Greg Larssen
@greglarssen.bsky.social
Houston born & bred living in the land of my mother, France. Overlooking the sea & the Pyrénées, unearthing small caps potential is a passion & pastime.🇺🇸🇨🇵🇺🇦
Hi Scott,
Waiting for the madness to calm down, and seeing what the destruction of our NIH, FDA, and Medicaid will yield as many of my stocks, BNGO included, have a dependency on these.
In times of madness, posting about stocks is futile, but still watching, daily, and day trading. We'll see.
Waiting for the madness to calm down, and seeing what the destruction of our NIH, FDA, and Medicaid will yield as many of my stocks, BNGO included, have a dependency on these.
In times of madness, posting about stocks is futile, but still watching, daily, and day trading. We'll see.
May 16, 2025 at 7:11 AM
Hi Scott,
Waiting for the madness to calm down, and seeing what the destruction of our NIH, FDA, and Medicaid will yield as many of my stocks, BNGO included, have a dependency on these.
In times of madness, posting about stocks is futile, but still watching, daily, and day trading. We'll see.
Waiting for the madness to calm down, and seeing what the destruction of our NIH, FDA, and Medicaid will yield as many of my stocks, BNGO included, have a dependency on these.
In times of madness, posting about stocks is futile, but still watching, daily, and day trading. We'll see.
Yes, that's correct.
A combination of the SP at the time, Q4 2023 sales which they will know about, and reimbursement which will kick in soon, will go into the decision as to which ratio they choose.
Too high a ratio and it will simply plummet - 25/1 is my guess if things are looking up.
A combination of the SP at the time, Q4 2023 sales which they will know about, and reimbursement which will kick in soon, will go into the decision as to which ratio they choose.
Too high a ratio and it will simply plummet - 25/1 is my guess if things are looking up.
November 26, 2024 at 5:49 PM
Yes, that's correct.
A combination of the SP at the time, Q4 2023 sales which they will know about, and reimbursement which will kick in soon, will go into the decision as to which ratio they choose.
Too high a ratio and it will simply plummet - 25/1 is my guess if things are looking up.
A combination of the SP at the time, Q4 2023 sales which they will know about, and reimbursement which will kick in soon, will go into the decision as to which ratio they choose.
Too high a ratio and it will simply plummet - 25/1 is my guess if things are looking up.
Cathie Wood has undeniably had an atrocious 2024 in terms of her high profile investments !
PacBio is an interesting one : their Revio is quite simply overpriced, and that's before next year's tariffs and inflation, so the outlook is poor + cheaper Oxford Nanopore is making serious waves ...
PacBio is an interesting one : their Revio is quite simply overpriced, and that's before next year's tariffs and inflation, so the outlook is poor + cheaper Oxford Nanopore is making serious waves ...
November 26, 2024 at 9:44 AM
Cathie Wood has undeniably had an atrocious 2024 in terms of her high profile investments !
PacBio is an interesting one : their Revio is quite simply overpriced, and that's before next year's tariffs and inflation, so the outlook is poor + cheaper Oxford Nanopore is making serious waves ...
PacBio is an interesting one : their Revio is quite simply overpriced, and that's before next year's tariffs and inflation, so the outlook is poor + cheaper Oxford Nanopore is making serious waves ...
$BNGO - Bionano
Bionano files a preliminary proxy for a Reverse Split (and further dilution) for continued listing on Nasdaq and, more importantly, for survival.
Whether you vote FOR or AGAINST will result in a depressed SP, but the better outcome is to vote FOR.
www.sec.gov/Archives/edg...
Bionano files a preliminary proxy for a Reverse Split (and further dilution) for continued listing on Nasdaq and, more importantly, for survival.
Whether you vote FOR or AGAINST will result in a depressed SP, but the better outcome is to vote FOR.
www.sec.gov/Archives/edg...
November 26, 2024 at 9:35 AM
$BNGO - Bionano
Bionano files a preliminary proxy for a Reverse Split (and further dilution) for continued listing on Nasdaq and, more importantly, for survival.
