The Gregory Lab @ DukeU
@gregorylab.bskyverified.social
The Gregory lab @DukeU studies disease mechanism using scRNAseq & spatial molecular technologies. Focus on brain tumors, Alzheimer's and MS 🧠 Home to the Molecular Genomics Core (MGC) - https://dmpi.duke.edu/cores/molecular-genomics-core-mgc
Pinned
dmpi.duke.edu
We are the the Gregory lab @dukemedschool.bsky.social, studying disease mechanism through scRNAseq & spatial molecular technologies, focusing on brain tumors, Alzheimer's and MS 🧠
Also home to the Molecular Genomics Core (MGC)- for more info pls visit our website: dmpi.duke.edu/cores/molecu... 🧬🧠💻
Also home to the Molecular Genomics Core (MGC)- for more info pls visit our website: dmpi.duke.edu/cores/molecu... 🧬🧠💻
Reposted by The Gregory Lab @ DukeU
Recent review from HTAN. Linghua Wang with a timely review on spatial omic technologies Cancer Cell. www.cell.com/cancer-cell/...
Spatial omics at the forefront: emerging technologies, analytical innovations, and clinical applications
Liu et al. review how spatial omics technologies reveal the organization, interaction,
and evolution of tumor cells and their microenvironment within tissues. They highlight
analytical advances that t...
www.cell.com
January 26, 2026 at 5:31 PM
Recent review from HTAN. Linghua Wang with a timely review on spatial omic technologies Cancer Cell. www.cell.com/cancer-cell/...
We are thrilled to share the 1st pub out of the #DukeMGC. Congrats to Lab Analyst Ellora Haukenfrers' on your 1st first author paper!
We present 'A platform-agnostic evaluation of non-formalin fixed #singlecell RNA technologies'
#benchmarking #scRNAseq
www.biorxiv.org/content/10.6...
We present 'A platform-agnostic evaluation of non-formalin fixed #singlecell RNA technologies'
#benchmarking #scRNAseq
www.biorxiv.org/content/10.6...
January 29, 2026 at 2:42 AM
We are thrilled to share the 1st pub out of the #DukeMGC. Congrats to Lab Analyst Ellora Haukenfrers' on your 1st first author paper!
We present 'A platform-agnostic evaluation of non-formalin fixed #singlecell RNA technologies'
#benchmarking #scRNAseq
www.biorxiv.org/content/10.6...
We present 'A platform-agnostic evaluation of non-formalin fixed #singlecell RNA technologies'
#benchmarking #scRNAseq
www.biorxiv.org/content/10.6...
Upcoming on Feb 4, the next #DukeSCIRIP seminar! Featuring talks from Lauren Parker of the Karra lab & Hamayl Afzal.
For more information or to contact #DukeSCIRIP, please visit out website: dmpi.duke.edu/duke-single-...
For more information or to contact #DukeSCIRIP, please visit out website: dmpi.duke.edu/duke-single-...
January 20, 2026 at 5:37 PM
Upcoming on Feb 4, the next #DukeSCIRIP seminar! Featuring talks from Lauren Parker of the Karra lab & Hamayl Afzal.
For more information or to contact #DukeSCIRIP, please visit out website: dmpi.duke.edu/duke-single-...
For more information or to contact #DukeSCIRIP, please visit out website: dmpi.duke.edu/duke-single-...
Reposted by The Gregory Lab @ DukeU
3 papers in Cell @cellpress.bsky.social today exploring the mechanistic connection between Epstein-Barr virus and multiple sclerosis #MultipleSclerosis
cell.com/cell/fulltex...
cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
cell.com/cell/fulltex...
cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
January 13, 2026 at 4:25 PM
3 papers in Cell @cellpress.bsky.social today exploring the mechanistic connection between Epstein-Barr virus and multiple sclerosis #MultipleSclerosis
cell.com/cell/fulltex...
cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
cell.com/cell/fulltex...
cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
Reposted by The Gregory Lab @ DukeU
I am recruiting a postdoc focused on analysis of 'omic' data with the goal of identifying cell types that modulate GBM predisposition.
