ISSLS
@issls.bsky.social
The International Society for the Study of Lumbar Spine (ISSLS) brings together individuals from across the globe for the purpose of research and clinical study into the lumbar spine.
Reposted by ISSLS
Does every patient with lumbar spinal stenosis and high-signal facet joints need spinal fusion? 🧵
Our new study says no, not always! A simpler approach might be the way forward for some patients in the Hunter New England Local Health District.
www.doi.org/10.1007/s005...
Our new study says no, not always! A simpler approach might be the way forward for some patients in the Hunter New England Local Health District.
www.doi.org/10.1007/s005...
Comparable long-term pain and disability outcomes following decompression alone versus decompression with fusion in lumbar spinal stenosis patients with high-signal facet joints - European Spine Journ...
Purpose This study aimed to evaluate the long-term outcomes of decompressive surgery with or without fusion in patients with lumbar spinal stenosis (LSS) exhibiting high-signal facet joints, a radiolo...
www.doi.org
June 30, 2025 at 2:09 AM
Does every patient with lumbar spinal stenosis and high-signal facet joints need spinal fusion? 🧵
Our new study says no, not always! A simpler approach might be the way forward for some patients in the Hunter New England Local Health District.
www.doi.org/10.1007/s005...
Our new study says no, not always! A simpler approach might be the way forward for some patients in the Hunter New England Local Health District.
www.doi.org/10.1007/s005...
📣 One week left to submit your abstract ‼️
The abstract deadline for the combined #ISSLS & #SASS 2026 Annual Meeting in Cape Town, South Africa (May 11–15, 2026) has been extended until November 15, 2025 ‼️
issls2026.org/abstracts/
#ISSLS2026 #CapeTown #SpineResearch
The abstract deadline for the combined #ISSLS & #SASS 2026 Annual Meeting in Cape Town, South Africa (May 11–15, 2026) has been extended until November 15, 2025 ‼️
issls2026.org/abstracts/
#ISSLS2026 #CapeTown #SpineResearch
Abstracts - ISSLS/SASS Annual Meeting 2026
issls2026.org
November 7, 2025 at 9:36 AM
📣 One week left to submit your abstract ‼️
The abstract deadline for the combined #ISSLS & #SASS 2026 Annual Meeting in Cape Town, South Africa (May 11–15, 2026) has been extended until November 15, 2025 ‼️
issls2026.org/abstracts/
#ISSLS2026 #CapeTown #SpineResearch
The abstract deadline for the combined #ISSLS & #SASS 2026 Annual Meeting in Cape Town, South Africa (May 11–15, 2026) has been extended until November 15, 2025 ‼️
issls2026.org/abstracts/
#ISSLS2026 #CapeTown #SpineResearch
ISSLS membership applications are now open until the 19th of September!
Join our global community of world-class spine researchers, clinicians, surgeons, and more before the deadline closes
📅 Deadline to apply: September 19th
🔗 Learn more and apply: www.issls.org/membership
Why join ISSLS? 👇🏼
Join our global community of world-class spine researchers, clinicians, surgeons, and more before the deadline closes
📅 Deadline to apply: September 19th
🔗 Learn more and apply: www.issls.org/membership
Why join ISSLS? 👇🏼
MEMBERSHIP APPLICATION — The International Society for the Study of the Lumbar Spine
www.issls.org
September 9, 2025 at 10:39 AM
ISSLS membership applications are now open until the 19th of September!
Join our global community of world-class spine researchers, clinicians, surgeons, and more before the deadline closes
📅 Deadline to apply: September 19th
🔗 Learn more and apply: www.issls.org/membership
Why join ISSLS? 👇🏼
Join our global community of world-class spine researchers, clinicians, surgeons, and more before the deadline closes
📅 Deadline to apply: September 19th
🔗 Learn more and apply: www.issls.org/membership
Why join ISSLS? 👇🏼
🌟 Welcome Dr. Tamara Mengis – Our Newest ISSLS Member! 🌟
We’re excited to welcome Dr. Tamara Mengis, PhD to the #ISSLS community of spine researchers and clinicians!