Whether you vote FOR or AGAINST will result in a depressed SP, but the better outcome is to vote FOR.
www.sec.gov/Archives/edg...
Bionano files a preliminary proxy for a Reverse Split (and further dilution) for continued listing on Nasdaq and, more importantly, for survival.
Whether you vote FOR or AGAINST will result in a depressed SP, but the better outcome is to vote FOR.
www.sec.gov/Archives/edg...
$BNGO - Bionano
Watching our industry : PacBio
PacBio Q3 2024 results.
PacBio's Q3 results reflect the [severe] H2 2024 downturn in the industry (save for Illumina).
www.pacb.com/press_releas...
Watching our industry : PacBio
PacBio Q3 2024 results.
PacBio's Q3 results reflect the [severe] H2 2024 downturn in the industry (save for Illumina).
www.pacb.com/press_releas...
November 25, 2024 at 9:48 PM
$BNGO - Bionano
Watching our industry : PacBio
PacBio Q3 2024 results.
PacBio's Q3 results reflect the [severe] H2 2024 downturn in the industry (save for Illumina).
www.pacb.com/press_releas...
Watching our industry : PacBio
PacBio Q3 2024 results.
PacBio's Q3 results reflect the [severe] H2 2024 downturn in the industry (save for Illumina).
www.pacb.com/press_releas...
$BNGO - Bionano
Watching our industry : 10x Genomics
Hamilton which has been providing workflow optimizations for pretty much all sequencing/genomic manufacturers (Illumina, PacBio, Bionano) finally "snares" 10x Genomics into a similar partnership.
www.marketscreener.com/quote/stock/...
Watching our industry : 10x Genomics
Hamilton which has been providing workflow optimizations for pretty much all sequencing/genomic manufacturers (Illumina, PacBio, Bionano) finally "snares" 10x Genomics into a similar partnership.
www.marketscreener.com/quote/stock/...
November 25, 2024 at 9:34 PM
$BNGO - Bionano
Watching our industry : 10x Genomics
Hamilton which has been providing workflow optimizations for pretty much all sequencing/genomic manufacturers (Illumina, PacBio, Bionano) finally "snares" 10x Genomics into a similar partnership.
www.marketscreener.com/quote/stock/...
Watching our industry : 10x Genomics
Hamilton which has been providing workflow optimizations for pretty much all sequencing/genomic manufacturers (Illumina, PacBio, Bionano) finally "snares" 10x Genomics into a similar partnership.
www.marketscreener.com/quote/stock/...
The 5 Belgium universities/hospitals were :
--------------------------------------------------------------
Ghent University Hospital, Ghent
Ghent University
University Hospital Leuven, Leuven
Antwerp University Hospital, Antwerp
University of Antwerp
www.nature.com/artic...
5/5
--------------------------------------------------------------
Ghent University Hospital, Ghent
Ghent University
University Hospital Leuven, Leuven
Antwerp University Hospital, Antwerp
University of Antwerp
www.nature.com/artic...
5/5
Full characterization of unresolved structural variation through long-read sequencing and optical genome mapping
Scientific Reports - Full characterization of unresolved structural variation through long-read sequencing and optical genome mapping
www.nature.com
November 25, 2024 at 9:14 PM
The 5 Belgium universities/hospitals were :
--------------------------------------------------------------
Ghent University Hospital, Ghent
Ghent University
University Hospital Leuven, Leuven
Antwerp University Hospital, Antwerp
University of Antwerp
www.nature.com/artic...
5/5
--------------------------------------------------------------
Ghent University Hospital, Ghent
Ghent University
University Hospital Leuven, Leuven
Antwerp University Hospital, Antwerp
University of Antwerp
www.nature.com/artic...
5/5
conditions.
Conclusion : both LRS and OGM need each other and when combined they provide a full and precise diagnosis not available through SOC molecular techniques.
4/5
Conclusion : both LRS and OGM need each other and when combined they provide a full and precise diagnosis not available through SOC molecular techniques.