An ideal candidate would have expertise in analysis of:
• Single cell/spatial sequencing.
• Bulk RNA
• WXS
• Genotyping array.
careers.duke.edu/job/Durham-P...
An ideal candidate would have expertise in analysis of:
• Single cell/spatial sequencing.
• Bulk RNA
• WXS
• Genotyping array.
careers.duke.edu/job/Durham-P...
POSTDOCTORAL ASSOCIATE
POSTDOCTORAL ASSOCIATE
careers.duke.edu
January 9, 2026 at 4:10 PM
I am recruiting a postdoc focused on analysis of 'omic' data with the goal of identifying cell types that modulate GBM predisposition.
An ideal candidate would have expertise in analysis of:
• Single cell/spatial sequencing.
• Bulk RNA
• WXS
• Genotyping array.
careers.duke.edu/job/Durham-P...
An ideal candidate would have expertise in analysis of:
• Single cell/spatial sequencing.
• Bulk RNA
• WXS
• Genotyping array.
careers.duke.edu/job/Durham-P...
Reposted by The Gregory Lab @ DukeU
That's a wrap on another year in the Gregory lab! 2025 was filled with many hours of hard work in the lab & R Studio, with some fun along the way.
Cheers to 2026 from all of us - we can't wait to show you what we've been working on this year! 🥂🧬🧠
#SingleCell #SpatialOmics
Cheers to 2026 from all of us - we can't wait to show you what we've been working on this year! 🥂🧬🧠
#SingleCell #SpatialOmics
December 30, 2025 at 4:34 PM
That's a wrap on another year in the Gregory lab! 2025 was filled with many hours of hard work in the lab & R Studio, with some fun along the way.
Cheers to 2026 from all of us - we can't wait to show you what we've been working on this year! 🥂🧬🧠
#SingleCell #SpatialOmics
Cheers to 2026 from all of us - we can't wait to show you what we've been working on this year! 🥂🧬🧠
#SingleCell #SpatialOmics
Reposted by The Gregory Lab @ DukeU
"using single-cell transcriptomes from 1,271 patients across 26 cancer types, we compile a TME cellular atlas, leading to the identification of recurrent cell states and multicellular modules across cancer types." www.biorxiv.org/content/10....
December 30, 2025 at 3:15 PM
"using single-cell transcriptomes from 1,271 patients across 26 cancer types, we compile a TME cellular atlas, leading to the identification of recurrent cell states and multicellular modules across cancer types." www.biorxiv.org/content/10....
Happy Holidays from the Gregory Lab 🎀🥂
December 26, 2025 at 2:03 PM
Happy Holidays from the Gregory Lab 🎀🥂
January 7th 2-1pm in MSRBIII or online, #DukeSCIRIP seminar series continues!
@epigenometech.bsky.social's Chris Hartle will be presenting the talk '‘Deciphering Single-Cell Chromatin Landscapes in the Human Immune System: A First Look’ 🧬
For more information: dmpi.duke.edu/duke-single-...
@epigenometech.bsky.social's Chris Hartle will be presenting the talk '‘Deciphering Single-Cell Chromatin Landscapes in the Human Immune System: A First Look’ 🧬
For more information: dmpi.duke.edu/duke-single-...
December 19, 2025 at 8:17 PM
January 7th 2-1pm in MSRBIII or online, #DukeSCIRIP seminar series continues!
@epigenometech.bsky.social's Chris Hartle will be presenting the talk '‘Deciphering Single-Cell Chromatin Landscapes in the Human Immune System: A First Look’ 🧬
For more information: dmpi.duke.edu/duke-single-...
@epigenometech.bsky.social's Chris Hartle will be presenting the talk '‘Deciphering Single-Cell Chromatin Landscapes in the Human Immune System: A First Look’ 🧬
For more information: dmpi.duke.edu/duke-single-...
