IonOpticks
@ionopticks.bsky.social
https://ionopticks.com
IonOpticks designs and manufactures the world's best chromatography: state-of-the-art, high-performance packed emitter columns that radically improve results from LC-MS-based research.
#massspec #proteomics #teammassspec
IonOpticks designs and manufactures the world's best chromatography: state-of-the-art, high-performance packed emitter columns that radically improve results from LC-MS-based research.
#massspec #proteomics #teammassspec
We’re proud to support the Queensland Mass Spectrometry Symposium 2026, which kicks off next week at the Global Change Institute.
Fabrice, our Distribution Channel Manager - APACI, will attend on both days, January 28-29. If you’ll be there, see if you can spot Fabrice - he'd love to connect
Fabrice, our Distribution Channel Manager - APACI, will attend on both days, January 28-29. If you’ll be there, see if you can spot Fabrice - he'd love to connect
January 20, 2026 at 4:37 AM
We’re proud to support the Queensland Mass Spectrometry Symposium 2026, which kicks off next week at the Global Change Institute.
Fabrice, our Distribution Channel Manager - APACI, will attend on both days, January 28-29. If you’ll be there, see if you can spot Fabrice - he'd love to connect
Fabrice, our Distribution Channel Manager - APACI, will attend on both days, January 28-29. If you’ll be there, see if you can spot Fabrice - he'd love to connect
With February fast approaching, we’re looking forward to being part of the Fourth Ubuntu Proteomics Summer School in George, South Africa.
Join Dr. @jsandow.bsky.social Jarrod Sandow to learn all about chromatography and its crucial applications in proteomics.
Join Dr. @jsandow.bsky.social Jarrod Sandow to learn all about chromatography and its crucial applications in proteomics.
#teamio #upss2026 #teammassspec | Ubuntu Proteomics Summer School
We are excited to welcome back #TeamIO as a sponsor of #UPSS2026! IonOpticks specializes in developing advanced chromatography columns for use in LC-MS, enabling and advancing proteomics driven resear...
www.linkedin.com
January 19, 2026 at 6:01 AM
With February fast approaching, we’re looking forward to being part of the Fourth Ubuntu Proteomics Summer School in George, South Africa.
Join Dr. @jsandow.bsky.social Jarrod Sandow to learn all about chromatography and its crucial applications in proteomics.
Join Dr. @jsandow.bsky.social Jarrod Sandow to learn all about chromatography and its crucial applications in proteomics.
Dr. Xiang Zheng, Asst. Prof. at Aarhus University, extracts 1,000s of proteins from individual cell types to map cancer's complex ecosystem. Working with precious clinical samples where material is limited, he shared how column reliability enables his spatial proteomics breakthroughs.
bit.ly/42jl7Ux
bit.ly/42jl7Ux
January 19, 2026 at 2:21 AM
Dr. Xiang Zheng, Asst. Prof. at Aarhus University, extracts 1,000s of proteins from individual cell types to map cancer's complex ecosystem. Working with precious clinical samples where material is limited, he shared how column reliability enables his spatial proteomics breakthroughs.
bit.ly/42jl7Ux
bit.ly/42jl7Ux
Three weeks left until the 31st Annual Lorne Proteomics Symposium 2026 at Mantra Lorne in Victoria. We’re at booth 14 so swing by and chat to us about how our product pipeline can elevate your research, including a closer look at our new NanoShield™ reversed-flush C18 trap columns. See you in Lorne.
January 13, 2026 at 3:27 AM
Three weeks left until the 31st Annual Lorne Proteomics Symposium 2026 at Mantra Lorne in Victoria. We’re at booth 14 so swing by and chat to us about how our product pipeline can elevate your research, including a closer look at our new NanoShield™ reversed-flush C18 trap columns. See you in Lorne.
