Geula Hanin
@geula.bsky.social
Group Leader @pdncambridge.bsky.social 🔬👩🏻🔬🧬🤱
Exploring #Lactation, #ImprintedGenes, #MammaryGlandDevelopment, #Metabolism and #DOHaD
Exploring #Lactation, #ImprintedGenes, #MammaryGlandDevelopment, #Metabolism and #DOHaD
Pinned
Geula Hanin
@geula.bsky.social
· Jul 7
🚨 Big news! I am thrilled to share that I’ll be establishing my independent research group at @pdncambridge.bsky.social University of Cambridge, supported by the MRC Career Development Award.
Reposted by Geula Hanin
A Comment article in Nature Reviews Bioengineering discusses how understanding pregnancy stage-specific drug pharmacokinetics and placental drug transport can guide the design of nanomedicine to optimize treatments during pregnancy. 🔒
Designing nanomedicine to overcome therapeutic challenges in pregnancy - Nature Reviews Bioengineering
Illness during pregnancy presents a therapeutic dilemma: treatment must protect the mother without compromising fetal health. Yet, most drugs remain insufficiently studied in pregnancy. Understanding pregnancy stage-specific drug pharmacokinetics and placental drug transport can guide the design of nanomedicine to optimize treatments during pregnancy.
go.nature.com
December 6, 2025 at 8:51 PM
A Comment article in Nature Reviews Bioengineering discusses how understanding pregnancy stage-specific drug pharmacokinetics and placental drug transport can guide the design of nanomedicine to optimize treatments during pregnancy. 🔒
Reposted by Geula Hanin
New content online: Oestrogen changes at menopause: insights into obesity-associated breast risk and outcomes
Oestrogen changes at menopause: insights into obesity-associated breast risk and outcomes
Nature Reviews Endocrinology, Published online: 02 December 2025; doi:10.1038/s41574-025-01208-7Oestrogen levels change after menopause and with weight gain above the normal BMI category, both of which can affect breast cancer risk and outcomes. This Review explores the current understanding of these associations.
www.nature.com
December 2, 2025 at 6:08 PM
New content online: Oestrogen changes at menopause: insights into obesity-associated breast risk and outcomes
Reposted by Geula Hanin
Big shoutout to Boshra Alsulaiti for driving this review! @geneticscam.bsky.social
November 14, 2025 at 12:52 PM
Big shoutout to Boshra Alsulaiti for driving this review! @geneticscam.bsky.social
🔥🤱Excited to share our new review “From Mammary Glands to Nutrients: Genetic Insights into Milk Composition”
We integrate GWAS, cross-species biology and biochemistry to reveal how maternal genetics shapes breastmilk and its essential role in mammalian life. tinyurl.com/bdevetkx
We integrate GWAS, cross-species biology and biochemistry to reveal how maternal genetics shapes breastmilk and its essential role in mammalian life. tinyurl.com/bdevetkx
From mammary glands to nutrients: genetic insights into milk composition†
This review integrates comparative perspectives on mammary gland development and lactation, highlighting genetic and epigenetic determinants that influence
tinyurl.com
November 14, 2025 at 12:52 PM
🔥🤱Excited to share our new review “From Mammary Glands to Nutrients: Genetic Insights into Milk Composition”
We integrate GWAS, cross-species biology and biochemistry to reveal how maternal genetics shapes breastmilk and its essential role in mammalian life. tinyurl.com/bdevetkx
We integrate GWAS, cross-species biology and biochemistry to reveal how maternal genetics shapes breastmilk and its essential role in mammalian life. tinyurl.com/bdevetkx
If this sounds like you - send me a DM/email with your CV + transcript + a few lines on your interests. I’d be happy to discuss ideas and support a competitive application.
www.findaphd.com/phds/program...
www.findaphd.com/phds/program...
FindAPhD : PhD Opportunities in the Department of Physiology, Development and Neuroscience at University of Cambridge
Apply for a PhD: PhD Opportunities in the Department of Physiology, Development and Neuroscience at University of Cambridge
www.findaphd.com
November 6, 2025 at 3:04 PM
If this sounds like you - send me a DM/email with your CV + transcript + a few lines on your interests. I’d be happy to discuss ideas and support a competitive application.
www.findaphd.com/phds/program...
www.findaphd.com/phds/program...