We’re excited to welcome Dr. Tamara Mengis, PhD to the #ISSLS community of spine researchers and clinicians!
July 21, 2025 at 12:17 PM
🌟 Welcome Dr. Tamara Mengis – Our Newest ISSLS Member! 🌟
We’re excited to welcome Dr. Tamara Mengis, PhD to the #ISSLS community of spine researchers and clinicians!
We’re excited to welcome Dr. Tamara Mengis, PhD to the #ISSLS community of spine researchers and clinicians!
🎉 Congratulations to the 2025 ISSLS Best Paper Award Winner! 🎉
We are thrilled to spotlight some of the most compelling research in #LumbarSpine science and clinical innovation.
This year’s Best Paper Award was to Prof. Gianluca Vadalà et al of the Università Campus Bio-Medico di Roma
We are thrilled to spotlight some of the most compelling research in #LumbarSpine science and clinical innovation.
This year’s Best Paper Award was to Prof. Gianluca Vadalà et al of the Università Campus Bio-Medico di Roma
July 21, 2025 at 12:13 PM
🎉 Congratulations to the 2025 ISSLS Best Paper Award Winner! 🎉
We are thrilled to spotlight some of the most compelling research in #LumbarSpine science and clinical innovation.
This year’s Best Paper Award was to Prof. Gianluca Vadalà et al of the Università Campus Bio-Medico di Roma
We are thrilled to spotlight some of the most compelling research in #LumbarSpine science and clinical innovation.
This year’s Best Paper Award was to Prof. Gianluca Vadalà et al of the Università Campus Bio-Medico di Roma
In Memoriam of Dr. Margareta Nordin (1945–2025)
Please read the beautiful obituary by Dino Samartzis and Björn Rydevik in the #EuropeanSpineJournal here: 🔗 link.springer.com/article/10.1...
Please read the beautiful obituary by Dino Samartzis and Björn Rydevik in the #EuropeanSpineJournal here: 🔗 link.springer.com/article/10.1...
July 9, 2025 at 6:53 AM
In Memoriam of Dr. Margareta Nordin (1945–2025)
Please read the beautiful obituary by Dino Samartzis and Björn Rydevik in the #EuropeanSpineJournal here: 🔗 link.springer.com/article/10.1...
Please read the beautiful obituary by Dino Samartzis and Björn Rydevik in the #EuropeanSpineJournal here: 🔗 link.springer.com/article/10.1...
We’re already halfway through ISSLS 2025! 😲
From cutting-edge research to truly inspiring discussions, the energy here is amazing. #ISSLS2025
From cutting-edge research to truly inspiring discussions, the energy here is amazing. #ISSLS2025
May 15, 2025 at 3:56 PM
We’re already halfway through ISSLS 2025! 😲
From cutting-edge research to truly inspiring discussions, the energy here is amazing. #ISSLS2025
From cutting-edge research to truly inspiring discussions, the energy here is amazing. #ISSLS2025
Great special poster session this morning #ISSLS2025 on #IVD degeneration chaired by Stefan Dudli and Kotaro Nishida
May 14, 2025 at 1:28 PM
Great special poster session this morning #ISSLS2025 on #IVD degeneration chaired by Stefan Dudli and Kotaro Nishida
Presenters are getting robust and constructive questioning here very much in the spirit of #ISSLS2025! Halfway through a great session here including studies on #Modicchanges and deep learning spine variables extracted from UK biobank
May 13, 2025 at 6:28 PM
Presenters are getting robust and constructive questioning here very much in the spirit of #ISSLS2025! Halfway through a great session here including studies on #Modicchanges and deep learning spine variables extracted from UK biobank
#ISSLS2025 has officially kicked off here in Atlanta with the basic science session!
May 13, 2025 at 12:05 PM
#ISSLS2025 has officially kicked off here in Atlanta with the basic science session!
Preoperative #SleepDisturbances and #Depression independently and jointly predict higher disability and pain 12 months after lumbar #SpineSurgery.