New globally representative vaccine screening method from the Foster lab uses 30 diverse cell lines + LC-MS/MS to identify broadly protective antigens. Analysis via EASY-nLC 1000 + timsTOF Pro with Aurora Ultimate 25x75 CSI column, identified 18 common binding motifs.
bit.ly/4qQruIe
bit.ly/4qQruIe
Preprint: A globally representative immunopeptidomics approach to identify population-wide vaccine candidates - IonOpticks
This Foster lab study into population-wide vaccine candidates by Baker et al. used IonOpticks Aurora Ultimate 25×75 CSI UHPLC columns.
bit.ly
January 13, 2026 at 12:30 AM
New globally representative vaccine screening method from the Foster lab uses 30 diverse cell lines + LC-MS/MS to identify broadly protective antigens. Analysis via EASY-nLC 1000 + timsTOF Pro with Aurora Ultimate 25x75 CSI column, identified 18 common binding motifs.
bit.ly/4qQruIe
bit.ly/4qQruIe
During his graduate studies, Mahlon Collins worked with ALS patients who underwent painful spinal taps to donate CSF for his biomarker research. Now, he leads neurodegenerative disease research at @parallelsq.bsky.social.
Learn more about Mahlon's journey: bit.ly/3NoKX4g
Learn more about Mahlon's journey: bit.ly/3NoKX4g
From patient donations to cellular insights: Mahlon Collins on single-neuron proteomics and the future of Alzheimer’s research
Mahlon Collins leads neurodegenerative disease research at the Parallel Squared Technology Institute (PTI). A neurobiologist by training, he has witnessed firsthand the tremendous burden these disease...
bit.ly
January 12, 2026 at 11:29 PM
During his graduate studies, Mahlon Collins worked with ALS patients who underwent painful spinal taps to donate CSF for his biomarker research. Now, he leads neurodegenerative disease research at @parallelsq.bsky.social.
Learn more about Mahlon's journey: bit.ly/3NoKX4g
Learn more about Mahlon's journey: bit.ly/3NoKX4g
Hwang et al. develop HLA-Shuttle, a system using engineered components of the HLA-I processing machinery to restore and stabilise HLA-I complexes on tumour cell surfaces. Immunopeptidomic samples separated on Aurora Ultimate 25x75, data acquired on nanoElute 2 + timsTOF Ultra 2.
bit.ly/49tdq0m
bit.ly/49tdq0m
HLA-Shuttle: A system for enhancing antigen presentation in immunologically cold tumors
HLA-Shuttle enhances production of HLA class I molecules in neuroblastoma, leading to the discovery of tumor-associated antigens.
bit.ly
January 8, 2026 at 11:30 PM
Hwang et al. develop HLA-Shuttle, a system using engineered components of the HLA-I processing machinery to restore and stabilise HLA-I complexes on tumour cell surfaces. Immunopeptidomic samples separated on Aurora Ultimate 25x75, data acquired on nanoElute 2 + timsTOF Ultra 2.
bit.ly/49tdq0m
bit.ly/49tdq0m
IonOpticks columns were cited over 1,000 times in 2025. That’s over 1,000 different ways in which our columns powered breakthrough research. Less than eight years ago, we were celebrating our first 10. Thank you to everyone who supported us on this journey.
Explore all publications: bit.ly/4spHNgF
Explore all publications: bit.ly/4spHNgF
January 7, 2026 at 11:36 PM
IonOpticks columns were cited over 1,000 times in 2025. That’s over 1,000 different ways in which our columns powered breakthrough research. Less than eight years ago, we were celebrating our first 10. Thank you to everyone who supported us on this journey.
Explore all publications: bit.ly/4spHNgF
Explore all publications: bit.ly/4spHNgF
New year. New budget. New possibilities.
Elevate your proteomics workflows in 2026 - whether that means complete LC-MS setup, stocked replacement columns, or adding trap column protection to extend analytical column life.
Start the year equipped: bit.ly/4preV4S
Elevate your proteomics workflows in 2026 - whether that means complete LC-MS setup, stocked replacement columns, or adding trap column protection to extend analytical column life.
Start the year equipped: bit.ly/4preV4S
January 7, 2026 at 6:33 AM
New year. New budget. New possibilities.
Elevate your proteomics workflows in 2026 - whether that means complete LC-MS setup, stocked replacement columns, or adding trap column protection to extend analytical column life.
Start the year equipped: bit.ly/4preV4S
Elevate your proteomics workflows in 2026 - whether that means complete LC-MS setup, stocked replacement columns, or adding trap column protection to extend analytical column life.
