological, Clinical and Social Sciences Editor of Nature

Any views expressed here are my own
Speech sounds like vowels and consonants in native and foreign languages elicit similar neural responses in the superior temporal, but only during native listening does this area encode word boundaries, frequency, and language-specific information.
🧪 www.nature.com/articles/s41...
Shared and language-specific phonological processing in the human temporal lobe - Nature
The human superior temporal gyrus processes acoustic–phonetic properties of speech regardless of whether the language is familiar to the listener, but only encodes word boundaries and language-sp...
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November 21, 2025 at 3:44 PM
Marburg virus is a highly virulent/transmissible filovirus with no vaccine/treatments and recent outbreaks in Africa. Scientists have isolated/characterized a highly potent neutralizing monoclonal antibody effective against Marburg and related viruses Dehong and Ravn.🧪
www.nature.com/articles/s41...
Potent neutralization of Marburg virus by a vaccine-elicited antibody - Nature
Nature - Potent neutralization of Marburg virus by a vaccine-elicited antibody
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November 19, 2025 at 8:39 AM
A Nature paper details a new AI model called EchoPrime, which can read and interpret echocardiograms 🧪👇
www.nature.com/articles/s41...
Comprehensive echocardiogram evaluation with view primed vision language AI - Nature
Nature - Comprehensive echocardiogram evaluation with view primed vision language AI
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November 19, 2025 at 8:34 AM
A study looks at the mortality impacts of unmanaged rainfall and future sea level rise, with disproportionate risk for children, women, and residents of slums in a developing megacity🧪
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November 19, 2025 at 8:32 AM
Computer vision, on which many AI applications rely on, is based on non-consensual datasets, compromising fairness and accuracy in AI. Now, an ethically curated, diverse human-image data set, sets a new standard for responsible data curation and trustworthy AI. 🧪 www.nature.com/articles/s41...
Fair human-centric image dataset for ethical AI benchmarking - Nature
The Fair Human-Centric Image Benchmark (FHIBE, pronounced ‘Feebee’)—an image dataset that implements best practices for consent, privacy, compensation, safety, diversity and utility—can be used respon...
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November 12, 2025 at 2:58 PM
A paper in Nature reports high-resolution structures of aSyn fibrils 1B and their in vivo seeding product 1BP. They appear remarkably similar, suggesting a high-fidelity conformational replication process to perpetuate MSA-like pathology 🧪👇
www.nature.com/articles/s41...
Synthetic α-synuclein fibrils replicate in mice causing MSA-like pathology - Nature
Synthetic fibril strain 1B is a pathogen that is capable of self-replication and inducing glial cytoplasmic inclusions in vivo in mice, and the structural features of 1B may underlie the pathology of ...
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November 12, 2025 at 2:44 PM
Snake bites kill/debilitate 1000s of people annually in Sub-Saharan African. A new nanobody cocktail is shown to be highly effective against 17 of the most dangerous African snake species. Unlike other anti-venoms it also protects against venom-induced dermal necrosis🧪
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Nanobody-based recombinant antivenom for cobra, mamba and rinkhals bites - Nature
A recombinant antivenom composed of eight nanobodies provides broad protection against venom-induced lethality and dermonecrosis in mice challenged with venoms from cobras, mambas and rinkha...
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October 30, 2025 at 7:26 AM
A new study in published in Nature presents a comprehensive resource of immunological changes occurring during normal aging 🧪
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Multi-omic profiling reveals age-related immune dynamics in healthy adults - Nature
This multi-omic longitudinal analysis of the healthy human peripheral immune system constructs the Human Immune Health Atlas and assembles data on immune cell composition and state changes w...
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October 30, 2025 at 7:20 AM
Where do invertebrates without calcium-rich bones or shells store their calcium? In the fruit-fly, at least, it’s the malpighian tubules, where calcium is mobilised by a neuropeptide hormone called Capability. 🧪
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Neuroendocrine control of calcium mobilization in the fruit fly - Nature
The peptide hormone Capa is responsible for regulating extracellular fluid Ca2+ levels in the fruit fly Drosophila melanogaster.
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October 30, 2025 at 7:19 AM
An article in Nature reports that ecosystem energy flow, through food consumption by wild birds and mammals, has decreased by over one third in sub-Saharan Africa since around 1700 🧪
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Energy flows reveal declining ecosystem functions by animals across Africa - Nature
An ecosystem energetics approach, quantifying trophic energy flows across species, offers a unified framework for linking animal biodiversity loss to changes in ecosystem function and Earth system pro...
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October 30, 2025 at 7:17 AM
A short-necked sauropodomorph from a new Triassic locality in Argentina shows sign of the neck extension that characterised its larger, later cousins.🧪👇
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A long-necked early dinosaur from a newly discovered Upper Triassic basin in the Andes - Nature
Discovery of a nearly complete skeleton of Huayracursor jaguensis, a Carnian dinosaur from the Northern Precordillera Basin in northwestern Argentina provides evidence of increased body size and early...
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October 23, 2025 at 1:18 PM
A vaccine central in A(H5) influenza virus antigenic space confers subtype-wide immunity 🧪👇
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A vaccine central in A(H5) influenza antigenic space confers broad immunity - Nature
A high-resolution antigenic map of influenza A(H5) haemagglutinin (HA) enables the design of immunogenic and antigenically central vaccine HA antigens that elicit antibody responses broadly covering t...
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October 23, 2025 at 1:16 PM
A paper in Nature presents MetaGraph, which indexes petabase-scale biological sequences for accurate and efficient searches across vast sequence space 🧪👇
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Efficient and accurate search in petabase-scale sequence repositories - Nature
MetaGraph enables scalable indexing of large sets of DNA, RNA or protein sequences using annotated de Bruijn graphs.
