Tianrun Jerry Li
@jerrytli.bsky.social
PhD in Plant pathology, UC Davis
Reposted by Tianrun Jerry Li
Really excited to join Stanford ChemE this September! We'll engineer proteins in plant immune and hormone pathways, combining high-throughput directed evolution with ML. Our goal is to enhance climate stress resilience and disease resistance in crops: rim.stanford.edu
Harnessing synthetic biology to engineer resilient crops
rim.stanford.edu
August 20, 2025 at 4:37 PM
Really excited to join Stanford ChemE this September! We'll engineer proteins in plant immune and hormone pathways, combining high-throughput directed evolution with ML. Our goal is to enhance climate stress resilience and disease resistance in crops: rim.stanford.edu
I’m honored to share the illustration accompanying our receptor engineering paper in Nature Plants. Created by the talented Phoebe Sinner from the Coaker lab, this artwork elegantly highlights how natural diversity contributes to differences in receptor specificity.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
August 20, 2025 at 5:02 AM
I’m honored to share the illustration accompanying our receptor engineering paper in Nature Plants. Created by the talented Phoebe Sinner from the Coaker lab, this artwork elegantly highlights how natural diversity contributes to differences in receptor specificity.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Happy to share that the last piece of my thesis is finally out! Here, we designed and delivered a dual PRR stack in potato to control vector-borne and soil-borne bacterial pathogens, Ca. Liberibacter solanacearum and Ralstonia solanacearum. onlinelibrary.wiley.com/doi/10.1111/...
Introducing Pattern Recognition Receptors in Potato Confers Enhanced Resistance to Ralstonia solanacearum but Not a Vector Borne Pathogen
Click on the article title to read more.
onlinelibrary.wiley.com
August 19, 2025 at 12:31 PM
Happy to share that the last piece of my thesis is finally out! Here, we designed and delivered a dual PRR stack in potato to control vector-borne and soil-borne bacterial pathogens, Ca. Liberibacter solanacearum and Ralstonia solanacearum. onlinelibrary.wiley.com/doi/10.1111/...
It’s my great honor to be part of this project and happy to see this part of my thesis work finally out in Nature Plants!
Excited this paper is finally published! We focused on the inner concave surface of LRR RKs to expand bacterial flagellin perception in plants. Selection indicates expanded perception is more common than previously thought. Experiments led by @jerrytli.bsky.social www.nature.com/articles/s41...
Unlocking expanded flagellin perception through rational receptor engineering - Nature Plants
Receptor kinase FLS2 detects the flg22 epitope of bacterial flagellin. Here the authors identify key residues on FLS2’s concave surface that enable expanded perception of flg22 variants, allowing the ...
www.nature.com
July 29, 2025 at 12:11 PM
It’s my great honor to be part of this project and happy to see this part of my thesis work finally out in Nature Plants!
Reposted by Tianrun Jerry Li
#2025ISMPMI 📣 In silico screening of PRR-epitope interactions is now possible!
Here, we developed mamp-ml to predict their immunogenic outcomes without structural context. Let's accelerate engineering plant receptors for robust resistance! 🚀🌱 Small 🧵
www.biorxiv.org/content/10.1...
Here, we developed mamp-ml to predict their immunogenic outcomes without structural context. Let's accelerate engineering plant receptors for robust resistance! 🚀🌱 Small 🧵
www.biorxiv.org/content/10.1...
mamp-ml: A deep learning approach to epitope immunogenicity in plants
Eukaryotes detect biomolecules through surface-localized receptors, key signaling components. A subset of receptors survey for pathogens, induce immunity, and restrict pathogen growth. Comparative gen...
www.biorxiv.org
July 15, 2025 at 11:28 PM
#2025ISMPMI 📣 In silico screening of PRR-epitope interactions is now possible!
Here, we developed mamp-ml to predict their immunogenic outcomes without structural context. Let's accelerate engineering plant receptors for robust resistance! 🚀🌱 Small 🧵
www.biorxiv.org/content/10.1...
Here, we developed mamp-ml to predict their immunogenic outcomes without structural context. Let's accelerate engineering plant receptors for robust resistance! 🚀🌱 Small 🧵
www.biorxiv.org/content/10.1...