Jesper Madsen
@jespergrud.bsky.social
Associate Professor @ University of Southern Denmark. Computational Biologist working with ML to understand transcriptional and genetic regulation of metabolic disease.
Pinned
Jesper Madsen
@jespergrud.bsky.social
· Feb 1
Single cell-resolved transcriptional dynamics of human subcutaneous adipose tissue during lifestyle- and bariatric surgery-induced weight loss
During sustained weight gain, human white adipose tissue undergoes dramatic remodeling that may compromise adipose tissue function and lead to obesity comorbidities such as cardiometabolic disease. Th...
www.biorxiv.org
Preprint alert! We used snRNA-seq on adipose tissue from a longitudinal cohort of people undergoing surgury-induced weight loss. True ATLAS team effort
We found dramatic changes in immune and progenitor compartments. Give it a read and let us know what you think.
www.biorxiv.org/content/10.1...
We found dramatic changes in immune and progenitor compartments. Give it a read and let us know what you think.
www.biorxiv.org/content/10.1...
Excited to share DeepDive, a generative model for disentangling covariate effects in snATAC-seq developed by the amazing @andreasfm.bsky.social. DeepDive enables deeper understanding of a dataset by separating the effects of known and unknown covariates. Here are some highlights. 1/6
October 7, 2025 at 12:40 PM
Excited to share DeepDive, a generative model for disentangling covariate effects in snATAC-seq developed by the amazing @andreasfm.bsky.social. DeepDive enables deeper understanding of a dataset by separating the effects of known and unknown covariates. Here are some highlights. 1/6
Reposted by Jesper Madsen
Check out our latest paper now online at Cell Metabolism: Hepatic stellate cells regulate liver fatty acid utilization via plasmalemma vesicle-associated protein. Amazing work by Daniel, Jasmin, Christian, Peter, Oliver from @ravnskjaer_lab, and many more 🏆💐♥️
www.cell.com/cell-metabol...
www.cell.com/cell-metabol...
Hepatic stellate cells regulate liver fatty acid utilization via plasmalemma vesicle-associated protein
Hansen et al. show that the hepatic stellate cell-expressed plasmalemma vesicle-associated
protein is required for the normal switch from carbohydrate to lipid utilization during
fasting. This reveals...
www.cell.com
March 3, 2025 at 3:57 PM
Check out our latest paper now online at Cell Metabolism: Hepatic stellate cells regulate liver fatty acid utilization via plasmalemma vesicle-associated protein. Amazing work by Daniel, Jasmin, Christian, Peter, Oliver from @ravnskjaer_lab, and many more 🏆💐♥️
www.cell.com/cell-metabol...
www.cell.com/cell-metabol...
Preprint alert! We used snRNA-seq on adipose tissue from a longitudinal cohort of people undergoing surgury-induced weight loss. True ATLAS team effort
We found dramatic changes in immune and progenitor compartments. Give it a read and let us know what you think.
www.biorxiv.org/content/10.1...
We found dramatic changes in immune and progenitor compartments. Give it a read and let us know what you think.
www.biorxiv.org/content/10.1...
Single cell-resolved transcriptional dynamics of human subcutaneous adipose tissue during lifestyle- and bariatric surgery-induced weight loss
During sustained weight gain, human white adipose tissue undergoes dramatic remodeling that may compromise adipose tissue function and lead to obesity comorbidities such as cardiometabolic disease. Th...
www.biorxiv.org
February 1, 2025 at 8:44 AM
Preprint alert! We used snRNA-seq on adipose tissue from a longitudinal cohort of people undergoing surgury-induced weight loss. True ATLAS team effort
We found dramatic changes in immune and progenitor compartments. Give it a read and let us know what you think.
www.biorxiv.org/content/10.1...
We found dramatic changes in immune and progenitor compartments. Give it a read and let us know what you think.
www.biorxiv.org/content/10.1...