Polypyrrole (PPy) is a promising conducting polymer for supercapacitor electrodes, but its structural degradation during repeated cycling limits its long-term stability. Here, we report the design of ...

In the past two decades, antibody–drug conjugates (ADCs) have emerged as highly effective targeted therapeutics against cancers. One current path to improve ADCs is to increase the amount of cytotoxic...

Complexes of macrocyclic ligands are routinely used as MRI contrast agents and radionuclide carriers for PET and SPECT diagnostics and radiotherapy. This study explores the structural and electronic e...

Poly(2-isopropenyl-2-oxazoline) (PIPOx) is a versatile postpolymerization modification platform, yet its reactions have so far been limited to direct additions of thiols and carboxylic acids with variable efficiency. Here, we show that the reaction of PIPOx with 2,3,4,5,6-pentafluorothiophenol (PFTP) rapidly and cleanly generates poly(N-(2-((perfluorophenyl)thio)ethyl)methacrylamide) (PPFPTEMA), a highly reactive precursor for para-fluoro-thiol (PFT) click chemistry, featuring fast kinetics, equimolarity, orthogonality, and facile product isolation. A wide array of commercially available thiols react quantitatively and selectively with PPFPTEMA, enabling the synthesis of well-defined polymethacrylamides with diverse side-chain functionalities, including ionizable groups, supramolecular motifs, natural compounds, drugs, fluorescent tags, and polymers. The high efficiency and orthogonality of the PFT click reaction also allow multiple thiols to be combined to precisely tailor the copolymer composition. Importantly, when using thiol excess, the pentafluorophenyl groups in PPFPTEMA are found to undergo multiple substitutions under mild conditions, offering an unprecedented level of synthetic flexibility for designing functional polymers. Overall, this work seamlessly integrates PFT click chemistry into the PIPOx platform, establishing a powerful modular framework for the precision synthesis of multifunctional polymers.

The ethylene-propylene-diene rubber (EPDM)-based hybrid nanocomposites with graphene nanoplatelets (GnPs) and multiwall carbon nanotubes (MWCNTs) were prepared by melt mixing followed by compression m...

Cross-linked poly(alkylene citates) (cPAC) based on 1,6-hexanediol (cPHC) and 1,8-octanediol (cPOC) and modified with 0.4, 0.8 and 1.6% w/w l-glutathione (GSH) were synthesized as potential materials ...

Conducting polypyrrole (PPy) synthesized through oxidative chemical vapor deposition (oCVD) on thermally activated carbon cloth was utilized in producing a PPy-based electrode for high-performing supercapacitors. The PPy deposition time was varied at 30, 60, and 90 min, creating CPPy30, CPPy60, and CPPy90 active materials, and their electrochemical properties were studied. CPPy90 has the highest capacitance at 299.5 mF cm–2 (1497.7 mF cm–3) with its Raman spectra showing a high doping degree, which contributed to its good capacitive behavior. Symmetric (CPPy90//CPPy90) and asymmetric (AC//CPPy90) supercapacitors were fabricated as prototypes. CPPy90//CPPy90 exhibited a maximum capacitance of 46.0 mF cm–2 (115.0 mF cm–3) with an energy density of 4.1 mWh cm–2 (1.0 mWh cm–3) at a power density of 80 mW cm–2 (20 mW cm–3). The electrochemical capacitance of AC//CPPy90 was 168.2 mF cm–2 (560.6 mF cm–3) with an energy density of 15.0 mWh cm–2 (5.0 mWh cm–3) at 80 mW cm–2 (26.7 mW cm–3) power density. AC//CPPy90 has shown better energy storage performance than CPPy90//CPPy90. Therefore, in this study, the low impedance and high capacitance of oCVD-prepared CPPy90 have promoted the development of symmetric and asymmetric PPy-based supercapacitors with good electrochemical performance.

Purpose Retinal Pigment Epithelial (RPE) cells perform critical functions in the visual cycle. Their melanin pigmentation, which is organized into specialized compartments – melanosomes, is highly c...

Poly(diol citrates) present good electrospinning processability when used with PLA and exhibit increased hydrophilicity and surface adhesion forces compared to PLA nonwovens. Diol chain length influe...