J.-F. Cavalier
@jefcavalier.bsky.social
170 followers
78 following
10 posts
Research Director in Medicinal Biochemistry (mycobacteria, Mtb, M.abscessus, antibacterials, lipolytic enzyme inhibitors, medicinal chemistry, chemobiology) at LISM UMR7255 CNRS, Marseille
https://tuberculosis-lbp.wixsite.com/tuberculosis-lbpteam/lbp-team
Posts
Media
Videos
Starter Packs
Reposted by J.-F. Cavalier
Reposted by J.-F. Cavalier
J.-F. Cavalier
@jefcavalier.bsky.social
· Jun 25
The polyamino‐isoprenyl enhancer NV716 enables the antibacterial activity of two families of multi‐target inhibitors against the ESKAPEE bacterium Enterobacter cloacae
Gram-negative bacteria are particularly prone to developing antimicrobial resistance (AMR), as evidenced by the WHO's ESKAPEE list of high-priority pathogens. One strategy that has increased is the u...
onlinelibrary.wiley.com
J.-F. Cavalier
@jefcavalier.bsky.social
· May 29
Mapping of Mycobacterial Enzymes Involved in Triacylglycerol Accumulation as Intrabacterial Lipid Inclusions Using Activity-Based Multitarget Inhibitor Probes
Lipids play a critical role in the physiology, life cycle, and pathogenicity of mycobacteria. They largely participate in host–pathogen interactions and fulfill important functions ranging from cell w...
pubs.acs.org
J.-F. Cavalier
@jefcavalier.bsky.social
· Apr 25
Synthesis and Anti-mycobacterial Activity of Novel Medium-chain β-Lactone Derivatives: A Multi-Target Strategy to combat Mycobacterium abscessus
The constant emergence of drug-resistant mycobacteria, together with the lack of new antibiotics entering the market, has become a global public health problem that threatens the effective treatment o...
pubs.rsc.org
J.-F. Cavalier
@jefcavalier.bsky.social
· Apr 22
Potency of all-D amino acid antimicrobial peptides derived from the bovine rumen microbiome on tuberculous and non-tuberculous mycobacteria
Despite the availability of antibiotics, tuberculosis (TB), caused by Mycobacterium tuberculosis, was once again declared the world's leading cause of…
www.sciencedirect.com
Reposted by J.-F. Cavalier
Reposted by J.-F. Cavalier
Kimberly Beatty
@beattylab.bsky.social
· Apr 16
Proteomic characterization of Mycobacterium tuberculosis subjected to carbon starvation | mSystems
Tuberculosis is a devastating human disease that kills over 1.2 million people a year.
This disease is caused by the bacterial pathogen Mycobacterium tuberculosis (Mtb). Mtb excels at surviving in the...
journals.asm.org
J.-F. Cavalier
@jefcavalier.bsky.social
· Feb 26
Reposted by J.-F. Cavalier
Reposted by J.-F. Cavalier
Reposted by J.-F. Cavalier
Reposted by J.-F. Cavalier
J.-F. Cavalier
@jefcavalier.bsky.social
· Nov 23
An mRNA Display Approach for Covalent Targeting of a Staphylococcus aureus Virulence Factor
Staphylococcus aureus ( S. aureus ) is an opportunistic human pathogen that causes over one million deaths around the world each year. We recently identified a family of serine hydrolases termed fluor...
www.biorxiv.org
Reposted by J.-F. Cavalier
Olivier Neyrolles
@oneyrolles.bsky.social
· Nov 11