The latest publication in Spine by #ISSLS member Kristin R. Archer and team: journals.lww.com/spinejournal...
The latest publication in Spine by #ISSLS member Kristin R. Archer and team: journals.lww.com/spinejournal...
The Combined Influence of Sleep Disturbance and Depression... : Spine
havioral factors are considered major risk factors for poor outcomes after LSS. However, there is a need to explore the combined effects of preoperative factors such as sleep disturbance and depressio...
journals.lww.com
April 10, 2025 at 6:49 AM
Preoperative #SleepDisturbances and #Depression independently and jointly predict higher disability and pain 12 months after lumbar #SpineSurgery.
The latest publication in Spine by #ISSLS member Kristin R. Archer and team: journals.lww.com/spinejournal...
The latest publication in Spine by #ISSLS member Kristin R. Archer and team: journals.lww.com/spinejournal...
The latest publication in The Spine Journal by Todd Alamin investigates patient acceptance of reoperation risk following lumbar decompression and fusion surgeries, revealing some important findings that could impact the future of #LumbarSpine research.
www.thespinejournalonline.com/article/S152...
www.thespinejournalonline.com/article/S152...
Patient acceptance of reoperation risk for lumbar decompression versus fusion
Lumbar decompression and lumbar fusion are effective methods of treating spinal compressive
pathologies refractory to conservative management. These surgeries are typically used
to treat different spi...
www.thespinejournalonline.com
April 10, 2025 at 6:46 AM
The latest publication in The Spine Journal by Todd Alamin investigates patient acceptance of reoperation risk following lumbar decompression and fusion surgeries, revealing some important findings that could impact the future of #LumbarSpine research.
www.thespinejournalonline.com/article/S152...
www.thespinejournalonline.com/article/S152...
🌟 Introducing Dr. Shota Tamagawa – Our Newest ISSLS Member! 🌟
ISSLS is thrilled to welcome Shota Tamagawa, MD, PhD, Assistant Professor at Juntendo University Faculty of Medicine, Tokyo, Japan, to our #ISSLS community of spine researchers and clinicians!
ISSLS is thrilled to welcome Shota Tamagawa, MD, PhD, Assistant Professor at Juntendo University Faculty of Medicine, Tokyo, Japan, to our #ISSLS community of spine researchers and clinicians!
April 10, 2025 at 6:44 AM
🌟 Introducing Dr. Shota Tamagawa – Our Newest ISSLS Member! 🌟
ISSLS is thrilled to welcome Shota Tamagawa, MD, PhD, Assistant Professor at Juntendo University Faculty of Medicine, Tokyo, Japan, to our #ISSLS community of spine researchers and clinicians!
ISSLS is thrilled to welcome Shota Tamagawa, MD, PhD, Assistant Professor at Juntendo University Faculty of Medicine, Tokyo, Japan, to our #ISSLS community of spine researchers and clinicians!
🌟 Welcome Dr. Jacopo Vitale – Our Newest ISSLS Member! 🌟
Dr. Vitale is a Research Associate at the Spine Centre at Schulthess Klinik in Zürich (Switzerland) and Associate Professor at the Institute of Sports Sciences at University of Physical Culture in Cracow (Poland).
Dr. Vitale is a Research Associate at the Spine Centre at Schulthess Klinik in Zürich (Switzerland) and Associate Professor at the Institute of Sports Sciences at University of Physical Culture in Cracow (Poland).
April 10, 2025 at 6:40 AM
🌟 Welcome Dr. Jacopo Vitale – Our Newest ISSLS Member! 🌟
Dr. Vitale is a Research Associate at the Spine Centre at Schulthess Klinik in Zürich (Switzerland) and Associate Professor at the Institute of Sports Sciences at University of Physical Culture in Cracow (Poland).
Dr. Vitale is a Research Associate at the Spine Centre at Schulthess Klinik in Zürich (Switzerland) and Associate Professor at the Institute of Sports Sciences at University of Physical Culture in Cracow (Poland).
