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Judit Burgaya @jburgaya.bsky.social · 7d

On Wednesday I started my postdoc at the Institut für Infektionskrankheiten (IFIK) @unibe.ch 🧬💻 Excited to get started on my project exploring Streptococcus pneumoniae virulence and all the science ahead!

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Reposted by Judit Burgaya

Zamin Iqbal @zaminiqbal.bsky.social · 14d

Delighted to see our paper studying the evolution of plasmids over the last 100 years, now out! Years of work by Adrian Cazares, also Nick Thomson @sangerinstitute.bsky.social - this version much improved over the preprint. Final version should be open access, apols.
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Reposted by Judit Burgaya

Kate Baker @ksbakes.bsky.social · Aug 27

Awesome to see the transparent, systematic, and evidence-based approach behind the WHO Bacterial Priority Pathogens List 2024 out in the Lancet Infectious Diseases www.thelancet.com/journals/lan...

The WHO Bacterial Priority Pathogens List 2024: a prioritisation study to guide research, development, and public health strategies against antimicrobial resistance

The 2024 WHO BPPL is a key tool for prioritising research and development investments and informing global public health policies to combat AMR. Gram-negative bacteria and rifampicin-resistant M tuber...

www.thelancet.com

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Judit Burgaya @jburgaya.bsky.social · Jul 3

Truly honored to receive the Infection Biology PhD Prize. Grateful for the support @resist-cluster.bsky.social

Exzellenzcluster RESIST @resist-cluster.bsky.social · Jul 3

Congratulations! Judit Burgaya Ventura, PhD, received the "Infection Biology PhD Prize" for her doctoral thesis "On the use of bacterial genome sequencing in studying pathogenicity and transmission in clinical settings". The prize is supported by RESIST. The photo shows her with Prof. Förster.

Judit Burgaya @jburgaya.bsky.social · Jul 1

PhD, done 🥹🥂 Massive thanks to my brilliant supervisor @mgalactus.bsky.social and amazing colleagues!

Marco Galardini @mgalactus.bsky.social · Jul 1

Yesterday we had not one, but two PhD defenses! @jburgaya.bsky.social and Hannes held their own against the though questions from their examiners and are (provisionally) done with their PhD. We also had a pleasant surprise, with Judit winning the Infection Biology PhD prize! Congrats to both!

A photo of Hannes and Judit and their PhD graduation hats

A photo of Judit receiving the check for the "Infection Biology PhD" prize

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Reposted by Judit Burgaya

Marco Galardini @mgalactus.bsky.social · Jun 11

Are you interested what proportion of differentially expressed genes in bacteria can be explained by cis non-coding variants? Then head over to our latest preprint, in which Bamu used her dry- and wet-lab skills to answer this and other related questions!

www.biorxiv.org/content/10.1...

Cis non-coding genetic variation drives gene expression changes in the E. coli and P. aeruginosa pangenomes

Bacteria use gene regulation to dynamically adapt to changes in their environment, including resistance to stress and the occupation of new niches. Gene expression is known to vary within a species pa...

www.biorxiv.org

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Reposted by Judit Burgaya

Marco Galardini @mgalactus.bsky.social · May 21

We are very happy to report that the 3rd and 4th PhD theses from the lab have been submitted!

This time we had a “tale of two theses”: @jburgaya.bsky.social had her thesis 99% ready more than a week before the deadline (!), while Hannes preferred to wait until just before it was due ☕

Congrats!

A double photo of Judit and Hannes and their submitted PhD thesis. Both are smiling

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Reposted by Judit Burgaya

Alvaro San Millan @sanmillan.bsky.social · May 15

New opinion paper from the lab!

www.cell.com/trends/micro...

Plasmid–bacteria associations in the clinical context

Antimicrobial resistance (AMR) is one of the most pressing global health problems, with plasmids playing a central role in its evolution and dissemination. Over the past decades, many studies have inv...

www.cell.com

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Reposted by Judit Burgaya

Jörg Vogel @jorg-vogel-lab.bsky.social · May 5

And this only the beginning! I’m glad we did that collaboration with the Maric lab. ASOs for the people!

Giorgia Danti @giorgiadanti.bsky.social · May 5

First post, first paper 🤭
Proud to share with all of you our work on mRNA blocking using our own high-throughput antisense approach! doi.org/10.1002/advs...

Many thanks to @hmariclab.bsky.social, @jorg-vogel-lab.bsky.social and especially Linda for the amazing collaboration 😸

High‐Throughput Tiling of Essential mRNAs Increases Potency of Antisense Antibiotics

The systematic tiling of essential genes’ mRNA here presented, proposes a valuable tool for the identification of novel PNA sequences with antibiotic potential. The high-throughput synthetic set up o...

doi.org

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Reposted by Judit Burgaya

Tami Lieberman @contaminatedsci.bsky.social · May 1

Do people in the same household share strains when they have the same species?

How many cells transmit when a strain is shared?
Can strain composition be dynamic when species composition is stable?

We answer these and related questions for the facial skin microbiome in our latest paper.

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Reposted by Judit Burgaya

Willem van Schaik @wvschaik.bsky.social · Apr 29

This is fascinating, but also terrible news regarding antimicrobial resistance in multidrug-resistant Gram-positives

'Emergence of transferable daptomycin resistance in Gram-positive bacteria'

www.nature.com/articles/s44...

Emergence of transferable daptomycin resistance in Gram-positive bacteria - npj Antimicrobials and Resistance

npj Antimicrobials and Resistance - Emergence of transferable daptomycin resistance in Gram-positive bacteria

www.nature.com

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Reposted by Judit Burgaya

Sonja Lehtinen @sonjalehtinen.bsky.social · Apr 7

New paper: long-term trends in antibiotic resistance show signs of stabilisation (thread). journals.plos.org/plospathogen...

The evolution of antibiotic resistance in Europe, 1998–2019

Author summary Antibiotic resistance is an important public health threat: resistant infections are currently associated with 5 million deaths per year globally. This burden may increase further in th...

journals.plos.org

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Reposted by Judit Burgaya

Exzellenzcluster RESIST @resist-cluster.bsky.social · Feb 12

Properties of bacteria are constantly changing. @mgalactus.bsky.social is developing methods to better predict the properties. His team has now developed software that facilitates genome-wide association studies #GWAS Congratulations to all 🧫🦠😊
www.resist-cluster.de/en/better-pr...

Better prediction of bacterial properties

Each bacterial species has not just a single genome, but a diverse ensemble of gene combinations. This means that the properties of bacteria are constantly changing – for example, how ill they can mak...

www.resist-cluster.de

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Reposted by Judit Burgaya

Marco Galardini @mgalactus.bsky.social · Feb 12

We even got the press office to take this lovely photo of the three main authors :) Quite nice that we got it published on the International Day of Women and Girls in Science!

A photo of Judit, Jenny, and Bamu "working" hard on the pipeline

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Reposted by Judit Burgaya

Marco Galardini @mgalactus.bsky.social · Feb 12

Our paper describing the microGWAS pipeline was published yesterday in Microbial Genomics. Lots of fixes and additions to the code/documentation since the preprint, including a hard to reproduce bug that only showed up in a specific HPC 🥵

www.microbiologyresearch.org/content/jour...

microGWAS: a computational pipeline to perform large-scale bacterial genome-wide association studies

Identifying genetic variants associated with bacterial phenotypes, such as virulence, host preference and antimicrobial resistance, has great potential for a better understanding of the mechanisms inv...

www.microbiologyresearch.org

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