4/5
November 25, 2024 at 9:14 PM
conditions.
Conclusion : both LRS and OGM need each other and when combined they provide a full and precise diagnosis not available through SOC molecular techniques.
4/5
Conclusion : both LRS and OGM need each other and when combined they provide a full and precise diagnosis not available through SOC molecular techniques.
4/5
The clinical scientists used Oxford Nanopore Long-Read sequencing and Optical Genome Mapping (OGM) and found that the combination of both these techniques provided a most powerful molecular diagnosis method which finally enabled them to fully characterize the SVs involved in these patients'
3/5
3/5
November 25, 2024 at 9:14 PM
The clinical scientists used Oxford Nanopore Long-Read sequencing and Optical Genome Mapping (OGM) and found that the combination of both these techniques provided a most powerful molecular diagnosis method which finally enabled them to fully characterize the SVs involved in these patients'
3/5
3/5
The paper details a study of 6 patients with Structural Variants unresolved through Standard of Care techniques (routine molecular techniques - Karyotyping, FISH, Short-Read Sequencing).
2/5
2/5
November 25, 2024 at 9:14 PM
The paper details a study of 6 patients with Structural Variants unresolved through Standard of Care techniques (routine molecular techniques - Karyotyping, FISH, Short-Read Sequencing).
2/5
2/5
$BNGO - Bionano
25-Nov-2024
5 Belgium universities and university hospitals publish a paper in the "NATURE" journal, titled :
"Full characterization of unresolved structural variation through long-read sequencing and Optical Genome Mapping"
1/5
25-Nov-2024
5 Belgium universities and university hospitals publish a paper in the "NATURE" journal, titled :
"Full characterization of unresolved structural variation through long-read sequencing and Optical Genome Mapping"
1/5
November 25, 2024 at 9:14 PM
$BNGO - Bionano
25-Nov-2024
5 Belgium universities and university hospitals publish a paper in the "NATURE" journal, titled :
"Full characterization of unresolved structural variation through long-read sequencing and Optical Genome Mapping"
1/5
25-Nov-2024
5 Belgium universities and university hospitals publish a paper in the "NATURE" journal, titled :
"Full characterization of unresolved structural variation through long-read sequencing and Optical Genome Mapping"
1/5
approach is desirable to overcome the limitations of the current Standard of Care.
onlinelibrary.wiley....
8/8
onlinelibrary.wiley....
8/8
November 25, 2024 at 6:52 PM
approach is desirable to overcome the limitations of the current Standard of Care.
onlinelibrary.wiley....
8/8
onlinelibrary.wiley....
8/8
So much so that in their conclusion the scientists stated :
"It is possible that technology such as OGM will identify similar events in other cases, and possibly help uncover previously unknown mechanisms of human disease."
The scientists conclude that in genetic diseases a multi-omics
7/8
"It is possible that technology such as OGM will identify similar events in other cases, and possibly help uncover previously unknown mechanisms of human disease."
The scientists conclude that in genetic diseases a multi-omics
7/8
November 25, 2024 at 6:52 PM
So much so that in their conclusion the scientists stated :
"It is possible that technology such as OGM will identify similar events in other cases, and possibly help uncover previously unknown mechanisms of human disease."
The scientists conclude that in genetic diseases a multi-omics
7/8
"It is possible that technology such as OGM will identify similar events in other cases, and possibly help uncover previously unknown mechanisms of human disease."
The scientists conclude that in genetic diseases a multi-omics
7/8
material from chromosome 17 undetected by Karyotyping or rGS. These novel mechanisms revealed by OGM were critical to the eventual diagnosis of the patient.
6/8
6/8
November 25, 2024 at 6:51 PM
material from chromosome 17 undetected by Karyotyping or rGS. These novel mechanisms revealed by OGM were critical to the eventual diagnosis of the patient.