Start the year equipped: bit.ly/4preV4S
Chemla et al. reveal how melanoma evades the immune system through an unexpected mechanism: melanosomes acting as molecular decoys. LC-MS/MS used an Aurora Ultimate 25x75 CSI column with a timsTOF Ultra and nanoElute 2.
Learn more: bit.ly/4qcP426
Learn more: bit.ly/4qcP426
HLA export by melanoma cells decoys cytotoxic T cells to promote immune evasion - IonOpticks
This Levy lab study into HLA export by melanoma cells by Chemla et al. used IonOpticks Aurora Ultimate 25×75 CSI UHPLC columns.
bit.ly
January 5, 2026 at 1:50 AM
Chemla et al. reveal how melanoma evades the immune system through an unexpected mechanism: melanosomes acting as molecular decoys. LC-MS/MS used an Aurora Ultimate 25x75 CSI column with a timsTOF Ultra and nanoElute 2.
Learn more: bit.ly/4qcP426
Learn more: bit.ly/4qcP426
2025 was a remarkable year. Two themes that define it for IO are recognition and reach. Awards and industry recognition validated what our community knew for years, while our team expanded across continents, bringing us closer to the researchers and partners we serve.
2025 in review: bit.ly/3MQpEIG
2025 in review: bit.ly/3MQpEIG
2025 in review: A year of recognition, growth, new products, and more people where you need them.
IN THIS EDITION 2025 has come to an end, and, looking back, it’s clear quite quickly what a remarkable year this was for IonOpticks. It’s striking how much has changed in just 12 months.
bit.ly
December 24, 2025 at 1:38 AM
2025 was a remarkable year. Two themes that define it for IO are recognition and reach. Awards and industry recognition validated what our community knew for years, while our team expanded across continents, bringing us closer to the researchers and partners we serve.
2025 in review: bit.ly/3MQpEIG
2025 in review: bit.ly/3MQpEIG
Wrapping up an unforgettable PSI-2025. It’s not every day we're at a conference where we can barely sit - the interest in our leading chromatography solutions was truly non-stop. And where else do you get to exhibit outdoors in beautiful Hyderabad? Thank you to the organisers for a great event.
December 22, 2025 at 10:35 PM
Wrapping up an unforgettable PSI-2025. It’s not every day we're at a conference where we can barely sit - the interest in our leading chromatography solutions was truly non-stop. And where else do you get to exhibit outdoors in beautiful Hyderabad? Thank you to the organisers for a great event.
2025 was a remarkable year for IonOpticks, defined by recognition & global reach. Industry awards validated our work, while our growing team strengthened connections with researchers worldwide. We’re proud to expand our impact while staying true to our collaborative spirit. Read our year in review.
2025 in review: A year of recognition, growth, new products, and more people where you need them.
IN THIS EDITION 2025 has come to an end, and, looking back, it’s clear quite quickly what a remarkable year this was for IonOpticks. It’s striking how much has changed in just 12 months.
www.linkedin.com
December 22, 2025 at 6:43 AM
2025 was a remarkable year for IonOpticks, defined by recognition & global reach. Industry awards validated our work, while our growing team strengthened connections with researchers worldwide. We’re proud to expand our impact while staying true to our collaborative spirit. Read our year in review.
What a year it’s been - time to recharge and enjoy a well-earned break. Our office will be closed from December 25th to January 4th and we’ll be back online from Monday, January 5th.
We wish you a safe and festive holiday break. See you in 2026!
We wish you a safe and festive holiday break. See you in 2026!
December 22, 2025 at 1:06 AM
What a year it’s been - time to recharge and enjoy a well-earned break. Our office will be closed from December 25th to January 4th and we’ll be back online from Monday, January 5th.
We wish you a safe and festive holiday break. See you in 2026!
We wish you a safe and festive holiday break. See you in 2026!
The ZenoTOF 8600 paired with Aurora Series columns: a powerful combination showcased by @sciex.bsky.social’s Jean-Baptiste Vincendet at PSI-2025. >10,000 protein group IDs from 250 ng K562 cell line. Eager to see what else researchers achieve as adoption of the ZenoTOF 8600 system continues to grow.
December 22, 2025 at 12:31 AM
The ZenoTOF 8600 paired with Aurora Series columns: a powerful combination showcased by @sciex.bsky.social’s Jean-Baptiste Vincendet at PSI-2025. >10,000 protein group IDs from 250 ng K562 cell line. Eager to see what else researchers achieve as adoption of the ZenoTOF 8600 system continues to grow.