If you’re excited by lactation biology / mammary gland development / milk composition and want to do mechanistic work in vivo, get in touch.
You’ll need:
• strong academic track record (min good 2:1 or equivalent)
• essential: hands-on molecular biology experience
You’ll need:
• strong academic track record (min good 2:1 or equivalent)
• essential: hands-on molecular biology experience
November 6, 2025 at 3:04 PM
If you’re excited by lactation biology / mammary gland development / milk composition and want to do mechanistic work in vivo, get in touch.
You’ll need:
• strong academic track record (min good 2:1 or equivalent)
• essential: hands-on molecular biology experience
You’ll need:
• strong academic track record (min good 2:1 or equivalent)
• essential: hands-on molecular biology experience
Looking for a fully funded PhD in Cambridge? 🤱👩🔬🔬
I’m interested in hearing from strong candidates who want to apply with me to the competitive PhD funding scheme in the Department of Physiology, Development and Neuroscience @ Cambridge.
I’m interested in hearing from strong candidates who want to apply with me to the competitive PhD funding scheme in the Department of Physiology, Development and Neuroscience @ Cambridge.
November 6, 2025 at 3:04 PM
Looking for a fully funded PhD in Cambridge? 🤱👩🔬🔬
I’m interested in hearing from strong candidates who want to apply with me to the competitive PhD funding scheme in the Department of Physiology, Development and Neuroscience @ Cambridge.
I’m interested in hearing from strong candidates who want to apply with me to the competitive PhD funding scheme in the Department of Physiology, Development and Neuroscience @ Cambridge.
Reposted by Geula Hanin
Conventional wisdom says motherhood should wait for tenure as before you land a permanent post, #academia is just not that family friendly🙁
@carersinstemm.bsky.social are calling for change and to celebrate their new report, a Saturday🧵on parenting & academia! 1/9 👩🔬🧪🔭⚛️
ℹ️: carersinstemm.co.uk
@carersinstemm.bsky.social are calling for change and to celebrate their new report, a Saturday🧵on parenting & academia! 1/9 👩🔬🧪🔭⚛️
ℹ️: carersinstemm.co.uk
October 4, 2025 at 7:24 AM
Conventional wisdom says motherhood should wait for tenure as before you land a permanent post, #academia is just not that family friendly🙁
@carersinstemm.bsky.social are calling for change and to celebrate their new report, a Saturday🧵on parenting & academia! 1/9 👩🔬🧪🔭⚛️
ℹ️: carersinstemm.co.uk
@carersinstemm.bsky.social are calling for change and to celebrate their new report, a Saturday🧵on parenting & academia! 1/9 👩🔬🧪🔭⚛️
ℹ️: carersinstemm.co.uk
Reposted by Geula Hanin
Looking to pursue cutting-edge research in early development, maternal-fetal interaction, or placental biology? See 👇
- Funded PhD www.trophoblast.cam.ac.uk/phd-students...
- Next Generation Fellowship www.trophoblast.cam.ac.uk/next-generat...
- MPhil www.mphil.bio.cam.ac.uk/mphil-pathwa...
- Funded PhD www.trophoblast.cam.ac.uk/phd-students...
- Next Generation Fellowship www.trophoblast.cam.ac.uk/next-generat...
- MPhil www.mphil.bio.cam.ac.uk/mphil-pathwa...
October 2, 2025 at 8:15 AM
Looking to pursue cutting-edge research in early development, maternal-fetal interaction, or placental biology? See 👇
- Funded PhD www.trophoblast.cam.ac.uk/phd-students...
- Next Generation Fellowship www.trophoblast.cam.ac.uk/next-generat...
- MPhil www.mphil.bio.cam.ac.uk/mphil-pathwa...
- Funded PhD www.trophoblast.cam.ac.uk/phd-students...
- Next Generation Fellowship www.trophoblast.cam.ac.uk/next-generat...
- MPhil www.mphil.bio.cam.ac.uk/mphil-pathwa...
Reposted by Geula Hanin
A Genetic Atlas of the Mammary Gland 🧬🤱🐭
New research from @geula.bsky.social & team shows shifts in gene activity across pregnancy → lactation → weaning.
