New postdoc position in our lab (2 y+): evolutionary genomics of integrons and MGEs with focus on vibrio-phage interactions. Great environment @pasteur.fr for science, career building. Super collaborators @celineloot.bsky.social @amazeld.bsky.social @fredoleroux.bsky.social 3 weeks to apply!

All the credit for this discovery goes to postdoc @giuliapasquesi.bsky.social , who first noticed the isoform in her 2020 Lockdown Sideproject (tm). Her perseverance, creativity, and talent made this study possible and it was an honor to be a part of it. Watch out for her--she's on the job market! 😉

A story of transposons, innate immunity, and how human (and primates) possess an endogenous system to tune interferon response through the relative expression level of a signaling receptor and its alternatively spliced decoy.

It wouldn't be my profile otherwise 😍

First work out of my Postdoc (and the pandemic) in 2022. We looked at the contribution of TEs to bat immune responses. Surprisingly, no strong evidence in support of genome-wide epigenetic activation of TEs in response to IFN (contrary to other mammals)!
link.springer.com/article/10.1...

Following up on Nat. Commun. 2018, we analyzed the relationship between TE transcription and expression levels of genes involved in TE silencing in somatic and germline tissues across vertebrates.
doi.org/10.1093/gbe/...

One of my favorite works. And it had been an honor to be a part of it
genome.cshlp.org/content/29/4...

In the awe of next week big reveal, a little bit of my past.
My very first First-author paper (Nat Commun 2018), as a grad student in Todd Castoe lab. We showed unique characteristics of the conflict between genome size and TE activity in squamates compared to other amniotes.
doi.org/10.1038/s414...