Publication in #ScienceAdvances by #ISSLS member Prof. Lisbet Haglund: www.science.org/doi/full/10.... This study investigates the potential of two senolytic drugs in treating #LowBackPain by targeting senescent cells, which accumulate with aging and contribute to #inflammation and degeneration
Senolytic treatment for low back pain
Senolytics drugs can reduce back pain by removing senescent cells from the intervertebral discs and spinal cord.
www.science.org
April 10, 2025 at 6:33 AM
Publication in #ScienceAdvances by #ISSLS member Prof. Lisbet Haglund: www.science.org/doi/full/10.... This study investigates the potential of two senolytic drugs in treating #LowBackPain by targeting senescent cells, which accumulate with aging and contribute to #inflammation and degeneration
📢 Publication in FASEB J by #ISSLS member Dr. Lachlan Smith et al highlights key findings using single cell RNA seq., revealing the diversity & crucial roles of notochord-derived NP cells in the postnatal mouse disc #SpineResearch #LumbarSpine #LowBackPain #RegenerativeMedicine #Biotechnology Link 👇🏼
March 19, 2025 at 12:15 PM
📢 Publication in FASEB J by #ISSLS member Dr. Lachlan Smith et al highlights key findings using single cell RNA seq., revealing the diversity & crucial roles of notochord-derived NP cells in the postnatal mouse disc #SpineResearch #LumbarSpine #LowBackPain #RegenerativeMedicine #Biotechnology Link 👇🏼
The #ISSLS Phenotype/Precision Spine Focus Group is driving advancements in low back pain management through predictive biomarkers. Their 2024 recommendations, now published in the European Spine Journal, emphasize unified terminology, robust research designs, and overcoming development barriers 👇🏼
Development and application of predictive clinical biomarkers for low back pain care: recommendations from the ISSLS phenotype/precision spine focus group - European Spine Journal
Predictive biomarkers (or moderators of treatment) are features, or more likely feature clusters, that discriminate individuals who are more likely to experience a favourable or unfavourable effect fr...
link.springer.com
March 11, 2025 at 12:26 PM
The #ISSLS Phenotype/Precision Spine Focus Group is driving advancements in low back pain management through predictive biomarkers. Their 2024 recommendations, now published in the European Spine Journal, emphasize unified terminology, robust research designs, and overcoming development barriers 👇🏼
📢 New study by #ISSLS member Dr. Kakutani reveals TRPV4 knockdown impairs ECM synthesis via autophagy suppression, leading to disc degeneration in rats. Underscores autophagy's role in disc health, suggesting TRPV4 as a target for new therapies #SpineResearch onlinelibrary.wiley.com/doi/10.1002/...
Transient Receptor Potential Vanilloid 4 Knockdown Decreases Extracellular Matrix Synthesis via Autophagy Suppression in the Rat Intervertebral Disc
We conducted in vitro and in vivo TRPV4 RNA interference study in the rat intervertebral disc cells and tissues. In vitro, TRPV4 knockdown decreased extracellular matrix synthesis, cell viability, an...
onlinelibrary.wiley.com
March 11, 2025 at 12:10 PM
📢 New study by #ISSLS member Dr. Kakutani reveals TRPV4 knockdown impairs ECM synthesis via autophagy suppression, leading to disc degeneration in rats. Underscores autophagy's role in disc health, suggesting TRPV4 as a target for new therapies #SpineResearch onlinelibrary.wiley.com/doi/10.1002/...
🚨 Perioperative spinal cord injury in high-risk adult deformity surgery is rare but devastating. The latest study in Spinal Cord Series & Cases by #ISSLS members Fan Jiang & colleagues examines its incidence, causes, outcomes, and management strategies. 🧠🔍 Full paper: www.nature.com/articles/s41...
Spinal cord injury in high-risk complex adult spinal deformity surgery: review of incidence and outcomes from the Scoli-RISK-1 study - Spinal Cord Series and Cases
Spinal Cord Series and Cases - Spinal cord injury in high-risk complex adult spinal deformity surgery: review of incidence and outcomes from the Scoli-RISK-1 study
www.nature.com
March 11, 2025 at 12:05 PM
🚨 Perioperative spinal cord injury in high-risk adult deformity surgery is rare but devastating. The latest study in Spinal Cord Series & Cases by #ISSLS members Fan Jiang & colleagues examines its incidence, causes, outcomes, and management strategies. 🧠🔍 Full paper: www.nature.com/articles/s41...