This new 'atlas' provides new avenues for studying lactation disorders and breast cancer.
academic.oup.com/nar/article/...
New research from @geula.bsky.social & team shows shifts in gene activity across pregnancy → lactation → weaning.
This new 'atlas' provides new avenues for studying lactation disorders and breast cancer.
academic.oup.com/nar/article/...
September 23, 2025 at 4:36 AM
A Genetic Atlas of the Mammary Gland 🧬🤱🐭
New research from @geula.bsky.social & team shows shifts in gene activity across pregnancy → lactation → weaning.
This new 'atlas' provides new avenues for studying lactation disorders and breast cancer.
academic.oup.com/nar/article/...
New research from @geula.bsky.social & team shows shifts in gene activity across pregnancy → lactation → weaning.
This new 'atlas' provides new avenues for studying lactation disorders and breast cancer.
academic.oup.com/nar/article/...
Reposted by Geula Hanin
🔥🚨 Our new paper is finally out in @narjournal.bsky.social!
academic.oup.com/nar/article/53/17/gkaf804/8248607
We built the first comprehensive atlas of dynamic allelic expression in the mouse mammary gland across adulthood, tracking genes across virgin, #pregnancy, #lactation & #involution.
🧵
academic.oup.com/nar/article/53/17/gkaf804/8248607
We built the first comprehensive atlas of dynamic allelic expression in the mouse mammary gland across adulthood, tracking genes across virgin, #pregnancy, #lactation & #involution.
🧵
Dynamic allelic expression in mouse mammary glands across the adult developmental cycle
Abstract. The mammary gland, which primarily develops postnatally, undergoes significant changes during pregnancy and lactation to facilitate milk producti
academic.oup.com
September 10, 2025 at 9:14 AM
🔥🚨 Our new paper is finally out in @narjournal.bsky.social!
academic.oup.com/nar/article/53/17/gkaf804/8248607
We built the first comprehensive atlas of dynamic allelic expression in the mouse mammary gland across adulthood, tracking genes across virgin, #pregnancy, #lactation & #involution.
🧵
academic.oup.com/nar/article/53/17/gkaf804/8248607
We built the first comprehensive atlas of dynamic allelic expression in the mouse mammary gland across adulthood, tracking genes across virgin, #pregnancy, #lactation & #involution.
🧵
Reposted by Geula Hanin
Breastfeeding boosts babies' lifelong health – but 1 in 20 women struggle.
@geula.bsky.social @geneticscam.bsky.social found that 'milk squeezing' cells, rather than 'milk-producing' cells, may be to blame.
Find out how this could lead to new ways to supporting mothers 👉 bit.ly/4mTUixN
@geula.bsky.social @geneticscam.bsky.social found that 'milk squeezing' cells, rather than 'milk-producing' cells, may be to blame.
Find out how this could lead to new ways to supporting mothers 👉 bit.ly/4mTUixN
Study of breast cell changes in motherhood provides clues to breastfeeding difficulties
A University of Cambridge study of adult mammary gland development has revealed new genes involved in breastfeeding, and provided insights into how genetic
bit.ly
September 10, 2025 at 11:05 AM
Breastfeeding boosts babies' lifelong health – but 1 in 20 women struggle.
@geula.bsky.social @geneticscam.bsky.social found that 'milk squeezing' cells, rather than 'milk-producing' cells, may be to blame.
Find out how this could lead to new ways to supporting mothers 👉 bit.ly/4mTUixN
@geula.bsky.social @geneticscam.bsky.social found that 'milk squeezing' cells, rather than 'milk-producing' cells, may be to blame.
Find out how this could lead to new ways to supporting mothers 👉 bit.ly/4mTUixN
Our atlas is open & ready to explore in this link: geulahanin-mammarygland.shinyapps.io/mammary_data...
Excited to see what the community will do with it!
Excited to see what the community will do with it!
Mammary ASE Explorer
geulahanin-mammarygland.shinyapps.io
September 10, 2025 at 9:14 AM
Our atlas is open & ready to explore in this link: geulahanin-mammarygland.shinyapps.io/mammary_data...
Excited to see what the community will do with it!
Excited to see what the community will do with it!
