Paul Scotti
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humanscotti.bsky.social
Paul Scotti
@humanscotti.bsky.social
Research scientist at Princeton Neuroscience Institute | Ex Stability AI
Reposted by Paul Scotti
I have EXCITING news:

I've started a company!

Introducing Sophont

We’re building open multimodal foundation models for the future of healthcare. We need a DeepSeek for medical AI, and @sophontai.bsky.social will be that company!

Check out our website & blog post for more info (link below)
April 1, 2025 at 8:49 PM
NeuroAI papers that caught my interest last month:

brain-image alignment | brain scaling laws | brain-to-text decoding

Sharing quick takeaways on these papers alongside raw technical notes: paulscotti.substack.com/p/neuroai-im...
March 14, 2025 at 2:24 PM
Reposted by Paul Scotti
How can large-scale models + datasets revolutionize neuroscience 🧠🤖🌐? We are excited to announce our workshop: “Building a foundation model for the brain: datasets, theory, and models” at @cosynemeeting.bsky.social #COSYNE2025. Join us in Mont-Tremblant, Canada from March 31 – April 1!
March 10, 2025 at 7:55 PM
I resigned from Stability AI after over a year working as Head of NeuroAI.

A personal retrospective on my journey with open science communities and how Stability AI’s role in the “science-in-the-open” movement was such a pivotal phenomenon: paulscotti.com/blog/leaving...
Leaving Stability
A personal retrospective on leaving Stability AI and my journey with open science communities, OnNeuro, LAION, and MedARC.
paulscotti.com
February 9, 2025 at 1:57 PM
Transformers are usually considered biologically implausible

but maybe the brain actually does do self-attention + feed-forward operations

astrocytes could enable a biologically plausible solution to transformer mechanisms in the brain

www.pnas.org/doi/pdf/10.1...
www.pnas.org
December 8, 2024 at 3:35 PM
Reposted by Paul Scotti
It’s really heart breaking to realize just how much our short horizon, outcome focused funding cycles hurt science. We could do so much more if we could invest in people long term. Staff scientist positions and an ecosystem to support them are direly needed.
December 3, 2024 at 11:31 PM
Reposted by Paul Scotti
This is big: in collaboration with E11 Bio and @andrewcpayne.bsky.social, we are announcing today a new way to map brain circuits at scale. With improvements in AI and microscopy I think whole brain mouse and maybe human brain mapping will be feasible in ~5-10 years. 1/
🧪 E11 Bio is excited to share a major step towards brain mapping at 100x lower cost, making whole-brain connectomics at human & mouse scale feasible (🧠→🔬→💻). Critical for curing brain disorders, building human-like AI systems, and even simulating human brains.

Read more: e11.bio/news/roadmap
December 3, 2024 at 3:48 PM
An actionable comprehensive paper regarding roadmaps for NeuroAI, highly recommend a read esp if any of the following topics sound interesting:

Foundation brain models

Sensory and embodied digital twins

Brain data to improve AI models

Neuro-inspired mech. interpretability
Excited to release what we’ve been working on at Amaranth Foundation, our latest whitepaper, NeuroAI for AI safety! A detailed, ambitious roadmap for how neuroscience research can help build safer AI systems while accelerating both virtual neuroscience and neurotech. 1/N
December 3, 2024 at 5:50 PM
🧠👁️ Our MindEye2 preprint is out!

We reconstruct seen images from fMRI activity using only 1 hour of training data.

This is possible by first pretraining a shared-subject model using other people's data, and then fine-tuning on a held-out subject with only 1 hr of data.

arxiv.org/abs/2403.11207
March 19, 2024 at 12:40 PM
Happy to share that I am now Head of Neuroimaging at Stability AI!

My role is to lead the MedARC Neuroimaging & AI Lab: medarc.ai/fmri

The lab is remote, open-source, and open to the public to join. Tons of potential to rethink what a research lab is and benefit from crowd-sourced intelligence.
Notion – The all-in-one workspace for your notes, tasks, wikis, and databases.
A new tool that blends your everyday work apps into one. It's the all-in-one workspace for you and your team
medarc.ai
November 14, 2023 at 12:50 AM
Our MindEye fMRI-to-Image paper got accepted as spotlight for #NeurIPS2023! See you in New Orleans, will be my first time attending NeurIPS :)

Updated camera ready paper is also now live on arxiv: arxiv.org/abs/2305.182...

Includes new expts, appendix figures, more references to other work 🧠📈
October 10, 2023 at 1:42 PM