6/8
6/8
OGM not only confirmed the clinicians' suspicions but, additionally, contrary to the SVs suggested by Karyotyping and rGS (rapid Genome Sequencing) demonstrated the presence of an unbalanced translocation involving chromosomes 22 and 17, with loss of material from chromosome 22, and a gain of
5/8
5/8
November 25, 2024 at 6:51 PM
OGM not only confirmed the clinicians' suspicions but, additionally, contrary to the SVs suggested by Karyotyping and rGS (rapid Genome Sequencing) demonstrated the presence of an unbalanced translocation involving chromosomes 22 and 17, with loss of material from chromosome 22, and a gain of
5/8
5/8
At this point they turned to OGM for a more precise molecular diagnosis.
4/8
4/8
November 25, 2024 at 6:51 PM
At this point they turned to OGM for a more precise molecular diagnosis.
4/8
4/8
In this particular case, a patient's observable signs were so severe that, when taking into account that they had already discovered a previously unknown translocation, the clinicians suspected there might be additional breakpoints and/or translocations involved.
3/8
3/8
November 25, 2024 at 6:51 PM
In this particular case, a patient's observable signs were so severe that, when taking into account that they had already discovered a previously unknown translocation, the clinicians suspected there might be additional breakpoints and/or translocations involved.
3/8
3/8
is a genetic disorder which can cause a wide range of symptoms varying in severity. These symptoms could include global developmental delay/intellectual disability, motor skills deficits, delayed or absent speech, autism spectrum disorder, and minor dysmorphic features.
2/8
2/8
November 25, 2024 at 6:51 PM
is a genetic disorder which can cause a wide range of symptoms varying in severity. These symptoms could include global developmental delay/intellectual disability, motor skills deficits, delayed or absent speech, autism spectrum disorder, and minor dysmorphic features.
2/8
2/8
$BNGO - Bionano
13-Nov-2024
The Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH, publishes a paper titled :
"Optical Genome Mapping (OGM) Identifies Multiple Structural Variants in a Case With Atypical Phelan-McDermid Syndrome"
The Phelan-McDermid Syndrome
1/8
13-Nov-2024
The Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH, publishes a paper titled :
"Optical Genome Mapping (OGM) Identifies Multiple Structural Variants in a Case With Atypical Phelan-McDermid Syndrome"
The Phelan-McDermid Syndrome
1/8
November 25, 2024 at 6:51 PM
$BNGO - Bionano
13-Nov-2024
The Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH, publishes a paper titled :
"Optical Genome Mapping (OGM) Identifies Multiple Structural Variants in a Case With Atypical Phelan-McDermid Syndrome"
The Phelan-McDermid Syndrome
1/8
13-Nov-2024
The Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH, publishes a paper titled :
"Optical Genome Mapping (OGM) Identifies Multiple Structural Variants in a Case With Atypical Phelan-McDermid Syndrome"
The Phelan-McDermid Syndrome
1/8
IGNORE - 20 minutes later all good throughout.
Not sure what happened, but all good !
Thank You !
Not sure what happened, but all good !
Thank You !
November 25, 2024 at 6:19 PM
IGNORE - 20 minutes later all good throughout.
Not sure what happened, but all good !
Thank You !
Not sure what happened, but all good !
Thank You !
@jay.bsky.team
Automated Translation - I want to turn it off !
Suddenly today (25-Nov-2024) everything is in English.
I speak 3 languages & can understand another 4. I follow threads from various countries and do not want their posts to be automatically translated for me !
Correction Please !
Automated Translation - I want to turn it off !
Suddenly today (25-Nov-2024) everything is in English.
I speak 3 languages & can understand another 4. I follow threads from various countries and do not want their posts to be automatically translated for me !
Correction Please !
November 25, 2024 at 6:02 PM
@jay.bsky.team
Automated Translation - I want to turn it off !
Suddenly today (25-Nov-2024) everything is in English.
I speak 3 languages & can understand another 4. I follow threads from various countries and do not want their posts to be automatically translated for me !
Correction Please !
Automated Translation - I want to turn it off !
Suddenly today (25-Nov-2024) everything is in English.
I speak 3 languages & can understand another 4. I follow threads from various countries and do not want their posts to be automatically translated for me !
Correction Please !