Big shoutout to my amazing co-authors 👏 thank you for your ideas and teamwork. A real privilege to work together on this! A special thank you to my mentor Anne Ferguson-Smith, for her guidance and support! @geneticscam.bsky.social
September 10, 2025 at 9:14 AM
Big shoutout to my amazing co-authors 👏 thank you for your ideas and teamwork. A real privilege to work together on this! A special thank you to my mentor Anne Ferguson-Smith, for her guidance and support! @geneticscam.bsky.social
Why does it matter?
💡 We identify new targets for lactation failure
💡 Early risk markers for postpartum breast cancer
💡 Insight into how maternal vs paternal genes control lactation
💡 We provide a comprehensive public atlas for the community
💡 We identify new targets for lactation failure
💡 Early risk markers for postpartum breast cancer
💡 Insight into how maternal vs paternal genes control lactation
💡 We provide a comprehensive public atlas for the community
September 10, 2025 at 9:14 AM
Why does it matter?
💡 We identify new targets for lactation failure
💡 Early risk markers for postpartum breast cancer
💡 Insight into how maternal vs paternal genes control lactation
💡 We provide a comprehensive public atlas for the community
💡 We identify new targets for lactation failure
💡 Early risk markers for postpartum breast cancer
💡 Insight into how maternal vs paternal genes control lactation
💡 We provide a comprehensive public atlas for the community
We also find that postpartum breast cancer–associated genes are activated after weaning in a cell type often overlooked in the mammary gland, revealing early molecular signals specific to postpartum breast cancer.
September 10, 2025 at 9:14 AM
We also find that postpartum breast cancer–associated genes are activated after weaning in a cell type often overlooked in the mammary gland, revealing early molecular signals specific to postpartum breast cancer.
Interestingly, we found that genes linked to lactation problems aren’t confined to milk-producing cells. They’re also active in other mammary cells like mammary adipocytes and stromal cells, broadening our view of what drives successful lactation.
September 10, 2025 at 9:14 AM
Interestingly, we found that genes linked to lactation problems aren’t confined to milk-producing cells. They’re also active in other mammary cells like mammary adipocytes and stromal cells, broadening our view of what drives successful lactation.
Our atlas revealed 25 imprinted genes in the mammary gland, uncovered novel regulators of lactation and showed that genes linked to breastfeeding failure & postpartum breast cancer are active in unexpected cell types.
September 10, 2025 at 9:14 AM
Our atlas revealed 25 imprinted genes in the mammary gland, uncovered novel regulators of lactation and showed that genes linked to breastfeeding failure & postpartum breast cancer are active in unexpected cell types.
So address this, we built the most detailed mammary dataset yet: 480 transcriptomes, 6 cell types, 10 developmental stages and reciprocal hybrid crosses with 4 biological replicates: A time-lapse map of gene activity across motherhood.
September 10, 2025 at 9:14 AM
So address this, we built the most detailed mammary dataset yet: 480 transcriptomes, 6 cell types, 10 developmental stages and reciprocal hybrid crosses with 4 biological replicates: A time-lapse map of gene activity across motherhood.
Why?
Breastfeeding is vital for both mother & infant, but the genetic & epigenetic regulation of lactation remains poorly understood. Imprinted genes, which exert parent-of-origin-specific effects, drive prenatal growth. We asked if they also shape early nutrition by regulating lactation.
Breastfeeding is vital for both mother & infant, but the genetic & epigenetic regulation of lactation remains poorly understood. Imprinted genes, which exert parent-of-origin-specific effects, drive prenatal growth. We asked if they also shape early nutrition by regulating lactation.
September 10, 2025 at 9:14 AM
Why?
Breastfeeding is vital for both mother & infant, but the genetic & epigenetic regulation of lactation remains poorly understood. Imprinted genes, which exert parent-of-origin-specific effects, drive prenatal growth. We asked if they also shape early nutrition by regulating lactation.
Breastfeeding is vital for both mother & infant, but the genetic & epigenetic regulation of lactation remains poorly understood. Imprinted genes, which exert parent-of-origin-specific effects, drive prenatal growth. We asked if they also shape early nutrition by regulating lactation.
🔥🚨 Our new paper is finally out in @narjournal.bsky.social!
academic.oup.com/nar/article/53/17/gkaf804/8248607
We built the first comprehensive atlas of dynamic allelic expression in the mouse mammary gland across adulthood, tracking genes across virgin, #pregnancy, #lactation & #involution.
