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JAMA @jama.com · 12h

Will 2026 be the year of real-world evidence that #AI can actually improve patient care?

JAMA+ AI EIC Roy Perlis, MD, MSc, and Associate Editor Yulin Hswen, ScD, MPH, discuss in this special episode marking 1 year since the launch of JAMA+ AI:

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JAMA+ AI article "What Will Next Year Bring for AI in Health?" by Roy Perlis. Published online October 9, 2025. Features headshots of JAMA+ AI Editors Yulin Hswen and Roy Perlis.

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JAMA @jama.com · 14h

Emergency Medicaid accounts for less than 1% of total #Medicaid spending, even in states with large undocumented populations.

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A JAMA "Research Letter" published online October 9, 2025, shows a US map depicting 'Emergency Medicaid Spending for Undocumented Immigrants.' States are color-coded to show the percentage of spending, ranging from 1 to 2%.

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JAMA @jama.com · 14h

Editorial: Postoperative AF after cardiac surgery is often transient, with rare recurrence beyond 30 days, differing in pattern and risk from nonsurgical AF.

#EACTS2025

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A page from JAMA, dated October 9, 2025, titled "Is There Really Something Different About Postoperative Atrial Fibrillation After Cardiac Surgery?" by Gregory M. Marcus, MD, MAS.

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JAMA @jama.com · 14h

Among patients with insertable cardiac monitors after CABG, the cumulative 1-year incidence of new-onset AF was 48%, yet median AF burden after 30 days was nearly zero.

#EACTS2025 @eacts.bsky.social

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JAMA | Original Investigation: "Long-Term Continuous Monitoring of New-Onset Atrial Fibrillation After Coronary Artery Bypass Grafting." Includes graphs of cumulative incidence and atrial fibrillation burden post-surgery.

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JAMA @jama.com · 16h

The US Food and Drug Administration accelerated approval pathway spans many nononcologic diseases, especially nonmalignant hematology and neurology, with 25% for infectious disease vaccines.

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A research letter from JAMA, published on October 7, 2025, titled "Regulatory and Clinical Outcomes of Nononcology Accelerated Approvals." It includes Table 1 showing characteristics of approvals from 2013-2024, listing disease areas and FDA designations.

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JAMA @jama.com · 17h

Approximately 2.6 million people in the US used methamphetamine in 2023.

This JAMA Insights discusses the health consequences of methamphetamine use and recommends comprehensive care strategies.

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A page from JAMA titled 'Methamphetamine Use Disorder.' It details the drug's effects, use statistics, medical and behavioral treatments, and risks, mentioning harm reduction programs and the ASAM/AAAP guidelines.

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JAMA @jama.com · 1d

For patients with hypothermic cardiac arrest, ECLS is associated with increased survival and favorable neurological outcomes compared with other causes of cardiac arrest.

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A JAMA article titled "Extracorporeal Life Support in Accidental Hypothermia" by Konrad Mendrala, MD, PhD; Paweł Podsiadło, MD, PhD; Tomasz Darocha, MD, PhD, published online October 8, 2025. The article discusses accidental hypothermia and its treatment.

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JAMA @jama.com · 1d

Among US hospitals, fewer annual cases are now needed to reach benchmark mortality for complex cancer surgery, challenging current Leapfrog Group minimum case volume recommendations.

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JAMA research letter: "Revisiting Minimum Case Volume Recommendations for Complex Surgery in Contemporary Practice". Figure 2 shows adjusted 30-day mortality for esophagus, stomach, liver and lung surgeries from 2005-2019.

JAMA @jama.com · 1d

Editorial: Field trial supports artificial air pocket devices for delaying hypoxemia and increasing survival in simulated avalanche burial.

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An editorial from JAMA, published online October 8, 2025, titled "A Breath of Fresh Air—Improving Survival After Avalanche Burial" by Daniel S. Martin, MBChB, PhD; Helen T. McKenna, MBBS, PhD.

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JAMA @jama.com · 1d

A randomized trial of simulated snow burial demonstrated that among healthy adults, a user-carried safety device delayed hypoxemia and hypercapnia, with the goal of increasing avalanche survival rates.

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JAMA study: Does a novel device delay hypoxemia during avalanche burial? A user-carried avalanche safety device delivers airflow, delaying hypoxemia. Findings: Safety device = 35 mins, 0 terminations; Control = 6.4 mins, 7 terminations.

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JAMA @jama.com · 1d

Diverticulitis results in approximately 200 000 hospitalizations annually in the US, with an estimated health care expenditure of more than $6.3 billion annually. This Review summarizes the pathogenesis, diagnosis, and treatment of diverticulitis.

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Diagram titled: "Figure 1. Pathophysiology, Progression, and Complications of Acute Diverticulitis", contrasting uncomplicated and complicated diverticulitis with labelled anatomical drawings and related clinical information.

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JAMA @jama.com · 2d

📌 Editor’s Choice from this week's issue of #JAMA:

➡️ Comparing MRI Techniques for Prostate Cancer Diagnosis
➡️ Diverticulitis Review
➡️ H pylori Screening After Acute MI; and more.

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JAMA (Journal of the American Medical Association) cover for October 7, 2025. It lists research articles, opinion pieces, clinical reviews, and humanities articles. Featured topics include pregnancy complications, FDA approvals, and rural health care.

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JAMA @jama.com · 2d

Editorial: The PRIME trial establishes biparametric MRI as a viable alternative to multiparametric MRI for prostate cancer diagnosis, offering reduced time, cost, and invasiveness.

