Peng Jiang Lab@Rutgers
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jianglab.bsky.social
Peng Jiang Lab@Rutgers
@jianglab.bsky.social
170 followers 180 following 14 posts
Create hPSC #organoid brain & #chimeric brain to study #neurodevelopment, #aging, #DownSyndrome, #Alzheimers, & #Autism; develop #glial cell replacement therapies. https://cbn.rutgers.edu/peng-jiang-lab/339-peng-jiang-lab
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jianglab.bsky.social
Peng Jiang Lab@Rutgers @jianglab.bsky.social · 2d
An idea we started in 2019 is now published in @natneuro.nature.com! Excited to share our new study: rdcu.be/eRvdA

Congrats to Mengmeng Jin and our team! Heartfelt thanks to all collaborators for their support, and to the reviewers for their insightful comments!
jianglab.bsky.social
An idea we started in 2019 is now published in @natneuro.nature.com! Excited to share our new study: rdcu.be/eRvdA

Congrats to Mengmeng Jin and our team! Heartfelt thanks to all collaborators for their support, and to the reviewers for their insightful comments!
November 24, 2025 at 2:17 PM
jianglab.bsky.social
Thrilled to share our review just published in @cp-neuron.bsky.social ! 🎉
Big shoutout to Ava, Mengmeng, and our entire team!
authors.elsevier.com/a/1k-uh3BtfH...
April 28, 2025 at 4:18 PM
Reposted by Peng Jiang Lab@Rutgers
elizabethhead.bsky.social
Hopefully a little inspiration for our trainees...this was led by an amazing postdoc at UPitt..Dr. Jean Liou
March 7, 2025 at 12:54 AM
jianglab.bsky.social
Advancements in 3D models for studying human iPSC-microglia: Insights ... www.sciencedirect.com/science/arti...
Advancements in 3D models for studying human iPSC-microglia: Insights into neurodevelopment and neurological disorders
Microglia are immune cells of the central nervous system, playing a vital role in brain development, homeostasis, and disease. When these cells become…
www.sciencedirect.com
February 8, 2025 at 4:53 PM
Reposted by Peng Jiang Lab@Rutgers
cp-neuron.bsky.social
ApoE3 R136S binds to Tau and blocks its propagation, suppressing neurodegeneration in mice with Alzheimer’s disease
Guiqin Chen, Mengmeng Wang, et al. demonstrate that ApoE3 R136S inhibits AEP-mediated Tau cleavage and neuroinflammation by binding more tightly to Tau, preventing its propagation, and thereby slowing the progression of Alzheimer’s disease in mice.
dlvr.it
January 15, 2025 at 12:08 AM
Reposted by Peng Jiang Lab@Rutgers
lukensjohnr.bsky.social
Human longevity and Alzheimer’s disease variants act via microglia and oligodendrocyte gene networks
academic.oup.com/brain/advanc...
Human longevity and Alzheimer’s disease variants act via microglia and oligodendrocyte gene networks
Graham et al. show that Alzheimer's disease-associated genetic variants are enriched in gene networks expressed by microglia and oligodendrocytes during ag
academic.oup.com
January 13, 2025 at 2:23 PM
jianglab.bsky.social
www.nature.com/articles/s41...
Monocyte-derived macrophages act as reinforcements when microglia fall short in Alzheimer’s disease - Nature Neuroscience
This article discusses a puzzling issue in brain pathology: why brain-resident microglia are insufficient for protection, and why myeloid cells are needed from the periphery. Several strategies are pr...
www.nature.com
January 7, 2025 at 2:10 PM