🧵
academic.oup.com/nar/article/53/17/gkaf804/8248607
We built the first comprehensive atlas of dynamic allelic expression in the mouse mammary gland across adulthood, tracking genes across virgin, #pregnancy, #lactation & #involution.
🧵
Dynamic allelic expression in mouse mammary glands across the adult developmental cycle
Abstract. The mammary gland, which primarily develops postnatally, undergoes significant changes during pregnancy and lactation to facilitate milk producti
academic.oup.com
September 10, 2025 at 9:14 AM
🔥🚨 Our new paper is finally out in @narjournal.bsky.social!
academic.oup.com/nar/article/53/17/gkaf804/8248607
We built the first comprehensive atlas of dynamic allelic expression in the mouse mammary gland across adulthood, tracking genes across virgin, #pregnancy, #lactation & #involution.
🧵
academic.oup.com/nar/article/53/17/gkaf804/8248607
We built the first comprehensive atlas of dynamic allelic expression in the mouse mammary gland across adulthood, tracking genes across virgin, #pregnancy, #lactation & #involution.
🧵
Registration is still open to attend the Cambridge Lactation Network summer symposium: 11 September, 1.30pm-5.00pm
Join us for presentations about breastfeeding and lactation through the lens of public health, clinical practice, biological mechanisms, and patient/participant experience.
Join us for presentations about breastfeeding and lactation through the lens of public health, clinical practice, biological mechanisms, and patient/participant experience.
📝 Registration is free but required to attend.
🔗 Reserve your place here: www.eventbrite.de/e/cambridge-...
@aj-twigger.bsky.social @koulman.bsky.social @cam-repro.bsky.social
🔗 Reserve your place here: www.eventbrite.de/e/cambridge-...
@aj-twigger.bsky.social @koulman.bsky.social @cam-repro.bsky.social
Cambridge Lactation Network Summer Symposium
Join us for an enjoyable and informative meeting to learn more about the lactation research done in and around Cambridge!
www.eventbrite.de
August 28, 2025 at 11:03 AM
Registration is still open to attend the Cambridge Lactation Network summer symposium: 11 September, 1.30pm-5.00pm
Join us for presentations about breastfeeding and lactation through the lens of public health, clinical practice, biological mechanisms, and patient/participant experience.
Join us for presentations about breastfeeding and lactation through the lens of public health, clinical practice, biological mechanisms, and patient/participant experience.
📝 Registration is free but required to attend.
🔗 Reserve your place here: www.eventbrite.de/e/cambridge-...
@aj-twigger.bsky.social @koulman.bsky.social @cam-repro.bsky.social
🔗 Reserve your place here: www.eventbrite.de/e/cambridge-...
@aj-twigger.bsky.social @koulman.bsky.social @cam-repro.bsky.social
Cambridge Lactation Network Summer Symposium
Join us for an enjoyable and informative meeting to learn more about the lactation research done in and around Cambridge!
www.eventbrite.de
August 14, 2025 at 3:40 PM
📝 Registration is free but required to attend.
🔗 Reserve your place here: www.eventbrite.de/e/cambridge-...
@aj-twigger.bsky.social @koulman.bsky.social @cam-repro.bsky.social
🔗 Reserve your place here: www.eventbrite.de/e/cambridge-...
@aj-twigger.bsky.social @koulman.bsky.social @cam-repro.bsky.social
We’ll explore topics ranging from public health and global milk banking to molecular biology and lived experiences of breastfeeding.
Alongside thought-provoking talks, there will be plenty of opportunities for discussion, networking and sharing ideas over drinks and light bites.
Alongside thought-provoking talks, there will be plenty of opportunities for discussion, networking and sharing ideas over drinks and light bites.
August 14, 2025 at 3:40 PM
We’ll explore topics ranging from public health and global milk banking to molecular biology and lived experiences of breastfeeding.
Alongside thought-provoking talks, there will be plenty of opportunities for discussion, networking and sharing ideas over drinks and light bites.
Alongside thought-provoking talks, there will be plenty of opportunities for discussion, networking and sharing ideas over drinks and light bites.