Yesterday, the Gregory lab had our annual holiday lunch & white elephant gift exchange
A great time was had by all! After all, we have holiday cheer in our DNA (and on our lab cart)🧬🎄🕎
A great time was had by all! After all, we have holiday cheer in our DNA (and on our lab cart)🧬🎄🕎
December 17, 2025 at 9:15 PM
Yesterday, the Gregory lab had our annual holiday lunch & white elephant gift exchange
A great time was had by all! After all, we have holiday cheer in our DNA (and on our lab cart)🧬🎄🕎
A great time was had by all! After all, we have holiday cheer in our DNA (and on our lab cart)🧬🎄🕎
Today, #DukeMGC gave a talk & poster presentation on our available services at the #Duke Precision Genomics Collaboratory! We love the opportunity to share the work we do... 🧬🧠
Interested in learning more about MGC services? Please visit our website: dmpi.duke.edu/cores/molecu...
Interested in learning more about MGC services? Please visit our website: dmpi.duke.edu/cores/molecu...
December 12, 2025 at 7:27 PM
Today, #DukeMGC gave a talk & poster presentation on our available services at the #Duke Precision Genomics Collaboratory! We love the opportunity to share the work we do... 🧬🧠
Interested in learning more about MGC services? Please visit our website: dmpi.duke.edu/cores/molecu...
Interested in learning more about MGC services? Please visit our website: dmpi.duke.edu/cores/molecu...
Lauren also got the chance to catch up with her old lab (#HugoGuerreroLab)! It was great to see familiar faces, picturesque scenery & exciting new #NeuroOncology developments
December 9, 2025 at 3:02 PM
Lauren also got the chance to catch up with her old lab (#HugoGuerreroLab)! It was great to see familiar faces, picturesque scenery & exciting new #NeuroOncology developments
Gregory lab #PhD student, Lauren Whaley Powers, attended #SNO25 in beautiful Honolulu & presented her poster:
'Integrative #SingleNuclei #SpatialTranscriptomic profiling of primary and recurrent human #GBM reveals cell-type specific #EGFRvIII expression & #ANXA1 signaling axis' 🧠🧬🔬💻🌺
'Integrative #SingleNuclei #SpatialTranscriptomic profiling of primary and recurrent human #GBM reveals cell-type specific #EGFRvIII expression & #ANXA1 signaling axis' 🧠🧬🔬💻🌺
December 9, 2025 at 2:58 PM
Gregory lab #PhD student, Lauren Whaley Powers, attended #SNO25 in beautiful Honolulu & presented her poster:
'Integrative #SingleNuclei #SpatialTranscriptomic profiling of primary and recurrent human #GBM reveals cell-type specific #EGFRvIII expression & #ANXA1 signaling axis' 🧠🧬🔬💻🌺
'Integrative #SingleNuclei #SpatialTranscriptomic profiling of primary and recurrent human #GBM reveals cell-type specific #EGFRvIII expression & #ANXA1 signaling axis' 🧠🧬🔬💻🌺
New publication by our student, Odmaa Bayaraa: 'Multi-region #SpatialTranscriptomics reveals region specific differences in response to amyloid beta (Aβ) plaque induced changes in #Alzheimers disease (#AD)'
So proud of this work and of Odmaa! Check it out 🧬🧠
pubmed.ncbi.nlm.nih.gov/41318546/
So proud of this work and of Odmaa! Check it out 🧬🧠
pubmed.ncbi.nlm.nih.gov/41318546/
Multi-region spatial transcriptomics reveals region specific differences in response to amyloid beta (Aβ) plaque induced changes in Alzheimer's disease (AD) - PubMed
Our results demonstrate the value of simultaneously profiling AD-omic and spatial modalities in multiple regions to elucidate how cortical region-specific differences contribute to selective vulnerability and resilience during neurodegeneration. These cortical region and Aβ microenvironment-specific …
pubmed.ncbi.nlm.nih.gov
December 8, 2025 at 1:47 PM
New publication by our student, Odmaa Bayaraa: 'Multi-region #SpatialTranscriptomics reveals region specific differences in response to amyloid beta (Aβ) plaque induced changes in #Alzheimers disease (#AD)'
So proud of this work and of Odmaa! Check it out 🧬🧠
pubmed.ncbi.nlm.nih.gov/41318546/
So proud of this work and of Odmaa! Check it out 🧬🧠
pubmed.ncbi.nlm.nih.gov/41318546/
Reposted by The Gregory Lab @ DukeU
Reposted by The Gregory Lab @ DukeU
We are looking for a bioinformatics postdoc to join our group! Apply here 👇👇👇
www.jobs.ac.uk/job/DPQ109/p...
www.jobs.ac.uk/job/DPQ109/p...