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A JAMA editorial from September 10, 2025, titled: "Biparametric Prostate MRI Is Safe and Effective if Image Quality Is Excellent" by Matthew S. Davenport, MD, MBA; Benjamin M. Pockros, MD, MBA; Todd M. Morgan, MD.

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JAMA @jama.com · 2d

In a trial of men with suspected #ProstateCancer, biparametric MRI, which excludes the gadolinium contrast sequence, was noninferior to multiparametric MRI for detecting clinically significant cases.

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A table compares test performance of biparametric and multiparametric MRI for prostate cancer diagnosis. Sensitivity, specificity, PPV and NPV are listed with percentages and confidence intervals.

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JAMA @jama.com · 2d

Among patients with acute myocardial infarction, routine screening for Helicobacter pylori did not significantly reduce upper gastrointestinal bleeding.

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Infographic on H. pylori screening: 13,138 men, 5,328 women (adult Swedish residents) with myocardial infarction studied. Intervention: 19,407 patients randomized, some screened for H. pylori. Findings: No significant difference in gastrointestinal bleeding.

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JAMA @jama.com · 2d

Editorial: Although myo-inositol supplementation did not improve pregnancy outcomes in individuals with PCOS, effective prevention requires understanding complex mechanisms and greater inclusion of pregnant populations in clinical trials.

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A JAMA editorial published September 8, 2025, titled "Myo-inositol to Prevent Pregnancy Complications: Valuable Evidence Amid Complex Etiologies" by Alisse Hauspurg, Efe Cudjoe, and Emily S. Miller.

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JAMA @jama.com · 2d

Myo-inositol supplementation during pregnancy did not reduce the incidence of a composite of gestational #diabetes, #preeclampsia, or preterm birth in patients with #PCOS.

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Infographic from JAMA on myo-inositol supplementation during pregnancy in women with PCOS. It concludes supplementation didn't reduce gestational diabetes, preeclampsia, or preterm birth. Includes patient stats, intervention details, and outcome rates.

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JAMA @jama.com · 2d

Approximately 5 million adult #Medicaid beneficiaries risk losing coverage due to HR 1's work requirements, with a substantial portion having chronic conditions, particularly among those aged 50 to 64.

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A research letter from JAMA, published online October 1, 2025, titled "Clinical Characteristics of Adults at Risk of Medicaid Disenrollment Due to HR 1 Work Requirements." The letter discusses the impact of HR 1 on Medicaid recipients.

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JAMA @jama.com · 2d

🎙️ In the latest episode of JAMA Editor's Summary, Deputy Editors Linda Brubaker, MD, and Christopher C. Muth, MD, discuss the latest science published in JAMA.

Listen now: ja.ma/48hExMX

Intratracheal Budesonide for BPD, Cell and Gene Therapy Access, Moderate Alcohol Consumption and Health, and more

Editor’s Summary by Linda Brubaker, MD, and Christopher C. Muth, MD, Deputy Editors of JAMA, the Journal of the American Medical Association, for articles published from September 27-October 3, 2025.

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JAMA @jama.com · 3d

💬 Viewpoint: Recognizing primordial care, the stage of self-guided health actions before seeing a clinician, can improve safety and health outcomes.

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A JAMA viewpoint titled 'Primordial Care—The Space in Between' by Beverly G. Tchang, MD, published online October 6, 2025. It includes links to author affiliations and article information.

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JAMA @jama.com · 3d

💬 Viewpoint: By recognizing and addressing periods of uncertainty, temporal medicine helps restore agency and improve quality of life for patients with episodic illnesses.

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JAMA @jama.com · 3d

Inhaler-related #greenhouse gas emissions in the VA health system dropped 68% from 2008 to 2023, primarily due to policy and formulary changes favoring lower-emission inhaler options.

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Greenhouse gas emissions from inhaled medications, 2008-2023. Emissions from SAMA & SABA-SAMA decreased, ICS-LABA increased, SABA stable. Key events: CFC inhaler phase-out, VA formulary changes favoring DPI over MDI.

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JAMA @jama.com · 3d

"Inhalers may be among the most promising opportunities for health sector decarbonization."

Learn more in this Editorial. ja.ma/47cKxW0

JAMA editorial: "Rethinking Inhalers in the Era of Climate Change" by Alexander S. Rabin, MD, Jyothi Tirumalasetty, MD, and Stephanie I. Maximous, MD, MS. Published online October 6, 2025. DOI: 10.1001/jama.2025.17819.

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JAMA @jama.com · 3d

From 2014 to 2024, 1.6 billion inhalers for #asthma and #COPD dispensed in the US generated 24.9 million metric tons of CO₂e, with metered-dose inhalers responsible for 98% of emissions and $5.7 billion in social costs.

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Figure 1: Inhaler Utilization and Greenhouse Gas Emissions by Therapeutic Class, 2014-2024. Two bar graphs compare inhaler types (short-acting β-agonists, inhaled corticosteroids, etc.) against inhalers dispensed and greenhouse gas emissions.

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JAMA @jama.com · 3d

💬 Viewpoint: Mifepristone is frequently mislabeled solely as the "abortion pill," overshadowing its critical and diverse medical uses in managing various pregnancy-related complications and beyond.

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A JAMA Network webpage features a viewpoint article titled "The Clinical Indications for Mifepristone Go Beyond Abortion" by Jessica Chen, MD. Published online August 28, 2025.

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