Heli Jeskanen
banner
helij.bsky.social
Heli Jeskanen
@helij.bsky.social
Life full of molecular medicine, neuroscience and weightlifting 🧬🧠🏋🏼‍♀️ Doctoral Researcher at University of Eastern Finland #alzheimer #microglia
Reposted by Heli Jeskanen
The protective PLCG2 variants delay Alzheimer's disease onset age in APOE ϵ4 carriers https://www.medrxiv.org/content/10.1101/2025.09.22.25336304v1
September 25, 2025 at 9:40 PM
Exciting news! Our study ”The protective PLCγ2-P522R variant mitigates Alzheimer’s disease-associated pathologies by enhancing beneficial microglial functions” is now published in the Journal of Neuroinflammation! 🧠✨

Check it out 🤓👇🏻

jneuroinflammation.biomedcentral.com/articles/10....
The protective PLCγ2-P522R variant mitigates Alzheimer’s disease-associated pathologies by enhancing beneficial microglial functions - Journal of Neuroinflammation
Background Phospholipase C gamma 2, proline 522 to arginine (PLCγ2-P522R) is a protective variant that reduces the risk of Alzheimer’s disease (AD). Recently, it was shown to mitigate β-amyloid pathol...
jneuroinflammation.biomedcentral.com
March 5, 2025 at 9:32 AM