Jakub Kopal
@jakubkopal.bsky.social
#MSCActions postdoctoral fellow at University of Oslo
Pinned
Jakub Kopal
@jakubkopal.bsky.social
· Jul 22
Out now in #natBME: We explore how rare high-effect gene-coding variants (#CNVs) shape brain architecture and influence cognitive and socio-behavioral traits in adolescents (#ABCD).
nature.com/articles/s41...
nature.com/articles/s41...
Out now in #natBME: We explore how rare high-effect gene-coding variants (#CNVs) shape brain architecture and influence cognitive and socio-behavioral traits in adolescents (#ABCD).
nature.com/articles/s41...
nature.com/articles/s41...
July 22, 2025 at 9:22 AM
Out now in #natBME: We explore how rare high-effect gene-coding variants (#CNVs) shape brain architecture and influence cognitive and socio-behavioral traits in adolescents (#ABCD).
nature.com/articles/s41...
nature.com/articles/s41...
#Multimorbidity is a pressing challenge in health care.
We dissect its genetic architecture across mental and physical health, revealing shared and distinct links between brain structure, psychiatric disorders, and cardiometabolic disease.
www.medrxiv.org/content/10.1...
We dissect its genetic architecture across mental and physical health, revealing shared and distinct links between brain structure, psychiatric disorders, and cardiometabolic disease.
www.medrxiv.org/content/10.1...
May 23, 2025 at 6:09 AM
#Multimorbidity is a pressing challenge in health care.
We dissect its genetic architecture across mental and physical health, revealing shared and distinct links between brain structure, psychiatric disorders, and cardiometabolic disease.
www.medrxiv.org/content/10.1...
We dissect its genetic architecture across mental and physical health, revealing shared and distinct links between brain structure, psychiatric disorders, and cardiometabolic disease.
www.medrxiv.org/content/10.1...
Reposted by Jakub Kopal
Introducing FEMA-Long for high-dimensional large-scale mixed-effects modelling! Includes modelling unstructured covariance, non-linear effects using splines, time-dependent effects with spline interactions, and longitudinal GWAS with time-dependent genetic effects!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
FEMA-Long: Modeling unstructured covariances for discovery of time-dependent effects in large-scale longitudinal datasets
Linear mixed-effects (LME) models are commonly used for analyzing longitudinal data. However, most applications of LME models rely on random intercepts or simple, e.g., stationary, covariance. Here, w...
www.biorxiv.org
May 16, 2025 at 3:22 PM
Introducing FEMA-Long for high-dimensional large-scale mixed-effects modelling! Includes modelling unstructured covariance, non-linear effects using splines, time-dependent effects with spline interactions, and longitudinal GWAS with time-dependent genetic effects!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Understanding #Parkinsons subtypes is key to more targeted RCTs & better therapeutics! 🧠 Our new study finds that LRRK2 PD patients show milder cortical atrophy, with preserved temporal & occipital regions compared to sporadic PD. #LRRK2 #dataviz
www.medrxiv.org/content/10.1...
www.medrxiv.org/content/10.1...
March 12, 2025 at 1:57 PM
Understanding #Parkinsons subtypes is key to more targeted RCTs & better therapeutics! 🧠 Our new study finds that LRRK2 PD patients show milder cortical atrophy, with preserved temporal & occipital regions compared to sporadic PD. #LRRK2 #dataviz
www.medrxiv.org/content/10.1...
www.medrxiv.org/content/10.1...
Reposted by Jakub Kopal
Want to get out of Dodge? Do a postdoc @uio.no! You will be using the MoBa study and registers to study intergenerational transmission and GxE for #MentalHealth and #education using @behaviorgenetic.bsky.social and @pgcgenetics.bsky.social approaches. Please share!
www.jobbnorge.no/en/available...
www.jobbnorge.no/en/available...
Postdoctoral Fellowship in Mental Health Research (272560) | University of Oslo
Job title: Postdoctoral Fellowship in Mental Health Research (272560), Employer: University of Oslo, Deadline: Monday, February 24, 2025
www.jobbnorge.no
January 14, 2025 at 11:33 AM
Want to get out of Dodge? Do a postdoc @uio.no! You will be using the MoBa study and registers to study intergenerational transmission and GxE for #MentalHealth and #education using @behaviorgenetic.bsky.social and @pgcgenetics.bsky.social approaches. Please share!
www.jobbnorge.no/en/available...
www.jobbnorge.no/en/available...