December 1, 2025 at 11:14 AM
We are looking for a bioinformatics postdoc to join our group! Apply here 👇👇👇
www.jobs.ac.uk/job/DPQ109/p...
www.jobs.ac.uk/job/DPQ109/p...
Happening next week!!
12/3 12-1pm in MSRBIII or online, #DukeSCIRIP seminar series continues!
Feat. talks from Shane O'Neil of the @filianolab.bsky.social and Huifang Ma of the #DukeBiostats Ji lab 🧬
Interested in attending virtually or presenting? Visit our webpage for more information: dmpi.duke.edu/duke-single-...
Feat. talks from Shane O'Neil of the @filianolab.bsky.social and Huifang Ma of the #DukeBiostats Ji lab 🧬
Interested in attending virtually or presenting? Visit our webpage for more information: dmpi.duke.edu/duke-single-...
November 28, 2025 at 6:28 PM
Happening next week!!
Reposted by The Gregory Lab @ DukeU
Join us:
With @abigailsuwala.bsky.social we are looking for a postdoc to drive our spatial transcriptomics analysis efforts of brain tumours.
If you enjoy multidisciplinary biomedical research, big data and coding, you are in the right place.
karriere.klinikum.uni-heidelberg.de/index.php?ac...
With @abigailsuwala.bsky.social we are looking for a postdoc to drive our spatial transcriptomics analysis efforts of brain tumours.
If you enjoy multidisciplinary biomedical research, big data and coding, you are in the right place.
karriere.klinikum.uni-heidelberg.de/index.php?ac...
November 28, 2025 at 2:11 PM
Join us:
With @abigailsuwala.bsky.social we are looking for a postdoc to drive our spatial transcriptomics analysis efforts of brain tumours.
If you enjoy multidisciplinary biomedical research, big data and coding, you are in the right place.
karriere.klinikum.uni-heidelberg.de/index.php?ac...
With @abigailsuwala.bsky.social we are looking for a postdoc to drive our spatial transcriptomics analysis efforts of brain tumours.
If you enjoy multidisciplinary biomedical research, big data and coding, you are in the right place.
karriere.klinikum.uni-heidelberg.de/index.php?ac...
Last week, Gregory lab #PhD student Emma Hatchell attended @sfn.org #Sfn2025 in beautiful San Diego and presented a poster!
"Spatial Profiling of #Herpesvirus Transcripts in #MultipleSclerosis Spinal Cord Lesions Using #Xenium In Situ Analysis" 🧬
"Spatial Profiling of #Herpesvirus Transcripts in #MultipleSclerosis Spinal Cord Lesions Using #Xenium In Situ Analysis" 🧬
November 24, 2025 at 7:53 PM
Last week, Gregory lab #PhD student Emma Hatchell attended @sfn.org #Sfn2025 in beautiful San Diego and presented a poster!
"Spatial Profiling of #Herpesvirus Transcripts in #MultipleSclerosis Spinal Cord Lesions Using #Xenium In Situ Analysis" 🧬
"Spatial Profiling of #Herpesvirus Transcripts in #MultipleSclerosis Spinal Cord Lesions Using #Xenium In Situ Analysis" 🧬
12/3 12-1pm in MSRBIII or online, #DukeSCIRIP seminar series continues!
Feat. talks from Shane O'Neil of the @filianolab.bsky.social and Huifang Ma of the #DukeBiostats Ji lab 🧬
Interested in attending virtually or presenting? Visit our webpage for more information: dmpi.duke.edu/duke-single-...