12-lab study shows that DIA methods ID 1.8× more proteins than traditional DDA approaches in plasma analysis, with significantly better reproducibility (5.9% vs 15.4% CV). Distler et al.'s standardised approach brings clinical proteomics closer to accredited diagnostics.
bit.ly/492ZhXk
bit.ly/492ZhXk
Multicenter evaluation of label-free quantification in human plasma on a high dynamic range benchmark set - IonOpticks
This human plasma benchmark set study by Distler et al. used IonOpticks Aurora Ultimate 25×75 CSI and Aurora Rapid 5x150 CSI UHPLC columns.
bit.ly
December 21, 2025 at 10:32 PM
12-lab study shows that DIA methods ID 1.8× more proteins than traditional DDA approaches in plasma analysis, with significantly better reproducibility (5.9% vs 15.4% CV). Distler et al.'s standardised approach brings clinical proteomics closer to accredited diagnostics.
bit.ly/492ZhXk
bit.ly/492ZhXk
We’re proud to be supporting the 17th Annual Meeting of the Proteomics Society, India at the CSIR-CCMB in Hyderabad this week. Fabrice and Erik will be behind the IonOpticks booth from December 18-20 to chat about all things chromatography and how we can support your proteomics workflows.
December 16, 2025 at 11:33 PM
We’re proud to be supporting the 17th Annual Meeting of the Proteomics Society, India at the CSIR-CCMB in Hyderabad this week. Fabrice and Erik will be behind the IonOpticks booth from December 18-20 to chat about all things chromatography and how we can support your proteomics workflows.
TWO WEEKS LEFT: Say yes to every sample with a complimentary 3-pack of NEW NanoShield™ reversed-flush C18 trap columns with every HeatSync™ Starter Pack, and Aurora Series® 5 and 10-pack through December!
Shop online or request a quote: bit.ly/4pPMP44
Promotion ends 11:59pm AEDT December 31, 2025
Shop online or request a quote: bit.ly/4pPMP44
Promotion ends 11:59pm AEDT December 31, 2025
December 12, 2025 at 2:41 AM
TWO WEEKS LEFT: Say yes to every sample with a complimentary 3-pack of NEW NanoShield™ reversed-flush C18 trap columns with every HeatSync™ Starter Pack, and Aurora Series® 5 and 10-pack through December!
Shop online or request a quote: bit.ly/4pPMP44
Promotion ends 11:59pm AEDT December 31, 2025
Shop online or request a quote: bit.ly/4pPMP44
Promotion ends 11:59pm AEDT December 31, 2025
Zhang et al. develop SPIDR (Single-cell Protein Immobilisation and Digestion tube Reactor), an accessible, high-throughput approach that simplifies single-cell proteomics for resource-limited labs. LC-MS/MS used Aurora Ultimate 25x75 CSI column on nanoElute coupled to timsTOF Pro 2.
bit.ly/44iDR7e
bit.ly/44iDR7e
A Simple and Flexible Strategy for Single-Cell Proteomic Analysis Based on Protein Immobilization and Digestion Tube Reactor
Mass spectrometry-based single-cell proteomics (SCP) analysis has witnessed rapid development over the past 10 years. However, the current preprocessing methodologies face several challenges: multiple...
bit.ly
December 11, 2025 at 10:43 PM
Zhang et al. develop SPIDR (Single-cell Protein Immobilisation and Digestion tube Reactor), an accessible, high-throughput approach that simplifies single-cell proteomics for resource-limited labs. LC-MS/MS used Aurora Ultimate 25x75 CSI column on nanoElute coupled to timsTOF Pro 2.
bit.ly/44iDR7e
bit.ly/44iDR7e
Please welcome Haley Oller as Field Application Specialist - North America. With over a decade of experience in MS and proteomics, Haley brings technical expertise and a passion for collaborative science. She's excited to support proteomic scientists and help facilitate the next wave of discoveries.
December 11, 2025 at 10:08 PM
Please welcome Haley Oller as Field Application Specialist - North America. With over a decade of experience in MS and proteomics, Haley brings technical expertise and a passion for collaborative science. She's excited to support proteomic scientists and help facilitate the next wave of discoveries.
