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James Pang @jchrispang.bsky.social · Jun 20

If you’re attending #OHBM2025 and will be your first time visiting Brisbane, this is an amazing resource created by the student and postdoc group

OHBM Trainees @ohbmtrainees.bsky.social · Jun 19

To everyone travelling to Brisbane for OHBM, we have some travel tips for you! Including OHBM airtravel discounts from the airport, budget-friendly ideas for food and entertainment, we want everyone to have a fun and enjoyable time.

medium.com/@ohbmtrainee...
Credit: Analia Marzoratti

How to Get Excited & Prepared for OHBM 2025 in Brisbane

Written by Analia Marzoratti

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James Pang @jchrispang.bsky.social · May 18

Due to unforeseen circumstances, we've extended the deadline to apply for our Systems and Comp Neuro postdoc position by a week (new deadline: May 25)! 🥳

If you have experience in modelling brain dynamics &/or analysing (s, d, f)MRI, we want you! Please help spread the word 👇

James Pang @jchrispang.bsky.social · Apr 17

We are hiring!

@aurinaarn.bsky.social and I are jointly looking for a talented Postdoc in Systems and Comp Neuro at Monash (AUS).

If you like neuroimaging 🧠, comp models 💻, genetics 🧬, brain disorders 🤕, and/or evolution 🐵🐭, this could be the job for you!!

careers.pageuppeople.com/513/cw/en/jo...

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James Pang @jchrispang.bsky.social · May 12

Applications for our postdoc position closes in 6 days! (Deadline: May 18 11:55pm AEST)

If you are interested in MRI, modelling of brain dynamics, and genetics in health, disease, or across evolution, we would love for you to join our team👇👇

James Pang @jchrispang.bsky.social · Apr 17

We are hiring!

@aurinaarn.bsky.social and I are jointly looking for a talented Postdoc in Systems and Comp Neuro at Monash (AUS).

If you like neuroimaging 🧠, comp models 💻, genetics 🧬, brain disorders 🤕, and/or evolution 🐵🐭, this could be the job for you!!

careers.pageuppeople.com/513/cw/en/jo...

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James Pang @jchrispang.bsky.social · Apr 17

Please share with anyone who you think might be interested

@ohbm-australia.bsky.social @acnsau.bsky.social @ausneurosoc.bsky.social @ohbmtrainees.bsky.social

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James Pang @jchrispang.bsky.social · Apr 17

The job is for at least two years, and we're looking for someone who can start before the end of the year.

Job ad closes on May 28 (see link for details).

DM or email me at james{dot}pang1@monash{dot}edu for further questions.

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James Pang @jchrispang.bsky.social · Apr 17

We are hiring!

@aurinaarn.bsky.social and I are jointly looking for a talented Postdoc in Systems and Comp Neuro at Monash (AUS).

If you like neuroimaging 🧠, comp models 💻, genetics 🧬, brain disorders 🤕, and/or evolution 🐵🐭, this could be the job for you!!

careers.pageuppeople.com/513/cw/en/jo...

Job Search

careers.pageuppeople.com

2 25 29

James Pang @jchrispang.bsky.social · Feb 5

🐷🧠

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James Pang @jchrispang.bsky.social · Feb 3

Average should be fine

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James Pang @jchrispang.bsky.social · Feb 3

Send me some 🐷 brains to add to the library 😆😆

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James Pang @jchrispang.bsky.social · Feb 3

Thanks!

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James Pang @jchrispang.bsky.social · Feb 3

Thanks!

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James Pang @jchrispang.bsky.social · Feb 3

Thanks!

Reposted by James Pang

Alessandro Gozzi @gozziale.bsky.social · Feb 2

Geometric influences on the regional organization of the mammalian brain (!)

Great new work lead by James Pang,
@alexfornito.bsky.social & star collaborators!

www.biorxiv.org/content/10.1...

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James Pang @jchrispang.bsky.social · Feb 3

For anyone interested in using our methods, the paper's associated GitHub page will be released soon.

In the meantime, check out the preprint's main text and supps for all the juicy details. Can also send a DM or email at james{dot}pang1{at}monash{dot}edu for more info. (15/n)

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James Pang @jchrispang.bsky.social · Feb 3

We started this in 2021, so it has been a long 4 yr study! Big thanks to @alexfornito.bsky.social PRobinson @kevinaquino.bsky.social PLevi @dralexholmes.bsky.social MMarkicevic XShen TFunck NPalomero RKong @bttyeo.bsky.social JTiego MBellgrove @toddc.bsky.social ELake @drbreaky.bsky.social (14/n)

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James Pang @jchrispang.bsky.social · Feb 3

In summary, this work points to a fundamental role that geometry plays not just in shaping brain function but also in its regional organization that is conserved across the mammalian species. (13/n)

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James Pang @jchrispang.bsky.social · Feb 3

We find highly robust correspondence between model solutions vs geometric modes and model parcs vs geometric parcs, demonstrating that the reaction-diffusion process may represent a conserved developmental mechanism for establishing the regional organization of the brain. (12/n)

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James Pang @jchrispang.bsky.social · Feb 3

We want to go further and provide mechanistic insights into why our geometric parcellations work so well. Hence, we go back to the initial motivation of this study and develop a computational model that mimics the reaction and diffusion of patterning molecules. (11/n)

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James Pang @jchrispang.bsky.social · Feb 3

Fourth, we can even go to the individual level, only needing individual-specific cortical surfaces. (10/n)

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James Pang @jchrispang.bsky.social · Feb 3

Third, the approach and homogeneity results are generalizable to non-neocortical structures such as subcortical and allocortical structures (i.e., HIP, AMY, THA, NAc, GP, PUT, CAU). (9/n)

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James Pang @jchrispang.bsky.social · Feb 3

Second, thanks to the data in the beautiful study of Schwartz et al. (2023, Nat Comms), we show that we can generate parcs for 24 other mammalian species, covering the Primata, Scandentia, Dermoptera, Rodentia, and Lagomorpha orders. Most don't even have parcs to date! (8/n)

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James Pang @jchrispang.bsky.social · Feb 3

The great thing about our approach is that it only requires T1w MRI, so it is highly generalizable!

First, it is generalizable to mammals (macaque, marmoset, mousse neocortices), with superior homogeneity against 15 existing parcs across 114 FC and non-FC phenotypes. (7/n)

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James Pang @jchrispang.bsky.social · Feb 3

We also find that the homogeneity of the geometric parcs remains superior across 242 non-FC cortical phenotypes, covering diverse properties of morphometry, microstructure, cytoarchitecture, metabolism, gene expression, chemoarchitecture, and fMRI task activations! (6/n)

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James Pang @jchrispang.bsky.social · Feb 3

Focusing first on the human neocortex, we find that the geometric parcs produce regions that are more functionally homogeneous (FC based on 3 independent resting-state fMRI datasets) than those in nearly all 17 cortical parcs commonly used in the field. (5/n)

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James Pang @jchrispang.bsky.social · Feb 3

Inspired by this equivalence, we use the geometric eigenmodes (which can be derived directly from T1w MRI) to develop a simple, hierarchical approach for generating a multiscale parcellation of any brain structure. We term as geometric parcellations. (4/n)

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