Feat. talks from Shane O'Neil of the @filianolab.bsky.social and Huifang Ma of the #DukeBiostats Ji lab 🧬
Interested in attending virtually or presenting? Visit our webpage for more information: dmpi.duke.edu/duke-single-...
November 20, 2025 at 6:52 PM
12/3 12-1pm in MSRBIII or online, #DukeSCIRIP seminar series continues!
Feat. talks from Shane O'Neil of the @filianolab.bsky.social and Huifang Ma of the #DukeBiostats Ji lab 🧬
Interested in attending virtually or presenting? Visit our webpage for more information: dmpi.duke.edu/duke-single-...
Feat. talks from Shane O'Neil of the @filianolab.bsky.social and Huifang Ma of the #DukeBiostats Ji lab 🧬
Interested in attending virtually or presenting? Visit our webpage for more information: dmpi.duke.edu/duke-single-...
Please vote for the #DukeMGC wet lab's costume ('That Rat’s a Real Muenster’) in the 2025 Duke Costume Contest!! Each like = 1 vote
www.facebook.com/workingatduke/
www.facebook.com/workingatduke/
November 4, 2025 at 9:07 PM
Please vote for the #DukeMGC wet lab's costume ('That Rat’s a Real Muenster’) in the 2025 Duke Costume Contest!! Each like = 1 vote
www.facebook.com/workingatduke/
www.facebook.com/workingatduke/
Gregory lab #PhD student, Lauren Whaley's work on post-mortem samples from patient-donors, in partnership with the #MarkHughesFoundation
Thank you #MHF for your generosity! 🧠🧬
markhughesfoundation.com.au/latest-resea...
#BrainTumors #GBM #Biobank #Glioblastoma #SpatialOmics
Thank you #MHF for your generosity! 🧠🧬
markhughesfoundation.com.au/latest-resea...
#BrainTumors #GBM #Biobank #Glioblastoma #SpatialOmics
Generous post-mortem donations spark international collaboration | Mark Hughes Foundation
We have a very unique asset in the Mark Hughes Foundation Biobank – a post-mortem collection from patient-donors. Funded through the generosity of the Mark Hughes Foundation this one-of-a-kind asset c...
markhughesfoundation.com.au
November 3, 2025 at 3:48 PM
Gregory lab #PhD student, Lauren Whaley's work on post-mortem samples from patient-donors, in partnership with the #MarkHughesFoundation
Thank you #MHF for your generosity! 🧠🧬
markhughesfoundation.com.au/latest-resea...
#BrainTumors #GBM #Biobank #Glioblastoma #SpatialOmics
Thank you #MHF for your generosity! 🧠🧬
markhughesfoundation.com.au/latest-resea...
#BrainTumors #GBM #Biobank #Glioblastoma #SpatialOmics
Hope you weren't planning any rat studies soon...
This year, the #DukeMGC dressed up as a lab rat & cheese!! Happy #Halloween & stay cheesy everyone 🧀🐀🎃
This year, the #DukeMGC dressed up as a lab rat & cheese!! Happy #Halloween & stay cheesy everyone 🧀🐀🎃
October 31, 2025 at 6:49 PM
Hope you weren't planning any rat studies soon...
This year, the #DukeMGC dressed up as a lab rat & cheese!! Happy #Halloween & stay cheesy everyone 🧀🐀🎃
This year, the #DukeMGC dressed up as a lab rat & cheese!! Happy #Halloween & stay cheesy everyone 🧀🐀🎃
Ms. Casey, Mark S., and Dylan want to remind you that "the work is mysterious and important"
Please enjoy Gregory lab PhD. students' #Severance costume 🧠👻
Please enjoy Gregory lab PhD. students' #Severance costume 🧠👻
October 31, 2025 at 5:11 PM
Ms. Casey, Mark S., and Dylan want to remind you that "the work is mysterious and important"
Please enjoy Gregory lab PhD. students' #Severance costume 🧠👻
Please enjoy Gregory lab PhD. students' #Severance costume 🧠👻