📢 Check out the work of #ISSLS member Svenja Illien-Junger et al. in #JORSpine on PHLPP1’s role in IVD degeneration & small molecule inhibitors. Full study 👉 onlinelibrary.wiley.com/doi/10.1002/...
#SpineResearch
#SpineResearch
Differential efficacy of two small molecule PHLPP inhibitors to promote nucleus Pulposus cell health
Pharmacological inhibition of PHLPP via NSC45586 promotes nucleus pulposus cell health. NSC45586 is a potential drug candidate in treating IVD degeneration.
onlinelibrary.wiley.com
March 6, 2025 at 7:56 AM
📢 Check out the work of #ISSLS member Svenja Illien-Junger et al. in #JORSpine on PHLPP1’s role in IVD degeneration & small molecule inhibitors. Full study 👉 onlinelibrary.wiley.com/doi/10.1002/...
#SpineResearch
#SpineResearch
📢 Get ready for #ISSLS2025, abstract decisions have been out for a few weeks now! We can't wait for an exciting meeting in Atlanta this May, where groundbreaking #SpineResearch takes centre stage. Check out the programme and speakers: www.isslsmeetings.org/2025-program
March 5, 2025 at 3:04 PM
📢 Get ready for #ISSLS2025, abstract decisions have been out for a few weeks now! We can't wait for an exciting meeting in Atlanta this May, where groundbreaking #SpineResearch takes centre stage. Check out the programme and speakers: www.isslsmeetings.org/2025-program
Reposted by ISSLS
Your curriculum vitae (CV) is essential for showcasing your accomplishments as a scientist, leader, and colleague. Join this #WebinarWednesday on March 12 to learn key tips for crafting an effective CV for academia and industry. Register now: bit.ly/4b5XIYl
February 19, 2025 at 5:15 PM
Your curriculum vitae (CV) is essential for showcasing your accomplishments as a scientist, leader, and colleague. Join this #WebinarWednesday on March 12 to learn key tips for crafting an effective CV for academia and industry. Register now: bit.ly/4b5XIYl
Today is the last change to apply for a travel grant to ISSLS
Eligibility 🎯:
🔹 First-time ISSLS in-person attendee
🔹 First/presenting author on an accepted abstract
🔹 Graduate student or within 4 years post-qualification (or under 40 as an independent researcher)
www.isslsmeetings.org/travel-grant
Eligibility 🎯:
🔹 First-time ISSLS in-person attendee
🔹 First/presenting author on an accepted abstract
🔹 Graduate student or within 4 years post-qualification (or under 40 as an independent researcher)
www.isslsmeetings.org/travel-grant
February 14, 2025 at 10:48 AM
Today is the last change to apply for a travel grant to ISSLS
Eligibility 🎯:
🔹 First-time ISSLS in-person attendee
🔹 First/presenting author on an accepted abstract
🔹 Graduate student or within 4 years post-qualification (or under 40 as an independent researcher)
www.isslsmeetings.org/travel-grant
Eligibility 🎯:
🔹 First-time ISSLS in-person attendee
🔹 First/presenting author on an accepted abstract
🔹 Graduate student or within 4 years post-qualification (or under 40 as an independent researcher)
www.isslsmeetings.org/travel-grant
Jacopo A Vitale et al. in the journal Brain and Spine have shown a significant correlation between epimuscular fat and #LowBackPain intensity.
🔗 doi: doi.org/10.1016/j.ba...
🔗 doi: doi.org/10.1016/j.ba...
January 28, 2025 at 11:49 AM
Jacopo A Vitale et al. in the journal Brain and Spine have shown a significant correlation between epimuscular fat and #LowBackPain intensity.
🔗 doi: doi.org/10.1016/j.ba...
🔗 doi: doi.org/10.1016/j.ba...