Anyone who’s been to our User Appreciation Events knows how important events are to us, which is why we're thrilled to welcome Annie Ward as our Global Events Manager. Our User Event in Toronto was all Annie - we can’t wait to see how she shapes our upcoming events into unforgettable experiences.
December 8, 2025 at 11:29 PM
Anyone who’s been to our User Appreciation Events knows how important events are to us, which is why we're thrilled to welcome Annie Ward as our Global Events Manager. Our User Event in Toronto was all Annie - we can’t wait to see how she shapes our upcoming events into unforgettable experiences.
NOW PUBLISHED: An open-source framework, alphaDIA, uses a feature-free approach to process complex spectral data, outperforming existing methods across various platforms.
Samples separated on Aurora Elite 15x75 by Whisper 40SPD method & on Aurora Rapid 8x150 by Whisper 60SPD.
bit.ly/48Go0R9
Samples separated on Aurora Elite 15x75 by Whisper 40SPD method & on Aurora Rapid 8x150 by Whisper 60SPD.
bit.ly/48Go0R9
AlphaDIA enables DIA transfer learning for feature-free proteomics - IonOpticks
This feature-free proteomics study by Wallmann et al. used IonOpticks Aurora Elite 15×75 and Aurora Rapid 8x150 XT UHPLC columns.
bit.ly
December 8, 2025 at 2:20 AM
NOW PUBLISHED: An open-source framework, alphaDIA, uses a feature-free approach to process complex spectral data, outperforming existing methods across various platforms.
Samples separated on Aurora Elite 15x75 by Whisper 40SPD method & on Aurora Rapid 8x150 by Whisper 60SPD.
bit.ly/48Go0R9
Samples separated on Aurora Elite 15x75 by Whisper 40SPD method & on Aurora Rapid 8x150 by Whisper 60SPD.
bit.ly/48Go0R9
Callahan et al. suggest the kinase Itk as a potential target for reducing unwanted CAR activity. Phosphotyrosine-enriched peptides separated with Vanquish Neo & Aurora Ultimate 25x75 column. MS performed on an Orbitrap Ascend.
bit.ly/3Mn9Ugc
bit.ly/3Mn9Ugc
Phosphoproteomic analysis of successive Jurkat CD19-CAR generations reveals TCRζ-driven signalling
Although chimeric antigen receptor (CAR) T cell therapy has revolutionised individualised cancer therapies for relapsed/refractory lymphomas, low long…
bit.ly
December 7, 2025 at 10:45 PM
Callahan et al. suggest the kinase Itk as a potential target for reducing unwanted CAR activity. Phosphotyrosine-enriched peptides separated with Vanquish Neo & Aurora Ultimate 25x75 column. MS performed on an Orbitrap Ascend.
bit.ly/3Mn9Ugc
bit.ly/3Mn9Ugc
Get a complimentary 3-pack of NEW NanoShield™ trap columns with every Aurora Series starter pack, 5-pack, or 10-pack. Run every sample confidently, knowing your analytical columns are safeguarded. Start 2026 fully stocked AND protected.
Stock up before December 31, 11:59pm AEST: bit.ly/4pPMP44
Stock up before December 31, 11:59pm AEST: bit.ly/4pPMP44
December 5, 2025 at 5:50 AM
Get a complimentary 3-pack of NEW NanoShield™ trap columns with every Aurora Series starter pack, 5-pack, or 10-pack. Run every sample confidently, knowing your analytical columns are safeguarded. Start 2026 fully stocked AND protected.
Stock up before December 31, 11:59pm AEST: bit.ly/4pPMP44
Stock up before December 31, 11:59pm AEST: bit.ly/4pPMP44
It’s been a great start to ITPA 2025 - talking to local customers, getting to know the Italian proteomics community, and the challenges they're facing. Stop by our exhibition booth and chat to Britta to learn more, share your challenges, and explore NanoShield™ with a dedicated new application note.
December 5, 2025 at 4:33 AM
It’s been a great start to ITPA 2025 - talking to local customers, getting to know the Italian proteomics community, and the challenges they're facing. Stop by our exhibition booth and chat to Britta to learn more, share your challenges, and explore NanoShield™ with a dedicated new application note.