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October 8, 2025 at 4:54 PM
🧪 Women are represented as younger than men across occupations/social roles in data from Google,Wikipedia,IMDB, Flickr,YouTube and LLMs.The bias is strongest for occupations with high status/earnings.ChatGPT perpetuates this bias when generating and evaluating resumes. www.nature.com/articles/s41...
Age and gender distortion in online media and large language models - Nature
Stereotypes of age-related gender bias are socially distorted, as evidenced by the age gap in the representations of women and men across various media and algorithms, despite no systematic age differences in the workforce.
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October 8, 2025 at 4:53 PM
An article in Nature tracks trends in freshwater fish biodiversity in streams and rivers across the US over the last three decades and finds that fish biodiversity diverged across cold and warm streams, with a disproportionately large impact on cold streams.🧪
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Diverging fish biodiversity trends in cold and warm rivers and streams - Nature
In the past three decades, fish abundance, richness and uniqueness have diverged across cold and warm streams, and the effects on native fish communities of stream warming and increases in introduced fishes have magnified each other.
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September 25, 2025 at 5:22 PM
A study in Nature uncovers the mechanism behind a new metabolic class of drug for treatment of neuroblastoma 🧪👇
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Reprogramming neuroblastoma by diet-enhanced polyamine depletion - Nature
Enhanced polyamine depletion in neuroblastoma models decreases translation of mRNA codons with adenosine in the third position, reprogramming the tumour proteome away from cell cycle progression and towards differentiation.
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September 25, 2025 at 5:20 PM
In a Perspective article in Nature the Biodiversity Cell Atlas describes its plans and goals for mapping the tree of life with single-cell genomics technologies🧪👇
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The Biodiversity Cell Atlas: mapping the tree of life at cellular resolution - Nature
The Biodiversity Cell Atlas aims to create comprehensive single-cell molecular atlases across the eukaryotic tree of life, which will be phylogenetically informed, rely on high-quality genomes and use shared standards to facilitate comparisons across species.
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September 25, 2025 at 5:14 PM
A new study projects global burned areas and wildfire emissions using a machine learning–based approach, and estimates their impact on related mortality 🧪👇
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Global warming amplifies wildfire health burden and reshapes inequality - Nature
Nature - Global warming amplifies wildfire health burden and reshapes inequality
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September 19, 2025 at 11:10 AM
Repeated head trauma causes neuron loss and inflammation in young athletes 🧪👇
www.nature.com/articles/d41...
and the paper 👉 www.nature.com/articles/s41...
Years of hits to the head prime the brain for decline
Repetitive head impacts trigger neuronal loss and disrupt blood vessels and immune cells long before the accumulation of neurotoxic tau protein.
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September 19, 2025 at 11:06 AM
A study in Nature presents Delphi-2M, a medical AI tool for predicting future health-related events using data from medical records. 🧪👇
www.nature.com/articles/s41...
Learning the natural history of human disease with generative transformers - Nature
Delphi-2M forecasts a person’s future health, covering more than 1,000 diseases, provides insights into co-morbidity dynamics and generates synthetic data for the training of AI models that have never...
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September 19, 2025 at 11:02 AM
Do people cheat more when they delegate tasks to AI? A Nature paper shows that they do, and that LLMs are far more likely than humans to carry out unethical instructions (though it was possible to minimize this by including task-specific prohibitive guardrails).🧪👇
www.nature.com/articles/s41...
Delegation to artificial intelligence can increase dishonest behaviour - Nature
People cheat more when they delegate tasks to artificial intelligence, and large language models are more likely than humans to comply with unethical instructions—a risk that can be minimized by ...
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September 19, 2025 at 11:00 AM
A new study in Nature reports the development of programmable antisense oligomers (ASOs) to silence genes of both DNA and RNA phages, and is applied to understand the functions and phenotypes associated with key genes in jumbo phage ΦKZ
🧪👇
www.nature.com/articles/s41...
Programmable antisense oligomers for phage functional genomics - Nature
Establishing antisense oligomers as versatile, non-genetic tools to silence phage mRNAs opens applications in basic research and biotechnology, as shown by identifying essential factors for propagatio...
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September 11, 2025 at 10:51 AM
A study in Nature presents a new classification of human skeletal muscle subtypes in cancer cachexia, based on transcriptomics, including a comparison between human and rodent datasets. 🧪👇
www.nature.com/articles/s41...
Molecular subtypes of human skeletal muscle in cancer cachexia - Nature
Unbiased clustering analysis of the skeletal muscle RNAome in patients with cancer identifies two molecular subtypes, one of which distinguishes individuals with cachexia and indicates ...
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September 11, 2025 at 10:49 AM
The ant Messor ibericus lays eggs that develop into males of two different species. Females of one of the species clone males of the other. This may be the first known case of a male-only clonal lineage that reproduces solely through other species’ ova.🧪
www.nature.com/articles/s41...
One mother for two species via obligate cross-species cloning in ants - Nature
In a case of obligate cross-species cloning, female ants of Messor ibericus need to clone males of Messor structor to obtain sperm for producing the worker caste, resulting in males from the same moth...
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September 3, 2025 at 3:29 PM
Using epidemiological methods, a new study finds that the spread of the Great Fear during the French Revolution was not a result of emotional distress but rather the apparition of multiple independent locations. 🧪👇
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Epidemiology models explain rumour spreading during France’s Great Fear of 1789 - Nature
Epidemiological methods are used to show that the Great Fear of 1789, a series of peasant insurrections in rural revolutionary France, was driven by deliberate political action rather than spontaneous...
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September 3, 2025 at 2:36 PM